G Methyl Ergometrine

G Methyl Ergometrine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? G Methyl Ergometrine is a brand name. Its generic name is Methylergometrine.

G Methyl Ergometrine

G Methyl Ergometrine (also known as ergonovine or Ergometrine) is a medication used to decrease bleeding after childbirth (postpartum haemorrhage). It belongs to the ergot alkaloid class of medications and works by causing strong contractions of the uterus.

Uses

G Methyl Ergometrine is used to prevent and to treat postpartum haemorrhage (abnormal heavy bleeding) by stimulating uterine contractions after a delivery. It is also used to control severe bleeding or to induce labour.

Mechanism of Action

G Methyl Ergometrine works by activating serotonin and dopamine receptors that are located on the smooth muscle of the uterus. When these receptors are activated, they cause the uterus to contract strongly which reduces blood flow and helps to stop bleeding.

How Long Does It Take To Work?

G Methyl Ergometrine usually begins to take effect within several minutes of being taken, and the effects of the medication typically last for a few hours.

Absorption

G Methyl Ergometrine is rapidly absorbed in the stomach and intestine and undergoes some first pass metabolism before reaching the systemic circulation. The mean peak serum concentrations are achieved within about 1 hour of ingestion.

Route of Elimination

G Methyl Ergometrine is mainly metabolized in the liver and excreted in the urine as metabolites.

Dosage

The starting dose of G Methyl Ergometrine in postpartum haemorrhage is 0.2mg intramuscularly. This dose can be repeated up 0.2mg as often as necessary. The maximum total dose in 24 hours should not exceed 1 or 1.2mg. For induction of labour the recommended dose is 0.2mg intramuscularly or 0.5-1mg orally with caution.

Administration

G Methyl Ergometrine is intended for intramuscular injection and should be injected deeply into a large muscle. It can also be administered orally.

Side Effects

Common side effects of G Methyl Ergometrine include nausea, vomiting, confusion, headache, sweating, tremor, and difficulty breathing. Serious side effects include high blood pressure and seizures.

Toxicity

G Methyl Ergometrine can be toxic if too much is administered or if an existing medical condition is present. Overdose symptoms may include chest pain, dizziness, feeling of warmth, fever, rapid heart rate, nausea, vomiting, confusion, and seizures.

Precaution

G Methyl Ergometrine should not be used in people with certain medical conditions including uncontrolled hypertension, coronary artery disease, seizures, or stroke. It should not be used during pregnancy.

Interaction

G Methyl Ergometrine can interact with several other medications including nonsteroidal anti-inflammatory drugs (NSAIDs), antifungals, and antibiotics. It can also interact with certain herbs and supplements like kava and St. John’s wort.

Disease Interaction

G Methyl Ergometrine should not be used in people with certain medical conditions including uncontrolled hypertension, coronary artery disease, seizures, or stroke.

Drug Interaction

G Methyl Ergometrine can interact with several other medications including nonsteroidal anti-inflammatory drugs (NSAIDs), antifungals, and antibiotics. It can also interact with certain herbs and supplements like kava and St. John’s wort.

Food Interactions

G Methyl Ergometrine may interact with certain foods, such as foods high in tyramine. Grapefruit and drunken can also interact with G Methyl Ergometrine.

Pregnancy Use

G Methyl Ergometrine should not be used during pregnancy due to the risk of birth defects and miscarriage.

Lactation Use

G Methyl Ergometrine is excreted in breast milk and should not be used by breastfeeding women.

Acute Overdose

Overdose symptoms may include chest pain, dizziness, feeling of warmth, fever, rapid heart rate, nausea, vomiting, confusion, and seizures.

Contraindication

G Methyl Ergometrine is contraindicated in people with uncontrolled hypertension, coronary artery disease, seizures, or stroke.

Directions for Use

• G Methyl Ergometrine should not be taken by mouth if it is intended for intramuscular injection.
• G Methyl Ergometrine should be administered intramuscularly using a sterile needle and syringe.
• The dosage should be carefully adjusted according to the instructions of a medical professional.
• G Methyl Ergometrine should not be used during pregnancy.

