Nitrofurantoin Macrocrystal

Nitrofurantoin Macrocrystal Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nitrofurantoin Macrocrystal is a brand name. Its generic name is Nitrofurantoin.

Introduction

Nitrofurantoin Macrocrystal is an antibiotic medication used primarily to treat bladder infections. It's used to treat most types of urinary tract infections in both adults and children. It works by stopping bacteria from growing in the bladder and urinary system.

Uses of Nitrofurantoin Macrocrystal

Nitrofurantoin Macrocrystal is used to treat urinary tract infections, including cystitis and bladder infections. It is also used to prevent recurrence of these infections.

Mechanism of Action

Nitrofurantoin Macrocrystal works by inhibiting bacterial enzymes essential for the synthesis of DNA and cell wall production. This prevents bacteria from producing new cells and stops their growth.

How Long Does It Take to Work?

Nitrofurantoin Macrocrystal usually takes 2 to 3 days to start working. Some people may notice improvement after only one day.

Absorption

Nitrofurantoin Macrocrystal is only partially and slowly absorbed into the blood after being taken orally. Its concentration in the blood is typically low.

Route of Elimination

Nitrofurantoin Macrocrystal is primarily eliminated in urine. It is excreted in the urine as a mixture of unchanged drug and its metabolites.

Dosage

Nitrofurantoin Macrocrystal is available in the form of tablets, capsules, and suspension. It is usually taken two or three times a day for 5 to 10 days, depending on the severity of the infection.

• Adults and children 12 years and over: 100 mg twice a day for 7 days.
• Children 11 years and younger: 5 mg/kg/day (up to a maximum of 100 mg/day) for 7 days.

Administration

Nitrofurantoin Macrocrystal should be taken at least 2 hours after eating and on an empty stomach. It should also be taken with plenty of fluids to help reduce the risk of crystals forming in the urine.

Side Effects

Common side effects of nitrofurantoin include nausea, vomiting, headache, fever, rash, and abdominal pain. It can also cause diarrhea and changes in blood tests.

Toxicity

Nitrofurantoin Macrocrystal is generally well tolerated and has a low risk of toxicity. However, overdose or misuse can lead to serious side effects such as kidney damage and anemia.

Precautions

It is important to follow your doctor's instructions when taking nitrofurantoin. Do not take more than your prescribed dose and take it with plenty of fluids to reduce the risk of kidney stones forming.

Interactions

Nitrofurantoin Macrocrystal may interact with certain medications, herbal supplements, and vitamins. Before taking this medication, be sure to tell your doctor about all the medications you are taking.

Disease Interactions

Nitrofurantoin Macrocrystal may interact with certain chronic medical conditions such as chronic kidney disease or anemia. It is important to tell your doctor about any chronic conditions before taking this medication.

Drug Interactions

Nitrofurantoin Macrocrystal may interact with common medications such as antacids, laxatives, and vitamins. Be sure to tell your doctor about all the medications you are taking before taking this medication.

Food Interactions

Nitrofurantoin Macrocrystal should be taken on an empty stomach. It should not be taken with food or milk.

Pregnancy Use

Nitrofurantoin Macrocrystal should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. It is important to discuss the risks and benefits of taking this medication with your doctor.

Lactation Use

It is not known if nitrofurantoin passes into breast milk. Therefore, it should be used with caution in nursing mothers.

Acute Overdose

An overdose of nitrofurantoin can lead to serious side effects, including kidney damage and anemia. If you think you have taken too much of this medication, seek medical help immediately.

Contraindications

Nitrofurantoin Macrocrystal should not be used in people with certain conditions such as kidney disease, anemia, certain blood disorders, and allergies to nitrofurantoin or similar medications.

Use Directions

Nitrofurantoin Macrocrystal should be taken with plenty of fluids to prevent kidney stones forming and should be taken on an empty stomach, at least 2 hours after eating. It should be used for the full prescribed amount of time.

Storage Conditions

Nitrofurantoin Macrocrystal should be stored in a cool, dry place away from direct light or moisture. Keep the container tightly closed and away from children.

Volume of Distribution

Nitrofurantoin Macrocrystal has a volume of distribution of about 0.6-1 L/kg.

Half Life

The elimination half-life of nitrofurantoin is about 2-4 hours.

Clearance

The clearance of nitrofurantoin from the body is about 25-29 mL/min/kg.

Here you find in details version of Nitrofurantoin Macrocrystal

Some Frequently Asked Questions About Nitrofurantoin Macrocrystal

What is Nitrofurantoin Macrocrystal?

