Benzoate De Benzyle

Benzoate De Benzyle Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Benzoate De Benzyle is a brand name. Its generic name is Benzyl Benzoate.

Introduction

Benzoate De Benzyle is a synthetic ester derived from benzoic acid used as a pharmaceutical excipient, a preservative, and as a solubilizing agent. It is a colorless, slightly viscous, and nonflammable liquid that is insoluble in water and oil but soluble in alcohol, propylene glycol, and other organic solvents. It has a fruity, pleasant smell. It is found in cosmetics, fragrances, and detergents.

Uses

Benzoate De Benzyle is used in pharmaceutical products as a preservative and solubilizing agent. It is also used as a topical medicine to treat lice and scabies. It can also be used to treat pruritus, cystitis, and fungal infections. Additionally, it can be used on the skin as an insect repellent and a preservative in cosmetics.

Mechanism of Action

Benzoate De Benzyle acts by disrupting the protective barrier on the cuticle of the lice, destroying the louse's protective coating and subsequently killing it. As a preservative, it works by inhibiting the growth of microorganisms and fungi in cosmetics and other products.

How Long Does it Take to Work?

Benzoate De Benzyle typically takes several hours to take full effect in killing lice. When used as a preservative, it begins inhibiting microbial growth within minutes.

Absorption

Benzoate De Benzyle is quickly absorbed when applied topically to the skin and quickly eliminated by metabolism.

Route of Elimination

Benzoate De Benzyle is metabolized to benzoic acid and Benzyl Alcohol, which are both eliminated in the urine.

Dosage

Doses of Benzoate De Benzyle for topical application vary depending on the application. For lice, it is recommended to use a 1 - 5% solution to be applied to the skin for 12 - 24 hours. For scabies, a 13 - 20% solution is recommended to be applied to the skin for 12 - 24 hours. The maximum tolerated dose should not be exceeded.

Administration

Benzoate De Benzyle should be administered topically to the skin. It is not to be taken orally or injected.

Side Effect

Common side effects of Benzoate De Benzyle include burning, itching, flaking, redness of the skin, and a foul odor. Other more serious side effects include rashes, hives, difficulty breathing, and tightness in the chest.

Toxicity

Benzoate De Benzyle has been classified as an irritant and a mild skin sensitizer. High concentrations may cause skin irritation and sensitization.

Precaution

Care should be taken when applying Benzoate De Benzyle to ensure that it does not come into contact with eyes, mouth, or mucous membranes. It should not be used on healthy skin or on broken, raw, or inflamed skin. It should also not be used on children younger than two years of age.

Interaction

Benzoate De Benzyle may interact with other drugs that may be absorbed through the skin, such as benzoyl peroxide, retinoids, or topical antibiotics. It may also interact with other topical products, such as sunscreen or moisturizers.

Disease Interactions

Benzoate De Benzyle may not be suitable for patients with a history of skin allergies or sensitivities, eczema, psoriasis, or diabetes. It should be used with caution in these cases.

Drug Interactions

Benzoate De Benzyle may interact with other drugs taken orally or applied topically, such as antibiotics, retinoids, or products containing salicylic acid.

Food Interactions

Benzoate De Benzyle may interact with certain foods, such as dairy products, eggs, nuts, seafood, and wheat.

Pregnancy Use

Benzoate De Benzyle should not be used during pregnancy.

Lactation Use

Benzoate De Benzyle should not be used while breastfeeding.

Acute Overdose

An acute overdose of Benzoate De Benzyle may cause skin irritation, breathing difficulty, or other serious adverse reactions. Immediate medical attention should be sought if an overdose is suspected.

Contraindication

Benzoate De Benzyle is contraindicated in patients with known hypersensitivity or allergies to benzoic acid or its derivatives.

Use Directions

When using Benzoate De Benzyle, it is important to follow any use directions provided by your doctor or pharmacist. If you do not understand the instructions given to you, contact your doctor for clarification.

