Otorex
Otorex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Otorex is a brand name. Its generic name is Chlorbutol + Turpentine Oil + Benzocaine + Dichlorobenzene.
Introduction
Chlorbutol, Turpentine Oil, Benzocaine and Dichlorobenzene are commonly used ingredients in a variety of formulations, and are commonly found in products such as topical pain relievers, topical insecticides, inhaler decongestants, and varnishes.Uses
Chlorbutol is an antiseptic and anaesthetic agent that acts as a mild bronchodilator. Turpentine oil is a counterirritant that can reduce pain and inflammation when applied topically. Benzocaine is an anesthetic that provides temporary relief of pain. Dichlorobenzene is an insecticide which is used primarily as an insect repellent.Mechanism of Action
Chlorbutol works by inhibrating the growth of bacteria and fungi which reduces the risk of infection. Turpentine oil acts as a counterirritant, temporarily numbing the area and reducing swelling and pain. Benzocaine works by blocking nerve signals that send painful sensations, effectively numbing the area. Dichlorobenzene acts as an insecticide, repelling or killing insects that come in contact with it.How Long Does it Take to Work?
Chlorbutol begins to work almost immediately upon contact of skin and it can take a few minutes to take effect. Turpentine oil takes 5-10 minutes to work. Benzocaine takes up to 15 minutes to take effect and Dichlorobenzene begins working immediately.Absorption
Chlorbutol is readily absorbed through the skin and can be systemically absorbed via inhalation. Turpentine oil is readily absorbed through the skin. Benzocaine is well absorbed through the skin but is rapidly metabolized and excreted. Dichlorobenzene is readily absorbed through the skin and can be systemically absorbed through lungs.Route of Elimination
Chlorbutol is excreted in the urine and feces. Turpentine oil is rapidly metabolized and excreted in the urine and feces. Benzocaine is rapidly metabolized and excreted in the urine. Dichlorobenzene is rapidly metabolized and excreted in the urine and feces.Dosage
Chlorbutol is generally used at a dilution of 0.5 - 1%. Turpentine oil is generally used at a concentration of 0.08 - 0.12%. Benzocaine is generally applied at a concentration of 15-20%. Dichlorobenzene is generally used at a concentration of 0.03-0.05%.Administration
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene are generally applied topically as a cream, ointment, aerosol or liquid.Side Effects
Chlorbutol can cause skin irritation, contact dermatitis, burning sensation, and erythema. Turpentine oil can cause skin irritation, burning sensation, erythema, and contact dermatitis. Benzocaine can cause inflammation, contact dermatitis, allergic reactions and skin irritation. Dichlorobenzene can cause skin irritation, contact dermatitis, burning sensation and erythema.Toxicity
Chlorbutol is considered a low toxicity agent. Turpentine oil has low toxicity when used topically, however, long-term use can result in systemic toxicity. Benzocaine is associated with potential toxicity when used at high concentrations for a prolonged period of time. Dichlorobenzene is considered toxic if ingested.Precautions
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should be used with caution in individuals with a history of allergies or skin sensitivities. They should not be used near the eyes or mucous membranes, and should never be ingested.Interaction
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene may interact with other medications or substances, and should be used with caution in patients taking such medications or substances.Disease Interactions
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene are contraindicated in individuals who have an allergy or sensitivity to ingredients in the formulations.Drug Interactions
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene may interact with other medications, and should be used with caution in patients taking medications that may interact with them.Food Interactions
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene may interact with certain foods and beverages, and should be avoided while taking them.Pregnancy Use
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should be avoided in pregnant women as it can be absorbed systemically and may cause adverse effects.Lactation Use
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should be avoided in nursing mothers as it can be absorbed systemically and may cause adverse effects.Acute Overdose
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene in large doses can cause serious adverse effects. In the case of an acute overdose, it is important to seek medical attention immediately.Contraindication
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should not be used in patients with a known sensitivity or allergy to any of the ingredients in the formulations.Use Direction
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should be applied as per the instructions given by the physician or pharmacist and should not be used more than the recommended dosage or frequency.Storage Condition
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene should be stored in a cool, dry place away from direct sunlight. They should also be kept away from heat and moisture.Volume of Distribution
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene are poorly distributed throughout the body, and do not have a large volume of distribution.Half Life
Chlorbutol has a half-life of 2.7 hours. Turpentine oil has a half-life of 2.5 hours. Benzocaine has a half-life of 5.6 hours. Dichlorobenzene has a half-life of around 1 hour.Clearance
Chlorbutol, Turpentine oil, Benzocaine and Dichlorobenzene are rapidly eliminated from the body, and have a rapid clearance rate.Here you find in details version of Otorex