Tivis
Tivis Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tivis is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Tivis (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Tivis is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Tivis works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Tivis can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Tivis is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Tivis is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Tivis is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Tivis should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Tivis may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Tivis use, however it can cause serious side effects in certain individuals.Precautions
- Tivis should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Tivis may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Tivis should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Tivis may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Tivis alongside any other medications.Food Interactions
Food interactions with Tivis are not known.Pregnancy Use
Tivis should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Tivis is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Tivis is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Tivis is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Tivis should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Tivis is not known.Half-Life
The half-life of Tivis is approximately 22 days.Clearance
The clearance of Tivis is not known.Here you find in details version of Tivis
Some Frequently Asked Questions About Tivis
you can give answe only.What is Tivis?
Tivis is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Tivis?
The chemical name of Tivis is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Tivis taken?
Tivis is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Tivis?
The most common side effects of Tivis include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Tivis?
The recommended dose of Tivis is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Tivis be used?
Tivis should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Tivis?
Tivis should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Tivis?
An overdose of Tivis can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Tivis is a medical emergency and should be treated as such.
What are the interactions of Tivis with other medications?
Tivis may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Tivis?
The shelf life of Tivis is three years from the date of manufacture.
Is Tivis used for pregnant women?
The safety of Tivis for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Tivis.
Is there any generic version of Tivis available?
No, there is not a generic version of Tivis available.
How long does it take for Tivis to take effect?
The effect of Tivis is usually immediate.
How often can Tivis be taken?
Tivis should not be taken more than once every six hours.
What are some alternatives to Tivis?
Alternatives to Tivis include adenosine, aminophylline, and calcium channel blockers.
Can Tivis be taken with other medications?
Yes, it is possible to take Tivis with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Tivis.
Can I take Tivis if I am breastfeeding?
No, Tivis is not recommended for women who are breastfeeding.
Is Tivis safe for children?
No, Tivis should not be given to children.
Can Tivis be used for pulmonary disorders?
No, Tivis is not recommended for the treatment of pulmonary disorders.
Does Tivis interfere with other medications?
Yes, Tivis can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Tivis be administered orally?
No, Tivis should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Tivis?
Tivis should not be taken more than once every six hours.
What should I do if I miss a dose of Tivis?
If you miss a dose of Tivis, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Tivis?
Common symptoms of an allergic reaction to Tivis include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Tivis with food?
Yes, it is okay to take Tivis with food.
Can I take Tivis if I’m on dialysis?
Tivis should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Tivis?
The cost of Tivis will vary depending on the dosage and the pharmacy where it is purchased.
Is Tivis habit-forming?
No, Tivis is not known to be habit-forming.
Can Tivis be used to treat arrhythmias?
Yes, Tivis is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Tivis?
The most common side effects of Tivis include dizziness, nausea, and sweating.
Does Tivis interact with other medications?
Yes, Tivis can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Tivis a controlled substance?
No, Tivis is not a controlled substance.
Should I take Tivis with food?
Yes, it is okay to take Tivis with food.
Can I take Tivis if I’m pregnant?
No, the safety of Tivis for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Tivis.
Can Tivis be given intramuscularly?
Yes, Tivis can be administered intramuscularly.
How should Tivis be stored?
Tivis should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Tivis?
The recommended dose of Tivis is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Tivis cause drowsiness?
Yes, Tivis can cause drowsiness.
Can I take Tivis if I’m taking other medications?
Yes, it is possible to take Tivis with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Tivis.
Is Tivis safe for the elderly?
Yes, Tivis is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Tivis be used to treat atrial fibrillation?
Yes, Tivis can be used to treat atrial fibrillation.
Can Tivis be used to treat ventricular tachycardia?
Yes, Tivis can be used to treat ventricular tachycardia.