Clorfeniramina

Clorfeniramina Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Clorfeniramina is a brand name. Its generic name is Chlorpheniramine.

Clorfeniramina Introduction

Clorfeniramina is an antihistamine used to treat the symptoms of hay fever, allergies, the common cold, hives and other types of allergies. It works by blocking the action of histamine, a substance produced by the body when it becomes hypersensitive to an allergen. It helps to relieve sneezing, itching, stuffy nose, and watery eyes caused by these conditions.

Clorfeniramina Uses

Clorfeniramina is used to treat a variety of allergic conditions, including hay fever, allergic rhinitis, hives, and contact dermatitis. It is also used to treat nausea and vomiting caused by certain drugs or conditions, such as chemotherapy or motion sickness.

Clorfeniramina Mechanism of Action

Clorfeniramina blocks the effects of histamine, a chemical produced by the body during an allergic reaction. Histamine attaches to H1 receptors, which are found in the nose, skin, lungs, and gastrointestinal tract. When it attaches to these receptors, it causes sneezing, itching, watery eyes, and other symptoms of an allergic reaction. Clorfeniramina blocks the action of histamine on H1 receptors, leading to relief of symptoms.

How Long Does Clorfeniramina Take to Work?

Clorfeniramina typically takes 30 minutes to 1 hour to start working. However, in some cases it may take up to 4 hours to start working.

Clorfeniramina Absorption, Route of Elimination and Dosage

Clorfeniramina is absorbed rapidly from the gastrointestinal tract. It is then quickly metabolized by the liver and eliminated from the body primarily through the kidneys. The recommended dose for chlorpheniramine is 4 mg to 8 mg in adults taken every 4-6 hours. For children, the dose depends on age and weight: 2-5 years: 2 mg; 6-11 years: 4mg; 12 years and older, the adult dose of 4-8mg.

Clorfeniramina Administration

Clorfeniramina is available as a tablet and liquid suspension. It can be taken orally with or without food.

Clorfeniramina Side Effects

Common side effects of chlorpheniramine include drowsiness, dry mouth, stomach upset, dizziness, headache, and fatigue.

Clorfeniramina Toxicity

Clorfeniramina is generally well tolerated but overdose of the medication may cause toxicity. Symptoms of overdose include confusion, convulsions, difficulty breathing, dry mouth, drowsiness, muscle twitching, nausea and vomiting, pale skin, rapid heart rate, and restlessness.

Clorfeniramina Precaution

Clorfeniramina should be used with caution in patients with liver or kidney disease, glaucoma, narrow angle glaucoma, prostate hypertrophy, and urinary retention. It should also be used with caution in elderly patients, as they are more likely to be sensitive to the sedative effects of the drug.

Clorfeniramina Interaction, Disease Interaction, Drug Interaction, and Food Interactions

Clorfeniramina can interact with medications used to treat anxiety, depression, forearm, high blood pressure, diabetes, epilepsy, and insomnia. It can also interact with alcohol, sedatives, muscle relaxants, and opioid pain medications. Clorfeniramina can interact with certain diseases or medical conditions, such as asthma, heart disease, high blood pressure, kidney disease, liver disease, and urinary retention. Clorfeniramina may interact with other medications or herbal supplements taken at the same time. It is important to tell your doctor about all the medications or supplements you are taking before using chlorpheniramine. Clorfeniramina can interact with certain foods, such as high-fat foods, coffee, and grapefruit juice. It is important to tell your doctor about all the foods you eat before taking chlorpheniramine.

Pregnancy and Lactation Use

Clorfeniramina should be used with caution during pregnancy, as it may cause harm to the developing fetus. It is not recommended for use during lactation.

Acute Overdose

Overdose of chlorpheniramine can cause severe side effects, including drowsiness, confusion, convulsions, difficulty breathing, dry mouth, flushing, muscle twitching, nausea, restlessness, shallow breathing, and slow/irregular heartbeat.

Contraindication

Clorfeniramina is contraindicated in patients with known hypersensitivity to the drug.

Use Direction

Clorfeniramina should be taken orally with or without food, as directed by your doctor. The dose for adults is 4 mg to 8 mg taken every 4-6 hours. The dose for children 2-5 years is 2 mg. The dose for children 6-11 years is 4mg. The dose for children 12-years and older is the same as for adults.

Storage Condition

Clorfeniramina tablets and liquid suspension should be stored at room temperature, away from moisture and heat. Keep out of reach of children.

Volume of Distribution, Half Life, Clearance

Clorfeniramina has a volume of distribution of 0.64 L/kg following intravenous administration. The elimination half-life of chlorpheniramine is 14 hours in adults and 30 hours in children. The clearance of chlorpheniramine is 2.5 L/hr/kg in adults and 6.3 L/hr/kg in children.

Here you find in details version of Clorfeniramina

Some Frequently Asked Questions About Clorfeniramina

What is Clorfeniramina?

