Deflarux
Deflarux Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Deflarux is a brand name. Its generic name is Deflazacort.
Introduction
Deflarux is a synthetic glucocorticoid used to treat a variety of inflammatory and autoimmune conditions, such as rheumatoid arthritis, inflammatory bowel conditions, and asthma. It decreases inflammation and suppresses the immune system.Uses
Deflarux can be used to control inflammation and discomfort caused by a variety of diseases and conditions, including rheumatoid arthritis, lupus, asthma, inflammatory bowel disease, polymyalgia rheumatica, and other autoimmune conditions.Mechanism of Action
Deflarux acts by reducing levels of inflammation-causing chemicals in the body and by suppressing the immune system. It binds to certain glucocorticoid receptors in the cell nucleus that reduce inflammation.How Long Does it Take to Work?
The effects of deflazacort may begin to be noticed within 1-2 weeks of beginning treatment, however it may take up to 6 weeks to reach its full anti-inflammatory effect.Absorption
Deflarux can be absorbed through the digestive system when taken orally.Route of Elimination
Deflarux is eliminated via the liver and kidneys in the form of metabolites.Dosage
Deflarux is available in oral tablets (6mg, 18mg, and 30mg) and an injectable form (10mg/mL). The recommended dose for adult for inflammatory and autoimmune conditions is 7.5-30mg per day, divided into 2-3 doses. The recommended dose for pediatric for inflammatory and autoimmune conditions is 0.3-1mg/kg per day, divided into 2-3 doses.Administration
Deflarux should be taken with food to increase its absorption. On days when you skip a dose, take your next dose at your regularly scheduled time.Side Effects
The most common side effects of Deflarux is weight gain, swelling, and acne. Other rare side effects may include stomach pain, headaches, dizziness, and insomnia.Toxicity
Deflarux is generally considered safe when used as instructed. However, long-term use can lead to serious side effects such as thinning of the bones (osteoporosis), high blood glucose levels, an increased risk of infection, and an increased risk of certain types of cancer.Precautions
Patients taking Deflarux should not stop taking it abruptly, as this can worsen symptoms. Patients should also not take more of this medication than prescribed. Common side effects such as acne may occur, however it is important to contact your doctor if more serious side effects develop.Interactions
Deflarux may interact with other medications such as antibiotics, antifungals, and immunosuppressants. It is important to tell your doctor about all medications you are taking.Disease Interactions
Deflarux is not recommended for use in people with diabetes, glaucoma, tuberculosis, or any other active infections.Drug Interactions
Deflarux can interact with other medications, such as antibiotics, antifungals, and immunosuppressants. It is important to tell your doctor about all medications you are taking.Food Interactions
Deflarux should be taken with food to increase its absorption.Pregnancy Use
Deflarux is categorized as pregnancy category C by the FDA. This means that the use of deflazacort during pregnancy is not recommended unless the potential benefit to the mother outweighs any potential risks to the fetus.Lactation Use
It is not known whether Deflarux passes into breastmilk. Therefore, breastfeeding is not recommended while taking this medication. Women should discuss any potential risks to their infant with their physician.Acute Overdose
If an overdose is suspected, seek medical attention immediately. Symptoms may include weight gain, swelling, headaches, dizziness, and insomnia.Contraindication
Deflarux should not be used in people with known hypersensitivity to the drug or any of its components.Use Direction
Take the dosage as recommended by your doctor. Do not take a larger dose or take it more often than prescribed. Do not stop taking it abruptly as this can worsen your condition.Storage Condition
Store deflazacort tablets and injectable at room temperature.Volume of Distribution
The volume of distribution of deflazacort is 17.3L.Half Life
The half-life of deflazacort is 4-8 hours.Clearance
The clearance of deflazacort is 66ml/min.Here you find in details version of Deflarux
Some Frequently Asked Questions About Deflarux
in the answer use continue reading optionWhat is Deflarux?
