Dexpro

Dexpro Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dexpro is a brand name. Its generic name is Dexibuprofen.

Introduction

Dexpro is a non-steroidal anti-inflammatory drug (NSAID), which is used for relief of pain and inflammation. It belongs to the class of drugs called COX-2 inhibitors, which reduces pain and inflammation. Dexpro was approved by the US FDA in July 2017.

Uses

Dexpro is used to treat moderate to severe pain, inflammation and stiffness associated with arthritis and musculoskeletal conditions such as bursitis, tendinitis, and joint pain. It is also used to treat headaches, menstrual cramps, and other common pains.

Mechanism of Action

Dexpro works by blocking the action of cyclooxygenase (COX), an enzyme involved in the production of substances called prostaglandins. Prostaglandins are responsible for causing inflammation, pain, and swelling. By blocking the enzyme, Dexpro blocks the production of these prostaglandins, thereby reducing the pain and inflammation caused by the affected condition.

How long does it take to work?

The effects of Dexpro typically begin to take effect within 30 minutes to an hour after taking the drug. The drug may take up to 8 hours to show its full effects of relieving pain and inflammation.

Absorption

Dexpro is rapidly and almost completely absorbed from the gastrointestinal tract. The peak serum levels of the drug occur approximately 1-2 hours after oral administration.

Route of Elimination

Dexpro is metabolized in the liver and excreted in the urine and feces.

Dosage

The typical recommended dosage of Dexpro is 400 to 800 mg per day, taken orally in divided doses (usually, twice a day). The dose may be increased or decreased based on the patient’s response to the medication.

Administration

Dexpro is available in oral tablets and capsules, as well as in a liquid suspension. The tablets and capsules should be taken with a glass of water once or twice a day, as directed by the doctor. The liquid form of Dexpro should be taken with food or after meals.

Side Effect

Some of the common side effects of Dexpro include nausea, vomiting, abdominal pain, indigestion, headache, dizziness, and diarrhea. Serious side effects such as bloody or black, tarry stools, chest pain, difficulty breathing, and weakness in the arms and legs have also been reported.

Toxicity

High doses of Dexpro can lead to severe liver or kidney damage and even cause death. Regular monitoring of liver function tests is recommended in patients taking Dexpro. If any signs of liver or kidney damage appear, the dose of Dexpro should be reduced or stopped immediately.

Precautions

Dexpro should be used with caution in patients with a history of asthma, stomach or intestinal ulcers, kidney or liver disease, bleeding disorders, or any other medical condition. It should not be used by pregnant women or those who are breastfeeding. People taking blood thinning medications should also avoid taking Dexpro.

Interactions

Dexpro may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexpro.

Disease Interaction

Dexpro may interact with certain diseases, such as asthma, gastrointestinal ulcers, kidney or liver disease, or any other medical condition. People with these diseases should use Dexpro with caution and monitor their condition closely.

Drug Interactions

Dexpro may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Dexpro.

Food Interactions

Dexpro may interact with certain foods, such as dairy products, alcohol, and spicy foods. It is best to avoid these foods while taking Dexpro to minimize any potential interactions.

Pregnancy Use

Dexpro should be used with caution during pregnancy and should only be used if the potential benefits outweigh the risks to the baby. It is not recommended for pregnant women due to the potential for fetal damage or harm.

Lactation Use

Dexpro should not be used while breastfeeding as it can pass into breast milk.

Acute Overdose

An overdose of Dexpro can cause serious side effects, such as nausea, vomiting, abdominal pain, drowsiness, confusion, dizziness, fainting, respiratory depression, and death. If an overdose is suspected, seek medical attention immediately.

Contraindication

Dexpro should not be used in patients with a known hypersensitivity to ibuprofen or other NSAIDs. Patients with a history of asthma, stomach or intestinal ulcers, bleeding disorders, kidney or liver disease, or any other medical condition should also avoid using Dexpro.

Use Directions

Dexpro should be taken exactly as prescribed by the doctor. The tablets and capsules should be taken with a full glass of water once or twice a day, as directed. The liquid form of Dexpro should be taken with food or after meals.

Storage Condition

Dexpro should be stored at room temperature away from direct light and moisture. Keep it away from pets, children, and any other medicines.

Volume of Distribution

Dexpro has a volume of distribution of approximately 0.5 l/kg.

Half Life

The half-life of Dexpro is approximately 2-3 hours.

Clearance

The clearance rate of Dexpro is approximately 0.7 ml/min/kg.

Here you find in details version of Dexpro

Some Frequently Asked Questions About Dexpro

What is Dexpro?

Dexpro is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce symptoms of inflammation and pain.

What are the uses of Dexpro?

Dexpro is used to treat pain, inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis.

How should I take Dexpro?

Dexpro should be taken exactly as prescribed by your doctor. The usual adult dose is 200 to 400 mg every 4 to 6 hours.

Is Dexpro safe?

Yes, Dexpro is generally safe when taken as prescribed. However, like any medicine, there may be side effects or interactions with other medications.

Is Dexpro habit-forming?

No, Dexpro is not habit-forming and does not have any known abuse potential.

Are there any food or drink interactions with Dexpro?

Yes, Dexpro may interact with alcohol, caffeine, and certain foods. Therefore, it is important to check with your doctor or pharmacist before taking Dexpro.

What are the possible side effects of Dexpro?

Common side effects of Dexpro include abdominal pain, diarrhea, nausea, and headache. More serious side effects can occur, so it is important to talk to your doctor if you experience any unusual symptoms while taking Dexpro.

Does Dexpro have any interactions with other medications?

