Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom)

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) is a brand name. Its generic name is Mepyramine + Pamabrom + Acetaminophen.

Introduction

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) is a combination of three medications used to treat conditions such as nausea, vomiting, headache, muscle aches, and fever. The three components of the combination are mepyramine, pamabrom, and acetaminophen.

Uses

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) is used to relieve pain, reduce fever and treat symptoms of certain medical conditions, including nausea, vomiting, headache, muscle aches, and fever.

Mechanism of Action

Mepyramine works by blocking the action of histamine in the body. Pamabrom is a diuretic that relieves fluid retention and reduces bloating. Acetaminophen relieves pain and reduces fever.

How Long Does it Take to Work?

The effects of Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) may occur within minutes after administration.

Absorption

Mepyramine is rapidly absorbed from the gastrointestinal tract and is quickly distributed throughout the body. Pamabrom is also rapidly absorbed in the gastrointestinal tract. Acetaminophen is rapidly and extensively absorbed from the gastrointestinal tract.

Route of Elimination

Mepyramine is mainly eliminated via the kidneys. Pamabrom is eliminated primarily through the urine. Acetaminophen is primarily metabolized by the liver and is mainly excreted in the urine.

Dosage

Mepyramine and Pamabrom should be taken orally as directed by a healthcare provider. The usual adult dose of Mepyramine is 25 to 100 mg orally every 6 hours as needed. The usual adult dose of Pamabrom is 25 to 100 mg orally every 8 to 12 hours as needed. Acetaminophen should be taken orally as directed. The usual adult dose for Acetaminophen is 650 to 1000 mg orally every 4 to 6 hours as needed.

Administration

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be taken orally as directed by a healthcare provider. Mepyramine and Pamabrom should be taken with a full glass of water. Acetaminophen may be taken with or without food.

Side Effects

Common side effects of Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) include headache, dizziness, drowsiness, nausea, vomiting, and constipation. If these side effects persist or worsen, contact your healthcare provider.

Toxicity

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) can be toxic if taken in excessive doses. Overdose of mepyramine can cause seizures, dizziness, heart palpitations, headache, gastrointestinal distress, and coma. Overdose of pamabrom may cause dehydration, dizziness, and sweating. Acetaminophen can cause liver damage and may be fatal if taken in large doses.

Precaution

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be used with caution in patients with kidney or liver disease, high blood pressure, and heart disease. Mepyramine and Pamabrom may cause drowsiness and may impair the ability to drive or operate machinery.

Interaction

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should not be taken with other medications that can cause drowsiness, such as sedatives or alcohol.

Disease Interaction

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) may interact with certain medical conditions. Therefore, it is important to discuss your medical history with your healthcare provider before taking this medication.

Drug Interactions

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) may interact with other medications, including anticoagulants, sedatives, alcohol, muscle relaxants, depressants, or stimulants.

Food Interactions

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be taken with a full glass of water and may be taken with or without food. Certain foods, such as dairy products, may decrease the absorption of Mepyramine.

Pregnancy Use

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be used with caution in pregnant women due to the potential for birth defects and other serious side effects. Consult your healthcare provider before taking this medication during pregnancy.

Lactation Use

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be avoided in nursing mothers due to the potential for serious side effects.

Acute Overdose

If an acute overdose is suspected, immediate medical treatment should be sought. Symptoms of an overdose may include seizures, dizziness, vomiting, abdominal pain, and coma.

Contraindication

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should not be taken if you are allergic to any of the ingredients or if you have certain medical conditions such as glaucoma, asthma, porphyria, or liver or kidney disease.

Use Direction

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be taken as directed by a healthcare provider. Do not take more than the recommended dose or for a longer period of time than prescribed.

Storage Condition

Midol PMS Complete (Acetaminophen,Mepyramine,Pamabrom) should be stored at room temperature in a light-resistant, childproof container.

Volume of Distribution

Mepyramine has a volume of distribution of approximately 0.3–2 L/kg. The volume of distribution of pamabrom is 0.2–0.5 L/kg, while the volume of distribution of acetaminophen is 0.8–1.2 L/kg.

Half Life

The half life of mepyramine is 2.3–3.2 hours, while the half life of pamabrom is 1.6–2.2 hours. The halflife of acetaminophen is 1.25–3 hours.

Clearance

Mepyramine has a clearance rate of 0.04–0.09 L/h/kg, while pamabrom has a clearance rate of 0.02–0.05 L/h/kg. The clearance rate of acetaminophen is 0.5–1.0 L/h/kg.

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