Methocarbamol

Methocarbamol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Methocarbamol is a brand name. Its generic name is Methocarbamol.

Introduction

Methocarbamol is a centrally-acting muscle relaxant. It exerts its effects by blocking the action of the neurotransmitter gamma-aminobutyric acid (GABA). By inhibiting GABA, Methocarbamol helps to reduce muscle spasms, which can improve movement, reduce pain, and improve physical function. It is generally used as a short-term treatment for acute muscle injuries such as back strain or strain due to a sports-related injury.

Uses for

Methocarbamol is used primarily for short-term relief of muscle spasms associated with the musculoskeletal system. It may also be used to reduce the pain associated with muscle spasms and to reduce inflammation. It is most commonly used to treat muscle spasms or strains in the back, neck, and shoulder muscles.

Mechanism of Action

Methocarbamol works by blocking the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that helps to regulate muscle activity. By blocking GABA, Methocarbamol helps to reduce muscle spasms, which can improve movement, reduce pain, and improve physical function.

How Long Does It Take To Work?

Methocarbamol generally begins to work within 1 to 2 hours of taking the medication. However, it may take a few days to a week before the full effect of the medication is realized, and the amount of time it takes to work may depend on the individual and the severity of the muscle spasm.

Absorption

Methocarbamol is readily absorbed after oral administration with peak plasma concentrations occurring within 2 hours. Subjects with severe renal failure, however, may experience prolonged absorption due to reduced renal function.

Route of Elimination

Methocarbamol is hepatobiliary eliminated. It is metabolized by the liver into active and inactive metabolites which are then eliminated via renal and fecal routes.

Dosage

The recommended dose of Methocarbamol for the relief of muscle spasms is 750-1500 mg four times a day. It is important to note that the maximum recommended daily dose is 6 g. Methocarbamol should not be taken for more than two or three weeks without consulting a physician, as it can cause serious side effects if taken for longer periods of time.

Administration

Methocarbamol should be taken orally as prescribed by a physician. It should be taken with or without food. Great care should be taken to follow the physician’s instructions on the proper use of Methocarbamol and to not exceed the daily recommended dose.

Side Effect

The most common side effects of Methocarbamol include drowsiness, dizziness, lightheadedness, nausea, vomiting, and headache. Other less common side effects include confusion, depression, agitation, tremor, loss of coordination, blurred vision, bad taste in the mouth, rash, and difficulty breathing. If any of these symptoms occur, it is important to stop taking the medication and contact a physician.

Toxicity

Overdose of Methocarbamol can cause serious side effects including slowed speech, confusion, slowed breathing, seizures, coma, and in rare cases, death. If you suspect an overdose, contact a poison control center or seek medical attention immediately.

Precaution

Methocarbamol should be used with caution in elderly patients and in those with kidney or liver impairment. It should also not be taken if you are pregnant or breastfeeding. In addition, it should not be taken if you have a pre-existing allergy to this medication or any of its ingredients.

Interaction

Methocarbamol can interact with other medications, including antidepressants, blood thinners, muscle relaxants, sleeping pills, and drugs used to treat seizures or anxiety. Before taking this medication, it is important to tell your doctor about any other medications you are taking.

Disease Interaction

Methocarbamol may interact with certain medical conditions such as liver or kidney impairment, myasthenia gravis, or asthma. Tell your doctor if you have any of these conditions before taking Methocarbamol.

Drug Interaction

Methocarbamol may interact with other medications, including antidepressants, blood thinners, muscle relaxants, sleeping pills, and drugs used to treat seizures or anxiety. Before taking this medication, it is important to tell your doctor about any other medications you are taking.

Food Interactions

Methocarbamol should not be taken with food as this can lessen the absorption rate of the medication. If taken with food, it is recommended to wait 2 hours before taking the medication.

Pregnancy Use

It is not recommended to take Methocarbamol during pregnancy. If you are pregnant or planning to become pregnant, contact your doctor about the potential risks of taking this medication.

Lactation Use

Methocarbamol is classified as a pregnancy Category C medication and should not be taken while breastfeeding. If you are breastfeeding, contact your doctor about the potential risks of taking this medication.

Acute Overdose

If an overdose of Methocarbamol is suspected, contact a poison control center or seek medical attention immediately. Symptoms of an overdose can include slowed speech, confusion, slowed breathing, seizures, and coma.

