Doxazosin
Doxazosin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Doxazosin is a brand name. Its generic name is Doxazosin.
Introduction
Doxazosin is a prescription medication used in the treatment of high blood pressure and benign prostatic hyperplasia (BPH). It is a quinazoline derivative which belongs to a group of drugs known as alpha-blockers. By blocking the action of certain chemicals in the body, Doxazosin helps to relax the blood vessels, allowing the heart to beat more slowly and easily.Uses For
Doxazosin is used to treat hypertension (high blood pressure) in adults and benign prostatic hyperplasia (BPH) in men with an enlarged prostate. It can also be used to decrease the risk of disability or death due to recurrent heart attacks in people with stable coronary artery disease.Mechanism of Action
Doxazosin acts by blocking the action of certain chemicals in the body that cause the blood vessels to narrow (constrict). This helps to relax the blood vessels, allowing the heart to beat more slowly and easily.How Long Does it Take to Work?
It may take two to four weeks for the full effects of Doxazosin to be realized. It is important to continue taking the medication even if you do not feel any difference in your health. If you have not seen any improvement after two to four weeks, contact your doctor to discuss other possible treatments.Absorption
Doxazosin is rapidly absorbed from the gastrointestinal tract following oral administration. The absorption of doxazosin is not affected by food.Route of Elimination
Doxazosin is eliminated primarily through the kidneys.Dosage
For hypertension: adults—1 to 8 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 8 mg per day. For benign prostatic hyperplasia (BPH): adults—1 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 4 mg per day.Administration
Doxazosin must be taken exactly as prescribed by your doctor to achieve the best results. The tablet should be swallowed whole with a full glass of water. The tablets should not be chewed, crushed, or divided.Side Effects
The most common side effects of doxazosin may include dizziness, headache, tiredness, nausea, and increased urination. However, since everyone is different, other side effects may also occur.Toxicity
Doxazosin is considered to be a low toxicity medication. In cases of overdose, seek medical attention immediately.Precaution
People with heart disease, liver disease, kidney disease, or diabetes should discuss with their doctor before taking doxazosin.Interaction
Certain medications, such as aspirin, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain types of cholesterol-lowering medications (statins) may interact with Doxazosin. It is important to tell your doctor about all the medications you are taking, including over the counter drugs, vitamins, and herbal supplements.Disease Interaction
Doxazosin may interact with other diseases such as kidney or liver disease, heart failure, and diabetes.Drug Interaction
Certain medications such as aspirin, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain types of cholesterol-lowering medications (statins) may interact with doxazosin and should be avoided or used with caution. Tell your doctor about all the medications you are taking.Food Interactions
Doxazosin is not affected by food.Pregnancy Use
Doxazosin should not be used during pregnancy, unless clearly needed. Tell your doctor if you are pregnant or planning to become pregnant.Lactation Use
It is not known if doxazosin passes into breast milk. Tell your doctor if you are breastfeeding or planning to breastfeed.Acute Overdose
In cases of overdose, seek medical attention immediately.Contraindication
Doxazosin should not be used in people who are allergic to it or any of its ingredients.Use Direction
Doxazosin should be taken exactly as prescribed by your doctor. The tablet should be swallowed whole with a full glass of water. The tablets should not be chewed, crushed, or divided. Take the missed dose as soon as you remember.Storage Condition
Store at room temperature away from moisture and heat.Volume of Distribution
Doxazosin has a volume of distribution of 2.3 L/kg.Half Life
The half life of doxazosin is 10-15 hours.Clearance
The clearance of doxazosin is 14 L/h.Here you find in details version of Doxazosin
Some Frequently Asked Questions About Doxazosin
What is doxazosin?
Doxazosin is a type of medication known as an alpha-blocker. It works by blocking certain chemicals in the body that can cause blood vessels to tighten. This helps to relax the blood vessels and improve blood flow.
What is doxazosin used for?
Doxazosin is typically used for the treatment of high blood pressure, or hypertension. It may also be used to treat other conditions as determined by your doctor.
Is doxazosin a generic drug?
Yes, doxazosin is available as both a branded drug and a generic drug.
How should I take doxazosin?
Take doxazosin exactly as directed by your doctor. The dosage and how often you take the medication will depend on your individual condition and medical history. Do not take more or less than prescribed, and do not stop taking doxazosin without first talking to your doctor.
How long does it take for doxazosin to work?
It usually takes about 2 - 4 weeks for the full effects of doxazosin to be seen. However, some people may see a benefit sooner. It is important to take doxazosin as prescribed to get the most benefit.
What are the side effects of doxazosin?
Common side effects of doxazosin include lightheadedness, dizziness, headache, nausea, and fatigue. If you experience any of these side effects, contact your doctor. Serious side effects are rare, but may include abnormal heart rhythm, chest pain, and difficulty breathing.
Can doxazosin cause weight gain?
Weight gain is not a common side effect of doxazosin. However, if you experience unexplained weight gain while taking doxazosin, contact your doctor.
Are there any drug interactions I should be aware of with doxazosin?
Yes, there are several drug interactions to be aware of when taking doxazosin. Make sure your doctor is aware of all other medications you are taking before starting doxazosin. This includes prescription and nonprescription medications, dietary supplements, and herbal remedies.
Are there any special precautions to take with doxazosin?
Yes, you should not take doxazosin if you are pregnant or breastfeeding. You should also inform your doctor if you have any liver or kidney problems, as well as any blood vessel problems, such as congestive heart failure or uncontrolled high blood pressure.
Can I drink alcohol while taking doxazosin?
