Dexibuprofen

Dexibuprofen Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dexibuprofen is a brand name. Its generic name is Dexibuprofen.

Introduction

Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID), which is used for relief of pain and inflammation. It belongs to the class of drugs called COX-2 inhibitors, which reduces pain and inflammation. Dexibuprofen was approved by the US FDA in July 2017.

Uses

Dexibuprofen is used to treat moderate to severe pain, inflammation and stiffness associated with arthritis and musculoskeletal conditions such as bursitis, tendinitis, and joint pain. It is also used to treat headaches, menstrual cramps, and other common pains.

Mechanism of Action

Dexibuprofen works by blocking the action of cyclooxygenase (COX), an enzyme involved in the production of substances called prostaglandins. Prostaglandins are responsible for causing inflammation, pain, and swelling. By blocking the enzyme, Dexibuprofen blocks the production of these prostaglandins, thereby reducing the pain and inflammation caused by the affected condition.

How long does it take to work?

The effects of Dexibuprofen typically begin to take effect within 30 minutes to an hour after taking the drug. The drug may take up to 8 hours to show its full effects of relieving pain and inflammation.

Absorption

Dexibuprofen is rapidly and almost completely absorbed from the gastrointestinal tract. The peak serum levels of the drug occur approximately 1-2 hours after oral administration.

Route of Elimination

Dexibuprofen is metabolized in the liver and excreted in the urine and feces.

Dosage

The typical recommended dosage of Dexibuprofen is 400 to 800 mg per day, taken orally in divided doses (usually, twice a day). The dose may be increased or decreased based on the patient’s response to the medication.

Administration

Dexibuprofen is available in oral tablets and capsules, as well as in a liquid suspension. The tablets and capsules should be taken with a glass of water once or twice a day, as directed by the doctor. The liquid form of Dexibuprofen should be taken with food or after meals.

Side Effect

Some of the common side effects of Dexibuprofen include nausea, vomiting, abdominal pain, indigestion, headache, dizziness, and diarrhea. Serious side effects such as bloody or black, tarry stools, chest pain, difficulty breathing, and weakness in the arms and legs have also been reported.

Toxicity

High doses of Dexibuprofen can lead to severe liver or kidney damage and even cause death. Regular monitoring of liver function tests is recommended in patients taking Dexibuprofen. If any signs of liver or kidney damage appear, the dose of Dexibuprofen should be reduced or stopped immediately.

Precautions

Dexibuprofen should be used with caution in patients with a history of asthma, stomach or intestinal ulcers, kidney or liver disease, bleeding disorders, or any other medical condition. It should not be used by pregnant women or those who are breastfeeding. People taking blood thinning medications should also avoid taking Dexibuprofen.

Interactions

Dexibuprofen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexibuprofen.

Disease Interaction

Dexibuprofen may interact with certain diseases, such as asthma, gastrointestinal ulcers, kidney or liver disease, or any other medical condition. People with these diseases should use Dexibuprofen with caution and monitor their condition closely.

Drug Interactions

Dexibuprofen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexibuprofen.

Food Interactions

Dexibuprofen may interact with certain foods, such as dairy products, alcohol, and spicy foods. It is best to avoid these foods while taking Dexibuprofen to minimize any potential interactions.

Pregnancy Use

Dexibuprofen should be used with caution during pregnancy and should only be used if the potential benefits outweigh the risks to the baby. It is not recommended for pregnant women due to the potential for fetal damage or harm.

Lactation Use

Dexibuprofen should not be used while breastfeeding as it can pass into breast milk.

Acute Overdose

An overdose of Dexibuprofen can cause serious side effects, such as nausea, vomiting, abdominal pain, drowsiness, confusion, dizziness, fainting, respiratory depression, and death. If an overdose is suspected, seek medical attention immediately.

Contraindication

Dexibuprofen should not be used in patients with a known hypersensitivity to ibuprofen or other NSAIDs. Patients with a history of asthma, stomach or intestinal ulcers, bleeding disorders, kidney or liver disease, or any other medical condition should also avoid using Dexibuprofen.

