Trotz
Trotz Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Trotz is a brand name. Its generic name is Racecadotril.
Trotz Introduction
Trotz is a generic drug used to treat diarrhea and helps reduce fluid loss in the intestine and helps reduce dehydration in adults and children. It belongs to the class of medications called 'spasmolytics' and works by blocking the absorption of sodium by the gastrointestinal tract, which causes increased water absorption and slower movements of food through the intestine.Uses for Trotz
Trotz is mainly used to treat diarrhoea in adults and children over one year of age. This medication is also used to manage mild-to-moderate inflammatory bowel disorders such as Crohn’s disease, ulcerative colitis, and irritable bowel syndrome. It also helps to reduce fluid loss in the intestine and helps reduce dehydration.Mechanism of Action
Trotz works by blocking the effects of certain neurotransmitters in the gastrointestinal tract. It also inhibits the absorption of sodium from the small intestine, which results in increased water absorption. As a result, stools are softer and movement of the stools is slowed down. This helps reduce the diarrhoea caused by infections, food intolerances, or other causes.How Long Does It Take to Work
Trotz usually starts working within 30 minutes after it's taken. The full effect of the drug typically lasts up to 6 hours, after which it starts to wear off gradually.Absorption
Trotz is readily and swiftly absorbed from the gastrointestinal tract after oral administration and reaches its maximal concentration in the bloodstream within 2 hours. The bioavailability of racecadotril is 97.5%.Route of Elimination
Trotz is rapidly converted by the liver before being eliminated primarily in the urine.Dosage
Trotz should be taken three times a day in divided doses. The dosage usually depends on the age, health condition, and response to treatment of the patient. It is recommended to begin treatment with a low dosage which may then be adjusted depending on the response to the drug.- For Adults: The recommended dose is 3 tablets (30 mg) each time, up to three times a day
- For Children: The recommended dose for children aged 1 year and above is 1 tablet (10 mg) each time, up to three times a day
Administration
Trotz should be taken orally, with liquid such as water, milk, or juice. It should be taken before meals, unless prescribed otherwise by the doctor.Side Effect
Common side effects of racecadotril include abdominal pain, nausea, vomiting, and headache. If these side effects persist or worsen, a doctor should be consulted for further medical advice and treatment.Toxicity
Trotz is generally considered safe when taken as directed. However, overdose of racecadotril can lead to serious and potentially life-threatening side effects and should be avoided.Precautions
Trotz should be used with caution in people with a history of kidney disease, as it may cause further damage to the kidneys. It should also be used with caution in people with high blood pressure or any other cardiovascular disorder as it may cause an increase in blood pressure.Interaction
Trotz may interact with other medications, such as antibiotics, anticoagulants, antihistamines, diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Therefore, it is important to consult a doctor or pharmacist before taking any new medications while taking racecadotril.Disease Interaction
Trotz may not be suitable for people with certain diseases or conditions, such as liver or kidney disease, high blood pressure, or heart disease. Therefore, it is important to consult a doctor before taking racecadotril.Drug Interaction
Trotz may interact with other medications, such as antibiotics, anticoagulants, antihistamines, diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Therefore, it is important to consult a doctor or pharmacist before taking any new medications while taking racecadotril.Food Interactions
Trotz may interact with certain foods or beverages, such as alcohol. Therefore, it is important to consult a doctor or pharmacist before consuming any food or beverage while taking racecadotril.Pregnancy Use
Trotz should be used with caution in pregnant women. It should not be used during the first trimester of pregnancy, and must be discussed with a doctor before taking it.Lactation Use
Trotz should not be taken while breastfeeding, as it is not known whether the drug passes into breast milk.Acute Overdose
If an overdose of racecadotril is suspected, contact the Poison Control Center immediately or go to the nearest emergency room.Contraindication
Trotz is contraindicated in people with allergies to the active ingredient or other ingredients in the drug, people with kidney or liver disease, or people with high blood pressure or any other cardiovascular disorder.Use Direction
Trotz should be taken as directed by a doctor or pharmacist. The dosage may vary according to the age, health condition, and response to treatment of the patient. It is important to take this medication with a full glass of liquid such as water, milk, or juice.Storage Condition
Trotz should be stored at room temperature, away from direct sunlight, moisture, and heat. It is also important to keep this medication out of reach of children.Volume of Distribution
The volume of distribution of racecadotril is 16 L/kg.Half Life
The half-life of racecadotril is approximately 2.5 hours.Clearance
The clearance of racecadotril is 110 mL/min/kg.Here you find in details version of Trotz
Some Frequently Asked Questions About Trotz
.What is Trotz?