Clorfeniramina is an antihistamine that is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies. It works by blocking the effects of histamine, a substance in the body that causes allergy symptoms.

What are the side effects of Clorfeniramina?

The most common side effects of this drug include dry mouth, drowsiness, nausea and dizziness. Other side effects may include headaches, constipation, blurred vision, confusion, irritability and decreased appetite.

What are the dosages for Clorfeniramina?

The dosages may vary depending on the patient's age and weight. It is available in tablet, syrup and injection form. For adults, the usual dose is 4-8 milligrams taken orally every 4-6 hours, maximum of 24 milligrams in 1 day. For children, the usual dose is 0.4 milligrams per kilogram of body weight every 6-12 hours, maximum of 4 milligrams per kilogram in 1 day.

Can Clorfeniramina be used for children?

Yes, it can be used for children over the age of 2. However, it is important to consult your pediatrician before giving it to a child.

Can I take Clorfeniramina with other medications?

Yes, it can be taken with other medications, but it is important to consult your doctor before taking any other medication while taking Clorfeniramina.

What are the interactions of Clorfeniramina?

Clorfeniramina may interact with other medications, such as monoamine oxidase inhibitors (MAOIs), sympathomimetics, narcotic analgesics, anticholinergics, bronchodilators, muscle relaxants, and other antihistamines. It is important to consult your doctor before taking any other medications while taking Clorfeniramina.

Does Clorfeniramina cause drowsiness?

Yes, Clorfeniramina may cause drowsiness in some people. Therefore, it is important to use caution when driving, operating machinery, or performing any activity that requires alertness.

Is it ok to drink alcohol while taking Clorfeniramina?

No, it is not recommended to drink alcohol while taking Clorfeniramina as it can increase the risk of side effects.

Does Clorfeniramina cause weight gain?

No, Clorfeniramina does not cause weight gain. However, some people may experience increased appetite or cravings while taking this medication.

Can I take Clorfeniramina while pregnant?

It is not recommended to take Clorfeniramina while pregnant, as it may be harmful to the fetus. Consult your doctor before taking this medication if you are pregnant.

How long does Clorfeniramina take to work?

It usually takes 30-60 minutes for Clorfeniramina to begin working. However, the effects may vary depending on the severity of the allergic reaction.

How long does Clorfeniramina stay in your system?

The half-life of Clorfeniramina is 8-14 hours, which means that it takes about 8-14 hours for the body to eliminate half of the dose. It is usually eliminated from your system within 3 days of stopping the medication.

How should I store Clorfeniramina?

Clorfeniramina should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is Clorfeniramina habit-forming?

No, Clorfeniramina is not habit-forming, but it can cause mild dependence if it is taken regularly for an extended period of time. This means that it may be harder for the body to respond to it if it is abruptly stopped.

What is Clorfeniramina used to treat?

Clorfeniramina is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies.

Can Clorfeniramina be used for itching?

Yes, this drug can be used for itching due to allergic reactions. However, it is important to consult your doctor before using this drug for itching.

How long can I take Clorfeniramina for?

Clorfeniramina is usually taken for a few days to a few weeks, depending on the severity of the allergy symptoms. If your symptoms persist for more than two weeks, it is important to consult your doctor.

Is Clorfeniramina safe for long-term use?

Long-term use of Clorfeniramina is generally not recommended, as it can cause side effects such as drowsiness, dizziness, nausea, confusion, and blurred vision. Consult your doctor before continuing to take this drug for an extended period of time.

Can I overdose on Clorfeniramina?

Yes, it is possible to overdose on Clorfeniramina. Signs of an overdose may include confusion, drowsiness, dizziness, nausea, flushing, headache, and vomiting. Seek medical attention immediately if you think you have overdosed.

Who should not take Clorfeniramina?

This drug should not be taken by people who are allergic to any of the ingredients in it, people with narrow-angle glaucoma, people with urinary retention, or people with obstructive gastrointestinal conditions.

What should I do if I miss a dose of Clorfeniramina?

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra doses to make up for a missed one.

Does Clorfeniramina interact with any foods or other substances?

Yes, Clorfeniramina may interact with certain foods and alcoholic beverages. It is important to consult your doctor before consuming highfat meals, grapefruit juice, alcoholic beverages, or other substances that may interact with this medication.

Are there any herbal or dietary supplements that I should avoid while taking Clorfeniramina?

It is important to consult your doctor before taking any herbal or dietary supplements while taking this drug. Some herbal remedies or dietary supplements may increase the risk of side effects or interact with the medication.

What should I do if I experience any side effects while taking Clorfeniramina?

If you experience any side effects, such as drowsiness, dizziness, nausea, loss of appetite, or blurred vision, stop taking Clorfeniramina and contact your doctor or healthcare provider immediately.

Should I avoid any activities while taking Clorfeniramina?