Nitrofurantoin Macrocrystal is an antibiotic medication prescribed to treat urinary tract infections. It works by killing the bacteria that causes the infection.

How does Nitrofurantoin Macrocrystal work?

Nitrofurantoin Macrocrystal works by killing the bacteria that causes the urinary tract infection. It is an antibacterial that inhibits the growth of bacteria by interfering with its cell wall synthesis.

What is the generic name for Nitrofurantoin Macrocrystal?

The generic name for Nitrofurantoin Macrocrystal is Nitrofurantoin Macrocrystal Mono/Macro.

Who should not take Nitrofurantoin Macrocrystal?

People with liver problems, kidney problems, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or those taking an antibiotic such as methenamine should not take Nitrofurantoin Macrocrystal.

What are the side effects of Nitrofurantoin Macrocrystal?

Side effects of Nitrofurantoin Macrocrystal can include nausea, vomiting, dizziness, fatigue, headache, abdominal pain, and diarrhea. Rare side effects may include an allergic reaction, yellowing of the skin or eyes, or a rash.

What is the recommended dosage for Nitrofurantoin Macrocrystal?

The recommended dosage for Nitrofurantoin Macrocrystal will vary depending on the age and weight of the patient, the type and severity of the infection, and other medical conditions. Follow your doctor's instructions for taking the medication.

Is Nitrofurantoin Macrocrystal safe?

Yes, Nitrofurantoin Macrocrystal is generally safe to take, but it is important to take it exactly as prescribed. Some people may experience side effects or an allergic reaction to the medication. Talk to your doctor if you have any concerns.

How long does it take for Nitrofurantoin Macrocrystal to work?

It typically takes about 1-3 days for Nitrofurantoin Macrocrystal to start working and approximately 7-14 days for the full effects to take place. If your symptoms do not improve after taking the medication for 7 days, call your doctor to discuss alternative treatment options.

Does Nitrofurantoin Macrocrystal treat all types of infections?

No, Nitrofurantoin Macrocrystal is specifically used to treat urinary tract infections. It will not work against viral infections such as colds or flu.

Does Nitrofurantoin Macrocrystal interact with other medications?

Yes, Nitrofurantoin Macrocrystal can interact with other medications. You should always tell your doctor about all of the other medications you are taking, including vitamins, over-the-counter medications, and herbal supplements.

What should I do if I miss a dose of Nitrofurantoin Macrocrystal?

If you miss a dose of Nitrofurantoin Macrocrystal, take the missed dosage as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

What is the most common complaint about Nitrofurantoin Macrocrystal?

The most common complaint about Nitrofurantoin Macrocrystal is gastrointestinal disturbances, such as nausea, vomiting, abdominal pain, and diarrhea.

Should I take Nitrofurantoin Macrocrystal with food?

Nitrofurantoin Macrocrystal can be taken with or without food. Taking the medication with food may help reduce the risk of gastrointestinal side effects.

Does Nitrofurantoin Macrocrystal have any long-term side effects?

Long-term side effects of Nitrofurantoin Macrocrystal are rare. However, it is possible that long-term use of the medication can cause liver or kidney damage. Be sure to talk to your doctor if you experience any unusual symptoms while taking Nitrofurantoin Macrocrystal.

What type of bacteria does Nitrofurantoin Macrocrystal treat?

Nitrofurantoin Macrocrystal is mainly used to treat infections caused by certain types of bacteria, such as Escherichia coli and Staphylococcus aureus.

What forms does Nitrofurantoin Macrocrystal come in?

Nitrofurantoin Macrocrystal is available in oral capsule, oral suspension, and oral tablet forms.

What should I do if I experience an allergic reaction while taking Nitrofurantoin Macrocrystal?

If you experience any signs of an allergic reaction while taking Nitrofurantoin Macrocrystal, such as hives, swelling, difficulty breathing, rapid heartbeat, or rash, stop taking the medication and call your doctor immediately.

Who manufactures Nitrofurantoin Macrocrystal?

Nitrofurantoin Macrocrystal is manufactured by several pharmaceutical companies, including Amneal Pharmaceuticals, Mylan Pharmaceuticals, Sandoz, and Teva Pharmaceuticals.

Can Nitrofurantoin Macrocrystal cause a yeast infection?

Yes, Nitrofurantoin Macrocrystal can cause a yeast infection. This is more likely to occur in people who are taking antibiotics for a long period of time. Symptoms of a yeast infection include itching, burning, or swelling in the genital or anal area.

Is Nitrofurantoin Macrocrystal an over-the-counter medication?

No, Nitrofurantoin Macrocrystal is only available with a prescription from your doctor.

How long should I take Nitrofurantoin Macrocrystal for?