Trotz is an antidiarrheal drug, commonly known as Hidrasec, which helps to treat gastrointestinal disturbances such as diarrhea caused by gastroenteritis. It is a relatively new medication, patented in 1987, and is effective in both adults and children.
How does Trotz work?
Trotz works by inhibiting the action of enzymes responsible for the production of water and electrolyte secretions in the small intestine. This helps to reduce the amount of water lost through the bowel and therefore decreases the frequency of diarrheal episodes.
Is Trotz safe for all ages?
Trotz is approved for use in adults and children over the age of 1 year. It is considered safe and well-tolerated, but it is important to speak to a doctor before giving it to infants or young children.
Is Trotz available over the counter?
No, Trotz is a prescription medication and not available for purchase without a prescription from a doctor.
What are the side effects of Trotz?
The most common side effects of Trotz are dizziness, headache, nausea and abdominal pain. There have also been some reports of allergic reactions and skin rashes. If any of these side effects occur, speak to your doctor.
What should I avoid while taking Trotz?
Avoid taking antacids or certain vitamins and minerals (such as iron, zinc and magnesium) for at least two hours before or after taking Trotz as these can interact with the medication.
How often should I take Trotz?
The usual dose of Trotz is one capsule three times daily. It is important to take it at regular intervals as directed by your doctor.
Is there a generic version of Trotz?
No, there is no available generic version of Trotz.
Can I take Trotz while pregnant?
It is not recommended to take Trotz during pregnancy as it has not been studied enough to guarantee its safety in pregnant women. Speak to your doctor about the best course of action.
Can I take Trotz when breastfeeding?
Trotz is excreted in breast milk, so it is not recommended to take it while breastfeeding. Speak to your doctor for advice on the best course of action.
Can I take Trotz with other medications?
Trotz can interact with certain other medications, so it is important to tell your doctor about any other medications you are taking. This includes any over-the-counter medications, vitamin supplements, herbal remedies and other prescription medications.
Can I drink alcohol while taking Trotz?
It is not recommended to drink alcohol while taking Trotz as this can increase the risk of side effects. If you do drink alcohol, it is important to speak to your doctor for advice.
Is Trotz addictive?
No, Trotz is not known to be addictive.
What is the dosage of Trotz
The standard dose of Trotz is one capsule three times daily. Do not exceed this dose, and always follow the instructions of your doctor.
What happens if I take an overdose of Trotz?
If you take an overdose of Trotz, seek medical attention immediately. Overdoses of Trotz can lead to serious side effects, such as dizziness, drowsiness, nausea, and difficulty breathing.
What should I do if I miss a dose of Trotz?
If you miss a dose of Trotz, take it as soon as you remember. Do not take double doses of the medication to make up for a forgotten dose.
Is Trotz suitable for long-term use?
Yes, Trotz can be used for long-term management of diarrheal episodes. However, it is important to talk to your doctor about it, as long-term use of Trotz may lead to certain side effects.
What are the possible interactions of Trotz?
Trotz may interact with certain medications, such as antacids, antibiotics, certain vitamins and minerals, and some herbal supplements. Speak to your doctor before taking Trotz alongside any other medication.
Is Trotz safe for children?
Yes, Trotz is approved for use in children over the age of 1 year. However, it is important to speak to a doctor before giving Trotz to an infant or young child.
Can Trotz be used to treat Crohn's disease?
No, Trotz is not approved for the treatment of Crohn's disease. Speak to your doctor for advice on the best course of action.
How long does Trotz take to work?
Trotz can begin to work within 30 minutes of administration. However, the full effects may take up to an hour or more to be felt.
