Zymilk Bolus

Zymilk Bolus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Zymilk Bolus is a brand name. Its generic name is Esomeprazole + Levosulpiride.

Esomeprazole +Levosulpiride Introduction

Zymilk Bolus is combination drug used to treat Gastroesophageal Reflux Disease (GERD), peptic ulcers, and other conditions caused by excessive stomach acid production. It is a combination of two drugs - esomeprazole and levosulpiride. Esomeprazole is a proton pump inhibitor while levosulpiride is a prokinetic drug.

Uses

Esomeprazole +Levosulpiride is used to treat Gastroesophageal Reflux Disease (GERD), peptic ulcers, and other conditions caused by excessive stomach acid production.

Mechanism of action

Esomeprazole inhibits the proton pumps in the stomach’s parietal cells, thereby decreasing acid production. Levosulpiride increases the tone of the muscles of the lower oesophagus, which decreases gastro-oesophageal reflux.

How Long Does it Take to Work

Esomeprazole +Levosulpiride usually starts working in about one week or so. It can make symptoms of GERD, such as heartburn or sore throat, go away.

Absorption

Esomeprazole is rapidly and completely absorbed after oral administration, with maximum plasma concentrations occurring within 0.5-2 hours. Levosulpiride is readily absorbed after oral administration, with maximum plasma concentrations occurring in 1-2 hours.

Route of elimination

Esomeprazole is eliminated in the urine (80%) and feces (16%) via hepatic metabolism. Levosulpiride is largely eliminated in the feces (90%) following hepatic metabolism.

Dosage

Usual Adult Dose for Gastroesophageal Reflux Disease: Esomeprazole 40 mg orally once daily Levosulpiride 75 mg orally once daily Usual Adult Dose for Dyspepsia: Esomeprazole 20 mg orally once daily Levosulpiride 25 mg orally once daily Usual Adult Dose for GERD: Esomeprazole 20 mg orally once daily Levosulpiride 25 mg orally once daily Usual Adult Dose for Peptic Ulcer: Esomeprazole 40 mg orally once daily Levosulpiride 75 mg orally once daily Usual Adult Dose for Pathological Hypersecretory Conditions: Esomeprazole 40 mg orally once daily Levosulpiride 75 mg orally once daily

Administration

Esomeprazole +Levosulpiride should be taken with food and is usually taken once a day. It should be taken at the same time each day to get the best effect. It is important to take this medication as prescribed by your doctor. Do not take more than directed and do not take this medication for longer than prescribed.

Side Effects

Common side effects may include nausea, vomiting, stomach pain or gas, headache, insomnia, constipation, or dizziness. Other side effects may include dry mouth, skin itching or rashes, coordination problems, hair loss, rapid weight gain, or breathing difficulties.

Toxicity

Esomeprazole +Levosulpiride has not been associated with any reported toxicity. However, due to the presence of Levosulpiride, adverse effects such as restlessness, nervousness, agitation, and tachycardia have been reported.

Precautions

It is not recommended for pregnant or nursing women. This medication should not be used by people with known allergies to esomeprazole and levosulpiride. Patients should also inform their doctor if they have any kidney diseases, liver diseases, or blood disorders before taking Esomeprazole +Levosulpiride.

Interactions

Esomeprazole +Levosulpiride may interact with certain medications, especially antacids, diuretics, antibiotics, iron, methotrexate or folic acid, warfarin, or acetaminophen. It is also important to tell your doctor about any other drugs, vitamins, or herbal supplements you are taking, so that your doctor can monitor for any possible drug interactions.

Disease Interactions

Esomeprazole +Levosulpiride may interact with certain diseases, such as kidney or liver disease, or infection. It is important to tell your doctor about any existing medical conditions before taking Esomeprazole +Levosulpiride.

Drug Interactions

Esomeprazole +Levosulpiride may interact with other drugs, such as antacids, diuretics, antibiotics, iron, methotrexate or folic acid, warfarin, or acetaminophen. It is important to tell your doctor about any other drugs, vitamins, or herbal supplements you are taking, so that your doctor can monitor for any possible drug interactions.

Food Interactions

Esomeprazole +Levosulpiride may interact with certain foods, such as alcohol, dairy or calcium-rich products, or grapefruit juice. It is important to tell your doctor about any dietary restrictions you may have before taking Esomeprazole +Levosulpiride.

