Clorfenamina

Clorfenamina Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clorfenamina is a brand name. Its generic name is Chlorpheniramine.

Clorfenamina Introduction

Clorfenamina is an antihistamine used to treat the symptoms of hay fever, allergies, the common cold, hives and other types of allergies. It works by blocking the action of histamine, a substance produced by the body when it becomes hypersensitive to an allergen. It helps to relieve sneezing, itching, stuffy nose, and watery eyes caused by these conditions.

Clorfenamina Uses

Clorfenamina is used to treat a variety of allergic conditions, including hay fever, allergic rhinitis, hives, and contact dermatitis. It is also used to treat nausea and vomiting caused by certain drugs or conditions, such as chemotherapy or motion sickness.

Clorfenamina Mechanism of Action

Clorfenamina blocks the effects of histamine, a chemical produced by the body during an allergic reaction. Histamine attaches to H1 receptors, which are found in the nose, skin, lungs, and gastrointestinal tract. When it attaches to these receptors, it causes sneezing, itching, watery eyes, and other symptoms of an allergic reaction. Clorfenamina blocks the action of histamine on H1 receptors, leading to relief of symptoms.

How Long Does Clorfenamina Take to Work?

Clorfenamina typically takes 30 minutes to 1 hour to start working. However, in some cases it may take up to 4 hours to start working.

Clorfenamina Absorption, Route of Elimination and Dosage

Clorfenamina is absorbed rapidly from the gastrointestinal tract. It is then quickly metabolized by the liver and eliminated from the body primarily through the kidneys. The recommended dose for chlorpheniramine is 4 mg to 8 mg in adults taken every 4-6 hours. For children, the dose depends on age and weight: 2-5 years: 2 mg; 6-11 years: 4mg; 12 years and older, the adult dose of 4-8mg.

Clorfenamina Administration

Clorfenamina is available as a tablet and liquid suspension. It can be taken orally with or without food.

Clorfenamina Side Effects

Common side effects of chlorpheniramine include drowsiness, dry mouth, stomach upset, dizziness, headache, and fatigue.

Clorfenamina Toxicity

Clorfenamina is generally well tolerated but overdose of the medication may cause toxicity. Symptoms of overdose include confusion, convulsions, difficulty breathing, dry mouth, drowsiness, muscle twitching, nausea and vomiting, pale skin, rapid heart rate, and restlessness.

Clorfenamina Precaution

Clorfenamina should be used with caution in patients with liver or kidney disease, glaucoma, narrow angle glaucoma, prostate hypertrophy, and urinary retention. It should also be used with caution in elderly patients, as they are more likely to be sensitive to the sedative effects of the drug.

Clorfenamina Interaction, Disease Interaction, Drug Interaction, and Food Interactions

Clorfenamina can interact with medications used to treat anxiety, depression, forearm, high blood pressure, diabetes, epilepsy, and insomnia. It can also interact with alcohol, sedatives, muscle relaxants, and opioid pain medications. Clorfenamina can interact with certain diseases or medical conditions, such as asthma, heart disease, high blood pressure, kidney disease, liver disease, and urinary retention. Clorfenamina may interact with other medications or herbal supplements taken at the same time. It is important to tell your doctor about all the medications or supplements you are taking before using chlorpheniramine. Clorfenamina can interact with certain foods, such as high-fat foods, coffee, and grapefruit juice. It is important to tell your doctor about all the foods you eat before taking chlorpheniramine.

Pregnancy and Lactation Use

Clorfenamina should be used with caution during pregnancy, as it may cause harm to the developing fetus. It is not recommended for use during lactation.

Acute Overdose

Overdose of chlorpheniramine can cause severe side effects, including drowsiness, confusion, convulsions, difficulty breathing, dry mouth, flushing, muscle twitching, nausea, restlessness, shallow breathing, and slow/irregular heartbeat.

Contraindication

Clorfenamina is contraindicated in patients with known hypersensitivity to the drug.

Use Direction

Clorfenamina should be taken orally with or without food, as directed by your doctor. The dose for adults is 4 mg to 8 mg taken every 4-6 hours. The dose for children 2-5 years is 2 mg. The dose for children 6-11 years is 4mg. The dose for children 12-years and older is the same as for adults.

Storage Condition

Clorfenamina tablets and liquid suspension should be stored at room temperature, away from moisture and heat. Keep out of reach of children.

Volume of Distribution, Half Life, Clearance

Clorfenamina has a volume of distribution of 0.64 L/kg following intravenous administration. The elimination half-life of chlorpheniramine is 14 hours in adults and 30 hours in children. The clearance of chlorpheniramine is 2.5 L/hr/kg in adults and 6.3 L/hr/kg in children.

Here you find in details version of Clorfenamina

Some Frequently Asked Questions About Clorfenamina

What is Clorfenamina?