Storage Condition

Benzoate De Benzyle should be stored at room temperature away from direct sunlight and heat sources. It should also be kept away from children and pets.

Volume of Distribution

The volume of distribution of Benzoate De Benzyle is approximately 87.6L.

Half Life

The half-life of Benzoate De Benzyle in adults is approximately 12.5 hours.

Clearance

The clearance of Benzoate De Benzyle in adults is approximately 27.7 L/min.

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Some Frequently Asked Questions About Benzoate De Benzyle

What is Benzoate De Benzyle?

Benzoate De Benzyle is an ester of Benzoic acid found in a variety of cosmetics, pharmaceuticals, and insect repellents. It acts as a fragrance fixative, viscosity booster, and a preservative in products such as creams, lotions, aftershaves, and colognes.

Why is Benzoate De Benzyle used?

Benzoate De Benzyle is widely used in a variety of skin and cosmetic products because of its excellent solvent and preservative qualities. It also helps to prevent the product from becoming rancid or losing its fragrance. It helps products maintain their consistency and prolongs shelf life.

What are the skin benefits of Benzoate De Benzyle?

Benzoate De Benzyle can be a beneficial additive for skin care products. It can help to keep products from becoming rancid, while also keeping the product from becoming contaminated with bacteria or other microorganisms. Additionally, Benzoate De Benzyle helps to improve the feel of the product and thicken its consistency.

How does Benzoate De Benzyle work?

Benzoate De Benzyle is an aromatic ester of Benzoic acid. It acts as a fragrance fixative and helps to prevent the product from losing its scent or becoming contaminated with bacteria or other microorganisms. Benzoate De Benzyle also helps to improve the feel of the product and thicken its consistency.

What is the chemical structure of Benzoate De Benzyle?

The chemical structure of Benzoate De Benzyle is C7H8O2. It is an aromatic ester of Benzoic acid with a clear liquid appearance.

What are the side effects of Benzoate De Benzyle?

In general, Benzoate De Benzyle is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Benzoate De Benzyle's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.

What is Benzoate De Benzyle used for?

Benzoate De Benzyle is used in a variety of skin and cosmetic products as a fragrance fixative, viscosity booster, and preservative. It can help to keep products from becoming rancid, while also helping to prevent the product from becoming contaminated with bacteria or other microorganisms. Additionally, Benzoate De Benzyle helps to improve the feel of the product and thicken its consistency.

What is the safety of Benzoate De Benzyle?

In general, Benzoate De Benzyle is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Benzoate De Benzyle's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.

Is Benzoate De Benzyle safe for skin contact?

Benzoate De Benzyle is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that because of its potential for irritation, Benzoate De Benzyle should not be used on sensitive areas such as the eyes, and it should not be used on pets.

Is Benzoate De Benzyle toxic?

Benzoate De Benzyle is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, and itching in some people. Therefore, it is important to note that Benzoate De Benzyle should not be used on sensitive areas such as the eyes, and it should not be used on pets.

What products contain Benzoate De Benzyle?

Benzoate De Benzyle is found in a variety of skin and cosmetic products such as creams, lotions, aftershaves, colognes, deodorants, and insect repellents. It is also an ingredient in some pharmaceuticals.

What is the shelf life of a product containing Benzoate De Benzyle?

The shelf life of a product containing Benzoate De Benzyle depends on its formulation, production process, packaging, storage conditions, and other factors. Generally, products containing Benzoate De Benzyle have a shelf life of 1-2 years.

Is Benzoate De Benzyle a natural ingredient?

No, Benzoate De Benzyle is a synthetic ingredient that is derived from the reaction of benzoic acid and benzyl alcohol.

Is Benzoate De Benzyle safe for pregnant women?

It is recommended that pregnant women avoid the use of products containing Benzoate De Benzyle as it may be absorbed through the skin. It is best to consult with a doctor before using such products.

Is Benzoate De Benzyle safe for children?

