Nebita

Nebita Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nebita is a brand name. Its generic name is Nebivolol.

Nebita

Nebita is an antihypertensive medicine which belongs to the beta-blocking class of drugs. It is mainly used to treat hypertension (high blood pressure). It works by blocking a hormone in the body called noradrenaline (norepinephrine), thus reducing heart rate and the force of heart muscle contraction, resulting in a decrease in heart pressure.

Uses for

Nebita is primarily indicated to treat mild to moderate high blood pressure (hypertension). It may also be indicated for the following conditions:

• Angina (chest pain)
• Congestive heart failure
• Atrial fibrillation
• Coronary artery disease

Mechanism of Action

Nebita works by blocking the action of the hormone noradrenaline (norepinephrine). By blocking the action of noradrenaline onBeta-1 receptors in the heart, Nebita reduces the force of muscle contraction in the heart and also reduces the heart rate. This results in the reduction of heart pressure and gives relief from hypertension.

How Long Does It Take to Work?

Nebita works quickly and the effects can be seen within an hour of taking the medicine. However, it usually takes about 4 weeks for the full effects to be seen. This is generally the time frame necessary for the medicine to reach the therapeutic levels in the body.

Absorption

Nebita is readily absorbed from the gastrointestinal tract. The peak plasma concentration is usually reached within 1-2 hours after an oral dose.

Route of Elimination

Nebita is mainly eliminated through the urine and/or feces. Around 15-20% of the administered dose is excreted through the urine as unchanged drug.

Dosage

The recommended dosage for treating hypertension is 5-20 mg taken once daily. The dosage may be increased gradually as per the doctor’s instructions. It is important to take the dose regularly and at the same time each day for the best effect.

Administration

Nebita should be taken orally with or without food. The tablet should not be chewed or crushed as this may reduce the effectiveness. It is also important to follow the doctor’s instructions and advice as different people may need different doses to get the desired effect.

Side Effect

Nebita may cause side effects in some people. The most common side effects are fatigue, headaches, dizziness, and dry mouth. Less common side effects include nausea, vomiting, diarrhoea, and skin rashes. If these side effects persist or worsen, contact your doctor.

Toxicity

Nebita is generally safe and well tolerated. However, overdosage may cause symptoms such as hypotension (low blood pressure), bradycardia (slow heart rate), and coma. In the event of an overdose, seek medical attention immediately.

Precautions

• Nebita should be used with caution in elderly patients, as it may increase the risk of falls and fractures.
• The use of Nebita in pregnant women is not recommended as it may cause fetal harm.
• Nebita should be used with caution in patients with asthma or other breathing problems, since it may cause difficulty breathing.
• People with kidney or liver disease should consult their doctor before using Nebita.

Interaction

Nebita may interact with other medicines, herbs, vitamins, minerals, or dietary supplements, so it is important to inform your doctor about any medicines you may be taking. Also, certain drugs may interfere with how Nebita works, so contact your doctor if you are taking any of the following:

• MAO inhibitors (e.g. isocarboxazid, phenelzine, tranylcypromine, etc.)
• Beta-blockers (e.g. propranolol, atenolol, metoprolol, etc.)
• Angiotensin-converting enzyme (ACE) inhibitors (e.g. benazepril, enalapril, lisinopril, etc.)
• Calcium channel blockers (e.g. diltiazem, verapamil, etc.)
• Tricyclic antidepressants (e.g. amitriptyline, nortriptyline, etc.)

Disease Interaction

Nebita may interact with certain diseases, so it is important to inform your doctor about any conditions you have. People with asthma, heart block, bradycardia, heart failure, or certain other diseases should use this medicine cautiously and with close monitoring.

Drug Interaction

Nebita may interact with certain drugs, so it is important to inform your doctor about any medications you may be taking. Also, some drugs may interfere with the way Nebita works, so contact your doctor if you are taking any of the following: Tricyclic antidepressants, antipsychotic drugs, anti-seizure drugs, anti-anxiety medicines, beta-blockers, and calcium channel blockers.

Food Interactions

Nebita is not known to interact with food. However, it is best to take Nebita at the same time each day, preferably after food.