Clorfenamina is an antihistamine that is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies. It works by blocking the effects of histamine, a substance in the body that causes allergy symptoms.

What are the side effects of Clorfenamina?

The most common side effects of this drug include dry mouth, drowsiness, nausea and dizziness. Other side effects may include headaches, constipation, blurred vision, confusion, irritability and decreased appetite.

What are the dosages for Clorfenamina?

The dosages may vary depending on the patient's age and weight. It is available in tablet, syrup and injection form. For adults, the usual dose is 4-8 milligrams taken orally every 4-6 hours, maximum of 24 milligrams in 1 day. For children, the usual dose is 0.4 milligrams per kilogram of body weight every 6-12 hours, maximum of 4 milligrams per kilogram in 1 day.

Can Clorfenamina be used for children?

Yes, it can be used for children over the age of 2. However, it is important to consult your pediatrician before giving it to a child.

Can I take Clorfenamina with other medications?

Yes, it can be taken with other medications, but it is important to consult your doctor before taking any other medication while taking Clorfenamina.

What are the interactions of Clorfenamina?

Clorfenamina may interact with other medications, such as monoamine oxidase inhibitors (MAOIs), sympathomimetics, narcotic analgesics, anticholinergics, bronchodilators, muscle relaxants, and other antihistamines. It is important to consult your doctor before taking any other medications while taking Clorfenamina.

Does Clorfenamina cause drowsiness?

Yes, Clorfenamina may cause drowsiness in some people. Therefore, it is important to use caution when driving, operating machinery, or performing any activity that requires alertness.

Is it ok to drink alcohol while taking Clorfenamina?

No, it is not recommended to drink alcohol while taking Clorfenamina as it can increase the risk of side effects.

Does Clorfenamina cause weight gain?

No, Clorfenamina does not cause weight gain. However, some people may experience increased appetite or cravings while taking this medication.

Can I take Clorfenamina while pregnant?

It is not recommended to take Clorfenamina while pregnant, as it may be harmful to the fetus. Consult your doctor before taking this medication if you are pregnant.

How long does Clorfenamina take to work?

It usually takes 30-60 minutes for Clorfenamina to begin working. However, the effects may vary depending on the severity of the allergic reaction.

How long does Clorfenamina stay in your system?

The half-life of Clorfenamina is 8-14 hours, which means that it takes about 8-14 hours for the body to eliminate half of the dose. It is usually eliminated from your system within 3 days of stopping the medication.

How should I store Clorfenamina?

Clorfenamina should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is Clorfenamina habit-forming?

No, Clorfenamina is not habit-forming, but it can cause mild dependence if it is taken regularly for an extended period of time. This means that it may be harder for the body to respond to it if it is abruptly stopped.

What is Clorfenamina used to treat?

Clorfenamina is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies.

Can Clorfenamina be used for itching?

Yes, this drug can be used for itching due to allergic reactions. However, it is important to consult your doctor before using this drug for itching.

How long can I take Clorfenamina for?

Clorfenamina is usually taken for a few days to a few weeks, depending on the severity of the allergy symptoms. If your symptoms persist for more than two weeks, it is important to consult your doctor.

Is Clorfenamina safe for long-term use?

Long-term use of Clorfenamina is generally not recommended, as it can cause side effects such as drowsiness, dizziness, nausea, confusion, and blurred vision. Consult your doctor before continuing to take this drug for an extended period of time.

Can I overdose on Clorfenamina?

Yes, it is possible to overdose on Clorfenamina. Signs of an overdose may include confusion, drowsiness, dizziness, nausea, flushing, headache, and vomiting. Seek medical attention immediately if you think you have overdosed.

Who should not take Clorfenamina?

This drug should not be taken by people who are allergic to any of the ingredients in it, people with narrow-angle glaucoma, people with urinary retention, or people with obstructive gastrointestinal conditions.

What should I do if I miss a dose of Clorfenamina?

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra doses to make up for a missed one.

Does Clorfenamina interact with any foods or other substances?

Yes, Clorfenamina may interact with certain foods and alcoholic beverages. It is important to consult your doctor before consuming highfat meals, grapefruit juice, alcoholic beverages, or other substances that may interact with this medication.

Are there any herbal or dietary supplements that I should avoid while taking Clorfenamina?

It is important to consult your doctor before taking any herbal or dietary supplements while taking this drug. Some herbal remedies or dietary supplements may increase the risk of side effects or interact with the medication.

What should I do if I experience any side effects while taking Clorfenamina?

If you experience any side effects, such as drowsiness, dizziness, nausea, loss of appetite, or blurred vision, stop taking Clorfenamina and contact your doctor or healthcare provider immediately.

Should I avoid any activities while taking Clorfenamina?

