Neuciti Plus

Neuciti Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Neuciti Plus is a brand name. Its generic name is Piracetam + Citicoline.

Introduction

Piracetam and Citicoline are nootropic drugs commonly used to enhance cognitive performance, improve learning and reduce the damage caused by various neurological disorders. Piracetam is a drug that was developed in the 1960s to improve cognitive function and memory, while Citicoline, a more recent form of Piracetam, is a neuroprotective agent intended to improve nerve transmission and protect against oxidative stress.

Uses

Piracetam and Citicoline are used for a variety of purposes related to cognitive function and memory. Individuals with Alzheimer's disease, stroke, Down's Syndrome, multiple sclerosis, and other cognitive impairments may benefit from taking these two compounds. Additionally, they may also be beneficial for those wishing to improve their learning capabilities, increase concentration, and reduce stress and anxiety.

Mechanism of Action

Piracetam is thought to work by modulating receptors located on the surface of neurons. This allows the neurons to respond to various neurotransmitters in the brain. Citicoline also affects neuronal membrane receptors, but it primarily works by providing the building blocks for the synthesis of phospholipids, fatty acids, and neurotransmitters such as acetylcholine, dopamine, and serotonin.

How Long Does It Take To Work?

Most individuals generally notice improvements within 1-2 weeks of regular use. However, it may take several weeks for full effects to be seen and the duration of effect is highly variable between individuals.

Absorption

Piracetam is readily absorbed after oral administration with peak levels occurring in 30 minutes to 3 hours. Citicoline is well absorbed with peak concentrations occurring between 1-2 hours.

Route of Elimination

Piracetam is primarily eliminated through the kidneys, while Citicoline is eliminated mainly through the bile.

Dosage

Piracetam and Citicoline are available in oral, sublingual, and injectable forms. The recommended dosage of Piracetam is 1.2 to 4.8 g per day taken in 2-3 divided doses. The recommended dosage of Citicoline is 250 to 1,000 mg per day also taken in 2-3 divided doses.

Administration

Piracetam and Citicoline can be taken orally or sublingually. Injectable forms of Citicoline are also available, however these should only be used under the supervision of a physician.

Side Effect

The most commonly reported side effects are dizziness, headache, difficulty sleeping, drowsiness, and nausea. These symptoms tend to resolve after a few days of regular use.

Toxicity

There have been no reports of serious toxic effects associated with the use of Piracetam and Citicoline. Some mild side effects may occur when taking higher doses.

Precaution

Individuals with kidney or liver disease, high blood pressure, or heart problems should exercise caution when taking Piracetam and Citicoline. These drugs may also interact with other medications, so it is important to speak to a doctor before combining them with other drugs.

Interaction

  • Piracetamide may interact with choline to enhance or reduce efficacy.
  • Citicoline may interact with other drugs, supplements, or foods that also contain choline.

Disease Interaction

  • Piracetam may interact with anticoagulants or antiplatelet drugs and increase the risk of bleeding.
  • Citicoline may increase the risk of bleeding in those taking warfarin, aspirin, or other blood thinning medications.

Drug Interaction

  • Piracetam may interact with narcotic pain medication, muscle relaxers, and other seizure medication.
  • Citicoline may increase the effects of certain psychoactive drugs, such as benzodiazepines, antidepressants, and antipsychotic medications.

Food Interactions

  • Piracetam and Citicoline are not known to interact significantly with most foods, however it is best to take them with food as it may help reduce stomach upset.

Pregnancy Use

Piracetam and Citicoline are not recommended for use in pregnant women due to the lack of safety data.

Lactation Use

Piracetam and Citicoline are not recommended for use in lactating women due to the lack of safety data.

Acute Overdose

A single dose of up to 3g of Piracetam or 1.5g of Citicoline is considered to be non-toxic. However, consuming larger amounts may lead to acute toxicity.

Contraindication

The use of Piracetam and Citicoline is contraindicated in individuals taking monoamine oxidase inhibitors, as this may increase the risk of serious adverse effects.

Use Direction

Piracetam and Citicoline should be taken as directed by a healthcare professional. It is generally advised to take the medication with food. Dosage should be tailored to the individual's needs.

Storage Condition

Piracetam and Citicoline should be stored at room temperature away from direct light and moisture.

Volume of Distribution

The volume of distribution of Piracetam is unknown, however Citicoline has a volume of distribution of approximately 2-3 L/kg.

Half Life

The half life of Piracetam is approximately 5-6 hours, while the half life of Citicoline is about 1-2 hours.

Clearance

Piracetam is primarily eliminated through the kidneys, while Citicoline is eliminated mainly through the bile.

Here you find in details version of Neuciti Plus

Some Frequently Asked Questions About Neuciti Plus

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What is Piracetam and Citicoline?