Deflarux is a corticosteroid used to treat inflammatory conditions. It works by decreasing inflammation, swelling, and joint pain. It is available as a tablet and oral suspension and is used as a first-line agent for the management of different conditions such as Duchenne muscular dystrophy, rheumatoid arthritis, and systemic lupus erythematosus.
What is the dosage of Deflarux?
The recommended dosage of Deflarux for adults is 6 to 9 mg/day, taken orally in divided doses. The dose may be adjusted depending on response or condition. The dose should be reduced in elderly patients and in those with liver or kidney impairment.
Who should not take Deflarux?
People who are hypersensitive to prednisone, hydrocortisone, or to any of the excipients present in the formulation must not take Deflarux. Patients with active or inactive liver disease should not take Deflarux because it can cause an elevation in the liver enzymes. Pregnant women should also not take Deflarux as it can be harmful to the developing fetus.
What are the common side effects of Deflarux?
Common side effects of Deflarux include nausea, vomiting, stomach upset, headache, dizziness, tiredness, increased appetite, and weight gain. Other more serious side effects of Deflarux include changes in mood, acne, insomnia, and increased risk of infections.
What are the potential interactions with other medications?
Deflarux may interact with certain medications, including anticoagulants (blood thinners), antigout medications, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), immunosuppressive drugs, and oral contraceptives. It is important to tell your doctor about all medications you are currently taking before taking Deflarux.
Is Deflarux available over-the-counter (OTC)?
No, Deflarux is a prescription medication and is not available over-the-counter.
Can Deflarux be used in children?
Deflarux is approved for use in children 3 and older. The recommended dose for children is 0.9 to 2.7 mg/kg/day, taken orally in divided doses. Your child's doctor will determine the dose that is appropriate for your child.
Does Deflarux cause weight gain?
Deflarux may cause weight gain in some people as it increases appetite. If you experience weight gain while taking Deflarux, talk to your doctor who may adjust the dose or recommend a suitable diet plan.
What if I forget to take Deflarux?
If you forget to take a dose of Deflarux, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take more than the recommended dose.
Can I take Deflarux with alcohol?
No, you should avoid drinking alcohol while taking Deflarux as it can increase the risk of side effects.
Are there any laboratory tests that I need to do regularly while taking Deflarux?
Your doctor may request certain laboratory tests, such as complete blood count, blood urea, creatinine, liver function tests, and urine analysis, to monitor your response to therapy and to detect any side effects. Make sure to get tested regularly as instructed by your doctor.
Can I take ibuprofen while taking Deflarux?
It is generally not recommended to take ibuprofen (NSAID) while taking Deflarux as the combination of these medications may increase the risk of side effects. Talk to your doctor before taking any medications while taking Deflarux.
What is the best time of day to take Deflarux?
It is generally recommended to take Deflarux at the same time each day with a glass of water. Talk to your doctor for exact instructions about the best time of day to take Deflarux.
Is Deflarux safe for long-term use?
Deflarux can be taken safely for long-term use if prescribed by your doctor. However, it is important to monitor for any potential side effects and report them to your doctor. It is also important to have regular check-ups, as well as blood and urine tests, while taking Deflarux for long-term use.
What are the long-term effects of Deflarux?
Long-term use of Deflarux may lead to an increased risk of infections, glucose tolerance, thinning of skin, and osteoporosis. It is important to talk to your doctor about any potential long-term effects of Deflarux.
Can I get vaccinated while taking Deflarux?
It is recommended to avoid live vaccines while taking Deflarux as it may affect the response of the vaccine. Talk to your doctor before taking any vaccinations while taking Deflarux.
Should I be monitored for cataracts while taking Deflarux?
Yes, long-term use of Deflarux can lead to an increased risk of cataracts. Talk to your doctor if you have any concerns or if you experience vision changes while taking Deflarux.
Does Deflarux lowerIimmume system?
Yes, Deflarux can suppress the immune system, making it more difficult for the body to fight off infections. Talk to your doctor if you have any concerns or if you experience any signs of infection while taking Deflarux.
Can I donate blood while taking Deflarux?