Contraindication

Methocarbamol should not be taken if you have a pre-existing allergy to this medication or any of its ingredients; blood or kidney disorders; myasthenia gravis; severe asthma; or a history of drug or alcohol abuse or drug dependence.

Use Direction

Methocarbamol should be taken as directed by a physician. Do not take more or less of the medication than prescribed and do not take it for more than two or three weeks without consulting a doctor. Take the medication at the same time every day and do not mix it with alcohol or other medications.

Storage Condition

Methocarbamol should be stored at room temperature, away from light and moisture, in an airtight container. It should be kept out of the reach of children and pets.

Volume of Distribution

The molecular weight of Methocarbamol is 177.25g/mol. The volume of distribution (Vd) is estimated to be 0.3L/kg. This means that the amount of drug in the body is equal to 0.3 times the body weight of the patient.

Half Life

The half-life of Methocarbamol is between 1.3 and 2.3 hours. This means the drug takes about 1.3 to 2.3 hours to reduce its concentration in the blood by half.

Clearance

The clearance of Methocarbamol is estimated to be around 6.8L/h/kg. This means that the body can remove 6.8L of the drug from the blood per hour for every kilogram of body weight.

Here you find in details version of Methocarbamol

Some Frequently Asked Questions About Methocarbamol

What is Methocarbamol?

Methocarbamol is a prescription muscle relaxant. It is used to treat skeletal muscle spasms and provide relief from discomfort associated with acute musculoskeletal conditions.

What is the generic name of Methocarbamol?

The generic name of Methocarbamol is Robaxin.

Is Methocarbamol a narcotic?

No, Methocarbamol is not a narcotic.

Is Methocarbamol habit forming?

No, Methocarbamol is not habit forming.

How often should I take Methocarbamol?

The recommended dosage of Methocarbamol is 500-750mg orally every 8 hours, up to a maximum of 4g per day.

What are the side effects of Methocarbamol?

Some common side effects of Methocarbamol include nausea, dizziness, headache, sedation, and increased urination. More serious side effects are rare but may include an allergic reaction, difficulty breathing, confusion, involuntary movements, and changes in vision.

What should I do if I miss a dose of Methocarbamol?

If you miss a dose of Methocarbamol, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule.

Does Methocarbamol interact with other drugs?

Yes, Methocarbamol may interact with other drugs, including antidepressants, anticonvulsants, antihistamines, narcotic pain relievers, sleeping pills, and certain muscle relaxants.

Can I take Methocarbamol while pregnant or breastfeeding?

Methocarbamol should only be used during pregnancy or while breastfeeding if clearly needed and if the potential benefits outweigh the risks. Always consult with your doctor before taking any medication while pregnant or breastfeeding.

Can I take Methocarbamol with alcohol?

It is not recommended to take Methocarbamol with alcohol because it may increase the risk of adverse effects such as drowsiness, dizziness, and impaired judgment.

Can I use Methocarbamol for muscle spasms?

Yes, Methocarbamol is commonly used to treat muscle spasms.

How long does Methocarbamol take to work?

Methocarbamol usually takes effect within 30 minutes of administration, but it may take up to 6 hours to reach its full effectiveness.

What is the usual dosage of Methocarbamol?

The usual adult dosage of Methocarbamol is 500mg to 750mg taken orally every 8 hours, up to a maximum of 4g per day.

Does Methocarbamol have any special instructions?

Yes, Methocarbamol should be taken with food or a full glass of water to prevent stomach upset. It is important to take Methocarbamol exactly as prescribed by your doctor.

Does Methocarbamol treat inflammation?

No, Methocarbamol does not treat inflammation. It is used to treat muscle spasms, and it can provide relief from discomfort associated with acute musculoskeletal conditions.

What are the contraindications for Methocarbamol?

Methocarbamol is contraindicated in people with a history of seizures, liver or kidney disease, porphyria, and in those taking monoamine oxidase inhibitors (MAOIs). It should not be used in children under the age of 12. It should also not be used in people with a history of allergic reactions to methocarbamol or other muscle relaxant medications.

Can I take Methocarbamol with ibuprofen?

