Gliclazidum
Gliclazidum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gliclazidum is a brand name. Its generic name is Gliclazide.
Introduction
Gliclazidum (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Gliclazidum is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Gliclazidum works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Gliclazidum is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Gliclazidum is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Gliclazidum should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Gliclazidum can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Gliclazidum is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Gliclazidum can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Gliclazidum can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Gliclazidum may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Gliclazidum may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Gliclazidum can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Gliclazidum should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Gliclazidum should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Gliclazidum should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Gliclazidum should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Gliclazidum
Some Frequently Asked Questions About Gliclazidum
What is Gliclazidum?
Gliclazidum is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Gliclazidum work?
Gliclazidum works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Gliclazidum?
Gliclazidum is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Gliclazidum?
Gliclazidum may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Gliclazidum cause hypoglycemia?
Yes, Gliclazidum can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Gliclazidum be taken?
Gliclazidum should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Gliclazidum to work?
Gliclazidum usually starts to work within 1-2 hours after it is taken.
Does Gliclazidum need to be taken with food?
No, Gliclazidum does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Gliclazidum?
The recommended dose of Gliclazidum depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Gliclazidum?
If you forget to take Gliclazidum, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Gliclazidum?
Yes, it is recommended to avoid alcohol while taking Gliclazidum as it can increase the risk of adverse effects such as low blood sugar.
Can Gliclazidum be taken while pregnant or breastfeeding?
Gliclazidum should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Gliclazidum?
It is important to follow a healthy and balanced diet while taking Gliclazidum. Avoid foods high in sugar, fat, and cholesterol.
Is Gliclazidum available as a generic medication?
Yes, Gliclazidum is available as a generic medication.
What other medications should not be taken with Gliclazidum?
Certain medications can interact with Gliclazidum and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Gliclazidum with metformin?
Yes, Gliclazidum can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Gliclazidum?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Gliclazidum be used to treat type 1 diabetes?
No, Gliclazidum is not suitable for use in people with type 1 diabetes.
Does Gliclazidum cause weight gain?
Gliclazidum can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Gliclazidum?
If you experience side effects while taking Gliclazidum, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Gliclazidum?
Yes, diabetic ketoacidosis can occur while taking Gliclazidum. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Gliclazidum be stored?
Gliclazidum should be stored at room temperature away from direct sunlight and heat. Do not keep Gliclazidum in the refrigerator or freezer.
Can I overdose on Gliclazidum?
Yes, it is possible to overdose on Gliclazidum. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Gliclazidum?
No, it is recommended that you do not donate blood while taking Gliclazidum.
Can I take Gliclazidum if I have kidney disease?
It is recommended that you speak to your doctor before taking Gliclazidum if you have kidney disease. Your doctor may recommend a different medication.
Is Gliclazidum a blood thinner?
No, Gliclazidum is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Gliclazidum be used to treat Type 1 diabetes?
No, Gliclazidum is not suitable for use in people with Type 1 diabetes.
Can Gliclazidum cause low blood pressure?
Yes, Gliclazidum can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Gliclazidum while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Gliclazidum. Certain medications can interact with Gliclazidum.
Does Gliclazidum raise cholesterol levels?
Yes, Gliclazidum can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Gliclazidum a steroid?
No, Gliclazidum is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Gliclazidum cause diarrhea?
Yes, Gliclazidum can cause diarrhea. If you experience diarrhea while taking Gliclazidum, speak to your doctor or pharmacist.
Can I take Gliclazidum with ibuprofen?
It is recommended that you do not take Gliclazidum with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Gliclazidum with muscle relaxers?
It is recommended that you do not take Gliclazidum with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Gliclazidum?
If you miss a dose of Gliclazidum, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Gliclazidum while breastfeeding?
No, it is recommended that you do not take Gliclazidum while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Gliclazidum while pregnant?
No, it is recommended that you do not take Gliclazidum while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Gliclazidum cause headaches?
Yes, Gliclazidum can cause headaches in some people. If you experience headaches while taking Gliclazidum, speak to your doctor or pharmacist.
Can I take Gliclazidum with other diabetes medications?
Yes, Gliclazidum can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Gliclazidum?
If you experience low blood sugar while taking Gliclazidum, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Gliclazidum?
It is important to follow a healthy and balanced diet while taking Gliclazidum. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Gliclazidum for?
The length of time that you take Gliclazidum for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Gliclazidum a controlled substance?
No, Gliclazidum is not a controlled substance.