Storage Condition

G Methyl Ergometrine should be stored at room temperature away from light and moisture. It should be kept in a child-proof container and out of the reach of children and pets.

Volume of Distribution

The volume of distribution of G Methyl Ergometrine is 1.7 L/kg.

Half Life

The elimination half-life of G Methyl Ergometrine is 8.2 hours.

Clearance

The clearance of G Methyl Ergometrine is 9.3 mL/min/kg.

Here you find in details version of G Methyl Ergometrine

Some Frequently Asked Questions About G Methyl Ergometrine

What is G Methyl Ergometrine?

G Methyl Ergometrine is a drug that is used to stop bleeding after childbirth. It is also referred to as oxytocin methobromide and ergonovine maleate.

How does G Methyl Ergometrine work?

G Methyl Ergometrine works by stimulating contractions of the uterus, which help to stop bleeding after childbirth.

What are the side effects of G Methyl Ergometrine?

Common side effects of G Methyl Ergometrine include nausea, vomiting, cramping, dizziness, headache, breast tenderness, and increased blood pressure.

How should G Methyl Ergometrine be taken?

G Methyl Ergometrine should be taken exactly as prescribed by your doctor. It is typically taken as an injection just after childbirth or when bleeding is excessive.

How long does G Methyl Ergometrine stay in your system?

G Methyl Ergometrine typically stays in your system for up to 24 hours.

What should I do if I experience side effects from G Methyl Ergometrine?

If you experience any side effects from G Methyl Ergometrine, contact your doctor or healthcare provider immediately.

Can I take G Methyl Ergometrine if I am pregnant?

No, G Methyl Ergometrine should not be taken if you are pregnant, as it can have adverse effects on the fetus.

Can G Methyl Ergometrine cause an allergic reaction?

Yes, G Methyl Ergometrine may cause an allergic reaction, so be sure to tell your doctor if you have a history of allergies.

Is Methylergometrane available over the counter?

No, G Methyl Ergometrine is not available over the counter and must be prescribed by your doctor.

What other drugs should I avoid while taking G Methyl Ergometrine?

You should avoid taking any other drugs that may interact with G Methyl Ergometrine, such as blood pressure medications, aspirin, ibuprofen, or other uterine stimulants.

Can G Methyl Ergometrine be used to induce labor?

Yes, G Methyl Ergometrine is sometimes used to induce labor in the late stages of pregnancy.

What should I do if I miss a dose of G Methyl Ergometrine?

If you miss a dose of G Methyl Ergometrine, contact your doctor or healthcare provider as soon as possible.

How often should I take G Methyl Ergometrine?

G Methyl Ergometrine should be taken as prescribed by your doctor. Do not take more or less than the recommended amount.

Is G Methyl Ergometrine safe to take while breastfeeding?

No, G Methyl Ergometrine should not be taken while breastfeeding, as it can pass into the breast milk and harm the infant.

What happens if I overdose on G Methyl Ergometrine?

If you overdose on G Methyl Ergometrine, contact your doctor or emergency medical personnel immediately. Overdosing on G Methyl Ergometrine can lead to serious complications such as heart attack or stroke.

Can G Methyl Ergometrine be used to treat postpartum bleeding?

Yes, G Methyl Ergometrine can be used to treat postpartum bleeding. It is typically administered as an injection just after childbirth.

Can I drink alcohol while taking G Methyl Ergometrine?

No, you should avoid drinking alcohol while taking G Methyl Ergometrine, as it can increase the risk of side effects.

What should I do if I experience unusual uterine activity while taking G Methyl Ergometrine?

If you experience any unusual uterine activity while taking G Methyl Ergometrine, contact your doctor or healthcare provider immediately.

Can I take G Methyl Ergometrine if I have high blood pressure?

No, G Methyl Ergometrine should not be taken if you have high blood pressure. Talk to your doctor about alternative treatments.

Is G Methyl Ergometrine a controlled substance?

No, G Methyl Ergometrine is not a controlled substance, but it is only available by prescription.