Use Directions

Dexibuprofen should be taken exactly as prescribed by the doctor. The tablets and capsules should be taken with a full glass of water once or twice a day, as directed. The liquid form of Dexibuprofen should be taken with food or after meals.

Storage Condition

Dexibuprofen should be stored at room temperature away from direct light and moisture. Keep it away from pets, children, and any other medicines.

Volume of Distribution

Dexibuprofen has a volume of distribution of approximately 0.5 l/kg.

Half Life

The half-life of Dexibuprofen is approximately 2-3 hours.

Clearance

The clearance rate of Dexibuprofen is approximately 0.7 ml/min/kg.

Here you find in details version of Dexibuprofen

Some Frequently Asked Questions About Dexibuprofen

What is Dexibuprofen?

Dexibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce symptoms of inflammation and pain.

What are the uses of Dexibuprofen?

Dexibuprofen is used to treat pain, inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis.

How should I take Dexibuprofen?

Dexibuprofen should be taken exactly as prescribed by your doctor. The usual adult dose is 200 to 400 mg every 4 to 6 hours.

Is Dexibuprofen safe?

Yes, Dexibuprofen is generally safe when taken as prescribed. However, like any medicine, there may be side effects or interactions with other medications.

Is Dexibuprofen habit-forming?

No, Dexibuprofen is not habit-forming and does not have any known abuse potential.

Are there any food or drink interactions with Dexibuprofen?

Yes, Dexibuprofen may interact with alcohol, caffeine, and certain foods. Therefore, it is important to check with your doctor or pharmacist before taking Dexibuprofen.

What are the possible side effects of Dexibuprofen?

Common side effects of Dexibuprofen include abdominal pain, diarrhea, nausea, and headache. More serious side effects can occur, so it is important to talk to your doctor if you experience any unusual symptoms while taking Dexibuprofen.

Does Dexibuprofen have any interactions with other medications?

Yes, Dexibuprofen may interact with some other medications, including aspirin, warfarin, and other NSAIDs. It is important to consult your doctor or pharmacist before taking any medications in combination with Dexibuprofen.

What is the maximum daily dose of Dexibuprofen?

The maximum daily dose of Dexibuprofen is 800 mg per day for adults. For children, the maximum daily dose is determined based on age and weight.

What is the difference between Dexibuprofen and ibuprofen?

Dexibuprofen is a newer, long-acting version of ibuprofen, with a longer duration of action in the body. Dexibuprofen is usually taken less frequently than ibuprofen, and is only available as a prescription medication.

Can pregnant or breastfeeding women take Dexibuprofen?

It is not recommended for pregnant or breastfeeding women to take Dexibuprofen. Women who are pregnant or breastfeeding should consult their doctor before taking any medication, including Dexibuprofen.

Is Dexibuprofen the same as aspirin or acetaminophen?

No, Dexibuprofen is not the same as aspirin or acetaminophen. Dexibuprofen is an NSAID, while aspirin and acetaminophen are not NSAIDs.

How does Dexibuprofen work?

Dexibuprofen works by blocking the production of certain chemicals in the body that cause inflammation and pain. This provides relief from the pain and inflammation associated with arthritis.

Can I take Dexibuprofen with other medications?

It is not recommended to take Dexibuprofen with certain other medications, such as aspirin, warfarin, or other NSAIDs. Consult your doctor or pharmacist before taking Dexibuprofen with any other medication.

How long does it take for Dexibuprofen to work?

It can take up to an hour for Dexibuprofen to start relieving pain and inflammation. The effects of Dexibuprofen can last for up to six hours.

In what form is Dexibuprofen available?

Dexibuprofen is available as a tablet, capsule, suspension, and injection. It is also available as an oral liquid for children.

How long does Dexibuprofen take to leave the body?

The half-life of Dexibuprofen is about 8 hours, so it takes an average of 24 to 36 hours for the drug to be completely eliminated from the body.

Can I buy Dexibuprofen over-the-counter?

No, Dexibuprofen is not available over the counter. It is only available by prescription from a doctor.

Is Dexibuprofen addictive?

No, Dexibuprofen is not an addictive drug and has no known abuse potential.