Yes, it is important to avoid activities that require alertness, such as driving, operating heavy machinery, or performing any other activities that are potentially dangerous. You should also avoid drinking alcohol while taking this medication, as it can increase the risk of side effects.

Does Clorfenamina cause dry mouth?

Yes, dry mouth is a common side effect of Clorfenamina. To reduce the risk of this side effect, it is important to drink plenty of fluids and to avoid any beverages that contain caffeine.

Is Clorfenamina available over the counter?

Yes, Clorfenamina is available over-the-counter in many countries. However, it is still important to consult your doctor before taking this medication.

How long should I wait before eating or drinking after taking Clorfenamina?

It is recommended to wait at least 30 minutes after taking Clorfenamina before eating or drinking. This will help ensure that the drug is fully absorbed into your system.

Is there a generic version of Clorfenamina?

Yes, Clorfenamina is available in generic form, which is much less expensive than the brand-name version.

Can Clorfenamina be used to treat asthma?

No, Clorfenamina is not recommended for the treatment of asthma. However, it can be used to treat allergic reactions that can lead to asthma symptoms.

What are the alternatives to Clorfenamina?

Other antihistamines that can be used instead of Clorfenamina include cetirizine, loratadine, desloratadine, and fexofenadine. Speak to your doctor to discuss which medication is best for your symptoms.

Can Clorfenamina be used for allergies to insect stings and bites?

Yes, Clorfenamina can be used to treat allergic reactions to insect stings and bites. However, make sure to consult your doctor before taking any medication for this type of reaction.

Can Clorfenamina reduce hives caused by allergies?

Yes, this medication can be used to reduce hives caused by allergies. It works by blocking the action of histamine, which is a substance in the body that causes hives.

Does Clorfenamina work for food allergies?

Yes, Clorfenamina can be used to treat allergic reactions to certain foods. However, it is important to speak to your doctor before taking any medication for this type of reaction.

Can Clorfenamina be used for eye allergies?

Yes, Clorfenamina can be used to treat eye allergies due to pollen, animal dander, or other airborne allergens. However, it is important to consult your doctor before taking this medication for eye allergies.

Can Clorfenamina be used for skin allergies?

Yes, this medication can be used to treat skin allergy symptoms such as rash and itching. However, make sure to consult your doctor before taking any medication for this type of reaction.

Can Clorfenamina be used for pet allergies?

Yes, this medication can be used to treat allergy symptoms caused by pet dander, such as nasal congestion and sneezing. However, make sure to consult your doctor before taking any medication for this type of reaction.

Is Clorfenamina safe for cats?

No, Clorfenamina is not recommended for cats as it can be toxic if administered in large amounts. Speak to your veterinarian if you think your cat may be experiencing allergies.

Can I take Clorfenamina with ibuprofin?

Yes, it is safe to take Clorfenamina with ibuprofen. However, if you experience any adverse reactions, be sure to seek medical attention immediately.

Can I take Clorfenamina with antibiotics?

Yes, it is safe to take Clorfenamina with antibiotics. However, if you experience any adverse reactions, be sure to seek medical attention immediately.

Will Clorfenamina help with nausea?

No, Clorfenamina is not recommended for the treatment of nausea. Consult your doctor for more effective treatments for nausea.

https://www.medicinesfaq.com/brand/clorfenamina, http://classyfire.wishartlab.com/tax_nodes/C0000000, http://classyfire.wishartlab.com/tax_nodes/C0000002, http://classyfire.wishartlab.com/tax_nodes/C0000089, http://classyfire.wishartlab.com/tax_nodes/C0000184, http://classyfire.wishartlab.com/tax_nodes/C0000184, http://classyfire.wishartlab.com/tax_nodes/C0001099, http://classyfire.wishartlab.com/tax_nodes/C0003899, http://classyfire.wishartlab.com/tax_nodes/C0001030, http://classyfire.wishartlab.com/tax_nodes/C0004144, http://classyfire.wishartlab.com/tax_nodes/C0002239, http://classyfire.wishartlab.com/tax_nodes/C0004139, http://classyfire.wishartlab.com/tax_nodes/C0004557, http://classyfire.wishartlab.com/tax_nodes/C0001516, http://classyfire.wishartlab.com/tax_nodes/C0004150, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:52010, http://www.hmdb.ca/metabolites/HMDB0001944, http://www.genome.jp/dbget-bin/www_bget?drug:D07398, http://www.genome.jp/dbget-bin/www_bget?cpd:C06905, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2725, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508253, https://www.chemspider.com/Chemical-Structure.2624.html, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35938, https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=2400, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=52010, https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL505, http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000336, http://www.pharmgkb.org/drug/PA448960, http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1213, http://www.rxlist.com/cgi/generic/chlorpheniramine.htm, https://www.drugs.com/cdi/chlorpheniramine.html, https://en.wikipedia.org/wiki/Chlorphenamine,