Piracetam and citicoline are commonly used cognitive enhancers or nootropics. Piracetam is a cognitive enhancer that is used to improve memory, focus, and mental clarity while citicoline is believed to support brain health and cognitive function.

What are the benefits of Piracetam and Citicoline?

The primary benefits of piracetam and citicoline include improved attention, mental clarity, focus, and memory. Additionally, they have been found to increase brain activity, mood, and can improve alertness.

Is Piracetam and Citicoline safe?

Yes, Piracetam and Citicoline are generally considered to be safe when used as directed. It is recommended to speak with your doctor before using cognitive enhancers, especially if you are taking other medications or have a pre-existing medical condition.

What is the dosage for Piracetam and Citicoline?

The recommended dosage for piracetam is 1,200 to 4,800 mg per day, typically split over 2-3 doses. The recommended dosage of citicoline is between 250 to 500 mg per day.

Do Piracetam and Citicoline have any side effects?

Though Piracetam and Citicoline are generally considered safe, some side effects have been reported, such as nausea, headaches, difficulty sleeping, and anxiety. It is generally recommended to start with a small dose and increase gradually to minimize chances of side effects.

How long does it take for Piracetam and Citicoline to start working?

The effects of Piracetam and Citicoline can vary from person to person, but many users begin to notice a difference within 30 minutes of taking them. However, more significant cognitive improvements may require several weeks to develop.

Are Piracetam and Citicoline Legal?

Piracetam and Citicoline are generally legal and unregulated in most countries, though regulations may vary by region. For example, Piracetam is classified as a medical drug in Germany, Australia, and some other countries.

What is the Difference between Piracetam and Citicoline?

The primary difference between Piracetam and Citicoline is their mechanism of action. Piracetam is a cognitive enhancer that primarily improves focus and mental clarity while citicoline is an effective brain health supplement that can support cognitive function.

What are Natural Sources of Piracetam and Citicoline?

Piracetam is synthesized in the laboratory and is not found in nature. While citicoline can be derived from natural sources like eggs, dairy, and meat, most citicoline supplements are synthesized in the laboratory.

Do I need a prescription to buy Piracetam and Citicoline?

In most countries, a prescription is not required to purchase Piracetam or Citicoline. They are generally available without a prescription as dietary supplements.

Do I need to cycle Piracetam and Citicoline?

Cycling is not necessarily required while taking Piracetam and Citicoline, though some users prefer to cycle their use to reduce tolerance. Generally speaking, taking a break from any nootropic can be beneficial to promote optimal effectiveness.

Can I mix Piracetam and Citicoline?

Yes, it is generally safe to take Piracetam and Citicoline together. This combination is thought to be synergistic and can be effective for improving cognitive performance.

Do Piracetam and Citicoline interact with any other drugs?

Piracetam and Citicoline may interact with other drugs, including some antidepressants, blood thinners, cholesterol-lowering medications, and anticoagulants. It is important to discuss with your doctor before taking any nootropic supplement if you are taking other medications or have a pre-existing medical condition.

What should I do if I experience any side effects while taking Piracetam and Citicoline?

If you experience any side effects while taking Piracetam or Citicoline, it is important to stop taking them and speak with your doctor. Additionally, it is recommended to start with a small dose and gradually increase to minimize the chances of side effects.

Can children take Piracetam and Citicoline?

Piracetam and Citicoline are not recommended for children and should only be used under the direction of a doctor. It is important to consult with your doctor before giving any cognitive enhancer supplement to a child.

What are the long-term effects of taking Piracetam and Citicoline?

Generally speaking, the long-term effects of taking Piracetam and Citicoline are thought to be beneficial. They are both commonly used cognitive enhancers that are believed to improve memory, focus, and mental clarity.

Can Piracetam and Citicoline be taken with other nootropics?

Yes, Piracetam and Citicoline can be taken with other nootropics. However, it is important to start with a low dose and gradually increase to minimize the chances of side effects. Additionally, it is recommended to speak with your doctor before combining any cognitive enhancers.

What is the best form of Piracetam and Citicoline to take?

The most common forms of Piracetam and Citicoline are powder and capsules. Capsules tend to be the most convenient form, while the powder is believed to absorb faster and provide more immediate effects.

How do I store Piracetam and Citicoline?

Piracetam and Citicoline should be stored in a cool, dry place away from direct light and moisture. It is important to store them in a sealed container to protect them from moisture and humidity.

Can I take Piracetam and Citicoline while pregnant?

Piracetam and Citicoline are not recommended for pregnant or breastfeeding women. Additionally, it is important to speak with your doctor before taking any cognitive enhancer supplement if you are pregnant or nursing.

Do I need to take Piracetam and Citicoline every day?

