Benzylpénicilline
Benzylpénicilline Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Benzylpénicilline is a brand name. Its generic name is Benzylpenicillin.
Introduction
Benzylpénicilline, also known as penicillin G, is an antibiotic used to treat bacterial infections. It belongs to a group of antibiotics called beta-lactams, and works by interfering with the production of bacterial cell walls.Uses
Benzylpénicilline is used to treat infections caused by susceptible bacteria, including: skin infections, urinary tract infections, throat infections, and infections of the respiratory tract. It is also used to prevent post-surgical wound infections and preterm delivery.Mechanism of Action
Benzylpénicilline works by irreversibly binding to penicillin-binding proteins (PBPs) in bacterial cell walls, preventing the bacteria from forming new cell walls during multiplication. This causes bacteria cells to rupture and die, ultimately leading to the clearing of infection.How Long Does It Take to Work?
It typically takes about 1 to 2 weeks for benzylpenicillin to begin working. However, this time can vary depending on the severity of the infection.Absorption
Benzylpénicilline is not efficiently absorbed from the gastrointestinal tract and must be administered intravenously or intramuscularly.Route of Elimination
Benzylpénicilline is eliminated primarily by the kidneys by glomerular filtration.Dosage
The dosage of benzylpenicillin will depend on the type and severity of the infection. Typical intravenous dosage for adults is 500,000 to 1 million units daily, administered in four to six equal doses over the course of 24 hours. Intramuscular doses should be 600,000 to 1 million units daily for adults, given in two to four equal doses.Administration
Benzylpénicilline can be administered intravenously or intramuscularly. It should be reconstituted according to the manufacturer's instructions prior to administration. It should only be administered by a healthcare professional.Side Effect
Common side effects of benzylpenicillin include nausea, vomiting, and diarrhea. More severe side effects can include anaphylaxis, Stevens-Johnson syndrome, and interstitial nephritis.Toxicity
Benzylpénicilline is associated with a low rate of toxicity. However, severe hypersensitivity reactions and renal toxicity have been reported in rare cases.Precautions
It is important to tell your doctor about any allergies you have and any medications you are taking. Patients with renal impairment, asthma, and suspected or confirmed sensitivity to penicillins should not be given benzylpenicillin.Interaction
Benzylpénicilline can interact with other drugs, including antacids, diuretics, and probenecid, increasing the risk of side effects or reducing the effectiveness of the drug.Disease Interaction
Patients with a history of allergies or asthma should not be given benzylpenicillin, as the risk of a serious allergic reaction is high. Patients with renal impairment should also be cautious when taking the drug, as it may cause renal toxicity.Drug Interaction
Benzylpénicilline can interact with other drugs, including antacids, diuretics, and probenecid, increasing the risk of side effects or reducing the effectiveness of the drug.Food Interactions
There are no known food interactions associated with benzylpenicillin.Pregnancy Use
Benzylpénicilline should only be used during pregnancy if the potential benefit outweighs the potential risk.Lactation Use
It is not known if benzylpenicillin is excreted in breast milk. Therefore, it is best to avoid using the drug while breastfeeding.Acute Overdose
In the event of an acute overdose, benzylpenicillin should be immediately removed from circulation. Symptoms of an overdose include confusion, seizures, and abdominal pain.Contraindication
Patients with a known hypersensitivity to penicillins or cephalosporins should not be given benzylpenicillin.Use Direction
Benzylpénicilline should be used exactly as prescribed by a healthcare provider.Storage Condition
Benzylpénicilline should be stored at 20-25°C (68-77°F) and protected from light.Volume of Distribution
Benzylpénicilline has a volume of distribution of 0.4-1.1 L/kg.Half Life
The half life of benzylpenicillin is approximately 30 minutes.Clearance
The clearance of benzylpenicillin is approximately 0.3-0.8 L/hr/kg.Here you find in details version of Benzylpénicilline
Some Frequently Asked Questions About Benzylpénicilline
Benzylpénicilline Questions and Answers
What is Benzylpénicilline?
Benzylpénicilline, also known as penicillin G, is a form of antibiotic drug belonging to the penicillin family. It is used to treat a wide range of bacterial infections.