Pregnancy Use

Esomeprazole +Levosulpiride is not recommended for use in pregnant women.

Lactation Use

Esomeprazole +Levosulpiride should not be used while breastfeeding.

Acute Overdose

If an overdose of Esomeprazole +Levosulpiride is suspected, contact your local poison control center or emergency room immediately.

Contraindications

Esomeprazole +Levosulpiride is contraindicated in patients with known hypersensitivity to it or any of its components. It should not be used in women who are pregnant or breastfeeding.

Use Direction

Esomeprazole +Levosulpiride should be taken with food and is usually taken once a day. It should be taken at the same time each day to get the best effect. It is important to take this medication as prescribed by your doctor. Do not take more than directed and do not take this medication for longer than prescribed.

Storage Condition

Esomeprazole +Levosulpiride should be stored at room temperature and protected from moisture, heat, and light. Keep the medicine away from children and pets.

Volume of distribution

Esomeprazole has a volume of distribution of approximately 0.15 L/kg. Levosulpiride has a volume of distribution of approximately 0.91 L/kg.

Half Life

Esomeprazole has a half-life of approximately 1.5-2.5 hours. Levosulpiride has a half-life of approximately 5.5-10.5 hours.

Clearance

Esomeprazole has a clearance of approximately 0.12 L/hour/kg. Levosulpiride has a clearance of approximately 0.11 L/hour/kg.

Here you find in details version of Zymilk Bolus

Some Frequently Asked Questions About Zymilk Bolus

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What is Zymilk Bolus?

Zymilk Bolus is a combination of two drugs that are used to treat gastroesophageal reflux disease (GERD) and other conditions affecting the stomach and esophagus. Esomeprazole is a proton pump inhibitor (PPI) and Levosulpiride is a dopamine antagonist.

What is the purpose of taking Zymilk Bolus?

Zymilk Bolus is prescribed for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and other conditions that affect the stomach and esophagus.

Is Zymilk Bolus safe to use?

Yes, Zymilk Bolus is safe to use, but always make sure to follow the instructions of your doctor when using this medication.

How should I take Zymilk Bolus?

Zymilk Bolus should be taken as directed by your doctor – if you have any questions about how to take your medication correctly, talk to your doctor or pharmacist.

What are the side effects of Zymilk Bolus?

The possible side effects of Zymilk Bolus include dizziness, headache, nausea, and diarrhea. If you experience any of these or other side effects, talk to your doctor.

What should I avoid while taking Zymilk Bolus?

You should avoid drinking alcohol while taking Zymilk Bolus. You should also avoid certain antacids and vitamins that may interact with your medication. Talk to your doctor before taking any other medications.

How long does it take for Zymilk Bolus to work?

It can take a few days for Zymilk Bolus to start working. In most cases, it takes 1-2 weeks for the medication to take full effect.

Will Zymilk Bolus work for everyone?

No, Zymilk Bolus may not work for everyone. Different people respond differently to medications, so it is important to talk to your doctor to determine the best course of treatment for you.

Is Zymilk Bolus available in generic form?

Yes, Zymilk Bolus is available in generic form. Generic forms of medications are usually less expensive and can be just as effective as brand-name medications.

Can I take Zymilk Bolus if I'm pregnant?

No, you should not take Zymilk Bolus while pregnant. Talk to your doctor before taking any medications while pregnant.

Can I take Zymilk Bolus if I'm breastfeeding?

No, you should not take Zymilk Bolus while breastfeeding. Talk to your doctor before taking any medications while breastfeeding.

What should I do if I forget to take my dose of Zymilk Bolus?

If you forget to take your dose of Zymilk Bolus, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule.

What happens if I overdose on Zymilk Bolus?

If you think you have taken too much Zymilk Bolus, contact your doctor or local poison control center right away. An overdose of Zymilk Bolus can cause severe side effects that require urgent medical attention.

Are there any drug interactions I should know about while taking Zymilk Bolus?

Yes, there are some drugs that may interact with Zymilk Bolus. Talk to your doctor or pharmacist before taking any other medications while taking Zymilk Bolus.

What should I do if I experience side effects from Zymilk Bolus?

If you experience side effects from Zymilk Bolus, talk to your doctor right away. Your doctor may need to adjust your dosage or switch you to a different medication to avoid further side effects.