Pregnancy Use

Nebita should not be used in pregnant women, as it may cause harm to the fetus. It is best to consult your doctor before taking this medicine during pregnancy.

Lactation Use

Nebita should not be used while breastfeeding, as it may pass into the breast milk and affect the baby. It is best to consult your doctor before taking this medicine while breastfeeding.

Acute Overdose

In cases of an acute overdose, symptomatic treatment should be given and medical attention should be sought immediately. Symptoms of an overdose may include hypotension (low blood pressure), bradycardia (slow heart rate), and coma.

Contraindication

Nebita should not be used in people with allergy or hypersensitivity to the active ingredient, or with certain conditions such as asthma, heart block, bradycardia, heart failure, or uncontrolled severe hypertension.

Use Directions

Nebita should be taken orally as prescribed. The usual starting dose is 5-20 mg taken once daily, usually at the same time each day. The dosage may be adjusted as per your doctor’s instructions. It is important to take the dose regularly and at the same time each day for the best effect.

Storage Conditions

Nebita should be stored at room temperature and protected from light and moisture. It should also be kept out of the reach of children and pets.

Volume of Distribution

Nebita has an estimated volume of distribution of about 3.6L/Kg.

Half Life

The elimination half-life of Nebita is about 10 hours.

Clearance

Nebita has an estimated clearance rate of about 5.3L/hr/Kg.

Here you find in details version of Nebita

Some Frequently Asked Questions About Nebita

What is Nebita?

Nebita is a selective beta-1 receptor blocker and vasodilator drug used to treat high blood pressure and left ventricular dysfunction.

What is Nebita used for?

Nebita is used to treat high blood pressure and left ventricular dysfunction. It is also used off label to treat chest pain and migraine prevention.

What is the mechanism of action of Nebita?

Nebita works by blocking beta-1 adrenergic receptors in the heart, which decreases heart rate, reduces the amount of blood pumped from the heart, and lowers the force of contraction of the heart muscle. It also constricts blood vessels, which reduces blood pressure.

How long does Nebita take to work?

Nebita can start working as soon as 30 minutes after it is taken, however, the full effects may not be seen for several weeks.

Is Nebita a controlled substance?

No, Nebita is not a controlled substance.

Is Nebita safe?

Yes, Nebita is generally safe when taken as prescribed. However, like all medications, Nebita may cause side effects in some patients.

What are the side effects of Nebita?

Common side effects of Nebita include headache, fatigue, dizziness, low blood pressure, and nausea. More serious side effects of Nebita may include shortness of breath, chest pain, irregular heartbeat, and swelling of the ankles or feet.

Can I take Nebita while pregnant?

If you are pregnant or planning to become pregnant, you should consult with your doctor before taking Nebita. It is not known if Nebita is safe for use during pregnancy.

Can I take Nebita while breastfeeding?

You should consult with your doctor before taking Nebita while breastfeeding. It is not known if Nebita is safe for use while breastfeeding.

Does Nebita interact with any other medications?

Yes, Nebita may interact with other medications, including blood pressure medications, cholesterol medications, and certain antibiotics. You should always tell your healthcare provider about all other medications you are taking before starting Nebita.

Can I split Nebita tablets?

It is best to consult with your doctor or pharmacist before splitting Nebita tablets, as some tablets may be too small or fragile to accurately split.

When should I take Nebita?

Nebita is usually taken once daily, in the morning. It is important to take it at the same time each day and to follow all instructions on how to take Nebita.

What should I do if I miss a dose of Nebita?

If you miss a dose of Nebita, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

What should I do if I overdose on Nebita?

If you think you may have overdosed on Nebita, contact your local poison control center or emergency room right away.

What are the storage requirements for Nebita?

Nebita tablets should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

How long does Nebita stay in my system?

Nebita is usually cleared from the system within 24 hours, however, it may take longer in some individuals.

Can I drink alcohol while taking Nebita?

It is not recommended to drink alcohol while taking Nebita, as it can increase the risk of side effects.

Will Nebita lower my blood pressure too much?

Nebita is generally effective at lowering blood pressure. However, it is important to follow your doctor's instructions closely, as too much of a decrease in blood pressure can cause serious side effects.

Can I take Nebita with other blood pressure medications?

