Cefuroximum

Cefuroximum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefuroximum is a brand name. Its generic name is Cefuroxime.

Introduction

Cefuroximum is an antibiotic of the cephalosporin class used to treat a variety of bacterial infections. It can be used to treat a wide range of infections including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Uses For

Cefuroximum is used to treat a variety of bacterial infections, including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Mechanism of Action

Cefuroximum works by inhibiting the growth of bacteria by interfering with the bacterial cell wall synthesis. This prevents the bacteria from being able to replicate and leads to the eventual death of the bacteria.

How Long Does It Take To Work?

Cefuroximum typically begins to work within 48 hours of taking it, and symptoms should improve during that time. It is important to finish the full course of medication to prevent the re-emergence of the infection. If symptoms have not improved after 48 hours, contact your doctor.

Absorption

Cefuroximum is absorbed rapidly from the gastrointestinal tract and reaches peak concentrations in various organs and tissues, including the lungs, kidneys, prostate , and central nervous system.

Route of Elimination

Cefuroximum is eliminated mainly via the kidneys. It is also metabolized in the liver and excreted in the bile.

Dosage

The dosage of cefuroxime varies according to the infection being treated and the patient's age and weight. Generally, it is given as a single dose or in two divided doses given every 12 hours. For adults, the dosage ranges from 125 mg to 500 mg taken orally every 8 to 12 hours. For children, the dosage may be lower. It is important to follow your doctor's instructions.

Administration

Cefuroximum is usually taken orally. It can also be given intravenously, depending on the condition being treated. For oral administration, it is usually taken with a full glass of water. It can be taken with or without food.

Side Effect

Common side effects associated with cefuroxime include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, itching, and vaginal itching and discharge.

Toxicity

Cefuroximum is generally safe and well tolerable at recommended doses. However, it can cause certain toxic side effects when taken in high doses, including seizures, tremors, coma, and death.

Precautions

Cefuroximum should not be used in patients with a known allergy or hypersensitivity to cefuroxime, other cephalosporins, or penicillins. Cefuroximum should be used with caution in patients with a history of liver or kidney disease, or in those who are pregnant or breastfeeding.

Interaction

Cefuroximum can interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, warfarin (blood thinners), and certain antibiotics. Before taking cefuroxime, it is important to tell your doctor about any other medications you are taking to avoid potential interactions.

Disease Interactions

Cefuroximum can interact with certain diseases that can affect its efficacy. These include certain liver and kidney disease, diseases of the immune system, and conditions that affect the gastrointestinal tract. It is important to tell your doctor if you have any of these conditions before taking cefuroxime.

Drug Interactions

Cefuroximum can interact with certain medications, including other antibiotics, anticoagulants (blood thinners), nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and probenecid. It is important to tell your doctor about all medications you are taking.

Food Interactions

Cefuroximum may interact with certain foods. It should be taken at least two hours before or after taking calcium, magnesium, or iron supplements or antacids. Also, avoid alcohol while taking cefuroxime.

Pregnancy Use

Cefuroximum is generally safe to use during pregnancy, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime during pregnancy.

Lactation Use

Cefuroximum is usually safe to use during lactation, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime while breastfeeding.

Acute Overdose

An overdose of cefuroxime can cause serious side effects, including convulsions, dizziness, loss of consciousness, and even coma in some cases. It is important to seek medical attention immediately if you think you or someone else has taken an overdose of cefuroxime.

Contraindication

Cefuroximum is not to be used in patients with a known allergy or hypersensitivity to cefuroxime or other cephalosporins, or penicillins. Cefuroximum should also not be used in patients with a history of liver or kidney disease.

Use Direction

Cefuroximum should be taken as directed by your doctor. The dosage and frequency should not be exceeded or decreased without consulting your doctor. Taking cefuroxime with food or antacids can help reduce side effects.

Storage Condition

Cefuroximum should be stored at room temperature, below 30°C (86°F). Keep it in a tightly closed container away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of cefuroxime is about 0.4-0.5 L/Kg.

Half Life

Cefuroximum has a half-life of 2-3 hours.

Clearance

Cefuroximum is cleared from the body by both hepatic and renal pathways. The total clearance is 6.3 mL/min/kg.

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Some Frequently Asked Questions About Cefuroximum

What is Cefuroximum?

Cefuroximum is an antibiotic used to treat a wide variety of infections caused by bacteria. It works by stopping the growth of bacteria. It is available in brand and generic form.

What is Cefuroximum used to treat?

Cefuroximum is indicated to treat bacterial infections, including upper and lower respiratory tract, urinary tract, skin, and soft tissue infections.

Does Cefuroximum have side effects?

Cefuroximum may cause side effects such as nausea, vomiting, diarrhea, headache, or dizziness.

Can Cefuroximum be used to treat bronchitis?