It is not necessary to take Piracetam and Citicoline every day. However, some users find it beneficial to take them on an as-needed basis or take them consistently for a few weeks to promote long-term cognitive improvements.

What time of day should I take Piracetam and Citicoline?

Ideally, Piracetam and Citicoline should be taken in the morning or early afternoon to optimize their effectiveness. Both supplements are known to promote mental clarity and alertness, so it is best to avoid taking them late in the evening to avoid interfering with sleep.

Do I need to take Piracetam and Citicoline with food?

It is generally recommended to take Piracetam and Citicoline with food to reduce the chances of stomach upset. However, it is not necessary and some users find it beneficial to take them on an empty stomach for more immediate effects.

Is there any research on Piracetam and Citicoline?

Yes, there is a substantial amount of scientific research to support the use of Piracetam and Citicoline as cognitive enhancers. Additionally, studies have been conducted to show their potential in treating age-related cognitive decline, memory loss, and other cognitive impairments.

Do I need to take a supplement with Piracetam and Citicoline?

Some users find it beneficial to take a choline supplement alongside Piracetam and Citicoline to support optimal cognitive performance. Choline is an essential nutrient that is necessary for proper brain function, and many users find it helpful to take additional choline while taking nootropic supplements.

Do Piracetam and Citicoline have any drug interactions?

Piracetam and Citicoline may interact with some medications, including antidepressants, blood thinners, cholesterol-lowering medications, and anticoagulants. It is always important to speak with your doctor before taking any cognitive enhancer supplement if you are taking other medications or have a pre-existing medical condition.

Are there any potential dangers of taking Piracetam and Citicoline?

While Piracetam and Citicoline are generally considered to be safe, some users may experience side effects, such as nausea, headaches, difficulty sleeping, and anxiety. It is important to start with a small dose and discuss with your doctor before taking any cognitive enhancer supplement.

What is the best way to take Piracetam and Citicoline?

The best way to take Piracetam and Citicoline is to start with a small dose and gradually increase over a period of days or weeks. Additionally, it is best to take them with food to reduce the chances of stomach upset and it is important to speak with your doctor before taking any nootropic supplement.

Can I overdose on Piracetam and Citicoline?

Though an overdose is unlikely, it is possible to experience side effects if too much is taken. It is important to follow the recommended dosage and speak with your doctor if you are experiencing any side effects.

What is the difference between Piracetam and Aniracetam?

Piracetam and Aniracetam are both commonly used nootropic supplements. Piracetam is a cognitive enhancer that is used to improve memory, focus, and mental clarity, while Aniracetam is an anxiolytic that is used to provide mental clarity and to reduce stress and anxiety.

Does Piracetam and Citicoline help with ADHD?

Piracetam and Citicoline may help to improve the cognitive symptoms of ADHD, such as focus, attention, and mental clarity. Additionally, they have been found to increase alertness and can help to reduce the side effects of certain ADHD medications.

Are Piracetam and Citicoline Vegan and Vegetarian-Friendly?

Yes, both Piracetam and Citicoline are vegan and vegetarian-friendly. Most Piracetam supplements are derived from synthetic sources and do not contain any animal-derived ingredients. Citicoline supplements are usually synthesized in the laboratory and are free from any animal-derived substances.

Are there any other cognitive enhancer supplements I should consider?

Yes, there are many cognitive enhancer supplements available on the market, such as Noopept, Bacopa Monnieri, Alpha-GPC, and L-Theanine. It is always important to speak with your doctor before taking any cognitive enhancer supplement.

Can Piracetam and Citicoline help relieve stress and anxiety?

Piracetam and Citicoline are commonly used cognitive enhancers that can help to improve focus, attention, and clarity. While they are not specifically designed to relieve stress and anxiety, they may help to reduce symptoms of stress and anxiety related to cognitive impairments.

Does Piracetam and Citicoline improve intelligence?

Piracetam and Citicoline have been found to improve focus, attention, and mental clarity. These cognitive benefits may improve intelligence, but it is important to note that they will not increase intelligence beyond one’s natural capabilities.

Can Piracetam and Citicoline help with depression?

Piracetam and Citicoline can help to improve mental clarity and focus, which may help to reduce the symptoms of depression. Additionally, they can be used in combination with antidepressant medications to improve their effectiveness.

What other supplements should I take with Piracetam and Citicoline?

Some supplements that can be taken with Piracetam and Citicoline include omega-3 fatty acids, choline, vitamin B12, magnesium, and antioxidants. It is important to speak with your doctor before taking any new supplements.

What are the most common forms of Piracetam and Citicoline?

The most common forms of Piracetam and Citicoline are powder and capsules. Capsules are the most convenient form, while the powder can absorb faster and provide more immediate effects.

Are there any cognitive enhancers that are not stimulants?