Benzoate De Benzyle is generally considered to be safe when used in small, infrequent doses, but it is still recommended to consult with a doctor before using such products on children.

What is the molecular formula of Benzoate De Benzyle?

The molecular formula of Benzoate De Benzyle is C7H8O2.

How is Benzoate De Benzyle made?

Benzoate De Benzyle is made through the reaction of benzoic acid and benzyl alcohol. Depending on the method of production, different grades of Benzoate De Benzyle may be produced.

Is Benzoate De Benzyle a volatile compound?

Yes, Benzoate De Benzyle is a volatile compound and has a boiling point of 243°C.

Is Benzoate De Benzyle petroleum-based?

No, Benzoate De Benzyle is derived from plant-based materials and is not petroleum-based.

What is the boiling point of Benzoate De Benzyle?

The boiling point of Benzoate De Benzyle is 243°C.

Is Benzoate De Benzyle used in cosmetics?

Yes, Benzoate De Benzyle is commonly used in many skin care and cosmetic products as a preservative, fragrance fixative, and viscosity booster. It also helps to prevent the product from becoming rancid or losing its fragrance.

Does Benzoate De Benzyle absorb water?

Yes, Benzoate De Benzyle is hygroscopic, meaning it has the ability to absorb moisture from the air.

Does Benzoate De Benzyle cause skin irritation?

Benzoate De Benzyle may cause skin irritation in some people. Therefore, it is important to be aware of any potential irritation, dryness, or itching reactions, and discontinue use of the product if irritation occurs.

What is the odor of Benzoate De Benzyle?

The odor of Benzoate De Benzyle is sweet and balsamic.

Is Benzoate De Benzyle combustible?

Yes, Benzoate De Benzyle is combustible and needs to be stored away from sources of heat.

Can Benzoate De Benzyle be used in pharmaceuticals?

Yes, Benzoate De Benzyle is commonly used in a variety of pharmaceuticals, such as drugs, tablets, liquids, and creams.

What is the melting point of Benzoate De Benzyle?

The melting point of Benzoate De Benzyle is 18-21°C.

Can Benzoate De Benzyle be used to repel insects?

Yes, Benzoate De Benzyle is commonly used in a variety of insect repellents, such as mosquito repellents. It is important to follow the instructions on the product.

What is the Flash Point of Benzoate De Benzyle?

The flash point of Benzoate De Benzyle is 99°C.

Is Benzoate De Benzyle flammable?

Yes, Benzoate De Benzyle is flammable and needs to be stored away from sources of heat.

Can Benzoate De Benzyle be ingested?

No, Benzoate De Benzyle should not be ingested as it may be toxic if ingested in large amounts.

Can Benzoate De Benzyle be used as a preservative?

Yes, Benzoate De Benzyle is commonly used in a variety of skin care and cosmetic products as a preservative.

Is Benzoate De Benzyle toxic to humans?

In general, Benzoate De Benzyle is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may be toxic when ingested in large amounts.

Is Benzoate De Benzyle water-soluble?

Yes, Benzoate De Benzyle is water-soluble and can easily be dissolved in oil.

Does Benzoate De Benzyle penetrate the skin?

Yes, Benzoate De Benzyle may be absorbed through the skin when applied topically, though the amount of absorption is typically limited.

Is Benzoate De Benzyle a photosensitizer?

No, Benzoate De Benzyle is not a photosensitizer and will not cause any sensitization or sun-sensitivity reactions.

Can Benzoate De Benzyle be used in bath preparations?

Yes, Benzoate De Benzyle is often used in bath preparations, such as bath salts, since it helps to improve the feel of the product and thicken its consistency.

Is Benzoate De Benzyle an endocrine disruptor?

No, Benzoate De Benzyle is not an endocrine disruptor and does not cause any disruption to the body's normal hormone production.

Is Benzoate De Benzyle a carcinogen?

No, Benzoate De Benzyle is not a known carcinogen.

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