Cefaclor

Cefaclor Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefaclor is a brand name. Its generic name is Cefaclor.

Introduction

Cefaclor, also known as Cefaclorum or Cefaclor Extended-Release, is a cephalosporin antibiotic used to treat bacterial infections. It is typically used to treat ear infections, urinary tract infections, sinus infections, and bronchitis. Cefaclor may also be prescribed for other conditions, as determined by a doctor.

Uses

Cefaclor is used for the treatment of mild to moderate bacterial infections caused by susceptible bacteria in the following locations:
  • Respiratory tract, including bronchitis and pneumonia
  • Gastrointestinal tract, including infections of the esophagus, stomach and small intestine, gall bladder and bile ducts
  • Urinary tract, including infections of the bladder and kidney
  • Skin and soft tissue, including wound infections and abscesses

Mechanism of Action

Cefaclor works by inhibiting the synthesis of bacterial cell walls, thus slowing down the growth and multiplication of the bacteria that cause infections. This ultimately leads to the death of the bacteria, clearing the infection and allowing the patient to recover.

How Long Does It Take to Work?

Cefaclor usually starts to work within a few hours of being taken. However, it may take several days for a full course of treatment to clear the infection fully.

Absorption

Cefaclor is an oral medication, and is quickly and completely absorbed through the gastrointestinal tract. Peak concentrations in the bloodstream can be seen in 1 to 4 hours after administration.

Route of Elimination

Cefaclor is eliminated primarily through the kidneys in the form of metabolites, and is excreted in the urine.

Dosage

Cefaclor is available in several different dosages, and the correct dose will depend on various factors such as the patient's age, weight, and the severity of the infection. The typical dosage for adults and adolescents (12 years and older) is 250 to 500 mg taken two to three times a day. For children under 12, the dosage will depend on the child's weight and will be determined by a doctor.

Administration

Cefaclor should be taken with a full glass of water and can be taken with or without food. The tablets and capsules should be swallowed whole and should not be crushed or chewed.

Side Effect

As with any medication, there is a chance of side effects when taking Cefaclor. Common side effects may include nausea, vomiting, flatulence, and diarrhoea. Other less common side effects may include anaphylactic reactions, hepatitis, neuropathy, skin rash, and haemolytic anaemia.

Toxicity

Cefaclor is generally well tolerated and the risk of toxicity is low. However, if too much of the medication is taken, it can be toxic and cause serious side effects. If a patient suspects they have taken an overdose, they should seek immediate medical attention.

Precautions

Cefaclor should not be used in patients with known hypersensitivity to cephalosporins or drugs in the same class, or any of the ingredients in the medication. It should also be used cautiously in patients with renal or hepatic impairment, or in pregnant or breastfeeding women.

Interactions

Cefaclor has the potential to interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs), oral anticoagulants, antifungals, and oral contraceptives. Patients should inform their doctor about any medications or supplements they are taking.

Disease Interaction

Patients with pre-existing conditions, such as asthma, kidney or liver disease, or blood disorders, should inform their doctor before taking Cefaclor. The medication can cause an allergic reaction in some patients.

Drug Interactions

Cefaclor can interact with other medications, and it is important to inform your doctor about any medications or supplements you are taking so that may be taken into account.

Food Interactions

Cefaclor should be taken at least two hours before or after a meal. Taking it with food may increase the absorption and reduce the effectiveness of the medication.

Pregnancy Use

Cefaclor is classified as a Pregnancy Category B drug, which means that it is not known to be harmful to an unborn baby. However, it should only be used if the benefit outweighs the risk.

Lactation Use

It is not known whether Cefaclor is excreted in breast milk, and therefore it is not recommended for use during lactation.

Acute Overdose

If an overdose of Cefaclor is suspected, the patient should seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, and diarrhoea.

Contraindication

Cefaclor should not be used by patients who are allergic to it or other cephalosporin antibiotics. It should also not be used in patients with renal or hepatic impairment.

Use Directions

Cefaclor tablets should be taken as directed by a doctor. It should be taken with a full glass of water and can be taken with or without food. The tablets and capsules should be swallowed whole and should not be crushed or chewed.

