Abidox M

Abidox M Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Abidox M is a brand name. Its generic name is Doxofylline + Montelukast.

Introduction

Doxofylline and Montelukast is used in the treatment of airway diseases like bronchial asthma. Doxofylline is a xanthine derivative and a bronchodilator. Montelukast is a leukotrien modulation agent. When used together, the two drugs work synergistically and are more effective in treating airway diseases.

Uses

Doxofylline and Montelukast is used to treat bronchial asthma and to prevent or reduce the severity of exercise-induced bronchoconstriction. It can also be used to treat other airway diseases such as allergic rhinitis.

Mechanism of Action

Doxofylline works as a bronchodilator. It works by blocking the chemoattractant receptor of the smooth muscle leading to a relaxation of the smooth muscles. Montelukast inhibits the production of leukotriene, which is a mediator that contributes to bronchoconstriction.

How Long Does it Take to Work?

The effects of the combination of Doxofylline and Montelukast can typically be felt within 1-2 hours of administration.

Absorption

Doxofylline is rapidly and almost completely absorbed from the gastrointestinal tract. Montelukast is also rapidly absorbed from the gastrointestinal tract.

Route of Elimination

Doxofylline is rapidly metabolized and is eliminated in the urine as metabolites. Montelukast is almost completely metabolized and is eliminated mainly in the feces and to a lesser extent in the urine.

Dosage

The dosage of Doxofylline and Montelukast is dependent on the individual patient and the severity of the condition. The typical dose of Doxofylline is 400 milligrams twice a day. The typical dose of Montelukast is 10 milligrams once daily.

Administration

Doxofylline and Montelukast can be taken orally or by inhalation. For oral administration, take the tablets with a full glass of water on an empty stomach, at least one hour before or two hours after a meal. For inhalation, use an inhaler or a nebulizer.

Side Effects

The most common side effects of Doxofylline and Montelukast include headache, nausea, vomiting, dizziness, insomnia, increased sweating, and rash. Other less common side effects include palpitations, chest pain, weakness, shortness of breath, and an increase in blood pressure.

Toxicity

The toxicity potential of Doxofylline and Montelukast is low. Overdose of the drug may lead to restlessness, difficulty in breathing, and other signs of toxicity. In case of an overdose, contact your doctor immediately.

Precautions

It is important to take Doxofylline and Montelukast as prescribed by the doctor. Do not change the dose or stop using the drug without consulting your doctor. If you are pregnant or breastfeeding, inform your doctor before taking the drug. Do not take the drug if you are allergic to any of the ingredients.

Interactions

Doxofylline and Montelukast may interact with other drugs, including warfarin, antifungals, sedatives, antibiotics, diuretics, anticonvulsants, antipsychotics, antivirals, and others. Inform your doctor about all medications you are taking before starting on Doxofylline and Montelukast.

Disease Interaction

Doxofylline and Montelukast may not be suitable for people with liver, kidney, or heart disease. It is also contraindicated in patients with a history of bronchospasm. In case of any underlying disease, inform your doctor before taking the drug.

Drug Interaction

Doxofylline and Montelukast may interact with other drugs. These include warfarin, antifungals, sedatives, antibiotics, diuretics, anticonvulsants, antipsychotics, antivirals, and others. Inform your doctor of all medications you are taking before starting on Doxofylline and Montelukast.

Food Interactions

Avoid alcohol and caffeinated beverages while taking Doxofylline and Montelukast. Grapefruit and grapefruit juice may also interact with the drug and hence should be avoided. Inform your doctor about what you eat before taking the drug.

Pregnancy Use

Doxofylline and Montelukast should not be used during pregnancy unless it is absolutely essential and the benefits outweigh the risks. If you are pregnant, inform your doctor immediately.

Lactation Use

Doxofylline and Montelukast should not be used during breastfeeding unless it is absolutely essential and the benefits outweigh the risks. Inform your doctor if you are breastfeeding before taking the drug.

Acute Overdose

An acute overdose may cause restlessness, difficulty in breathing, and other signs of toxicity. In case of an overdose, contact your doctor immediately.

Contraindication

Doxofylline and Montelukast should not be used in patients with a known allergy to the drug. It is also contraindicated in patients with a history of bronchospasm or in those with liver, kidney, or heart disease.

Use Direction

Doxofylline and Montelukast should be taken as directed by the doctor. The typical dose of Doxofylline is 400 milligrams twice a day. The typical dose of Montelukast is 10 milligrams once daily. Take the tablets with a full glass of water on an empty stomach, at least one hour before or two hours after a meal.

Storage Condition

Doxofylline and Montelukast should be stored at room temperature, away from direct heat and sunlight. Keep out of reach of children.

