Ofloxacino
Ofloxacino Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ofloxacino is a brand name. Its generic name is Ofloxacin.
Ofloxacino
Ofloxacino is an antibiotic medication used to treat certain types of infections. It can be used to treat various types of bacteria, such as respiratory tract infections, skin infections, urinary tract infections, and ear infections.
Uses for Ofloxacino
Ofloxacino is used to treat infections caused by a variety of bacteria, including: pneumonia, bronchitis, sinusitis, skin infections, urinary tract infections, and ear infections.
Mechanism of Action
Ofloxacino works by inhibiting the growth of bacteria by interfering with its DNA replication process. It binds to the bacterial DNA gyrase and topoisomerase IV enzymes, which are required for the replication of bacterial DNA.
How Long Does it Take to Work?
Ofloxacino typically begins to work within 48 hours of the start of treatment. The duration of treatment and the dosage may vary depending on the severity of the infection and the patient’s response to treatment.
Absorption
Ofloxacino is rapidly and completely absorbed after oral administration. It can also be given intravenously or intramuscularly.
Route of Elimination
Ofloxacino is mainly eliminated by the kidneys, with a small amount being metabolized by the liver. It is typically eliminated from the body within 24 hours.
Dosage
The dosage of ofloxacin depends on the type and severity of the infection being treated. Generally the recommended dosage is 200-400mg taken two to three times a day. Patients with impaired kidney function may need lower doses; in such cases the dose should be adjusted to the patient’s specific needs.
Administration
Ofloxacino can be administered orally, intramuscularly, or intravenously. When taken orally, the drug is typically taken with food or a non-alcoholic beverage.
Side Effect
Common side effects of ofloxacin include nausea, vomiting, diarrhea, constipation, dizziness, headache, lightheadedness, itching, rash, and changes in taste. More serious side effects may include: confusion, hallucinations, abdominal pain, seizures, and fever.
Toxicity
Ofloxacino is generally safe, however, it may be toxic if very high doses are taken. Symptoms of overdose include rapid heart rate, decreased breathing rate, confusion, and seizures.
Precautions
Before taking ofloxacin, it is important to tell your doctor if you are pregnant or breastfeeding, or if you have any liver or kidney problems, diabetes, or any allergies. It is also important to tell your doctor about any other medications, dietary supplements, or vitamins that you are taking, as these may interact with ofloxacin in a negative way.
Interaction
Ofloxacino may interact with other medications, including antibiotics, antacids, and steroids. It may also interact with certain vitamins, foods, and alcohol. It is important to tell your doctor about all of these potential interactions before taking ofloxacin.
Disease Interaction
Ofloxacino may interact with certain diseases, including diabetes, electrolyte imbalance, hypocalcemia, or renal or hepatic dysfunction. It is important to inform your doctor if you have any of these conditions before taking ofloxacin.
Drug Interaction
Ofloxacino may interact with certain medications, including antibiotics, antacids, and steroids. It is important to tell your doctor if you are taking any of these or other medications before taking ofloxacin.
Food Interactions
Ofloxacino may interact with certain foods, including milk products, dairy products, and fatty acids. It is important to tell your doctor if you are taking any of these or other foods before taking ofloxacin.
Pregnancy Use
Ofloxacino should be used with caution in pregnant women, as it may cause harm to the unborn baby. If you are pregnant, you should talk to your doctor before taking this medication.
Lactation Use
Ofloxacino has been known to pass into breast milk and may cause harm to a nursing baby. You should talk to your doctor before breastfeeding while taking this medication.
Acute Overdose
In cases of an overdose of ofloxacin, call your healthcare provider or poison control center right away. Symptoms of an overdose may include nausea, vomiting, dizziness, confusion, abdominal pain, seizures, and rapid heartbeat.
Contraindication
Ofloxacino is contraindicated in patients who have known hypersensitivity to the drug, as well as those with known history of seizures or liver problems. It is also contraindicated in patients taking drugs that can interact with ofloxacin.
Use Direction
Ofloxacino should be taken as prescribed by your healthcare provider. It can be taken with food, but should be taken with plenty of water. Do not skip doses and do not take more or less than prescribed. Do not stop taking the medication before finishing the full course, even if you feel better, as this may result in the infection coming back.