Storage Conditions

Cefaclor tablets should be stored at room temperature in a tightly sealed container. It should be kept in a dry place away from direct sunlight and out of reach of children.

Volume of Distribution

Cefaclor is well distributed to some body tissues and fluids, such as pleural and synovial fluids, as well as the gallbladder.

Half-Life

Cefaclor has a half-life of approximately two hours.

Clearance

Cefaclor is eliminated primarily through the kidneys in the form of metabolites, and is excreted in the urine.

Here you find in details version of Cefaclor

Some Frequently Asked Questions About Cefaclor

What is Cefaclor?

Cefaclor is an oral cephalosporin antibiotic used to treat a variety of bacterial infections in the body.

What is Cefaclor used for?

Cefaclor is commonly used to treat infections caused by bacteria, such as: bronchitis, otitis media, sinus infections, pneumonia, urinary tract infections, and skin infections.

Is Cefaclor a broad-spectrum antibiotic?

Yes, Cefaclor is a broad-spectrum antibiotic, meaning it is effective against a wide range of bacterial infections.

What types of bacteria does Cefaclor treat?

Cefaclor is effective against Gram-positive and Gram-negative bacteria, as well as certain anaerobic bacteria.

How quickly does Cefaclor work?

The effects of Cefaclor can be seen within the first few days of starting treatment. However, it is important to complete the entire course of treatment to ensure that the infection is totally eradicated.

Do I need a prescription to get Cefaclor?

Yes, Cefaclor is a prescription medication and must be obtained from a healthcare professional.

How do I take Cefaclor?

Cefaclor should be taken orally with a full glass of water. It is usually taken every 8 or 12 hours, or as directed by your doctor. It is important to take all of the doses in the prescribed course of treatment to ensure that the infection is totally eradicated.

What are the side effects of Cefaclor?

Common side effects of Cefaclor include nausea, vomiting, diarrhea, rash, and itching. If these symptoms persist or worsen, it is important to contact your doctor. You should also contact your doctor immediately if you experience any serious side effects, such as difficulty breathing, severe abdominal pain, or dark urine.

What should I avoid while taking Cefaclor?

It is important to avoid alcohol, grapefruit juice, and other products that may interact with Cefaclor while taking this medication. Also, you should avoid taking antacids within 2 hours of taking Cefaclor, as this may reduce its effectiveness.

Does Cefaclor interact with other medications?

Yes, Cefaclor can interact with other medications, such as antacids, anticonvulsants, certain diuretics, lithium, methotrexate, phenytoin, probenecid, and certain antibiotics. It is important to tell your doctor about all medications that you are currently taking in order to avoid drug interactions.

What if I forget to take a dose of Cefaclor?

If you forget to take a dose of Cefaclor, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take a double dose to make up for the missed dose.

Can Cefaclor cause an allergic reaction?

Yes, Cefaclor can cause an allergic reaction, which may include symptoms such as: difficulty breathing, hives, swollen face, and rash. Seek medical attention immediately if you experience any of these symptoms.

Can I take Cefaclor if I am pregnant or breastfeeding?

It is generally not recommended to take Cefaclor if you are pregnant or breastfeeding. Speak with your doctor to discuss the risks and benefits of taking Cefaclor while pregnant or breastfeeding.

Can I give Cefaclor to my child?

Cefaclor is generally not recommended for children under the age of 12. Speak with your doctor to determine if Cefaclor is safe for your child.

What should I do if I experience an overdose of Cefaclor?

It is important to seek medical attention immediately if you experience an overdose of Cefaclor. Symptoms of an overdose may include nausea, vomiting, and abdominal pain.

Does Cefaclor cause drowsiness?

Yes, Cefaclor can cause drowsiness or dizziness. Avoid operating machinery or driving while taking this medication.

Can I take Cefaclor with food?

Yes, it is safe to take Cefaclor with food. However, it is important to remember not to take antacids within 2 hours of taking Cefaclor.

How should I store Cefaclor?

Cefaclor should be stored at room temperature in a dry, dark place. Keep the medication away from direct light, heat, and moisture.

Is Cefaclor safe for long-term use?

It is generally not recommended to use Cefaclor for long-term use. Speak with your doctor about the risks and benefits of using Cefaclor for long-term treatment.

