Neomycin
Neomycin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Neomycin is a brand name. Its generic name is Neomycin.
Neomycin Introduction
Neomycin is an aminoglycoside antibiotic used to treat a variety of infections. It is used to kill a wide range of Gram-positive and Gram-negative bacteria. Neomycin belongs to the class of medicines called antibiotics. It works by killing the bacteria or preventing their growth.Uses for Neomycin
Neomycin is used to treat a variety of infections including:- Ear infections
- Respiratory tract infections
- Urinary tract infections
- Skin infections
- Gastrointestinal infections
- Bacterial infections
Mechanism of Action
Neomycin works by binding to bacterial ribosomes, blocking the synthesis of proteins needed for bacterial growth. It works best when coupled with other antibiotics to provide a synergistic effect.How Long Does It Take To Work?
It usually takes 1-2 days for Neomycin to start working. However, the full effects of the medication may take several days or weeks to show.Absorption
Neomycin is poorly absorbed when taken orally. It is more typically given by injection or topical application.Route of Elimination
Neomycin is eliminated through the urine and feces mostly in unchanged form.Dosage
Neomycin is available in tablet, capsule, injection, cream, ointment, and solution forms. Usual adult doses are as follows:- Tablets/Capsules: 250 mg to 1 g orally three times a day
- Injection: 20 mg to 1 g intramuscularly or intravenously once or twice a day
- Cream/Ointment: Apply one to two times a day
- Solution: 1-2 mL intramuscularly or intravenously three times a day
Administration
Neomycin may be administered orally, intramuscularly, intravenously, or topically.Side Effects
Common side effects of Neomycin include:- Nausea
- Vomiting
- Diarrhea
- Rash
- Itching
- Deafness
- Dizziness
- Headache
- Confusion
Toxicity
Neomycin is generally safe when used as directed. However, overdoses can cause serious harm and can even be fatal.Precaution
Neomycin should be used with caution in patients with renal impairment, as it can accumulate in the body and cause further damage to the kidneys. It should also be used with caution in patients with hearing impairment or those taking other medications that may also cause hearing problems.Interaction
Neomycin may interact with other medications, such as sulfonamides, amphotericin B, cyclosporine, vancomycin, and probenecid. These interactions can increase the risk of hearing loss, kidney damage, and other serious side effects.Disease Interaction
Neomycin may interact with certain diseases, such as myasthenia gravis, hepatic impairment, and Addison’s disease. It is important to be aware of any potential interactions.Drug Interaction
Neomycin may interact with other drugs, such as antacids, aminoglycosides, corticosteroids, phenazopyridine, and some calcium channel blockers.Food Interaction
There are no known food interactions with neomycin.Pregnancy Use
Neomycin is considered safe for use in pregnancy. However, the risks and benefits of taking any medication during pregnancy should be discussed with your doctor.Lactation Use
Neomycin is best avoided during lactation.Acute Overdose
If an overdose of neomycin is suspected seek medical attention immediately. Overdoses of neomycin can lead to severe side effects such as dizziness, confusion, and hearing loss.Contraindication
Neomycin is contraindicated in patients with a history of hypersensitivity to it or other aminoglycoside antibiotics.Use Direction
Neomycin should only be used as prescribed by a qualified medical professional. The prescriber should provide instructions on how to use the medication safely and effectively.Storage Condition
Neomycin should be stored at room temperature away from direct light and moisture.Volume of Distribution
Neomycin has a volume of distribution of 0.5-1 L/kg of body weight.Half Life
The half life of neomycin is 1.5-2 hours.Clearance
The clearance of neomycin is 0.07-0.24 mL/min/kg.Here you find in details version of Neomycin
Some Frequently Asked Questions About Neomycin
What is neomycin?
Neomycin is an antibiotic that is used to treat a variety of bacterial infections. It works by stopping the growth of bacteria.
What conditions are treated with neomycin?
Neomycin is used to treat a range of bacterial infections, including urinary tract infections, skin infections, eye infections, and some ear infections.
What are the side effects of neomycin?
The most common side effects of neomycin are dizziness, nausea, vomiting, and diarrhea. Other more serious side effects include allergic reactions, kidney damage, hearing loss, and seizures.
Who should not take neomycin?
Neomycin should not be used by people with known allergies to the drug. It should also not be used by people with kidney disease or a history of kidney stones. People with a history of hearing loss should also avoid use of neomycin.
How long does it take for neomycin to work?
It typically takes several days to a week for neomycin to start to work. However, the exact timeframe can vary depending on the type and severity of the infection.
Is neomycin safe to take during pregnancy?
Neomycin is generally not recommended during pregnancy, as it can cause harm to a developing fetus. It should only be used if the potential benefits outweigh the risks.
How is neomycin administered?
Neomycin is available as a topical cream, ointment, or solution, as well as an oral tablet or suspension. It can also be given intravenously.
What drug class is neomycin?
Neomycin is an aminoglycoside antibiotic.
How often should neomycin be taken?
The exact dosing instructions depend on the type of infection being treated, so it is important to follow your doctor’s instructions carefully. Generally, neomycin is taken two to four times daily.
What are the common brand names for neomycin?
Neosporin, Mycifradin, NeoFradin, and Neo-Fradin are common brand names for neomycin.
Is neomycin available over-the-counter?
Neomycin products are available over-the-counter in some countries, but in the United States neomycin products require a prescription from a doctor.
Is neomycin safe for cats?
Neomycin is generally not used in cats due to the risk of causing hearing loss. Your veterinarian can recommend an alternate form of treatment tailored to your cat’s specific needs.
How long does neomycin stay in the body?