How does Benzylpénicilline work?
Benzylpénicilline works by stopping the growth of bacteria. It does this by preventing the bacteria from forming a protective cell wall. This stops them from growing and multiplying.
What infections does Benzylpénicilline treat?
Benzylpénicilline is used to treat a wide range of bacterial infections, such as chest infections, skin infections, blood infections, bone infections, respiratory tract infections, dental abscesses, and meningitis.
Can I buy Benzylpénicilline over the counter?
No, Benzylpénicilline is a prescription-only medication and must be prescribed by a doctor before it can be obtained.
How do I take Benzylpénicilline?
Benzylpénicilline is usually prescribed as an injection and is administered directly into the muscle or vein. It may also be prescribed as tablets or a liquid suspension. Your doctor will advise you on the best method of taking Benzylpénicilline.
What are the side effects of Benzylpénicilline?
The most common side effects of Benzylpénicilline include nausea, vomiting, diarrhea, and rash. Other possible side effects include dizziness, headache, fever, and stomach pain.
Is Benzylpénicilline safe to take during pregnancy?
It is generally considered safe for pregnant women to take Benzylpénicilline, however it is important to discuss any potential risks with your doctor before taking this medication.
What should I do if I forget to take a dose of Benzylpénicilline?
If you forget to take a dose of Benzylpénicilline, take it as soon as you remember and then continue as normal. Do not take a double dose to make up for a forgotten dose.
Can I drink alcohol while taking Benzylpénicilline?
It is generally not advised to drink alcohol while taking Benzylpénicilline as it can cause further nausea and can increase the risk of side effects. It is best to avoid alcohol until you have finished taking the course.
Does Benzylpénicilline interact with any other medications?
Yes, Benzylpénicilline can interact with other medications, including antacids, probenecid, and certain blood thinners. It is important to tell your doctor or pharmacist about any other medications that you are taking before starting Benzylpénicilline.
Does Benzylpénicilline cause any long-term effects?
No, there have been no reports of long-term effects caused by Benzylpénicilline. It is usually safe for long-term use if taken as prescribed.
How long should I take Benzylpénicilline for?
Benzylpénicilline is usually taken for a short period of time, usually no more than 5-7 days. It is important to finish the course of medication as prescribed in order for it to work effectively.
How long does it take for Benzylpénicilline to work?
The effects of Benzylpénicilline should begin to be felt after a few days of taking the medication. However, it is important to finish the course of medication to ensure that the infection does not return.
Can Benzylpénicilline cause allergic reactions?
Yes, some people may experience an allergic reaction to Benzylpénicilline. Signs of an allergic reaction include rash, itching, swelling, and difficulty breathing.
What should I do if I experience an allergic reaction to Benzylpénicilline?
If you experience any of the symptoms of an allergic reaction, it is important to stop taking the medication and seek medical attention immediately.
Can I take Benzylpénicilline if I am breastfeeding?
It is usually safe for breastfeeding women to take Benzylpénicilline, however it is important to discuss any potential risks with your doctor before taking this medication.
Is Benzylpénicilline suitable for children?
Yes, Benzylpénicilline is suitable for children. However, it is important to consult with a doctor before giving Benzylpénicilline to a child, as the dosage may need to be adjusted.
Can I take Benzylpénicilline with other antibiotics?
No, it is not generally recommended to take Benzylpénicilline with other antibiotics as this can increase the risk of side effects and reduce the effectiveness of the medication.
What should I do if I experience any side effects while taking Benzylpénicilline?
If you experience any unpleasant side effects while taking Benzylpénicilline, it is important to discuss these with your doctor as soon as possible. They can advise you on the best course of action.
What should I do if I miss a dose of Benzylpénicilline?
If you miss a dose of Benzylpénicilline, take it as soon as you remember and then continue as normal. Do not take a double dose to make up for a forgotten dose.
What is the most common side effect of Benzylpénicilline?
The most common side effect of Benzylpénicilline is nausea. Other side effects may include vomiting, diarrhea, rash, dizziness, headache, fever, and stomach pain.
Is there anything I should avoid while taking Benzylpénicilline?
