Benzyl Benzoat
Benzyl Benzoat Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Benzyl Benzoat is a brand name. Its generic name is Benzyl Benzoate.
Introduction
Benzyl Benzoat is a synthetic ester derived from benzoic acid used as a pharmaceutical excipient, a preservative, and as a solubilizing agent. It is a colorless, slightly viscous, and nonflammable liquid that is insoluble in water and oil but soluble in alcohol, propylene glycol, and other organic solvents. It has a fruity, pleasant smell. It is found in cosmetics, fragrances, and detergents.Uses
Benzyl Benzoat is used in pharmaceutical products as a preservative and solubilizing agent. It is also used as a topical medicine to treat lice and scabies. It can also be used to treat pruritus, cystitis, and fungal infections. Additionally, it can be used on the skin as an insect repellent and a preservative in cosmetics.Mechanism of Action
Benzyl Benzoat acts by disrupting the protective barrier on the cuticle of the lice, destroying the louse's protective coating and subsequently killing it. As a preservative, it works by inhibiting the growth of microorganisms and fungi in cosmetics and other products.How Long Does it Take to Work?
Benzyl Benzoat typically takes several hours to take full effect in killing lice. When used as a preservative, it begins inhibiting microbial growth within minutes.Absorption
Benzyl Benzoat is quickly absorbed when applied topically to the skin and quickly eliminated by metabolism.Route of Elimination
Benzyl Benzoat is metabolized to benzoic acid and Benzyl Alcohol, which are both eliminated in the urine.Dosage
Doses of Benzyl Benzoat for topical application vary depending on the application. For lice, it is recommended to use a 1 - 5% solution to be applied to the skin for 12 - 24 hours. For scabies, a 13 - 20% solution is recommended to be applied to the skin for 12 - 24 hours. The maximum tolerated dose should not be exceeded.Administration
Benzyl Benzoat should be administered topically to the skin. It is not to be taken orally or injected.Side Effect
Common side effects of Benzyl Benzoat include burning, itching, flaking, redness of the skin, and a foul odor. Other more serious side effects include rashes, hives, difficulty breathing, and tightness in the chest.Toxicity
Benzyl Benzoat has been classified as an irritant and a mild skin sensitizer. High concentrations may cause skin irritation and sensitization.Precaution
Care should be taken when applying Benzyl Benzoat to ensure that it does not come into contact with eyes, mouth, or mucous membranes. It should not be used on healthy skin or on broken, raw, or inflamed skin. It should also not be used on children younger than two years of age.Interaction
Benzyl Benzoat may interact with other drugs that may be absorbed through the skin, such as benzoyl peroxide, retinoids, or topical antibiotics. It may also interact with other topical products, such as sunscreen or moisturizers.Disease Interactions
Benzyl Benzoat may not be suitable for patients with a history of skin allergies or sensitivities, eczema, psoriasis, or diabetes. It should be used with caution in these cases.Drug Interactions
Benzyl Benzoat may interact with other drugs taken orally or applied topically, such as antibiotics, retinoids, or products containing salicylic acid.Food Interactions
Benzyl Benzoat may interact with certain foods, such as dairy products, eggs, nuts, seafood, and wheat.Pregnancy Use
Benzyl Benzoat should not be used during pregnancy.Lactation Use
Benzyl Benzoat should not be used while breastfeeding.Acute Overdose
An acute overdose of Benzyl Benzoat may cause skin irritation, breathing difficulty, or other serious adverse reactions. Immediate medical attention should be sought if an overdose is suspected.Contraindication
Benzyl Benzoat is contraindicated in patients with known hypersensitivity or allergies to benzoic acid or its derivatives.Use Directions
When using Benzyl Benzoat, it is important to follow any use directions provided by your doctor or pharmacist. If you do not understand the instructions given to you, contact your doctor for clarification.Storage Condition
Benzyl Benzoat should be stored at room temperature away from direct sunlight and heat sources. It should also be kept away from children and pets.Volume of Distribution
The volume of distribution of Benzyl Benzoat is approximately 87.6L.Half Life
The half-life of Benzyl Benzoat in adults is approximately 12.5 hours.Clearance
The clearance of Benzyl Benzoat in adults is approximately 27.7 L/min.Here you find in details version of Benzyl Benzoat
Some Frequently Asked Questions About Benzyl Benzoat
What is Benzyl Benzoat?
Benzyl Benzoat is an ester of Benzoic acid found in a variety of cosmetics, pharmaceuticals, and insect repellents. It acts as a fragrance fixative, viscosity booster, and a preservative in products such as creams, lotions, aftershaves, and colognes.
Why is Benzyl Benzoat used?
Benzyl Benzoat is widely used in a variety of skin and cosmetic products because of its excellent solvent and preservative qualities. It also helps to prevent the product from becoming rancid or losing its fragrance. It helps products maintain their consistency and prolongs shelf life.
What are the skin benefits of Benzyl Benzoat?
Benzyl Benzoat can be a beneficial additive for skin care products. It can help to keep products from becoming rancid, while also keeping the product from becoming contaminated with bacteria or other microorganisms. Additionally, Benzyl Benzoat helps to improve the feel of the product and thicken its consistency.
How does Benzyl Benzoat work?
Benzyl Benzoat is an aromatic ester of Benzoic acid. It acts as a fragrance fixative and helps to prevent the product from losing its scent or becoming contaminated with bacteria or other microorganisms. Benzyl Benzoat also helps to improve the feel of the product and thicken its consistency.
What is the chemical structure of Benzyl Benzoat?
The chemical structure of Benzyl Benzoat is C7H8O2. It is an aromatic ester of Benzoic acid with a clear liquid appearance.
What are the side effects of Benzyl Benzoat?