The elimination half-life of neomycin in adults is 8-9 hours, with most of it being excreted in the urine. It typically takes several days to a week for the drug to be completely eliminated from the body.
Can neomycin be taken with other medications?
Neomycin should be taken with caution when taken with other medications, as it can interact with a wide range of drugs. It is important to inform your doctor of all medications you are taking before starting neomycin.
Can neomycin be used to treat a sinus infection?
Neomycin is not typically used to treat sinus infections as it is not as effective against certain bacteria commonly found in sinus infections.
Can neomycin be used to treat MRSA?
Neomycin is not typically used to treat MRSA due to the risk of developing resistance. Other antibiotics, such as trimethoprim-sulfamethoxazole, linezolid, and clindamycin, may be more effective for treating MRSA.
Can neomycin be used to treat pneumonia?
Neomycin is not typically used to treat pneumonia due to the risk of developing resistance. Other antibiotics, such as amoxicillin, cefaclor, cefdinir, and cefpodoxime, may be more effective for treating pneumonia.
What is the dosage of neomycin for adults?
The usual adult dosage of neomycin is 2-3 g/day in divided doses every 6-8 hours, depending on the severity of the infection. However, the exact dosage should be determined by a doctor depending on the type of infection and the patient's other medical conditions.
What is the dosage of neomycin for children?
For children younger than 12 years old, the recommended dosage of neomycin is 30-40mg/kg/day in divided doses every 6-8 hours. As with adults, the exact dosage should be determined by a doctor depending on the type of infection and the patient's other medical conditions.
What should I do if I miss a dose of neomycin?
If you miss a dose of neomycin, take it as soon as you remember and then continue your regular dosing schedule. Do not double up on doses, as this can increase the risk of side effects.
What should I do if I overdose on neomycin?
If you think you may have overdosed on neomycin, contact your local poison control center or seek emergency medical attention immediately.
Can neomycin cause hearing loss?
Neomycin can cause irreversible hearing loss in some people, particularly those with kidney disease or a history of kidney stones. For this reason, neomycin should be used with caution and only if the potential benefits outweigh the risks.
Can neomycin cause kidney damage?
Neomycin can cause kidney damage in some people, particularly those with kidney disease or a history of kidney stones. For this reason, neomycin should be used with caution and only if the potential benefits outweigh the risks.
Can neomycin be used for long-term treatment?
While neomycin can be used for long-term treatment, it should not be used for more than 14 days. Long-term use of neomycin can increase the risk of side effects, particularly hearing loss.
Can I drink alcohol while taking neomycin?
It is not advised to drink alcohol while taking neomycin, as it can increase the risk of experiencing side effects and may increase the risk of developing hearing loss.
What are the common side effects of topical neomycin?
The most common side effects of topical neomycin are redness, itching, stinging, and burning. More serious side effects can include anaphylaxis, kidney damage, and hearing loss.
What is the shelf life of neomycin?
The shelf life of neomycin depends on the form of the drug. Neomycin tablets and suspensions are typically stable for 3 years from the date of manufacture, while the shelf life of neomycin ointments and creams is typically 18 months.
Can neomycin be used to treat a bladder infection?
Yes, neomycin can be used to treat a bladder infection. It is generally used in combination with other antibiotics, such as trimethoprim or nitrofurantoin, to improve its effectiveness.
Can neomycin be used to treat a yeast infection?
No, neomycin is not effective at treating yeast infections. Other antifungal medications, such as fluconazole or clotrimazole, are more effective for treating yeast infections.
Can neomycin be used to treat bronchitis?
Neomycin is generally not used to treat bronchitis, as it is not effective against some of the bacteria that are known to cause bronchitis. Those with acute bronchitis should see their health care provider to determine the best course of treatment.
Can I take neomycin with ibuprofen?
Yes, you can take neomycin with ibuprofen. However, this combination can increase the risk of side effects, such as stomach upset or bleeding. It is important to let your doctor know if you are taking any other medications before taking neomycin.
Is neomycin effective against staph infections?
Neomycin can be effective against some types of staph infections, but it may not be as effective against all strains of staph bacteria. Your doctor can recommend an antibiotic that is more effective against your particular strain of staph infection.
Can neomycin cause an allergic reaction?
Yes, neomycin can cause an allergic reaction in some people, and the reactions can range from mild to severe. Symptoms of an allergic reaction include hives, itching, swelling, difficulty breathing, and chest tightness.
What should I do if I experience an allergic reaction to neomycin?
If you experience an allergic reaction while taking neomycin, stop taking the medication and contact your doctor or seek emergency medical attention immediately.
Can neomycin be used to treat strep throat?
Neomycin is not typically used to treat strep throat, as it is not very effective against the bacteria that cause strep throat. Your doctor can recommend a more suitable treatment option.
How long does it take to recover from a neomycin infection?
The time it takes to recover from a neomycin infection depends on the type and severity of the infection. In general, most infections should begin to show signs of improvement within a few days of starting treatment. It is important to finish the entire course of neomycin to ensure a full recovery.
Are there any drug interactions with neomycin?
Yes, neomycin can interact with a wide range of medications. It is important to let your doctor know about all medications you are currently taking before starting treatment with neomycin.
Is neomycin FDA approved?
Yes, neomycin is FDA approved for use in treating certain bacterial infections. However, it is important to follow your doctor’s advice when using any medication.
Can neomycin cause permanent hearing loss?
Neomycin can cause permanent hearing loss in some people, particularly those with kidney disease or a history of kidney stones. For this reason, neomycin should be used with caution and only if the potential benefits outweigh the risks.