Neurospas Cd
Neurospas Cd Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Neurospas Cd is a brand name. Its generic name is Chlordiazepoxide + Clidinium + Dicycloverine / Dicyclomine.
Introduction
Chlordiazepoxide + Clidinium + Dicycloverine or Dicyclomine is a combination medication used to treat a variety of gastrointestinal conditions including irritable bowel syndrome (IBS) and Diverticular Disease. It is a non-opioid, centrally acting analgesic and antispasmodic drug with anticholinergic properties.Uses for
Chlordiazepoxide + Clidinium + Dicycloverine or Dicyclomine is used for the symptomatic relief of gastrointestinal conditions such as IBS and Diverticular Disease. It works to relieve abdominal cramping and improve bowel motiliety. It may also be used to manage nausea, vomiting, and other gastrointestinal symptoms.Mechanism of Action
The combination of Chlordiazepoxide + Clidinium + Dicycloverine or Dicyclomine works in a two-fold manner. Firstly, Chlordiazepoxide is a benzodiazepine with a sedative and anxiolytic (anti-anxiety) effect, helping to reduce muscle spasms and relieve abdominal cramping. Secondly, Clidinium and Dicycloverine (or Dicyclomine) are anticholinergic agents that block the action of acetylcholine, a neurotransmitter that contracts the muscles in the digestive tract. By blocking this action, the drug can reduce or eliminate abdominal cramping and improve bowel motility.How long does it take to work?
The effects of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) can be felt within 30-60 minutes after taking it. Maximum effects can typically be seen after 2-4 hours.Absorption
Chlordiazepoxide is rapidly absorbed after oral administration, with peak plasma concentrations typically reached within 1-3 hours. Clidinium and Dicycloverine (or Dicyclomine) are also rapidly absorbed after oral administration, with peak plasma concentrations typically reached within 1-2 hours.Route of Elimination
Chlordiazepoxide is metabolized by the liver and then eliminated mainly through the kidneys as metabolites and unchanged drug. Clidinium and Dicycloverine (or Dicyclomine) are both largely eliminated through the bile as metabolites and unchanged drug.Dosage
The recommended dosage of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) varies depending on the indication.- IBS & Diverticular Disease: The recommended dosage is 2 capsules three times per day, with or without food.
- Nausea & Vomiting: The recommended dosage is 1-2 capsules three times per day, with or without food.
Administration
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should be taken orally with water or other liquids. The capsules should not be crushed, chewed, or dissolved as this can alter the effects of the medication.Side Effects
Common side effects of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) may include:- Dry mouth
- Drowsiness
- Lightheadedness
- Nausea
- Constipation
- Tremors
- Fatigue
- Headache
- Blurred vision
- Rash
Toxicity
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) is generally well tolerated, though it has been shown to cause neurotoxicity when taken in overdose. Signs and symptoms of overdose may include: drowsiness, agitation, confusion, slurred speech, difficulty breathing, nausea, vomiting, and coma.Precautions
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should be used with caution in patients with narrow angle glaucoma, bladder obstruction or GI obstruction. It should also be used with caution in elderly patients and those with a history of substance abuse.Interactions
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) can interact with a variety of drugs including anticholinergics, narcotics, barbiturates, sedatives, alcohol, and MAO inhibitors. It is important to tell your doctor or pharmacist about all the drugs you are taking before taking this medication.Disease Interactions
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should not be used in patients with narrow angle glaucoma, bladder obstruction, GI obstruction, or a history of substance abuse.Drug Interactions
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) can interact with a variety of drugs including anticholinergics, narcotics, barbiturates, sedatives, alcohol, and MAO inhibitors.Food Interactions
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) can interact with certain foods such as alcohol and grapefruit juice. It is important to check with your doctor or pharmacist to see if there are any foods you should avoid while taking this medication.Pregnancy Use
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should not be used during pregnancy unless the benefits outweigh the risks.Lactation Use
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should be used with caution in breastfeeding women. It is not known if the drug is excreted into breastmilk.Acute Overdose
Signs and symptoms of an acute overdose of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) may include drowsiness, agitation, confusion, slurred speech, difficulty breathing, nausea, vomiting, and coma.Contraindication
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) is contraindicated in patients with narrow angle glaucoma, bladder obstruction or GI obstruction, and in those with a history of substance abuse.Use Direction
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should be taken orally with water or other liquids once or twice daily as instructed by a doctor. The capsules should not be crushed, chewed, or dissolved as this can alter the effects of the medication.Storage Condition
Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) should be stored at room temperature away from light, heat, and moisture.Volume of Distribution
The volume of distribution of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) is not known.Half Life
The elimination half-life of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) is not known.Clearance
The clearance of Chlordiazepoxide + Clidinium + Dicycloverine (or Dicyclomine) is not known.Here you find in details version of Neurospas Cd