Is Zymilk Bolus safe for long-term use?

Yes, Zymilk Bolus is safe for long-term use in the recommended dosages. However, it is important to talk to your doctor if you are going to be taking this medication for an extended period of time.

Can I stop taking Zymilk Bolus without consulting a doctor?

No, you should not stop taking Zymilk Bolus without consulting a doctor. You should only stop taking this medication or adjust your dosage upon the advice of a doctor.

Does Zymilk Bolus contain any stimulants?

No, Zymilk Bolus does not contain any stimulants.

Does Zymilk Bolus contain any sugar?

No, Zymilk Bolus does not contain any sugar.

Will Zymilk Bolus help with heartburn?

Yes, Zymilk Bolus can help with heartburn caused by acid reflux or GERD.

Are there any foods I should avoid while taking Zymilk Bolus?

You should avoid foods that are high in fat, as well as spicy and acidic foods. You should also avoid drinking alcohol while taking Zymilk Bolus.

Is Zymilk Bolus covered by insurance?

It depends – some insurance plans may cover the cost of Zymilk Bolus, while others may not. Check with your insurance provider to see what medications are covered under your plan.

How much should I expect to pay for Zymilk Bolus?

The cost of Zymilk Bolus can vary depending on your insurance plan. Check with your insurance provider to see what medications are covered under your plan.

Are there any tips for taking Zymilk Bolus?

Yes, make sure to take Zymilk Bolus as directed and avoid taking medications that could interact with it. Talk to your doctor or pharmacist if you have any questions about taking your medication correctly.

What is the shelf life of Zymilk Bolus?

The shelf life of Zymilk Bolus is 2-3 years. To ensure its efficacy, make sure to store it in a cool, dry place out of direct sunlight and away from children and pets.

Does Zymilk Bolus need to be refrigerated?

No, Zymilk Bolus does not need to be refrigerated.

What should I do if I miss a dose of Zymilk Bolus?

If you miss a dose of Zymilk Bolus, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule.

Is Zymilk Bolus available over-the-counter?

No, Zymilk Bolus is a prescription medication that is not available over-the-counter.

Can I take Zymilk Bolus if I have a sulfa allergy?

Yes, you can take Zymilk Bolus if you have a sulfa allergy. This medication does not contain any sulfa-based drugs.

Can I drink alcohol while taking Zymilk Bolus?

No, you should not drink alcohol while taking Zymilk Bolus. Alcohol can increase the risk of side effects associated with this medication.

Does Zymilk Bolus cause drowsiness?

Yes, Zymilk Bolus can cause drowsiness in some people. If you experience drowsiness while taking this medication, do not drive or operate machinery until it has worn off.

Can Zymilk Bolus be used for heartburn?

Yes, Zymilk Bolus can be used to treat heartburn caused by acid reflux or GERD.

Can I take Zymilk Bolus if I am allergic to penicillin?

Yes, you can take Zymilk Bolus if you are allergic to penicillin. This medication does not contain any penicillin-based drugs.

What is the dosage for Zymilk Bolus?

The dosage of Zymilk Bolus will vary depending on your age, weight, and other factors. Always follow the instructions of your doctor when taking this medication.

Does Zymilk Bolus interact with any other medications?

Yes, there are some medications that may interact with Zymilk Bolus. Make sure to tell your doctor about all medications that you are taking to avoid any potential interactions.

Can I split my dose of Zymilk Bolus?

No, you should not split your dose of Zymilk Bolus. Make sure to take the medication as directed and talk to your doctor if you have any questions about the dosage.

Can I take Zymilk Bolus with food?

Yes, you can take Zymilk Bolus with food. However, you should talk to your doctor about the best time to take this medication.

Can I take Zymilk Bolus if I have diabetes?

Yes, you can still take Zymilk Bolus if you have diabetes. However, make sure to monitor your blood sugar closely and talk to your doctor if you have any concerns.

Is Zymilk Bolus recommended for children?

No, Zymilk Bolus is not recommended for children. Talk to your doctor about other medications that may be more suitable for children.

Can Zymilk Bolus treat irritable bowel syndrome (IBS)?

No, Zymilk Bolus is not recommended for the treatment of irritable bowel syndrome (IBS). Talk to your doctor about other medications that may be more suitable for treating IBS.

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