Navafil
Navafil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Navafil is a brand name. Its generic name is Avanafil.
Navafil Introduction
Navafil is an oral drug used for the treatment of erectile dysfunction (ED). It belongs to the class of medications called phosphodiesterase-5 (PDE5) inhibitors. This drug helps to improve erectile dysfunction by allowing the muscles of the blood vessels of the penis to relax, allowing an increased flow of blood.Uses For Navafil
Navafil is used for treating erectile dysfunction (ED). It is also used for treatment of impotence in men.Mechanism of Action
Navafil works by inhibiting phosphodiesterase-5 (PDE5) enzyme, which helps to relax the blood vessels in the penis. This helps to improve blood flow in the penis, leading to better and firmer erections.How Long Does it Take to Work?
Navafil starts to work about 10 minutes after taking it. Its effects last up to 6 hours, allowing increased blood flow and improved erections.Absorption
Navafil is rapidly absorbed after oral administration. Its peak plasma concentration is achieved within 45 minutes.Route of Elimination
Navafil is excreted mainly through urine. Small amounts are also eliminated in the feces.Dosage
The recommended starting dosage of Navafil is 50 mg, taken about 30 minutes prior to sexual activity. Depending on how well the drug works and the individual response, the dosage can be increased up to 200 mg or decreased to 25 mg. Patients with severe renal or hepatic impairment, should take the initial dose of 25 mg. It is important to take the drug only as prescribed by the doctor.Administration
Navafil is administered orally about 30 minutes prior to sexual activity. It can be taken with or without food.Side Effects
Common side effects of Navafil include headache, nasal congestion, flushing, dizziness, upset stomach, and visual disturbances. It can also cause hypotension (low blood pressure) and priapism (a prolonged and painful erection).Toxicity
Navafil is generally well tolerated with few side effects reported. However, in some cases, it can cause serious toxicities such as hypotension (low blood pressure), dizziness, and priapism (prolonged and painful erection).Precautions
It is important to talk to your doctor before taking Navafil if you have any of the following conditions: heart or blood pressure problems, kidney or liver disease, low blood pressure, bleeding disorders, or any allergies.Interaction
Navafil may interact with certain drugs, including nitrates, alpha blockers, and protease inhibitors. Therefore, it is important to discuss all medications taken with the doctor before taking Navafil.Disease Interaction
Navafil may interact with certain diseases, such as kidney or liver disease, low blood pressure, and bleeding disorders. It is important to discuss all medical conditions with the doctor before taking Navafil.Drug Interaction
Navafil may interact with certain drugs, including nitrates, alpha blockers, and protease inhibitors. Therefore, it is important to discuss all medications taken with the doctor before taking Navafil.Food Interactions
Navafil should not be taken together with a fatty meal as it may delay the absorption. It is best to take the medication after a light meal.Pregnancy Use
Navafil should not be used during pregnancy unless the benefits outweigh the risks. It is important to discuss this with the doctor.Lactation Use
Navafil should be used with caution in lactating women as it may cause harm to the nursing infant. It is important to discuss this with the doctor.Acute Overdose
Acute overdose of Navafil can cause serious adverse effects like dizziness, fainting, flushing, low blood pressure, priapism, nausea and/or vomiting.Contraindication
Navafil is contraindicated in patients with known hypersensitivity to any of its components. In addition, it should not be used in patients with a history of stroke or heart attack, liver or kidney disease, or other certain medical conditions.Use Direction
Navafil should be taken as directed by the doctor. The recommended starting dosage is 50 mg, taken 30 minutes prior to sexual activity. The dosage may be increased or decreased depending on individual response. It is important to take the drug only as prescribed by the doctor.Storage Conditions
Navafil should be stored at room temperature away from light and moisture.Volume Of Distribution
Navafil has a mean volume of distribution of about 130 L.Half Life
Navafil has a mean elimination half-life of about 5 hours.Clearance
The mean total body clearance of Navafil is about 113 L/h.Here you find in details version of Navafil
Some Frequently Asked Questions About Navafil
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