Yes, Cefuroximum is commonly used to treat infections caused by bronchitis.

Is Cefuroximum a penicillin drug?

No, Cefuroximum is not a penicillin drug. It is a cephalosporin antibiotic.

Is Cefuroximum safe to use during pregnancy?

Cefuroximum is generally considered safe to use during pregnancy. However, it is recommended to consult a doctor before using any medication during pregnancy.

What is the recommended dosage of Cefuroximum?

The recommended dosage of Cefuroximum depends on the severity of the infection. It is recommended to consult a doctor for the exact dosage.

Can Cefuroximum be used in children?

Yes, Cefuroximum can be used in children. However, the dosage may need to be adjusted according to the severity of the infection.

Can Cefuroximum be taken with food?

Yes, Cefuroximum can be taken with food. However, it is recommended to take the medication with a full glass of water.

Does Cefuroximum cause weight gain?

No, Cefuroximum does not cause weight gain. However, it is recommended to consult a doctor if any unusual symptom is observed.

Is Cefuroximum an over the counter drug?

No, Cefuroximum is not available as an over the counter drug. It is available with a doctor's prescription.

What is the shelf life of Cefuroximum?

The shelf life of Cefuroximum is two years when stored under proper conditions.

Can Cefuroximum cause a yeast infection?

Yes, Cefuroximum may cause a yeast infection as a side effect.

What are the common side effects of Cefuroximum?

The common side effects of Cefuroximum include nausea, vomiting, dizziness, headache, or diarrhea.

Can Cefuroximum be used to treat a sinus infection?

Yes, Cefuroximum is commonly used to treat a sinus infection.

What are the contraindications of Cefuroximum?

Cefuroximum should not be used in patients with hypersensitivity to cephalosporin, penicillin, or any other medication.

Can Cefuroximum be taken long term?

Yes, Cefuroximum can be taken long term under the supervision of a doctor.

Can Cefuroximum be used to treat a urinary tract infection?

Yes, Cefuroximum is commonly used to treat a urinary tract infection.

Does Cefuroximum cause headache?

Yes, Cefuroximum may cause a headache as a side effect.

Can Cefuroximum be used to treat an ear infection?

Yes, Cefuroximum is commonly used to treat an ear infection.

What should be avoided while taking Cefuroximum?

Alcohol and grapefruit should be avoided while taking Cefuroximum.

What is the generic name of Cefuroximum?

The generic name of Cefuroximum is cefuroxime axetil.

Can Cefuroximum be used to treat pneumonia?

Yes, Cefuroximum can be used to treat pneumonia.

What are the pharmacological actions of Cefuroximum?

Cefuroximum has antibacterial, anti-inflammatory, and immunomodulatory actions.

What is the dose of Cefuroximum for adults?

The dose of Cefuroximum for adults is 250mg-500mg twice daily.

Can Cefuroximum be used to treat an STD?

Yes, Cefuroximum can be used to treat some Sexually Transmitted Diseases.

Does Cefuroximum interact with other medications?

Yes, Cefuroximum may interact with other medications such as aspirin and ibuprofen.

Can Cefuroximum cause diarrhea?

Yes, Cefuroximum may cause diarrhea as a side effect.

How long does it take for Cefuroximum to work?

It can take up to several days for Cefuroximum to start working. However, the exact time depends on the severity of the infection.

Does Cefuroximum cause drowsiness?

Yes, Cefuroximum may cause drowsiness as a side effect.

How is Cefuroximum administered?

Cefuroximum is administered orally in tablet or capsule form.

Can Cefuroximum be used to treat a strep throat?

Yes, Cefuroximum is commonly used to treat a strep throat.

Does Cefuroximum cause stomach upset?

Yes, Cefuroximum may cause stomach upset as a side effect.

Does Cefuroximum treat UTI?

Yes, Cefuroximum is commonly used to treat UTI (Urinary Tract Infection).

What is the dosage of Cefuroximum for children?

The dosage of Cefuroximum for children depends on the age and weight of the child. It is recommended to consult a doctor for the exact dosage.

Is Cefuroximum an antibiotic?

Yes, Cefuroximum is an antibiotic used to treat a wide variety of bacterial infections.

Is Cefuroximum effective against staphylococcus aureus?

Yes, Cefuroximum is effective against staphylococcus aureus.

What is the usual duration of treatment for Cefuroximum?

The usual duration of treatment with Cefuroximum is 5-7 days.

Does Cefuroximum have an expiration date?

Yes, Cefuroximum has an expiration date. It is recommended to check the expiration date before using the medication.

Can Cefuroximum be used to treat a sinus infection?

Yes, Cefuroximum is commonly used to treat a sinus infection.

Is Cefuroximum an over the counter drug?

No, Cefuroximum is not available as an over the counter drug. It is available with a doctor's prescription.