Levofloxacinum
Levofloxacinum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Levofloxacinum is a brand name. Its generic name is Levofloxacin.
Levofloxacinum Introduction
Levofloxacinum is an antibiotic that belongs to the family of medications known as quinolones. It is used to treat a variety of bacterial infections including, chest and urinary tract infections. It works by stopping the growth of bacteria.
Uses for Levofloxacinum
Levofloxacinum is used to treat a variety of bacterial infections, including:
- respiratory tract infections
- urinary tract infections, including prostatitis
- skin and soft tissue infections
- acute bacterial sinusitis
- complicated intra-abdominal infections
- chronic bacterial prostatitis
Mechanism of Action
Levofloxacinum works by interfering with bacterial DNA synthesis. It inhibits the action of an enzyme called DNA gyrase, so that the bacteria can no longer reproduce. This stops the bacteria from growing and allows the body’s natural defences to fight the infection.
How Long Does it Take to Work?
Levofloxacinum typically starts to work within 48-72 hours, although this can vary depending on the severity and type of infection.
Absorption
Levofloxacinum is rapidly and almost completely absorbed from the gastrointestinal tract.
Route of Elimination
Levofloxacinum is eliminated largely in the urine, with smaller amounts eliminated in the feces. It is eliminated primarily by the kidneys.
Dosage
The dosage of Levofloxacinum will vary depending on the type and severity of the infection being treated. The usual dose for adults is 250-500mg per day, taken once or twice daily. For children, the dose may be lower depending on the child's weight and age.
Administration
Levofloxacinum should be taken with plenty of fluids. It should not be taken with alcohol, as this may increase the risk of side effects. It should be taken on an empty stomach, at least one hour before food, or two hours after food.
Side Effects
The most common side effects associated with Levofloxacinum include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, fatigue, and rash. More serious side effects may include allergic reactions, tendon or joint pain, muscle weakness, seizures, and liver damage.
Toxicity
At therapeutic doses, Levofloxacinum is generally well-tolerated. The most serious adverse reaction is liver injury, which can occur at high doses. Other less serious but more commonly reported adverse reactions include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, fatigue, and rash.
Precautions
Before using Levofloxacinum, talk to your healthcare provider about any allergies, your medical history, and any other medications you may be taking. Tell your healthcare provider if you have ever had any kidney or liver problems, G6PD deficiency, any joint or tendon problems, or any mental health issues including depression or suicidal thoughts. Let your healthcare provider know if you are pregnant or breastfeeding before using Levofloxacinum.
Interactions
Levofloxacinum can interact with other medications, vitamins, and herbal supplements. Tell your healthcare provider about all other medications you are taking before taking Levofloxacinum. Some medications that may interact with Levofloxacinum include blood thinners, anti-seizure medications, and certain antibiotics.
Disease Interactions
Levofloxacinum should not be used by patients with a known hypersensitivity to quinolone antibiotics. Patients with a history of tendon disorders should also not use Levofloxacinum. Patients with any kidney or liver disease should use this medication with caution.
Drug Interactions
Levofloxacinum can interact with other medications, vitamins, and herbal supplements. Tell your healthcare provider about all other medications you are taking before taking Levofloxacinum. Some medications that may interact with Levofloxacinum include blood thinners, anti-seizure medications, and certain antibiotics.
Food Interactions
Levofloxacinum should be taken on an empty stomach. Avoid taking it with alcohol, as this may increase the risk of side effects.
Pregnancy Use
Levofloxacinum should not be used during pregnancy, as it may cause birth defects. Tell your healthcare provider if you are pregnant before taking Levofloxacinum.
Lactation Use
Levofloxacinum is not recommended for use in breastfeeding women, as it may pass into breast milk and cause harm to a nursing baby. Tell your healthcare provider if you are breastfeeding before taking Levofloxacinum.
Acute Overdose
Symptoms of an acute overdose of Levofloxacinum include confusion, tremors, restlessness, nausea, and vomiting. Seek medical attention immediately if you think you have taken too much Levofloxacinum.
Contraindication
Levofloxacinum should not be used by patients with a known hypersensitivity to quinolones. Patients with a history of tendon disorders should also not use Levofloxacinum. Patients with any kidney or liver disease should use this medication with caution.
Use Direction
Levofloxacinum should be taken exactly as prescribed by your healthcare provider. Do not take more or less of the medication than prescribed. Take the medication on an empty stomach at least one hour before food, or two hours after food. Take Levofloxacinum with plenty of fluids. Do not take with alcohol, as this may increase the risk of side effects. Do not stop taking the medication early, or skip doses, even if you feel better.
