Loxitane
Loxitane Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Loxitane is a brand name. Its generic name is Loxapine.
## Introduction Loxitane is an antipsychotic medication disapproved for treating schizophrenia and other psychological disorders. It is also used for controlling aggressive behavior in patients with mental illness or dementia. It works by changing the effects of certain natural substances in the brain and decreasing psychotic thinking and behavior. ## Uses Loxitane is used to treat schizophrenia, to control aggressive behavior that is associated with mental illness or dementia, and to treat severe behavior and thought problems in patients with mental illness. ## Mechanism of Action Loxitane is an antipsychotic medication that is thought to work by altering the balance of chemicals in the brain that are associated with psychotic thinking and behavior. It blocks the effect of dopamine and serotonin and thus changes the action of these hormones. This helps to control the thinking and behavior of the patient and reduces the severity or frequency of symptoms. ## How Long Does It Take to Work? Loxitane can begin to work quickly. It usually takes about 4-6 weeks for the full effects to be seen. ## Absorption Loxitane is absorbed from the gastrointestinal tract and is widely distributed throughout the body. ## Route of Elimination Loxitane is eliminated primarily through the kidney. ## Dosage The recommended adult dose of loxapine is usually between 10 and 40 mg taken daily. Dosage may be adjusted as needed. ## Administration Loxitane is available as a tablet or oral solution. It should be taken with food to reduce stomach upset. ## Side Effects The most common side effects of loxapine include dry mouth, sedation, restlessness, constipation, weight gain, and dizziness. ## Toxicity Loxitane is not considered to be toxic. Overdose can cause serious symptoms such as drowsiness, agitation, confusion, and seizures. ## Precautions Patients taking loxapine should be monitored for changes in blood pressure, heart rate, and urinary output. Patients with a history of cardiovascular or cerebrovascular disease or bipolar disorder should be monitored more closely. ## Interactions Loxitane may interact with other medications, including antidepressants, antipsychotics, antihistamines, and anticonvulsants. It is important to tell a healthcare provider about all medications being taken prior to starting loxapine. ## Disease Interactions Loxitane may interact with certain disease states such as cardiovascular or cerebrovascular disease, bleeding disorders, hypothyroidism, and renal failure. Patients with these conditions should be monitored closely. ## Drug Interactions Loxitane may interact with other drugs such as antidepressants, antipsychotics, antihistamines, or anticonvulsants. It is important to tell a healthcare provider about all medications being taken prior to starting loxapine. ## Food Interactions Alcohol should not be consumed while taking loxapine. Grapefruit or grapefruit juice should also be avoided as it can increase the risk of side effects. ## Pregnancy Use Loxitane is classified as a pregnancy category C medication, which means that there is not enough data to determine that it is safe for use by pregnant women. Therefore, it should be avoided during pregnancy. ## Lactation Use Loxitane is passed into breast milk and it is not thought to be safe for infants. Therefore, nursing mothers should avoid taking loxapine. ## Acute Overdose Symptoms of loxapine overdose include drowsiness, agitation, confusion, and seizures. It is important to seek emergency medical attention if an overdose is suspected. ## Contraindications Loxitane should not be used in patients with known hypersensitivity reaction to it. It should also be avoided in patients with decreased blood pressure, glaucoma, arteriosclerotic heart disease, renal or hepatic impairment, and diabetes mellitus. ## Use Directions Loxitane should be taken exactly as prescribed by your healthcare provider. Do not change doses or stop taking loxapine without consulting your doctor. ## Storage Conditions Loxitane tablets should be stored in a cool, dry place away from light and moisture. The oral solution should be stored in the refrigerator. ## Volume of Distribution Loxitane has a volume of distribution of 26.7-27.3 L/kg. ## Half Life The elimination half-life of loxapine is approximately 9-13 hours. ## Clearance Loxitane has a total body clearance of approximately 2.4-2.7 L/h/kg.Here you find in details version of Loxitane
Some Frequently Asked Questions About Loxitane
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