In general, Benzyl Benzoat is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Benzyl Benzoat's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.
What is Benzyl Benzoat used for?
Benzyl Benzoat is used in a variety of skin and cosmetic products as a fragrance fixative, viscosity booster, and preservative. It can help to keep products from becoming rancid, while also helping to prevent the product from becoming contaminated with bacteria or other microorganisms. Additionally, Benzyl Benzoat helps to improve the feel of the product and thicken its consistency.
What is the safety of Benzyl Benzoat?
In general, Benzyl Benzoat is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Benzyl Benzoat's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.
Is Benzyl Benzoat safe for skin contact?
Benzyl Benzoat is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that because of its potential for irritation, Benzyl Benzoat should not be used on sensitive areas such as the eyes, and it should not be used on pets.
Is Benzyl Benzoat toxic?
Benzyl Benzoat is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, and itching in some people. Therefore, it is important to note that Benzyl Benzoat should not be used on sensitive areas such as the eyes, and it should not be used on pets.
What products contain Benzyl Benzoat?
Benzyl Benzoat is found in a variety of skin and cosmetic products such as creams, lotions, aftershaves, colognes, deodorants, and insect repellents. It is also an ingredient in some pharmaceuticals.
What is the shelf life of a product containing Benzyl Benzoat?
The shelf life of a product containing Benzyl Benzoat depends on its formulation, production process, packaging, storage conditions, and other factors. Generally, products containing Benzyl Benzoat have a shelf life of 1-2 years.
Is Benzyl Benzoat a natural ingredient?
No, Benzyl Benzoat is a synthetic ingredient that is derived from the reaction of benzoic acid and benzyl alcohol.
Is Benzyl Benzoat safe for pregnant women?
It is recommended that pregnant women avoid the use of products containing Benzyl Benzoat as it may be absorbed through the skin. It is best to consult with a doctor before using such products.
Is Benzyl Benzoat safe for children?
Benzyl Benzoat is generally considered to be safe when used in small, infrequent doses, but it is still recommended to consult with a doctor before using such products on children.
What is the molecular formula of Benzyl Benzoat?
The molecular formula of Benzyl Benzoat is C7H8O2.
How is Benzyl Benzoat made?
Benzyl Benzoat is made through the reaction of benzoic acid and benzyl alcohol. Depending on the method of production, different grades of Benzyl Benzoat may be produced.
Is Benzyl Benzoat a volatile compound?
Yes, Benzyl Benzoat is a volatile compound and has a boiling point of 243°C.
Is Benzyl Benzoat petroleum-based?
No, Benzyl Benzoat is derived from plant-based materials and is not petroleum-based.
What is the boiling point of Benzyl Benzoat?
The boiling point of Benzyl Benzoat is 243°C.
Is Benzyl Benzoat used in cosmetics?
Yes, Benzyl Benzoat is commonly used in many skin care and cosmetic products as a preservative, fragrance fixative, and viscosity booster. It also helps to prevent the product from becoming rancid or losing its fragrance.
Does Benzyl Benzoat absorb water?
Yes, Benzyl Benzoat is hygroscopic, meaning it has the ability to absorb moisture from the air.
Does Benzyl Benzoat cause skin irritation?
Benzyl Benzoat may cause skin irritation in some people. Therefore, it is important to be aware of any potential irritation, dryness, or itching reactions, and discontinue use of the product if irritation occurs.
What is the odor of Benzyl Benzoat?
The odor of Benzyl Benzoat is sweet and balsamic.
Is Benzyl Benzoat combustible?
Yes, Benzyl Benzoat is combustible and needs to be stored away from sources of heat.
Can Benzyl Benzoat be used in pharmaceuticals?
Yes, Benzyl Benzoat is commonly used in a variety of pharmaceuticals, such as drugs, tablets, liquids, and creams.
What is the melting point of Benzyl Benzoat?
The melting point of Benzyl Benzoat is 18-21°C.
Can Benzyl Benzoat be used to repel insects?
Yes, Benzyl Benzoat is commonly used in a variety of insect repellents, such as mosquito repellents. It is important to follow the instructions on the product.
What is the Flash Point of Benzyl Benzoat?
The flash point of Benzyl Benzoat is 99°C.
Is Benzyl Benzoat flammable?
Yes, Benzyl Benzoat is flammable and needs to be stored away from sources of heat.
Can Benzyl Benzoat be ingested?
No, Benzyl Benzoat should not be ingested as it may be toxic if ingested in large amounts.
Can Benzyl Benzoat be used as a preservative?
Yes, Benzyl Benzoat is commonly used in a variety of skin care and cosmetic products as a preservative.
Is Benzyl Benzoat toxic to humans?
In general, Benzyl Benzoat is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may be toxic when ingested in large amounts.
Is Benzyl Benzoat water-soluble?
Yes, Benzyl Benzoat is water-soluble and can easily be dissolved in oil.
Does Benzyl Benzoat penetrate the skin?
Yes, Benzyl Benzoat may be absorbed through the skin when applied topically, though the amount of absorption is typically limited.
Is Benzyl Benzoat a photosensitizer?
No, Benzyl Benzoat is not a photosensitizer and will not cause any sensitization or sun-sensitivity reactions.
Can Benzyl Benzoat be used in bath preparations?
Yes, Benzyl Benzoat is often used in bath preparations, such as bath salts, since it helps to improve the feel of the product and thicken its consistency.
Is Benzyl Benzoat an endocrine disruptor?
No, Benzyl Benzoat is not an endocrine disruptor and does not cause any disruption to the body's normal hormone production.
Is Benzyl Benzoat a carcinogen?
No, Benzyl Benzoat is not a known carcinogen.