Yes, your doctor may prescribe Nebita in combination with other blood pressure medications. It is important to take all medications as prescribed and to inform your doctor of any side effects.

What are the differences between Nebita and other beta blockers?

Nebita is a selective beta-1 receptor blocker, meaning it blocks beta-1 receptors in the heart, while having less of an effect on other areas of the body. Other beta blockers may be non-selective, meaning they can block beta-1 and beta-2 receptors in the body.

Is Nebita effective for reducing the risk of heart disease?

Nebita may reduce the risk of death and heart attack in people with heart failure, particularly when taken in combination with other medications. Nebita is also used to reduce the risk of stroke and sudden death in people who have already had a heart attack.

Can I exercise while taking Nebita?

Yes, you can exercise while taking Nebita. However, you should discuss any regular exercise program with your doctor before starting it. Be sure to drink plenty of water while exercising and take breaks if needed.

What are the long-term effects of taking Nebita?

Nebita is generally well tolerated and the long-term effects are positive. Nebita has been found to reduce the risk of stroke, heart attack, and sudden death in people with heart failure.

Does Nebita cause weight gain?

Weight gain is not a common side effect of Nebita. However, some people do report gaining a small amount of weight while taking Nebita.

Can I take Nebita if I have asthma or COPD?

Nebita is not recommended for people with asthma or COPD. It is important to tell your doctor about all medical conditions before taking Nebita.

Is Nebita available as a generic drug?

Yes, Nebita is available as a generic drug.

What is the cost of Nebita?

The cost of Nebita depends on the dosage, the form, and the pharmacy. A generic version of Nebita is typically cheaper than the brand-name version.

Does Nebita cause frequent urination?

No, Nebita does not typically cause frequent urination. However, some people may experience side effects such as frequent urination or increased thirst while taking Nebita.

Does Nebita have anticoagulant properties?

No, Nebita does not have anticoagulant properties. People taking blood thinning medications such as warfarin should not take Nebita.

Can I take an antihistamine with Nebita?

Yes, most antihistamines are safe to take with Nebita. Be sure to tell your doctor about all medications, supplements, and vitamins you are taking before starting Nebita.

Can I take Nebita if I have diabetes?

Yes, Nebita is generally safe for people with diabetes. However, it is important to tell your doctor about any history of diabetes before taking Nebita.

What are the signs of an allergic reaction to Nebita?

Signs of an allergic reaction to Nebita may include difficulty breathing, rash, hives, swelling of the face or tongue, itching, or tightness in the chest. If you experience any of these symptoms, contact your healthcare provider immediately.

Can I take Nebita with vitamins or supplements?

Yes, but it is important to tell your doctor about any vitamins or supplements you are taking before starting Nebita. Some vitamins or supplements may interact with Nebita.

Can I take over-the-counter medications with Nebita?

Yes, it is generally safe to take over-the-counter medications with Nebita. However, it is important to tell your doctor about any over-the-counter medications you are taking before starting Nebita.

What is the difference between Nebita and other beta-blockers?

Nebita is a selective beta-1 receptor blocker, meaning it blocks beta-1 receptors in the heart, while having less of an effect on other areas of the body. Other beta-blockers may be non-selective, meaning they can block beta-1 and beta-2 receptors in the body.

What should I do if I experience side effects while taking Nebita?

If you experience side effects while taking Nebita, contact your doctor or healthcare provider right away. They may be able to adjust your dose or suggest other treatments to help alleviate the side effects.

Can I stop taking Nebita without consulting my doctor?

No, it is important to always talk to your doctor before stopping or changing your dose of Nebita. If you suddenly stop or reduce your Nebita dose, it may cause serious heart problems or even death.

Can elderly patients take Nebita?

Yes, Nebita is generally safe for elderly patients when taken as directed. However, your doctor may adjust your dose to account for any age-related physical changes. Be sure to visit your doctor regularly while taking Nebita.

Does Nebita cause dry eyes?

No, dry eyes is not a common side effect of Nebita. If you experience dry eyes while taking Nebita, contact your doctor.

Q Does Nebita interact with grapefruit or grapefruit juice?

Yes, Nebita may interact with grapefruit or grapefruit juice. It is important to discuss any dietary changes with your doctor before taking Nebita.