It is generally not advised to drink alcohol while taking Benzylpénicilline as it can cause further nausea and can increase the risk of side effects. It is also important to avoid taking any other medications without consulting your doctor first.
What should I do if I experience a severe rash while taking Benzylpénicilline?
If you experience a severe rash while taking Benzylpénicilline, it is important to stop taking the medication and seek medical advice immediately.
Can I take other medications while taking Benzylpénicilline?
You should not take any other medications without consulting your doctor or pharmacist first. Benzylpénicilline can interact with certain medications, such as antacids, probenecid, and certain blood thinners.
Can Benzylpénicilline be used to treat viral infections?
No, Benzylpénicilline can only be used to treat bacterial infections. It should not be taken for viral infections, as this can increase the risk of side effects.
What should I do if I experience an upset stomach while taking Benzylpénicilline?
If you experience an upset stomach while taking Benzylpénicilline, it is important to speak to your doctor or pharmacist. They may advise you to take an antacid or make other changes to your medication regimen.
Can Benzylpénicilline cause drowsiness?
Yes, Benzylpénicilline can cause drowsiness in some people. If you experience drowsiness, it is important to avoid operating machinery or driving until this side effect has passed.
What should I do if I experience a headache while taking Benzylpénicilline?
If you experience a headache while taking Benzylpénicilline, it is important to speak to your doctor or pharmacist. They may advise you to take a painkiller or make other changes to your medication regimen.
Is it safe to take Benzylpénicilline long-term?
Yes, it is usually safe for long-term use if taken as prescribed. However, it is important to discuss any potential risks with your doctor before taking this medication.
Does Benzylpénicilline affect blood sugar levels?
No, there have been no reports of Benzylpénicilline affecting blood sugar levels. However, it is important to monitor your blood sugar levels while taking this medication.
Can Benzylpénicilline affect my kidneys?
Yes, long-term use of Benzylpénicilline may cause kidney damage. It is important to discuss any potential risks with your doctor before taking this medication.
Can taking Benzylpénicilline cause yeast infections?
Yes, taking Benzylpénicilline may increase the risk of developing yeast infections. If you experience any itching, soreness, or irritation, it is important to speak to your doctor as soon as possible.
Can I take Benzylpénicilline if I have a kidney or liver disease?
Yes, if you have a kidney or liver disease, it is usually safe to take Benzylpénicilline. However, it is important to discuss any potential risks with your doctor before taking this medication.
Can I take Benzylpénicilline if I have an allergy to penicillin?
No, if you have an allergy to penicillin, it is not advisable to take Benzylpénicilline. Speak to your doctor about alternative treatments or to discuss the risks and benefits further.
Can I take Benzylpénicilline if I am breastfeeding?
It is usually safe for breastfeeding women to take Benzylpénicilline, however it is important to discuss any potential risks with your doctor before taking this medication.
Can I take Benzylpénicilline if I am taking other medications?
It is important to tell your doctor or pharmacist about any other medications that you are taking before starting Benzylpénicilline, as it is not recommended to take Benzylpénicilline with other medications. Your doctor can advise you on the best course of action.
How long does it take for the effects of Benzylpénicilline to wear off?
The effects of Benzylpénicilline usually last for several days after the course of medication has been completed. It is important to finish the course of medication as prescribed to ensure that the infection does not return.
Do I need to avoid any food or drink while taking Benzylpénicilline?
It is generally not advised to drink alcohol while taking Benzylpénicilline as it can cause further nausea and can increase the risk of side effects. You do not need to avoid any other food or drink while taking this medication.
Do I need to take any precautions while taking Benzylpénicilline?
Yes, it is important to take the precautions outlined by your doctor while taking Benzylpénicilline. This may include avoiding certain activities, such as operating machinery or driving, and avoiding certain medications or alcohol.
Is there any food or medication that I should avoid while taking Benzylpénicilline?
Yes, it is important to avoid taking other medications without consulting your doctor first, as Benzylpénicilline can interact with certain medications, such as antacids, probenecid, and certain blood thinners. It is also important to avoid drinking alcohol while taking Benzylpénicilline.