Tilade
Tilade Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tilade is a brand name. Its generic name is Nedocromil.
Tilade
Tilade (also known as Tilade) is a medication used to treat asthma and other respiratory conditions. It is a long-acting anti-inflammatory agent that helps reduce airway inflammation and mucus production by inhibiting the release of certain chemicals in the body. Tilade is typically prescribed as an inhaler or nasal spray.
Uses for Tilade
Tilade is used to treat mild to moderate asthma attacks. It can also help prevent repetitive or more serious asthma attacks when taken regularly. This medication can also be used to treat childhood asthma and allergic rhinitis (hay fever).
Mechanism of Action
Tilade works by blocking the release of chemicals that normally cause inflammation in the airways. This prevents asthma and other respiratory conditions from worsening. When taken regularly, Tilade can also help prevent asthma attacks before they start.
How Long Does it Take to Work?
Tilade usually takes effect within 5-20 minutes of being inhaled or used. However, it can take up to 2 hours for the full effects to be felt. The effects of Tilade can last up to 12 hours.
Absorption
Tilade is well absorbed after inhalation and may reach maximum concentrations in serum within 2 hours. It is also quickly absorbed through the nose after nasal spray administration. After an inhalation, about 35% of the total dose reaches the systemic circulation.
Route of Elimination
Tilade is eliminated mainly through the kidneys. After absorption, it is metabolized and converted into inactive metabolites, which are then eliminated through urination.
Dosage
The usual dose of Tilade is 2 milligrams (mg) twice daily via inhaler or nasal spray. The dose for children is usually lower, and should only be taken under the supervision of a physician. An inhaler should be used one inhalation at a time, while the nasal spray should only be used once each day.
Administration
Tilade is usually taken by inhaler or nasal spray twice per day. For inhaler use, a metered-dose inhaler is recommended to ensure the accurate delivery of the medication. For nasal spray use, the medication should be administered one spray in each nostril once daily.
Side Effects
Common side effects of Tilade include burning and stinging of the nose or throat; sneezing; a dry mouth; coughing; headache; and an upset stomach. More serious side effects may include severe allergic reactions and difficulty breathing.
Toxicity
Tilade is generally well tolerated, with no reported cases of toxicities from oral or inhalational overdose. In rare cases, excessive use of inhalers or nasal sprays can cause bronchospasm in individuals with underlying lung disease.
Precautions
Before beginning Tilade, patients should inform their doctor of any medical allergies, other medications they are taking, and any other illnesses they may have. In particular, patients with an allergy to aspirin should not take Tilade. Because Tilade can cause dizziness or drowsiness, patients should avoid driving or operating heavy machinery until the medication’s effects are known.
Interactions
Tilade may interact with other medications including corticosteroids, blood thinners, diuretics, and beta blockers. It may also interact with certain foods and beverages. Therefore, it is important to advise a doctor of any other medications or supplements being taken before trying Tilade.
Disease Interactions
Tilade should be used with caution, or avoided in patients with certain medical conditions such as bronchitis, COPD, asthma, and other respiratory illnesses. It also should not be given to patients who are pregnant or breastfeeding.
Drug Interactions
Tilade may interact with other medications including corticosteroids, blood thinners, diuretics, and beta blockers. It is important to inform a doctor of any other medications or supplements being taken before trying Tilade.
Food Interactions
Tilade may interact with certain foods and beverages, including acidic foods, dairy products, and citrus fruits. Therefore, it is important to avoid any of these items while on the medication.
Pregnancy Use
Tilade is not recommended during pregnancy and should not be used without prior approval from a healthcare professional.
Lactation Use
Tilade should not be used by people who are breastfeeding. If the medication is necessary, the benefits should be weighed against the potential risks before taking it.
Acute Overdose
An acute overdose of Tilade is unlikely to cause severe consequences; however, those who knowingly overdose on the medication should seek medical attention immediately.
Contraindications
Tilade is contraindicated in patients with an allergy to aspirin, bronchitis, COPD, asthma, or other respiratory illnesses. It should not be used by pregnant or breastfeeding women without prior approval from a healthcare professional.
Use Directions
Tilade should be used according to the instructions given by the physician. For inhalation, use a metered-dose inhaler one inhalation at a time. For nasal spray use, one spray in each nostril once daily. Do not exceed the recommended dose.
Storage Conditions
Tilade should be kept at room temperature and should be stored away from heat and moisture. The medication should be kept out of the reach of children and should not be shared with others.
Volume of Distribution
Tilade is not well distributed throughout the body. After absorption, it mainly resides in the lungs, where it exerts its anti-inflammatory effects.
Half Life
The half-life of Tilade is about 2.7 hours.
Clearance
Tilade is primarily eliminated through the kidneys. After absorption, it is metabolized and converted into inactive metabolites, which are then excreted by the body in urine.
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