Storage Conditions
Ofloxacino should be stored at room temperature away from light and moisture. Keep it away from pets and children.
Volume of Distribution
The volume of distribution of ofloxacin is approximately 1.2L/kg.
Half Life
The half-life of ofloxacin is about 6-8 hours.
Clearance
Ofloxacino has a clearance of roughly 1.3 mL/min/kg.
Here you find in details version of Ofloxacino
Some Frequently Asked Questions About Ofloxacino
What is Ofloxacino?
Ofloxacino is a prescription antibiotic used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, and infection of the prostate (prostatitis).
How does Ofloxacino work?
Ofloxacino works by preventing bacteria from producing the proteins needed for them to multiply and survive. This stops the infection from spreading and allows the body to fight off the infection.
What is the dosage of Ofloxacino?
The dosage varies depending on the type and severity of the infection being treated. For adults, the usual dose is 200-400 mg every 12 hours for 10-14 days. The maximum dose is 800 mg.
What are the side effects of Ofloxacino?
Common side effects of Ofloxacino include nausea, vomiting, stomach pain, headache, dizziness, drowsiness, blurred vision, and ringing in the ears. If any of these side effects become severe or do not go away, talk to your doctor or pharmacist.
What should I avoid while taking Ofloxacino?
Avoid drinking alcohol while taking Ofloxacino, as this can increase the risk of certain side effects. It is also important to avoid direct exposure to sunlight or artificial sources of ultraviolet (UV) light, such as tanning beds, as Ofloxacino may cause your skin to become more sensitive to UV light.
Should I take Ofloxacino with food?
You may take Ofloxacino either with or without food. Taking it with food may reduce stomach upset. However, it is important to drink a full glass of water with each dose.
Is Ofloxacino safe to take during pregnancy?
It is not known if Ofloxacino is safe to take during pregnancy. As with any medication, talk to your doctor before taking Ofloxacino if you are pregnant or planning to become pregnant.
What if I forget to take a dose of Ofloxacino?
If it is almost time for your next dose, skip the missed dose and take the next dose at the regular time. Do not take two doses at the same time. If you have any questions, talk to your doctor or pharmacist.
Can I take other medications with Ofloxacino?
Do not take any other medications, including over-the-counter medications, vitamins, or supplements without first talking to your doctor. Some medications can interact with Ofloxacino and should not be taken at the same time.
What should I do if I experience an allergic reaction to Ofloxacino?
If you experience symptoms of an allergic reaction such as rash, hives, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat, stop taking Ofloxacino and seek immediate medical attention.
Can Ofloxacino be used to treat infections caused by viruses?
No, Ofloxacino only works against bacteria. It is not effective for treating infections caused by viruses, such as colds or the flu.
Can I take Ofloxacino with dairy products?
It is recommended that you take Ofloxacino at least 2 hours before or after taking dairy products, as dairy products can reduce the effectiveness of the medication.
Can I drink alcohol while taking Ofloxacino?
It is not recommended that you drink alcohol while taking Ofloxacino, as this can increase the risk of certain side effects.
What should I do if I experience side effects from taking Ofloxacino?
If any side effects become severe or do not go away, talk to your doctor or pharmacist. It is important to tell them about any side effects that you experience, even if they seem minor.
Can I still exercise while taking Ofloxacino?
Yes, it is safe to exercise while taking Ofloxacino. However, it is important to drink plenty of fluids to prevent dehydration, as this can increase the risk of certain side effects.
Does Ofloxacino interact with other medications?
Yes, Ofloxacino can interact with other medications. Do not take any other medications, including over-the-counter medications, vitamins, or supplements without first talking to your doctor.
Can I take acetaminophen while I am taking Ofloxacino?
Yes, you can take acetaminophen while taking Ofloxacino, as long as the dose is appropriate. However, it is important to avoid taking more than the recommended dose of acetaminophen.
Are there any foods or beverages I should avoid while taking Ofloxacino?
