Tizmed

Tizmed Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tizmed is a brand name. Its generic name is Tizanidine.

Tizmed Introduction

Tizmed is a short-acting muscle relaxant used to treat spasticity, including muscle spasms, pain, and stiffness caused by neurological disorders such as cerebral palsy, multiple sclerosis, and spinal cord injuries. It is usually taken orally, but can also be injected into a muscle.

Uses For

Tizmed is used to treat spasticity resulting from diseases such as multiple sclerosis, spinal cord injuries, cerebral palsy, and stroke. It can also be used to relieve muscle spasms and pain.

Mechanism of Action

Tizmed works by blocking nerve signals from reaching the brain, thereby reducing the intensity of muscle spasms. It also relaxes muscles which can reduce pain and stiffness.

How Long Does it Take to Work?

Tizmed typically takes effect within 30 to 60 minutes after it is consumed. It is a short-acting medication, so the effects will usually last 8-9 hours.

Absorption

Tizmed is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached in 1-2 hours.

Route of Elimination

Tizmed is mainly eliminated by the kidneys. Approximately 20% is excreted unchanged in the urine.

Dosage

The recommended adult dose of tizanidine is 2-4 mg orally every 6-8 hours, not to exceed 36 mg in a 24 hour period. Maximum benefits may not be seen for up to 2-3 weeks. The maximum recommended daily dose is 36 mg.

Administration

Tizmed should be taken with food or immediately after eating. Do not take tizanidine with other drugs that cause drowsiness or decrease alertness. Examples of these drugs include tricyclic antidepressants, other muscle relaxants, pain relievers, sleeping pills, and tranquilizers.

Side Effects

Common side effects of tizanidine include dry mouth, drowsiness, dizziness, lightheadedness, headache, constipation, nausea, and weakness. More serious side effects may include low blood pressure, slowed breathing, and changes in mental status.

Toxicity

Tizmed may cause significant toxicity and death in overdose. Symptoms may include confusion, hallucinations, coma, seizures, and respiratory arrest. Treatment may include gastric lavage, activated charcoal, and supportive measures to control symptoms.

Precaution

Tizmed may cause drowsiness, dizziness, or blurred vision, and may impair physical or mental abilities required for the performance of potentially hazardous activities such as driving or operating machinery. Avoid these activities until you know how the drug affects you.

Interaction

Tizmed may interact with other drugs, such as anticholinergics, cimetidine, fluvoxamine, fluoxetine, nefazodone, and MAO inhibitors. Tell your doctor all medications and supplements you are taking before taking tizanidine.

Disease Interaction

Tizmed may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants.

Drug Interaction

Tizmed can interact with other drugs, including Nefazodone, Cimetidine, Fluoxetine, Fluvoxamine, and Monoamine Oxidase inhibitors (MAOI). Tell your doctor all medications and supplements you are taking before taking tizanidine.

Food Interactions

Tizmed may interact with food, beverages, or alcohol, causing side effects such as drowsiness, lightheadedness, dizziness, and blurred vision. Avoid these interactions by consuming tizanidine with food or at least 8 ounces of water.

Pregnancy Use

Tizmed should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Women who are pregnant or planning to become pregnant should inform their healthcare provider of this before taking tizanidine.

Lactation Use

Tizmed should not be used by breastfeeding women due to the potential for serious adverse reactions in nursing babies. Talk to your healthcare provider if you are breastfeeding before taking tizanidine.

Acute Overdose

Acute overdose symptoms may include drowsiness, confusion, impaired coordination, low blood pressure, and slow heartbeat. Treatment may include gastric lavage, activated charcoal, and supportive measures. Seek emergency medical help if an overdose is suspected.

Contraindication

Tizmed is contraindicated in patients with known hypersensitivity reactions to it, as well as those taking fluvoxamine, MAO inhibitors, or cimetidine.

Use Direction

Tizmed should be taken orally, with food or immediately after a meal. For maximum benefit, the medication should be taken at regular intervals. Do not take more than directed or change the dose without consulting a doctor.

Storage Condition

Tizmed should be stored at room temperature, away from direct light and moisture. Keep all medications away from children and pets.

Volume of Distribution

Tizmed has a volume of distribution of 0.9 L/kg.

Half Life

The half-life of tizanidine is 2.5-4.6 hours.

Clearance

The clearance of tizanidine is 1.2-3.2 mL/min/kg.

Here you find in details version of Tizmed

Some Frequently Asked Questions About Tizmed

What is Tizmed?

Tizmed is a centrally acting alpha-2 agonist used to treat spasticity, a condition caused by an injury or illness that results in muscle stiffness, tightness, and spasms.

What is the most common use of Tizmed?

The most common use of Tizmed is to treat spasticity associated with neurological conditions such as multiple sclerosis, spinal cord injury, and cerebral palsy.

How long does it take for Tizmed to start working?

Tizmed usually starts to work within 30 minutes to an hour after taking it.

How should I take Tizmed?

Take Tizmed exactly as prescribed by your doctor. Do not take more or less than prescribed. Do not take more than 3 tablets per day.

How long does Tizmed stay in your system?

Tizmed has a half-life of approximately 1 to 2 hours, meaning it will typically stay in your system for up to 8 hours.

Can I take Tizmed with other medications?

Tizmed may interact with certain other medications so make sure to tell your doctor about all the other medications you are taking.

