Texcol-dmd
Texcol-dmd Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Texcol-dmd is a brand name. Its generic name is Dextromethorphan + Diphenhydramine.
Introduction
Dextromethorphan/Diphenhydramine is a combination of two medicines: Dextromethorphan and Diphenhydramine. Dextromethorphan is a cough suppressant that acts on the brain to reduce the feeling of wanting to cough. Diphenhydramine is an antihistamine that blocks the effects of the naturally occurring chemical histamine in the body. Together, these two medicines are used to temporarily relieve cough, runny nose and sneezing caused by colds, hay fever, and upper respiratory allergies.Uses for Dextromethorphan/Diphenhydramine
Dextromethorphan/Diphenhydramine is used to temporarily relieve sore throat, coughing, sneezing, runny nose, and itchy or watery eyes caused by hay fever, other types of allergies, or the common cold. It is also used to suppress cough in adults aged 18 years and older with acute asthma.Mechanism of Action
Dextromethorphan/Diphenhydramine works by combining two different active ingredients; Dextromethorphan and Diphenhydramine. Dextromethorphan is a cough suppressant that acts on the brain to reduce the feeling of wanting to cough. Diphenhydramine is an antihistamine that blocks the effects of the naturally occurring chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. By blocking the effects of histamine, dextromethorphan/diphenhydramine helps to relieve those symptoms.How Long Does It Take to Work?
Dextromethorphan/Diphenhydramine usually begins to work within 15 to 30 minutes after taking it.Absorption
Dextromethorphan/Diphenhydramine is absorbed from the gastrointestinal tract, and reaches peak levels in the blood within 1 to 3 hours. The onset of action usually occurs after 15 to 30 minutes.Route of Elimination
Dextromethorphan/Diphenhydramine is eliminated mainly by the kidney.Dosage
Dextromethorphan/Diphenhydramine is available in oral and liquid forms, and is usually taken every 4 to 6 hours as needed. The recommended dose of Dextromethorphan/Diphenhydramine for adults and children 12 years of age and older is: • Oral: 30 mg/6.25 mg every 4 to 6 hours, or 60 mg/12.5 mg every 4 to 6 hours as needed • Oral liquid: 5 mL (30 mg/6.25 mg) every 4 to 6 hours, or 10 mL (60 mg/12.5 mg) every 4 to 6 hours as needed • Maximum daily dose: 120 mg/25 mg per day The recommended dose of Dextromethorphan/Diphenhydramine for children 6 to 11 years of age is: • Oral: 15 mg/3.125 mg every 4 to 6 hours • Oral liquid: 5 mL (30 mg/6.25 mg) every 4 to 6 hours • Maximum daily dose: 60 mg/12.5 mg per dayAdministration
Dextromethorphan/Diphenhydramine should be taken with a full glass of water. It may be taken with or without food.Side Effects
The most common side effects of Dextromethorphan/Diphenhydramine include: • Dry mouth • Drowsiness • Dizziness • Blurred vision • Headache • Nausea • Gastrointestinal upsetToxicity
Dextromethorphan/Diphenhydramine overdose may cause nervousness, restlessness, difficulty breathing, rapid heart rate, nausea, vomiting, and confusion. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you have taken an overdose of Dextromethorphan/Diphenhydramine.Precaution
• Dextromethorphan/Diphenhydramine should be used with caution in people with: • Glaucoma • Prostate enlargement • Stomach ulcer • Narrow-angle glaucoma • Heart problems • Kidney or liver problems • Difficulty urinating • Allergies to other medicationInteraction
Dextromethorphan/Diphenhydramine may interact with other medications such as sedatives, anticholinergics, antidepressants, antiseizure medications, monoamine oxidase inhibitors, antiarrhythmics, and opioids. Tell your doctor about all the medications you are taking to reduce the risk of interactions.Disease Interaction
Dextromethorphan/Diphenhydramine may worsen the symptoms of certain medical conditions such as asthma, glaucoma, and chronic obstructive pulmonary disease (COPD). Tell your doctor if you have any of these conditions before starting Dextromethorphan/Diphenhydramine.Drug Interaction
Dextromethorphan/Diphenhydramine may interact with other drugs such as blood thinners, sleeping pills, muscle relaxants, seizure medications, and antibiotics. Tell your doctor about all the drugs you are taking to reduce the risk of drug interactions.Food Interactions
Dextromethorphan/Diphenhydramine should be taken with a full glass of water. It may be taken with or without food.Pregnancy Use
Dextromethorphan/Diphenhydramine should not be used by pregnant women unless it is clearly needed and recommended by the doctor. Consult a doctor before using Dextromethorphan/Diphenhydramine during pregnancy.Lactation Use
It is not known whether Dextromethorphan/Diphenhydramine passes into breast milk. Tell your doctor if you are breastfeeding before using Dextromethorphan/Diphenhydramine.Acute Overdose
Overdose of Dextromethorphan/Diphenhydramine is very dangerous and can lead to serious side effects. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you have taken an overdose of Dextromethorphan/Diphenhydramine.Contraindication
Dextromethorphan/Diphenhydramine is contraindicated in individuals with hypersensitivity to either of its components.Use Direction
Follow the instructions on the medicine label or your doctor's directions. Do not take more than the recommended dose or for a longer time than advised. Do not take Dextromethorphan/Diphenhydramine with alcohol or other medicines containing alcohol.Storage Condition
Store this medication at room temperature away from heat, light, and moisture. Do not store in the bathroom. Do not keep outdated medicine or medicine no longer needed.Volume of Distribution
The volume of distribution of Dextromethorphan/Diphenhydramine is approximately 0.6 L/kg.Half Life
The half-life of dextromethorphan/diphenhydramine is 3–7 hours.Clearance
The total body clearance of dextromethorphan/diphenhydramine is approximately 0.3–1.5 L/hr/kg.Here you find in details version of Texcol-dmd