No, it is not recommended to drink alcohol while taking doxazosin. Alcohol can increase the side effects of doxazosin, including dizziness and lightheadedness. You should also limit caffeine intake (coffee, tea, soft drinks) when taking doxazosin as this can worsen the side effects.
What should I do if I miss a dose of doxazosin?
If you miss a dose of doxazosin, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed dose.
What should I do if I overdose on doxazosin?
If you overdose on doxazosin, seek immediate medical attention or call 911. Symptoms of a doxazosin overdose can include drowsiness, dizziness, and difficulty breathing.
Can doxazosin be used in children?
No, doxazosin is not approved for use in children and should not be used in this age group.
How long does doxazosin stay in the body?
It typically takes about 4 - 6 hours for doxazosin to be eliminated from the body. However, this can vary depending on factors such as body weight, kidney function, and other medications being taken.
How long should I take doxazosin?
You should take doxazosin for as long as prescribed by your doctor. Do not stop taking doxazosin without consulting your doctor first, as this can worsen your condition.
Can I take doxazosin while pregnant?
No, doxazosin is not recommended for use during pregnancy. If you are pregnant or planning on becoming pregnant while taking doxazosin, speak to your doctor about the risks and benefits.
Should I take doxazosin with food?
Your doctor may tell you to take doxazosin with food to reduce stomach upset. You should follow your doctor’s instructions for taking doxazosin.
Can doxazosin cause hair loss?
No, hair loss is not a common side effect of doxazosin. However, if you experience any unusual side effects while taking doxazosin, contact your doctor.
Is doxazosin a diuretic?
No, doxazosin is not a diuretic. It is a type of medication known as an alpha-blocker.
Can doxazosin be used for prostate problems?
Yes, doxazosin is often used to treat benign prostatic hyperplasia (BPH) or an enlarged prostate. It works to relax the muscles in the prostate and bladder in order to reduce symptoms associated with BPH.
Are there any dietary restrictions I should be aware of when taking doxazosin?
You do not need to make any specific dietary changes while taking doxazosin. However, you may wish to make changes to your overall diet in order to reduce your risk of heart and other vascular diseases.
What should I do if I have an allergic reaction to doxazosin?
If you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, or tongue, seek medical attention immediately. You should also stop taking doxazosin and speak to your doctor about alternatives.
Is doxazosin an controlled substance?
No, doxazosin is not classified as a controlled substance.
Can doxazosin be used to treat high cholesterol?
No, doxazosin is not typically used to treat high cholesterol. However, your doctor may prescribe it in combination with other cholesterol-lowering medications.
Can doxazosin be used to treat an enlarged heart?
Yes, doxazosin may be used to treat an enlarged heart (or cardiomyopathy). It works by helping to lower blood pressure and improve blood flow throughout the body.
Will doxazosin lower my heart rate?
Yes, doxazosin may lower your heart rate by blocking certain chemicals in the body. This helps to relax the blood vessels and improve blood flow, resulting in a lower heart rate.
Does doxazosin worsen erectile dysfunction?
No, doxazosin does not generally worsen erectile dysfunction. In fact, it may help to improve erectile dysfunction by lowering blood pressure and improving blood flow to the penis.
Can doxazosin cause blurred vision?
Yes, blurred vision is a possible side effect of doxazosin. If you experience blurred vision, stop taking doxazosin and contact your doctor.
Can doxazosin cause dry mouth?
Yes, dry mouth is a common side effect of doxazosin. If this becomes a problem, you may need to increase your fluid intake.
Does doxazosin raise potassium levels?
No, doxazosin does not typically raise potassium levels. However, it is important to check your potassium levels regularly as it can interact with other medications.
Can doxazosin cause headaches?
Yes, headaches are a common side effect of doxazosin. If the headaches become frequent or severe, contact your doctor.
Is doxazosin a beta blocker?
No, doxazosin is not a beta blocker. It is a type of medication known as an alpha-blocker.
Can doxazosin cause insomnia?
Insomnia is not a common side effect of doxazosin. However, if you experience insomnia while taking doxazosin, contact your doctor.
Should I take doxazosin in the morning or evening?
Your doctor may recommend taking doxazosin in the morning or evening depending on your individual needs. However, you should take it at the same time each day to maintain an even level of the medication in your system.
Can doxazosin cause constipation?
Yes, constipation is a possible side effect of doxazosin. If this occurs, make sure to increase your fiber and fluid intake.
Can doxazosin be used to treat heart failure?
Yes, doxazosin may be used to treat certain types of heart failure. It works by helping to lower blood pressure and improve blood flow.
Is doxazosin a blood thinner?
No, doxazosin is not a blood thinner. It is a type of medication known as an alpha-blocker.
Can doxazosin be used to treat sleep apnea?
No, doxazosin is not typically used to treat sleep apnea. However, it may be used in combination with other medications to treat certain types of sleep apnea.
Can doxazosin be used to treat hypertension?
Yes, doxazosin is often used to treat hypertension, or high blood pressure. It works by blocking certain chemicals in the body that can cause the blood vessels to tighten.
Can doxazosin cause blurred vision?
Yes, blurred vision is a possible side effect of doxazosin. If you experience blurred vision, stop taking doxazosin and contact your doctor.
Should I take doxazosin with or without food?
Your doctor may tell you to take doxazosin with food to reduce stomach upset. You should follow your doctor’s instructions for taking doxazosin.
Can doxazosin be used to treat arrhythmia?
Yes, doxazosin may be used to treat certain types of arrhythmias. It works by blocking certain chemicals in the body that can cause the heart rate to become irregular.
Does doxazosin interact with grapefruit juice?
Yes, grapefruit juice may interact with doxazosin and increase the risk of side effects. It is best to avoid taking doxazosin with grapefruit juice.