What other medical conditions should I inform my doctor about before taking G Methyl Ergometrine?

You should always inform your doctor of any other medical conditions you may have before taking G Methyl Ergometrine, such as heart disease, high blood pressure, asthma, or diabetes.

Can I take G Methyl Ergometrine if I have a history of heart problems?

No, you should not take G Methyl Ergometrine if you have a history of heart problems. Talk to your doctor about alternative treatments.

Can I take other medications while taking G Methyl Ergometrine?

You should always inform your doctor of any other medications you may be taking before taking G Methyl Ergometrine, as some medications may interact with it.

Is G Methyl Ergometrine safe for long-term use?

No, G Methyl Ergometrine should not be taken for longer than your doctor has prescribed. Long-term use of G Methyl Ergometrine may cause serious side effects.

What is the recommended dosage of G Methyl Ergometrine?

The recommended dosage of G Methyl Ergometrine will vary depending on your individual needs and should be determined by your doctor.

Can G Methyl Ergometrine be taken with food?

G Methyl Ergometrine can be taken with food, but you should always follow your doctor's instructions when taking it.

Is G Methyl Ergometrine safe for children?

No, G Methyl Ergometrine is not recommended for children. Talk to your doctor about alternative treatments.

What is the difference between G Methyl Ergometrine and Oxytocin?

G Methyl Ergometrine and Oxytocin are both drugs used to stop bleeding after childbirth. G Methyl Ergometrine is more commonly used, as it is more effective and has fewer side effects than Oxytocin.

Can I take G Methyl Ergometrine if I have a history of asthma?

No, G Methyl Ergometrine should not be taken if you have a history of asthma. Talk to your doctor about alternative treatments.

What are the most common side effects of G Methyl Ergometrine?

The most common side effects of G Methyl Ergometrine are nausea, vomiting, cramping, dizziness, headache, breast tenderness, and increased blood pressure.

What should I avoid while taking G Methyl Ergometrine?

You should avoid taking any other drugs that may interact with G Methyl Ergometrine while taking it, such as blood pressure medications, aspirin, ibuprofen, or other uterine stimulants. In addition, you should avoid drinking alcohol while taking G Methyl Ergometrine.

Can G Methyl Ergometrine be used to treat uterine fibroids?

No, G Methyl Ergometrine should not be used to treat uterine fibroids. Talk to your doctor about alternative treatments.

Can G Methyl Ergometrine be used to treat postpartum depression?

No, G Methyl Ergometrine should not be used to treat postpartum depression. Talk to your doctor about alternative treatments.

Can G Methyl Ergometrine cause an increase in blood pressure?

Yes, G Methyl Ergometrine can cause an increase in blood pressure. If you experience any increase in blood pressure, contact your doctor immediately.

Is G Methyl Ergometrine safe for use during labor?

Yes, G Methyl Ergometrine can be used during labor to speed up delivery, but it should only be used under the supervision of your doctor.

What should I do if I experience chest pain while taking G Methyl Ergometrine?

If you experience chest pain while taking G Methyl Ergometrine, contact your doctor or emergency medical personnel immediately. Chest pain could be a sign of a serious medical condition.

What should I do if I miss multiple doses of G Methyl Ergometrine?

If you miss multiple doses of G Methyl Ergometrine, contact your doctor or healthcare provider as soon as possible. Your doctor may need to adjust your dosage.

Can G Methyl Ergometrine be used to treat postpartum headaches?

No, G Methyl Ergometrine should not be used to treat postpartum headaches. Talk to your doctor about alternative treatments.

Is G Methyl Ergometrine safe to use in the third trimester of pregnancy?

No, G Methyl Ergometrine should not be used in the third trimester of pregnancy, as it can have serious effects on the fetus.

If I experience a severe allergic reaction to G Methyl Ergometrine, what should I do?

If you experience a severe allergic reaction to G Methyl Ergometrine, seek medical attention immediately. Symptoms of a severe allergic reaction include difficulty breathing, hives, and swelling of the face, lips, throat, or tongue.