Can I take Trotz with other antidiarrheal medications?
It is not recommended to take Trotz with other antidiarrheal medications as this can lead to an increase in side effects or the effectiveness of the treatment being reduced. Speak to your doctor for advice on the best course of action.
What is the recommended storage conditions for Trotz?
Trotz should be stored at room temperature, away from direct sunlight and heat. It should not be stored in the refrigerator or freezer, nor should it be exposed to extreme changes in temperature.
Can Trotz be taken with food?
Yes, Trotz can be taken with food. In fact, it is recommended to take it after meals to reduce the risk of side effects such as nausea.
Is Trotz available in in other forms?
No, Trotz is only available in capsule form.
Who manufactures Trotz?
Trotz is manufactured by the pharmaceutical company GlaxoSmithKline.
What are the inactive ingredients in Trotz?
The inactive ingredients in Trotz include lactose monohydrate, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, sodium starch glycolate, and polysorbate 80.
What is the cost of Trotz?
The cost of Trotz will vary depending on your insurance plan and where you purchase the medication. Speak to your doctor or pharmacist for more information.
Can Trotz cause a rash?
Yes, in rare cases Trotz may cause a rash. If you experience any skin rashes while taking Trotz, speak to your doctor.
Is Trotz used to treat irritable bowel syndrome?
No, Trotz is not approved for the treatment of irritable bowel syndrome.
Can Trotz cause constipation?
Yes, Trotz can cause constipation in rare cases. If you experience constipation while taking Trotz, speak to your doctor.
Can Trotz be taken with antiemetics?
Yes, Trotz can be taken with antiemetics, such as prochlorperazine and promethazine, as long as your doctor has approved it.
How long does Trotz stay in the body?
The effects of Trotz typically last for up to 8 hours, but the medication is metabolized and excreted quickly, so it is usually undetectable in the body within 24 hours.
How quickly does Trotz start to work?
The effects of Trotz usually begin to be felt within 30 minutes of administration. The full effects may take up to 1 hour or more to be felt.
What are the contraindications for Trotz?
Trotz is contraindicated in patients with severe hepatic impairment, as well as in patients with a known hypersensitivity to the active ingredient or any of the other ingredients in the medication.
Can Trotz be used to treat inflammatory bowel diseases?
No, Trotz is not approved for the treatment of inflammatory bowel diseases.
Is Trotz safe for people with kidney disease?
Yes, Trotz is usually safe for people with kidney disease. However, it is important to speak to a doctor before using it, as it can interact with certain medications.
Does Trotz interact with other medications?
Yes, Trotz can interact with certain medications, such as certain antibiotics, antacids, vitamins and minerals, and herbal supplements. Speak to your doctor before taking Trotz alongside any other medication.
Can Trotz be taken with probiotics?
Yes, Trotz can generally be taken with probiotics. However, it is important to speak to your doctor to ensure it is safe to do so.
Is Trotz gluten free?
Yes, Trotz is gluten free.
Can Trotz be used to treat viral gastroenteritis?
No, Trotz is not approved for the treatment of viral gastroenteritis.
How long should I take Trotz for?
Trotz should be taken for as long as your doctor prescribes it. It is not recommended to stop taking Trotz without speaking to a doctor first, as this can lead to an increased risk of relapse.
What is the dosage for Trotz in children?
The recommended dose of Trotz for children aged 1-5 years is 6 mg three times daily. For children aged 6-12 years, the recommended dose is 12 mg three times daily. Always follow the instructions of your doctor when administering Trotz to a child.
Is Trotz an antibiotic?
No, Trotz is not an antibiotic.
Can Trotz be used to treat gastroenteritis caused by bacterial infection?
Yes, Trotz can help to reduce the symptoms of gastroenteritis caused by bacteria, but it will not cure the infection itself. Antibiotics may be required to treat the underlying bacterial infection.
Does Trotz interact with other antidiarrheal medications?
Yes, Trotz can interact with certain other antidiarrheal medications, such as loperamide and diphenoxylate/atropine. Speak to your doctor before taking Trotz alongside any other antidiarrheal medication.