Storage Condition
Levofloxacinum should be stored at room temperature, away from heat and direct light. Keep the medication in the original container, and keep it tightly closed. Do not store the medication in the bathroom or near a sink. Keep all medication out of sight and reach of children.
Volume of Distribution
Levofloxacinum is highly soluble in water and is widely distributed throughout the body. It has a volume of distribution of 0.77-1.5 L/kg.
Half Life
The half-life of Levofloxacinum is about 8 hours, but may be longer in patients with reduced renal function.
Clearance
Renal clearance of Levofloxacinum is approximately 25 mL/min. Liver metabolism is not significant.
Here you find in details version of Levofloxacinum
Some Frequently Asked Questions About Levofloxacinum
s.What is Levofloxacinum?
Levofloxacinum is an antibiotic medication used to treat a wide variety of bacterial infections. It belongs to a class of antibiotics called fluoroquinolones and works by stopping the growth of bacteria.
What are the uses of Levofloxacinum?
Levofloxacinum is used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
Is Levofloxacinum an antibiotic?
Yes, Levofloxacinum is an antibiotic medication used to treat bacterial infections.
What is the usual adult dose of Levofloxacinum?
The usual adult dose of Levofloxacinum is 250 to 750 mg daily, depending on the type of infection being treated.
Is Levofloxacinum a form of penicillin?
No, Levofloxacinum is not a form of penicillin; it belongs to a class of antibiotics called fluoroquinolones.
What is Levofloxacinum used for?
Levofloxacinum is used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
Should I take Levofloxacinum with food?
Levofloxacinum can be taken with or without food. However, for best absorption, it should be taken with a full glass of water.
How long do I need to take Levofloxacinum?
It is important to take Levofloxacinum until you have completed the prescribed course of treatment, even if you start to feel better. Generally, Levofloxacinum is taken for a period of 5 to 14 days.
Why is Levofloxacinum prescribed?
Levofloxacinum is prescribed for a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, urinary tract infections, and some sexually transmitted diseases.
When should I take Levofloxacinum?
Levofloxacinum should be taken at least 1 hour before or 2 hours after meals, or as directed by your doctor.
Can I drink alcohol while taking Levofloxacinum?
No, it is not recommended to drink alcohol while taking Levofloxacinum as it may increase the risk of side effects. It is best to check with your doctor first before drinking alcohol.
Are there any side effects associated with Levofloxacinum?
Common side effects associated with Levofloxacinum include nausea, diarrhea, dizziness, headache, and rashes. More serious side effects include liver damage, tendon rupture, and changes in heart rhythm.
Do I need to avoid sunlight while taking Levofloxacinum?
Yes, it is important to avoid direct sunlight and sunlamps while taking Levofloxacinum, as it can increase the risk of sunburn. If you must go out in the sun, wear protective clothing and use sunblock.
What should I do if I miss a dose of Levofloxacinum?
If you miss a dose of Levofloxacinum, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
How long does it take for Levofloxacinum to work?
Levofloxacinum begins to work quickly, usually within the first 24 hours of taking it. However, it is important to take the full course of medication as prescribed in order to fully eliminate the infection.
Is Levofloxacinum suitable for children?
Only in very specific cases. It is important to discuss the risks and benefits with your doctor to determine if Levofloxacinum is suitable for children.
Will Levofloxacinum treat a virus?
No, Levofloxacinum is an antibiotic medication that is used to treat bacterial infections only. It will not be effective in treating viral infections.
Does Levofloxacinum interact with any other medications?
Yes, Levofloxacinum may interact with other medications, including certain antibiotics, antifungals, drugs used to treat high cholesterol levels, and drugs used to treat tuberculosis. It is important to discuss all medications you are taking with your doctor before taking Levofloxacinum.
Does Levofloxacinum cause weight gain?
No, Levofloxacinum does not typically cause weight gain. Weight gain is more commonly associated with some of the other antibiotics, such as macrolides.
Can Levofloxacinum be used to treat UTI?
Yes, Levofloxacinum can be used to treat urinary tract infections (UTI). It is important to complete the full course of treatment for it to be effective.
What are the storage instructions for Levofloxacinum?
Levofloxacinum should be stored at room temperature, between 15-30°C (59-86°F), and away from light and moisture. It should also be kept out of the reach of children.
What are the possible allergic reactions to Levofloxacinum?