It is not recommended to take Methocarbamol with ibuprofen due to the potential for increased side effects such as nausea, dizziness, and drowsiness.

Can I drive after taking Methocarbamol?

No, you should not drive after taking Methocarbamol because it can cause drowsiness and impair judgment, reaction time, and coordination.

Is Methocarbamol a prescription drug?

Yes, Methocarbamol is a prescription drug.

Can I take Methocarbamol with aspirin?

Yes, it is generally safe to take Methocarbamol with aspirin.

Can I take Methocarbamol with tylenol?

Yes, it is generally safe to take Methocarbamol with tylenol.

What is the shelf life of Methocarbamol?

The shelf life of Methocarbamol is 36 months when stored at room temperature.

Can I take Methocarbamol with food?

Yes, it is recommended to take Methocarbamol with food or a full glass of water to reduce the risk of stomach upset.

Can I take Methocarbamol with Advil?

It is not recommended to take Methocarbamol with Advil due to the potential for increased side effects such as nausea, dizziness, and drowsiness.

Is Methocarbamol the same as Robaxin?

Yes, Methocarbamol is the generic name of the brand name drug Robaxin.

How long can I take Methocarbamol?

Methocarbamol should only be taken for a short period of time, usually 2-3 weeks, and only as directed by your doctor.

What are the common side effects of taking Methocarbamol?

Common side effects of taking Methocarbamol include nausea, dizziness, headache, sedation, and increased urination.

Can I take Methocarbamol with anticonvulsants?

It is not recommended to take Methocarbamol with anticonvulsants due to the potential for increased side effects.

Can I take Methocarbamol with antihistamines?

It is not recommended to take Methocarbamol with antihistamines due to the potential for increased side effects.

What should I do if I experience any serious side effects while taking Methocarbamol?

You should seek immediate medical attention if you experience any serious side effects while taking Methocarbamol, such as difficulty breathing, confusion, involuntary movements, or changes in vision.

Can I take Methocarbamol with corticosteroids?

Yes, it is generally safe to take Methocarbamol with corticosteroids. However, consult with your doctor before taking any medication with Methocarbamol.

Can I take Methocarbamol with sleeping pills?

It is not recommended to take Methocarbamol with sleeping pills, as it may increase the risk of serious side effects such as confusion, sedation, and impaired judgment.

What is the recommended dosage of Methocarbamol?

The recommended dosage of Methocarbamol is 500-750mg orally every 8 hours, up to a maximum of 4g per day.

Does Methocarbamol have to be taken with food or water?

It is recommended to take Methocarbamol with food or a full glass of water to reduce the risk of stomach upset.

Can elderly people take Methocarbamol?

Yes, elderly people can take Methocarbamol as long as it is prescribed by a doctor and taken according to the prescribed instructions.

Is Methocarbamol a controlled substance?

No, Methocarbamol is not a controlled substance.

Should Methocarbamol be taken at the same time every day?

It is not necessary to take Methocarbamol at the same time every day, but it should be taken according to the instructions provided by your doctor.

Can I take Methocarbamol with acetaminophen?

Yes, it is generally safe to take Methocarbamol with acetaminophen.

Does Methocarbamol have any reported interactions with dietary supplements?

Yes, Methocarbamol may interact with certain dietary supplements. Always consult with your doctor before taking any medications or supplements with Methocarbamol.

Can I take Methocarbamol with muscle relaxants?

It is not recommended to take Methocarbamol with other muscle relaxants due to the potential for increased side effects.

Does Methocarbamol cause weight gain?

Weight gain is not a common side effect of Methocarbamol, but it is possible.

Does Methocarbamol cause drowsiness?

Yes, Methocarbamol can cause drowsiness and should not be taken before driving or operating machinery.

Can I take Methocarbamol with ibuprofen or aspirin?

It is not recommended to take Methocarbamol with ibuprofen or aspirin due to the potential for increased side effects such as nausea, dizziness, and drowsiness.

Do I need to avoid certain activities while taking Methocarbamol?

You should avoid activities that require alertness such as driving or operating machinery while taking Methocarbamol.

Are there any conditions that should prevent me from taking Methocarbamol?

Yes, you should not take Methocarbamol if you have a history of seizures, liver or kidney disease, porphyria, or if you are taking monoamine oxidase inhibitors (MAOIs).