The length of treatment with Nitrofurantoin Macrocrystal will depend on the type of infection being treated and other medical conditions. In most cases, it is recommended to take the medication for 7-14 days.

How long can I take Nitrofurantoin Macrocrystal?

There is no maximum recommended length of treatment with Nitrofurantoin Macrocrystal. However, your doctor may recommend that you take the medication for a certain period of time or until the infection is completely cleared.

Does Nitrofurantoin Macrocrystal have any drug interactions?

Yes, Nitrofurantoin Macrocrystal can interact with certain drugs. It is important to tell your doctor about all the other medications you are taking, including vitamins, over-the-counter medications, and herbal supplements.

Can Nitrofurantoin Macrocrystal be taken with food?

Yes, Nitrofurantoin Macrocrystal can be taken with food. Taking the medication with food may help reduce the risk of gastrointestinal side effects.

Is Nitrofurantoin Macrocrystal safe for pregnant women?

Yes, Nitrofurantoin Macrocrystal is generally safe for pregnant women. However, it is important to talk to your doctor if you are pregnant or planning to become pregnant. Your doctor can help you determine if it is safe for you to take Nitrofurantoin Macrocrystal.

Can Nitrofurantoin Macrocrystal cause blood in the urine?

Yes, it is possible that Nitrofurantoin Macrocrystal can cause blood in the urine. If you experience this side effect while taking the medication, contact your doctor.

Can Nitrofurantoin Macrocrystal be used for a bladder infection?

Yes, Nitrofurantoin Macrocrystal is commonly used to treat urinary tract infections, including bladder infections.

Is Nitrofurantoin Macrocrystal metabolized in the liver?

Yes, Nitrofurantoin Macrocrystal is metabolized in the liver. People with liver problems should not take Nitrofurantoin Macrocrystal.

Does Nitrofurantoin Macrocrystal need to be taken with water?

Yes, Nitrofurantoin Macrocrystal should always be taken with plenty of water. It is important to drink plenty of fluids while taking the medication to help reduce the risk of side effects.

Is Nitrofurantoin Macrocrystal safe for children?

Yes, Nitrofurantoin Macrocrystal can be used to treat urinary tract infections in children. However, the dosage and frequency should be determined by your doctor.

Does Nitrofurantoin Macrocrystal have an expiration date?

Yes, Nitrofurantoin Macrocrystal has an expiration date. Check the label on your medication for the expiration date and do not use the medicine after it has expired.

Does Nitrofurantoin Macrocrystal have any interactions with food?

No, Nitrofurantoin Macrocrystal does not have any interactions with food. However, it is important to take the medication as prescribed and not to miss any doses.

When should I start to feel better after taking Nitrofurantoin Macrocrystal?

It typically takes about 1-3 days for Nitrofurantoin Macrocrystal to start working and approximately 7-14 days for the full effects to take place. If your symptoms do not improve after taking the medication for 7 days, call your doctor.

Can Nitrofurantoin Macrocrystal be used to treat a kidney infection?

Yes, Nitrofurantoin Macrocrystal can be used to treat a kidney infection. It is important to take the medication as prescribed and to complete the full course of treatment in order to successfully treat the infection.

Can I take Nitrofurantoin Macrocrystal if I am allergic to penicillin?

Yes,Nitrofurantoin Macrocrystal can be taken if you are allergic to penicillin. However, you should talk to your doctor before taking this medication if you have any allergies or are taking any other medications.

Can you drink alcohol while taking Nitrofurantoin Macrocrystal?

It is not recommended to drink alcohol while taking Nitrofurantoin Macrocrystal. Alcohol can make the side effects of the medication worse and may interfere with its effectiveness.

Can Nitrofurantoin Macrocrystal cause constipation?

Yes, Nitrofurantoin Macrocrystal can cause constipation. If you experience constipation while taking the medication, talk to your doctor about ways to relieve the symptoms.

Is Nitrofurantoin Macrocrystal waterproof?

No, Nitrofurantoin Macrocrystal is not waterproof. It is important to take the medication as prescribed and to avoid any activities that could lead to the medication becoming wet or diluted.

What other medications can be used to treat a urinary tract infection?

Other antibiotics that can be used to treat urinary tract infections include ciprofloxacin, amoxicillin, and sulfamethoxazole. Your doctor will help you determine the best medication for your specific infection.

Can Nitrofurantoin Macrocrystal be taken with ibuprofen?

Yes, Nitrofurantoin Macrocrystal can be taken with ibuprofen. However, it is important to tell your doctor about all the other medications/supplements you are taking so that they can make sure there are no interactions between them.