What are the possible side effects of taking Tizmed?

Common side effects of taking Tizmed include dry mouth, drowsiness, dizziness, weakness, and fatigue. More severe side effects including low blood pressure, slow heart rate, and liver damage may also occur.

Is Tizmed addictive?

Tizmed is not known to be habit-forming or addictive, but it is important to take it as directed by your doctor.

Can I drink alcohol while taking Tizmed?

It is not recommended to drink alcohol while taking Tizmed, as it can increase the risk of side effects.

Does Tizmed treat muscle spasms?

Yes, Tizmed can be used to treat muscle spasms caused by spasticity.

Can Tizmed be used to relieve pain?

Tizmed is mainly used to treat spasticity, but it can also be used to relieve pain associated with muscle spasms.

Who should not take Tizmed?

Tizmed should not be taken by pregnant women, children, or those with liver or kidney disease. Additionally, those taking certain other medications should not take Tizmed.

Is Tizmed safe for long-term use?

Tizmed is generally safe for long-term use, but talk to your doctor if you have any concerns about taking this medication for an extended period of time.

Does Tizmed cause weight gain?

In some cases, Tizmed may cause weight gain. This is more likely to occur in elderly patients and those with kidney or liver disease.

Can I take Tizmed while breastfeeding?

It is not recommended to take Tizmed while breastfeeding, as it could pass into breast milk and affect the baby.

Can Tizmed be used to treat headaches?

No, Tizmed is not used to treat headaches. It is intended to treat spasticity caused by neurological conditions.

Does Tizmed cause depression or anxiety?

In some cases, Tizmed can cause depression or anxiety. If these side effects occur, speak with your doctor right away.

Is Tizmed available in generic form?

Yes, Tizmed is available in generic form.

How is Tizmed metabolized in the body?

Tizmed is metabolized in the liver by cytochrome P450 3A4.

Can Tizmed cause stomach upset?

Yes, Tizmed can cause stomach upset including nausea, vomiting, and diarrhea.

Can I take other medications with Tizmed?

Certain medications should not be taken with Tizmed, including medications used to treat epilepsy, depression and anxiety, and those containing cimetidine. Be sure to tell your doctor about all medications you are currently taking before starting Tizmed.

Does Tizmed interact with grapefruit juice?

Yes, Tizmed can interact with grapefruit juice and increase the risk of side effects.

What happens if I miss a dose of Tizmed?

If you miss a dose of Tizmed, take it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular schedule.

Can Tizmed be used to treat fibromyalgia?

Tizmed is not traditionally used to treat fibromyalgia, but it may be recommended by your doctor in certain cases.

Can Tizmed cause blurred vision?

Blurred vision is a possible side effect of taking Tizmed.

What should I do if I experience an allergic reaction to Tizmed?

If you experience any signs of an allergic reaction to Tizmed such as itching, swelling, or difficulty breathing, seek medical attention immediately.

What should I do if I experience drowsiness while taking Tizmed?

If you experience drowsiness while taking Tizmed, it is recommended to avoid activities that require alertness such as driving or operating heavy machinery.

Is Tizmed safe for children to take?

Tizmed is not recommended for use in children. Speak with your doctor if you are considering giving this medication to a child.

What else should I know about taking Tizmed?

Take Tizmed exactly as directed by your doctor. Do not take more or less than prescribed. Do not take more than 3 tablets per day. Do not stop taking Tizmed without first talking to your doctor. Be sure to tell your doctor about all medications you are currently taking.

Does Tizmed cause cognitive impairment?

In some cases, Tizmed may cause cognitive impairment such as confusion, memory problems, and difficulty concentrating.

Can Tizmed be used to treat insomnia?

Tizmed is not typically used to treat insomnia, but it can cause drowsiness in some cases which may help in falling and staying asleep.

Can I take Tizmed if I have high blood pressure?

It is not recommended to take Tizmed if you have high blood pressure, as it can cause further decreases in your blood pressure.

Can I take Tizmed while pregnant?

It is not recommended to take Tizmed while pregnant, as it may cause harm to the fetus.

Does Tizmed contain sulfa?

No, Tizmed does not contain sulfa.

Does Tizmed cause memory loss?

In some cases, Tizmed may cause memory loss and other cognitive impairments.

Does Tizmed interact with other medications?

Yes, Tizmed may interact with certain medications. Be sure to tell your doctor about all medications you are taking before starting Tizmed.

Should Tizmed be taken with food?

Tizmed may be taken with or without food.

What are the most common side effects of taking Tizmed?

The most common side effects of taking Tizmed include dry mouth, drowsiness, dizziness, weakness, and fatigue.

What should I avoid while taking Tizmed?

Avoid activities that require alertness such as driving or operating heavy machinery while taking Tizmed due to its drowsiness-causing side effects.

What is the recommended dosage of Tizmed for spasticity?

The recommended dosage of Tizmed for spasticity is 2-4 mg per day, taken either 2 or 3 times a day depending on the doctor's recommendation.

Does Tizmed cause difficulty urinating?

In some cases, Tizmed may cause difficulty urinating due to its effects on sphincter muscles in the bladder.

Can I take Tizmed with other muscle relaxants?

It is not recommended to take Tizmed with other muscle relaxants, as this may increase the risk of side effects.