Yes, Dexpro may interact with some other medications, including aspirin, warfarin, and other NSAIDs. It is important to consult your doctor or pharmacist before taking any medications in combination with Dexpro.

What is the maximum daily dose of Dexpro?

The maximum daily dose of Dexpro is 800 mg per day for adults. For children, the maximum daily dose is determined based on age and weight.

What is the difference between Dexpro and ibuprofen?

Dexpro is a newer, long-acting version of ibuprofen, with a longer duration of action in the body. Dexpro is usually taken less frequently than ibuprofen, and is only available as a prescription medication.

Can pregnant or breastfeeding women take Dexpro?

It is not recommended for pregnant or breastfeeding women to take Dexpro. Women who are pregnant or breastfeeding should consult their doctor before taking any medication, including Dexpro.

Is Dexpro the same as aspirin or acetaminophen?

No, Dexpro is not the same as aspirin or acetaminophen. Dexpro is an NSAID, while aspirin and acetaminophen are not NSAIDs.

How does Dexpro work?

Dexpro works by blocking the production of certain chemicals in the body that cause inflammation and pain. This provides relief from the pain and inflammation associated with arthritis.

Can I take Dexpro with other medications?

It is not recommended to take Dexpro with certain other medications, such as aspirin, warfarin, or other NSAIDs. Consult your doctor or pharmacist before taking Dexpro with any other medication.

How long does it take for Dexpro to work?

It can take up to an hour for Dexpro to start relieving pain and inflammation. The effects of Dexpro can last for up to six hours.

In what form is Dexpro available?

Dexpro is available as a tablet, capsule, suspension, and injection. It is also available as an oral liquid for children.

How long does Dexpro take to leave the body?

The half-life of Dexpro is about 8 hours, so it takes an average of 24 to 36 hours for the drug to be completely eliminated from the body.

Can I buy Dexpro over-the-counter?

No, Dexpro is not available over the counter. It is only available by prescription from a doctor.

Is Dexpro addictive?

No, Dexpro is not an addictive drug and has no known abuse potential.

What happens if I take too much Dexpro?

Taking too much Dexpro can cause serious side effects like nausea, vomiting, stomach pain, drowsiness, headache, dizziness, or blurred vision. In some cases, it can even cause stomach or intestinal bleeding. If you take too much Dexpro, you should seek immediate medical attention.

Can I take Dexpro if I have liver or kidney problems?

It is not recommended for people with liver or kidney problems to take Dexpro. People with liver or kidney problems should consult their doctor before taking any medication.

Can Dexpro cause drowsiness?

Yes, Dexpro can cause drowsiness or dizziness in some people. It is important to check with your doctor before taking Dexpro if you are taking other medications that can cause drowsiness.

Does Dexpro interact with other substances?

Yes, Dexpro can interact with certain substances, such as alcohol, caffeine, and certain foods. It is important to discuss all medications and substances with your doctor before taking Dexpro.

How long can I take Dexpro safely?

It is not recommended to take Dexpro for longer than 10 days without consulting a doctor. Taking Dexpro for an extended period of time can increase the risk of serious side effects.

What should I do if I miss a dose of Dexpro?

If you miss a dose of Dexpro, take it as soon as you remember. Do not take two doses at once. If you take too much Dexpro, seek immediate medical attention.

Is Dexpro covered by insurance?

It depends. Most health insurance plans cover some or all of the cost of Dexpro. Check with your insurance provider for details on your coverage.

Are there any long-term side effects of taking Dexpro?

Long-term use of Dexpro can increase the risk of stomach or intestinal bleeding, heart attack, stroke, and kidney damage. If you are taking Dexpro for a prolonged period of time, it is important to talk to your doctor about the risks.

Does Dexpro affect blood pressure?

Yes, Dexpro can cause an increase in blood pressure. People with high blood pressure should consult their doctor before taking any medication, including Dexpro.

Can children take Dexpro?

Dexpro is approved for use in children as young as 2 years old. The dose and form of Dexpro used in children will be determined by the doctor and should be taken according to the doctor’s instructions.

Is Dexpro a steroid?

No, Dexpro is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).

What will happen if I stop taking Dexpro suddenly?

It is not recommended to stop taking Dexpro suddenly. If you need to stop taking Dexpro, talk to your doctor about how to do so safely.

Can I take Dexpro with food?

Yes, Dexpro can be taken with or without food. However, it is important to follow your doctor’s instructions and not take more than the recommended dose.

What other medications can I take with Dexpro?

It is important to talk to your doctor or pharmacist before taking any medications in combination with Dexpro, as some medications can interact with it. Some medications that are safe to take with Dexpro include acetaminophen, ibuprofen, and topical creams.

Can Dexpro be used for headaches?

Yes, Dexpro can be used for the temporary relief of headaches. If you experience frequent or severe headaches, it is important to talk to your doctor.

Does Dexpro help with swelling?

Yes, Dexpro is commonly used to reduce pain and swelling associated with conditions like osteoarthritis and rheumatoid arthritis.

Can I take Dexpro if I have a history of stomach ulcers?

It is not recommended for people with a history of stomach ulcers to take Dexpro. People with a history of stomach ulcers should talk to their doctor before taking any medication.

Can Dexpro help with menstrual cramps?

Yes, Dexpro can help to relieve pain associated with menstrual cramps. If menstrual cramps are severe or frequent, it is important to talk to a doctor.

Is Dexpro suitable for people with allergies?

Yes, Dexpro is suitable for people with allergies. People with allergies should check with their doctor before taking any medication, including Dexpro.

Can I take Dexpro with an antacid?

Yes, you can take Dexpro with an antacid. However, it is important to take antacids at least two hours before or after taking Dexpro to ensure maximum effectiveness.