It is recommended that you avoid taking Ofloxacino at the same time as dairy products as they can reduce the effectiveness of the medication. You should also avoid drinking alcohol while taking Ofloxacino as this can increase the risk of certain side effects.
Can I take other antibiotics at the same time as Ofloxacino?
No, it is not recommended that you take other antibiotics at the same time as Ofloxacino, as this could lead to the development of bacterial resistance. Talk to your doctor before taking any other antibiotics.
Can I take Ofloxacino while breastfeeding?
Yes, Ofloxacino can be taken while breastfeeding. However, it is important to talk to your doctor before taking any medications while breastfeeding, as some medications can pass into breast milk.
Can Ofloxacino cause itching or skin rash?
Yes, Ofloxacino can cause itching or skin rash. If you experience any of these symptoms, talk to your doctor or pharmacist. They may be able to change your medication to reduce the chance of these symptoms occurring.
Can Ofloxacino cause drowsiness?
Yes, Ofloxacino can cause drowsiness in some people. If you experience drowsiness after taking Ofloxacino, it is important not to drive or operate heavy machinery until the effects have worn off.
Can I take Ofloxacino for a long period of time?
Yes, you can take Ofloxacino for a long period of time, but it is important to talk to your doctor first. Long-term use of Ofloxacino may increase the risk of certain side effects.
What is the shelf life of Ofloxacino?
The shelf life of Ofloxacino tablets is 36 months after manufacture and 28 days after opening the package. It is important to take note of the expiration date printed on the package and never use expired medication.
Is Ofloxacino an antibiotic and does it kill bacteria?
Yes, Ofloxacino is an antibiotic. It works by preventing bacteria from producing the proteins they need to multiply and survive, thus killing the bacteria and treating the infection.
Is Ofloxacino safe for children to take?
Ofloxacino is approved for use in children and adolescents aged 1 year and older. However, talk to your doctor before giving Ofloxacino to a child, as there may be some safety concerns.
Can children take the same dose of Ofloxacino as adults?
No, the dose of Ofloxacino for children is different from the dose for adults. Talk to your doctor or pharmacist for information about the correct dosage for your child.
Does Ofloxacino treat gonorrhea?
Yes, Ofloxacino is used to treat gonorrhea. However, it is important to take a full course of the medication to ensure that all of the bacteria causing the infection have been killed.
What is the mechanism of action of Ofloxacino?
Ofloxacino works by preventing bacteria from producing the proteins needed for them to multiply and survive. This stops the infection from spreading and allows the body to fight off the infection.
Do I need to finish the entire course of Ofloxacino?
Yes, it is important to finish the entire course of Ofloxacino. Stopping treatment too soon can lead to the infection coming back or becoming resistant to the medication.
Can Ofloxacino be used to treat a sinus infection?
Yes, Ofloxacino can be used to treat a sinus infection. Talk to your doctor for information about the correct dosage and duration of treatment.
Can I take Ofloxacino if I have kidney disease?
Yes, Ofloxacino can be taken if you have kidney disease. However, the dose may need to be adjusted, as Ofloxacino is eliminated from the body by the kidneys. Talk to your doctor or pharmacist for more information.
Is Ofloxacino available as a generic?
Yes, Ofloxacino is available as a generic medication. It may be less expensive than the brand-name version of the drug, but it is equally effective.
Can I take Ofloxacino if I am allergic to penicillin?
Yes, you can take Ofloxacino if you are allergic to penicillin. Ofloxacino is a different type of antibiotic and does not contain penicillin.
Is Ofloxacino used to treat strep throat?
Yes, Ofloxacino is sometimes used to treat strep throat. However, it is important to talk to your doctor first, as strep throat is caused by a type of bacteria that is not always sensitive to Ofloxacino.
Do I need a prescription to buy Ofloxacino?
Yes, Ofloxacino is a prescription medication and you will need a prescription from your doctor to buy it. Do not take Ofloxacino without first consulting your doctor.
Can Ofloxacino be used to treat ear infections?
Yes, Ofloxacino can be used to treat certain types of ear infections. Talk to your doctor or pharmacist to determine if Ofloxacino is the appropriate treatment for your condition.