Mag-Ox
Mag-Ox Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Mag-Ox is a brand name. Its generic name is Magnesium oxide.
Magnesium Oxide
Mag-Ox, also known as magnesia, is an inorganic compound used in a variety of applications. It is used medicinally as a laxative, antacid, and as an ingredient in dietary supplements, and as a mineral supplement in animal feed. It also has industrial uses as a component of insulating materials, and as a raw material in cements, paints, and refractories.
Uses For
Mag-Ox has a variety of uses, including:
- As a laxative to treat constipation
- As an antacid to relieve indigestion, acid reflux and heartburn
- As an ingredient in dietary supplements for its magnesium content
- As a mineral supplement in animal feed
- As a component of insulating materials
- As a raw material in cements, paints, and refractories
Mechanism of Action
Mag-Ox acts as a laxative by creating osmotic pressure in the intestinal lumen. This draws water into the intestine, causing bowel movements. As an antacid, magnesium oxide neutralizes stomach acid by binding to hydrogen ions, thus raising the pH of the stomach contents.
How Long Does it Take to Work
The amount of time it takes for magnesium oxide to work depends on how it is being used. As a laxative, it usually begins working within 6-8 hours. As an antacid, it works quickly to neutralize stomach acid, usually within minutes.
Absorption
Mag-Ox is not very water-soluble and has low intestinal absorption, meaning only a small amount of magnesium is actually absorbed into the bloodstream. The amount of magnesium absorbed depends on the dosage and the form of magnesium oxide used.
Route of Elimination
Magnesium is eliminated from the body primarily through the kidneys. When magnesium oxide is taken orally, most of it is eliminated unchanged in the feces. An insignificant amount is excreted in the urine.
Dosage
The recommended dose of magnesium oxide depends on the individual and the condition being treated. As a laxative, the dose is usually 3-4 grams daily. As an antacid, the dose is usually 250-500 milligrams. For dietary supplementation, the dose is usually 250-500 milligrams daily.
Administration
Mag-Ox can be taken orally with or without food. It should be taken with a full glass of water.
Side Effect
Side effects of magnesium oxide include bloating, nausea, diarrhea, stomach pain, and an unusual taste in the mouth.
Toxicity
Mag-Ox is generally safe and well-tolerated when taken at recommended doses. Overdose of magnesium oxide can cause serious toxicity, leading to muscle weakness, confusion, decreased respiration, low blood pressure, and cardiac arrest.
Precaution
It is important to talk to a doctor or pharmacist before taking magnesium oxide. People with kidney disease, heart disease, or other medical conditions should not take magnesium oxide without consulting a doctor first. Women who are pregnant, breastfeeding, or trying to conceive should not take magnesium oxide without consulting a doctor first.
Interaction
Mag-Ox could interact with certain medications, such as antibiotics, diuretics, and heart medications. Therefore, it is important to tell your doctor or pharmacist about all of the medications you are taking before taking magnesium oxide.
Disease Interaction
Mag-Ox could interact with certain diseases, such as kidney or heart diseases, so it is important to talk with your doctor before taking magnesium oxide. People with kidney disease or heart disease should not take magnesium oxide without consulting a doctor first.
Drug Interaction
Mag-Ox could interact with certain medications, such as antibiotics, diuretics, and heart medications. Therefore, it is important to tell your doctor or pharmacist about all of the medications you are taking before taking magnesium oxide.
Food Interactions
Mag-Ox does not interact with food, however, it is important to take it with a full glass of water to help it be absorbed into the body.
Pregnancy Use
Mag-Ox is classified as a pregnancy category C drug, which means that it may not be safe for use during pregnancy. Women who are pregnant, breastfeeding, or trying to conceive should not take magnesium oxide without consulting a doctor first.
Lactation Use
Mag-Ox is classified as a pregnancy category C drug, which means that it may not be safe for use while breastfeeding. Women who are pregnant, breastfeeding, or trying to conceive should not take magnesium oxide without consulting a doctor first.
Acute Overdose
Overdose of magnesium oxide can cause serious toxicity, leading to muscle weakness, confusion, decreased respiration, low blood pressure, and cardiac arrest. If you think you or someone else has overdosed on magnesium oxide, seek medical attention immediately.
Contraindication
People with known hypersensitivity to magnesium oxide should not take it. People with kidney disease or heart disease should not take magnesium oxide without consulting a doctor first. Women who are pregnant, breastfeeding, or trying to conceive should not take magnesium oxide without consulting a doctor first.
Use Direction
The recommended dose of magnesium oxide depends on the individual and the condition being treated. For dietary supplementation, the dosage is usually 250-500 milligrams daily. As a laxative, the dose is usually 3-4 grams daily. As an antacid, the dose is usually 250-500 milligrams. Mag-Ox should be taken with a full glass of water.
Storage Condition
Mag-Ox should be stored at room temperature, away from heat and moisture.
Volume of Distribution
The volume of distribution of magnesium oxide is not known.
Half Life
The half-life of magnesium oxide is not known.
Clearance
The clearance of magnesium oxide is not known.
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