Yes, it is important to avoid activities that require alertness, such as driving, operating heavy machinery, or performing any other activities that are potentially dangerous. You should also avoid drinking alcohol while taking this medication, as it can increase the risk of side effects.

Does Clorfeniramina cause dry mouth?

Yes, dry mouth is a common side effect of Clorfeniramina. To reduce the risk of this side effect, it is important to drink plenty of fluids and to avoid any beverages that contain caffeine.

Is Clorfeniramina available over the counter?

Yes, Clorfeniramina is available over-the-counter in many countries. However, it is still important to consult your doctor before taking this medication.

How long should I wait before eating or drinking after taking Clorfeniramina?

It is recommended to wait at least 30 minutes after taking Clorfeniramina before eating or drinking. This will help ensure that the drug is fully absorbed into your system.

Is there a generic version of Clorfeniramina?

Yes, Clorfeniramina is available in generic form, which is much less expensive than the brand-name version.

Can Clorfeniramina be used to treat asthma?

No, Clorfeniramina is not recommended for the treatment of asthma. However, it can be used to treat allergic reactions that can lead to asthma symptoms.

What are the alternatives to Clorfeniramina?

Other antihistamines that can be used instead of Clorfeniramina include cetirizine, loratadine, desloratadine, and fexofenadine. Speak to your doctor to discuss which medication is best for your symptoms.

Can Clorfeniramina be used for allergies to insect stings and bites?

Yes, Clorfeniramina can be used to treat allergic reactions to insect stings and bites. However, make sure to consult your doctor before taking any medication for this type of reaction.

Can Clorfeniramina reduce hives caused by allergies?

Yes, this medication can be used to reduce hives caused by allergies. It works by blocking the action of histamine, which is a substance in the body that causes hives.

Does Clorfeniramina work for food allergies?

Yes, Clorfeniramina can be used to treat allergic reactions to certain foods. However, it is important to speak to your doctor before taking any medication for this type of reaction.

Can Clorfeniramina be used for eye allergies?

Yes, Clorfeniramina can be used to treat eye allergies due to pollen, animal dander, or other airborne allergens. However, it is important to consult your doctor before taking this medication for eye allergies.

Can Clorfeniramina be used for skin allergies?

Yes, this medication can be used to treat skin allergy symptoms such as rash and itching. However, make sure to consult your doctor before taking any medication for this type of reaction.

Can Clorfeniramina be used for pet allergies?

Yes, this medication can be used to treat allergy symptoms caused by pet dander, such as nasal congestion and sneezing. However, make sure to consult your doctor before taking any medication for this type of reaction.

Is Clorfeniramina safe for cats?

No, Clorfeniramina is not recommended for cats as it can be toxic if administered in large amounts. Speak to your veterinarian if you think your cat may be experiencing allergies.

Can I take Clorfeniramina with ibuprofin?

Yes, it is safe to take Clorfeniramina with ibuprofen. However, if you experience any adverse reactions, be sure to seek medical attention immediately.

Can I take Clorfeniramina with antibiotics?

Yes, it is safe to take Clorfeniramina with antibiotics. However, if you experience any adverse reactions, be sure to seek medical attention immediately.

Will Clorfeniramina help with nausea?

No, Clorfeniramina is not recommended for the treatment of nausea. Consult your doctor for more effective treatments for nausea.

https://www.medicinesfaq.com/brand/clorfeniramina, http://classyfire.wishartlab.com/tax_nodes/C0000000, http://classyfire.wishartlab.com/tax_nodes/C0000002, http://classyfire.wishartlab.com/tax_nodes/C0000089, http://classyfire.wishartlab.com/tax_nodes/C0000184, http://classyfire.wishartlab.com/tax_nodes/C0000184, http://classyfire.wishartlab.com/tax_nodes/C0001099, http://classyfire.wishartlab.com/tax_nodes/C0003899, http://classyfire.wishartlab.com/tax_nodes/C0001030, http://classyfire.wishartlab.com/tax_nodes/C0004144, http://classyfire.wishartlab.com/tax_nodes/C0002239, http://classyfire.wishartlab.com/tax_nodes/C0004139, http://classyfire.wishartlab.com/tax_nodes/C0004557, http://classyfire.wishartlab.com/tax_nodes/C0001516, http://classyfire.wishartlab.com/tax_nodes/C0004150, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:52010, http://www.hmdb.ca/metabolites/HMDB0001944, http://www.genome.jp/dbget-bin/www_bget?drug:D07398, http://www.genome.jp/dbget-bin/www_bget?cpd:C06905, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2725, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508253, https://www.chemspider.com/Chemical-Structure.2624.html, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35938, https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=2400, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=52010, https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL505, http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000336, http://www.pharmgkb.org/drug/PA448960, http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1213, http://www.rxlist.com/cgi/generic/chlorpheniramine.htm, https://www.drugs.com/cdi/chlorpheniramine.html, https://en.wikipedia.org/wiki/Chlorphenamine,