What happens if I take too much Dexibuprofen?

Taking too much Dexibuprofen can cause serious side effects like nausea, vomiting, stomach pain, drowsiness, headache, dizziness, or blurred vision. In some cases, it can even cause stomach or intestinal bleeding. If you take too much Dexibuprofen, you should seek immediate medical attention.

Can I take Dexibuprofen if I have liver or kidney problems?

It is not recommended for people with liver or kidney problems to take Dexibuprofen. People with liver or kidney problems should consult their doctor before taking any medication.

Can Dexibuprofen cause drowsiness?

Yes, Dexibuprofen can cause drowsiness or dizziness in some people. It is important to check with your doctor before taking Dexibuprofen if you are taking other medications that can cause drowsiness.

Does Dexibuprofen interact with other substances?

Yes, Dexibuprofen can interact with certain substances, such as alcohol, caffeine, and certain foods. It is important to discuss all medications and substances with your doctor before taking Dexibuprofen.

How long can I take Dexibuprofen safely?

It is not recommended to take Dexibuprofen for longer than 10 days without consulting a doctor. Taking Dexibuprofen for an extended period of time can increase the risk of serious side effects.

What should I do if I miss a dose of Dexibuprofen?

If you miss a dose of Dexibuprofen, take it as soon as you remember. Do not take two doses at once. If you take too much Dexibuprofen, seek immediate medical attention.

Is Dexibuprofen covered by insurance?

It depends. Most health insurance plans cover some or all of the cost of Dexibuprofen. Check with your insurance provider for details on your coverage.

Are there any long-term side effects of taking Dexibuprofen?

Long-term use of Dexibuprofen can increase the risk of stomach or intestinal bleeding, heart attack, stroke, and kidney damage. If you are taking Dexibuprofen for a prolonged period of time, it is important to talk to your doctor about the risks.

Does Dexibuprofen affect blood pressure?

Yes, Dexibuprofen can cause an increase in blood pressure. People with high blood pressure should consult their doctor before taking any medication, including Dexibuprofen.

Can children take Dexibuprofen?

Dexibuprofen is approved for use in children as young as 2 years old. The dose and form of Dexibuprofen used in children will be determined by the doctor and should be taken according to the doctor’s instructions.

Is Dexibuprofen a steroid?

No, Dexibuprofen is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).

What will happen if I stop taking Dexibuprofen suddenly?

It is not recommended to stop taking Dexibuprofen suddenly. If you need to stop taking Dexibuprofen, talk to your doctor about how to do so safely.

Can I take Dexibuprofen with food?

Yes, Dexibuprofen can be taken with or without food. However, it is important to follow your doctor’s instructions and not take more than the recommended dose.

What other medications can I take with Dexibuprofen?

It is important to talk to your doctor or pharmacist before taking any medications in combination with Dexibuprofen, as some medications can interact with it. Some medications that are safe to take with Dexibuprofen include acetaminophen, ibuprofen, and topical creams.

Can Dexibuprofen be used for headaches?

Yes, Dexibuprofen can be used for the temporary relief of headaches. If you experience frequent or severe headaches, it is important to talk to your doctor.

Does Dexibuprofen help with swelling?

Yes, Dexibuprofen is commonly used to reduce pain and swelling associated with conditions like osteoarthritis and rheumatoid arthritis.

Can I take Dexibuprofen if I have a history of stomach ulcers?

It is not recommended for people with a history of stomach ulcers to take Dexibuprofen. People with a history of stomach ulcers should talk to their doctor before taking any medication.

Can Dexibuprofen help with menstrual cramps?

Yes, Dexibuprofen can help to relieve pain associated with menstrual cramps. If menstrual cramps are severe or frequent, it is important to talk to a doctor.

Is Dexibuprofen suitable for people with allergies?

Yes, Dexibuprofen is suitable for people with allergies. People with allergies should check with their doctor before taking any medication, including Dexibuprofen.

Can I take Dexibuprofen with an antacid?

Yes, you can take Dexibuprofen with an antacid. However, it is important to take antacids at least two hours before or after taking Dexibuprofen to ensure maximum effectiveness.