No, it is not recommended to donate blood while taking Deflarux as it can be harmful for the recipient. Talk to your doctor before donating blood while taking Deflarux.
What is the storage condition of Deflarux?
Deflarux should be stored at room temperature, away from heat and direct light. Keep the medication in a safe, secure place where children and pets cannot access it.
Can I take Deflarux while pregnant?
No, Deflarux is not recommended for pregnant women as it can be harmful for the developing fetus. Talk to your doctor before taking any medications while pregnant.
Does Deflarux affect fertility?
Yes, long-term use of Deflarux can affect fertility in both men and women. Talk to your doctor if you have any concerns about these potential effects.
Can I stop taking Deflarux abruptly?
No, it is important to follow your doctor's instructions when taking Deflarux. The dose should be gradually reduced before stopping the medication completely. Stopping the medication abruptly can lead to withdrawal symptoms. Talk to your doctor before stopping Deflarux.
Can I take other supplements while taking Deflarux?
It is generally not recommended to take other supplements while taking Deflarux as they can interact with the medication and increase the risk of side effects. Talk to your doctor before taking any supplements while taking Deflarux.
What are the alternatives to Deflarux?
Alternatives to Deflarux include prednisolone, methylprednisolone, and budesonide. Talk to your doctor to determine the best medication for your condition.
Can I take Deflarux with acetaminophen?
Yes, Deflarux can be taken with acetaminophen, but make sure not to take more than the recommended dose. Talk to your doctor if you have any concerns or if you experience any side effects.
Does Deflarux affect hair growth?
Yes, long-term use of Deflarux can cause hair loss. Talk to your doctor if you have any concerns about hair loss while taking Deflarux.
Can I take Deflarux with other medications?
Deflarux may interact with certain medications, including anticoagulants (blood thinners), antigout medications, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), immunosuppressive drugs, and oral contraceptives. Talk to your doctor before taking any medications while taking Deflarux.
Can I take Deflarux with antihistamine?
Yes, Deflarux can be taken with antihistamine, but make sure not to take more than the recommended dose. Talk to your doctor if you have any concerns or if you experience any side effects.
Does Deflarux cause increased thirst?
Yes, Deflarux can cause increased thirst and should be taken with plenty of fluids to reduce the risk of dehydration. Talk to your doctor if you have any concerns or if you experience any side effects.
Does Deflarux interfere with sleep?
Deflarux can cause insomnia, making it difficult to sleep. Talk to your doctor if you have any concerns about insomnia while taking Deflarux.
Does Deflarux affect blood pressure?
Yes, long-term use of Deflarux can cause an increase in blood pressure. Talk to your doctor if you have any concerns about changes in blood pressure while taking Deflarux.
Can Deflarux cause headaches?
Yes, Deflarux can cause headaches as a side effect. Talk to your doctor if you have any concerns or if you experience any side effects.
Can I get the flu while taking Deflarux?
Yes, it is possible to get the flu while taking Deflarux, as the medicine can suppress the immune system, making it more difficult for the body to fight off infections. Talk to your doctor if you experience any signs of infection while taking Deflarux.
Can Deflarux cause ankle swelling?
Yes, Deflarux can cause swelling of the ankles as a side effect. Talk to your doctor if you have any concerns or if you experience any side effects.
Is Deflarux addictive?
No, Deflarux is not considered to be addictive. Make sure to take the medication as prescribed by your doctor and do not take more than the recommended dose.
Does Deflarux have an expiry date?
Yes, Deflarux has an expiry date and should be discarded once this date has passed. Talk to your pharmacist for more information on the expiry date of your medication.
Does Deflarux cause nausea?
Yes, Deflarux can cause nausea as a side effect. Talk to your doctor if you have any concerns or if you experience any side effects.
Does Deflarux cause muscle weakness?
Yes, Deflarux can cause muscle weakness as a side effect. Talk to your doctor if you have any concerns or if you experience any side effects.
Does Deflarux affect blood sugar levels?
Yes, long-term use of Deflarux can affect blood sugar levels. Talk to your doctor if you have