Allergic reactions to Levofloxacinum may include rashes, hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, stop taking Levofloxacinum and seek medical attention immediately.
Can I take ibuprofen with Levofloxacinum?
Yes, ibuprofen can be taken with Levofloxacinum. It is important to follow the instructions of your doctor or pharmacist to avoid any interactions.
Should I take Levofloxacinum with food?
Levofloxacinum can be taken with or without food. However, for best absorption, it should be taken with a full glass of water.
Is Levofloxacinum safe for pregnant women?
Levofloxacinum is generally not recommended for use in pregnant women, as it can increase the risk of adverse effects on the developing baby. It is important to discuss the risks and benefits with your doctor before taking this medication.
Are there any interactions between Levofloxacinum and other medications?
Yes, Levofloxacinum can interact with other medications, including certain antibiotics, antifungal medications, and drugs used to treat high cholesterol levels. It is important to discuss all medications you are taking with your doctor before taking Levofloxacinum.
Can Levofloxacinum treat a bacterial infection?
Yes, Levofloxacinum is an antibiotic medication used to treat a number of bacterial infections, including bronchitis, pneumonia, sinus infections, skin infections, and urinary tract infections.
How quickly will I start to feel better after taking Levofloxacinum?
Most people start to feel better within 24 hours of taking Levofloxacinum, however it is important to complete the full course of treatment for it to be effective.
Can I take Levofloxacinum with dairy products?
No, it is best to avoid taking Levofloxacinum with dairy products, such as milk, cheese, and yogurt, as they can decrease the effectiveness of Levofloxacinum.
How long can I take Levofloxacinum?
It is important to take Levofloxacinum until you have completed the prescribed course of treatment, even if you start to feel better. Generally, Levofloxacinum is taken for a period of 5 to 14 days.
Should I take Levofloxacinum at the same time every day?
Yes, it is best to take Levofloxacinum at the same time each day to maintain an even level of medication in your blood.
Does Levofloxacinum have any interactions with alcohol?
Yes, it is not recommended to drink alcohol while taking Levofloxacinum as it may increase the risk of side effects. It is best to check with your doctor first before drinking alcohol.
Can I take Levofloxacinum while breastfeeding?
No, Levofloxacinum is not recommended for use in breastfeeding women because it can pass into breast milk and may harm a nursing infant. It is important to discuss the risks and benefits with your doctor.
Can Levofloxacinum cause stomach upset?
Yes, Levofloxacinum can cause abdominal cramps, nausea, vomiting, and diarrhea. It is important to drink plenty of fluids to stay hydrated and talk to your doctor if the side effects persist.
Does Levofloxacinum ever need to be refrigerated?
No, Levofloxacinum does not need to be refrigerated. It should be stored at room temperature, between 15-30°C (59-86°F), and away from light and moisture.
Can Levofloxacinum affect the liver?
Yes, Levofloxacinum can cause liver damage in some people. It is important to report any changes in liver function to your doctor immediately.
Can I breastfeed while taking Levofloxacinum?
No, Levofloxacinum is not recommended for use in breastfeeding women because it can pass into breast milk and may harm a nursing infant. It is important to discuss the risks and benefits with your doctor.
Can I take vitamins while taking Levofloxacinum?
Yes, you can take vitamins while taking Levofloxacinum. However, it is best to check with your doctor first, as some vitamins may interact with Levofloxacinum.
Can I take Levofloxacinum with other medications?
Yes, Levofloxacinum may be taken with other medications, however it is important to discuss all medications you are taking with your doctor to avoid any interactions.
Can Levofloxacinum cause kidney damage?
Yes, Levofloxacinum can cause kidney damage in some people. It is important to stay well hydrated while taking Levofloxacinum and to report any changes in urine output to your doctor immediately.
Can Levofloxacinum cause yeast infections?
Yes, taking Levofloxacinum can upset the natural balance of bacteria in the body, which may lead to yeast infections. It is important to talk to your doctor if you experience any signs or symptoms of a yeast infection.
Does Levofloxacinum cause drowsiness?
Yes, Levofloxacinum can cause drowsiness and dizziness. It is important to avoid driving or operating machinery until you know how Levofloxacinum will affect you.
Does Levofloxacinum cause hair loss?
No, Levofloxacinum is not known to cause hair loss. However, if you are taking other medications, it is important to talk to your doctor to see if they can cause hair loss.
Can Levofloxacinum be used to treat skin infections?
Yes, Levofloxacinum is an effective treatment for many types of skin infections, including bacterial skin