Does Cefaclor affect birth control?

Yes, Cefaclor can interact with certain birth control medications. Speak with your doctor to determine the best method of birth control to use while taking Cefaclor.

Can I take Cefaclor with dairy products?

It is generally safe to take Cefaclor with dairy products. However, it is important to remember not to take antacids within 2 hours of taking Cefaclor.

Can I take Cefaclor for a viral infection?

No, Cefaclor is only effective against bacterial infections, and will not be effective for treating a viral infection.

Can I take Cefaclor with ibuprofen?

Yes, it is generally safe to take Cefaclor with ibuprofen. However, it is important to discuss any drug interactions with your doctor.

Does Cefaclor cause weight gain?

Weight gain is not a common side effect of Cefaclor. If you experience unexplained weight gain while taking Cefaclor, speak with your doctor.

Can Cefaclor cause kidney damage?

There is a risk of kidney damage with long-term use of Cefaclor, especially at high doses. It is important to discuss any potential risks with your doctor before taking Cefaclor.

Can I take Cefaclor with an ACE inhibitor?

Yes, it is generally safe to take Cefaclor with an ACE inhibitor. However, it is important to discuss any drug interactions with your doctor.

Is Cefaclor safe for elderly patients?

Yes, Cefaclor can be used by elderly patients. However, elderly patients may be more prone to side effects, such as nausea, vomiting, and abdominal pain. Speak with your doctor about the risks and benefits of taking Cefaclor for elderly patients.

What should I do if I experience an allergic reaction to Cefaclor?

If you experience an allergic reaction to Cefaclor, such as difficulty breathing, hives, or rash, seek medical attention immediately. You should also contact your doctor if any of these symptoms persist or worsen.

Can I take Cefaclor with vitamins?

It is generally safe to take Cefaclor with vitamins. However, it is important to discuss any potential drug interactions with your doctor before taking Cefaclor.

Is Cefaclor effective against MRSA?

Yes, Cefaclor is effective against Methicillin-resistant Staphylococcus aureus (MRSA).

Can I take Cefaclor with Tylenol?

Yes, it is generally safe to take Cefaclor with Tylenol. However, it is important to discuss any potential drug interactions with your doctor before taking Cefaclor.

Does Cefaclor treat strep throat?

Yes, Cefaclor is effective against Streptococcus pyogenes, which can cause strep throat.

Can I take Cefaclor while breastfeeding?

It is generally not recommended to take Cefaclor while breastfeeding. Speak with your doctor to discuss the risks and benefits of taking Cefaclor while breastfeeding.

Is Cefaclor effective against staph infections?

Yes, Cefaclor is effective against many types of staph infections, including Methicillin-resistant Staphylococcus aureus (MRSA).

Does Cefaclor cause nausea?

Yes, nausea is a common side effect of Cefaclor. If this symptom persists or worsens, it is important to contact your doctor.

Does Cefaclor treat UTIs?

Yes, Cefaclor is effective against urinary tract infections (UTIs).

Can I take Cefaclor if I am allergic to penicillin?

Yes, it is generally safe for those who are allergic to penicillin to take Cefaclor, as Cefaclor is not a penicillin-based antibiotic.

Can I take Cefaclor with other antibiotics?

It is generally not recommended to take Cefaclor with other antibiotics, as this may increase the risk of drug interactions. Speak with your doctor before taking Cefaclor with other medications.

Can I take Cefaclor if I have asthma?

Yes, Cefaclor can be taken by those with asthma. However, there may be a risk of an allergic reaction. Speak with your doctor to discuss the risks and benefits of taking Cefaclor if you have asthma.

Does Cefaclor treat ear infections?

Yes, Cefaclor is commonly used to treat otitis media (ear infections).

Can I take Cefaclor with probiotics?

Yes, it is generally safe to take Cefaclor with probiotics. However, it is important to discuss any potential drug interactions with your doctor before taking Cefaclor.

Does Cefaclor have any long-term effects?

Long-term use of Cefaclor can cause kidney damage, especially at high doses. Speak with your doctor to discuss the risks and benefits of taking Cefaclor for long-term treatment.