Volume of Distribution

The volume of distribution of Doxofylline and Montelukast is unknown. However, the drugs are distributed throughout the body and can reach all organs and tissue.

Half Life

The half life of Doxofylline is 3.6 hours and the half life of Montelukast is 3-6 hours.

Clearance

Doxofylline is rapidly metabolized and is eliminated in the urine as metabolites. Montelukast is almost completely metabolized and is eliminated mainly in the feces and to a lesser extent in the urine.

Here you find in details version of Abidox M

Some Frequently Asked Questions About Abidox M

What is Doxofylline+Montelukast?

Doxofylline+Montelukast is an oral medication that is used to treat asthma and other respiratory conditions, including chronic obstructive pulmonary disease (COPD). The two active ingredients, doxofylline and montelukast, work together to reduce inflammation in the lungs and increase airflow.

How does Doxofylline+Montelukast work?

The two active ingredients in Doxofylline+Montelukast work together to reduce inflammation and improve breathing. Doxofylline is a bronchodilator, which relaxes the muscles that surround the airways and allows more air to flow through. Montelukast is an anti-inflammatory medication that helps to reduce swelling in the lungs and make breathing easier.

How long does it take for Doxofylline+Montelukast to start working?

Doxofylline+Montelukast usually starts working within 2 to 4 hours of taking it. If you do not see any improvement in your symptoms after taking the medication for several days, please contact your healthcare provider for further assessment.

Is Doxofylline+Montelukast safe for long-term use?

Yes, Doxofylline+Montelukast is generally safe and effective for long-term use. If you have any concerns about the safety of long-term use of Doxofylline+Montelukast, please consult your healthcare provider.

Can I take Doxofylline+Montelukast while pregnant?

It is not recommended to take Doxofylline+Montelukast while pregnant as there is not enough known about the safety of the drug during pregnancy. If you are pregnant, please discuss alternative treatment options with your healthcare provider.

Can I take Doxofylline+Montelukast with other medications?

Yes, it is generally safe to take Doxofylline+Montelukast with other medications. However, it is important to discuss all medications and supplements you are taking with your healthcare provider before taking Doxofylline+Montelukast.

What are the side effects of Doxofylline+Montelukast?

Common side effects of Doxofylline+Montelukast include headache, nausea, diarrhea, and insomnia. More serious side effects may include fever, joint pain, rash, or difficulty breathing. If you experience any side effects, please contact your healthcare provider.

Can I drink alcohol while taking Doxofylline+Montelukast?

It is not recommended to drink alcohol while taking Doxofylline+Montelukast due to the potential for interactions between the two. Please consult your healthcare provider about drinking alcohol while taking Doxofylline+Montelukast.

Is Doxofylline+Montelukast covered by insurance?

The cost of Doxofylline+Montelukast is typically covered by most insurance plans. However, coverage may vary based on your insurance provider. Please contact your insurance provider to get a better understanding of your coverage and potential out-of-pocket costs.

Can I stop taking Doxofylline+Montelukast suddenly?

No, it is not recommended to stop taking Doxofylline+Montelukast suddenly without consulting your healthcare provider. Abruptly stopping Doxofylline+Montelukast can cause a temporary worsening of your symptoms and increase the risk of side effects.

What is the correct way to take Doxofylline+Montelukast?

Doxofylline+Montelukast is typically taken once daily. It is important to take your medication at the same time every day. Taking it with food may help to reduce the chance of stomach upset. It is important to take your medication as prescribed and not to miss any doses.

Is Doxofylline+Montelukast available in generic form?

Yes, Doxofylline+Montelukast is available in generic form. Generic versions of Doxofylline+Montelukast may be cheaper than the brand-name version. However, generic versions may not be as effective as the brand-name version.

Can children take Doxofylline+Montelukast?

Doxofylline+Montelukast is approved for use in children over the age of six. However, it is important to consult a healthcare provider before the medication is administered to a child.

Are there any dietary restrictions with Doxofylline+Montelukast?

No, there are no known dietary restrictions associated with Doxofylline+Montelukast. However, it is important to consult your healthcare provider about any dietary changes while taking the medication.

Can I take Doxofylline+Montelukast if I have kidney disease?

Doxofylline+Montelukast should not be taken if you have kidney disease, as it can worsen your condition. Please contact your healthcare provider for other treatment options if you have kidney disease.

Will Doxofylline+Montelukast cause weight gain?

Weight gain is not a known side effect of Doxofylline+Montelukast. However, if you experience weight gain while taking the medication, please contact your healthcare provider.

Does Doxofylline+Montelukast cause drowsiness?

Drowsiness is not a common side effect of Doxofylline+Montelukast. However, if you experience drowsiness after taking the medication, please contact your healthcare provider.

How should I store Doxofylline+Montelukast?

Doxofylline+Montelukast should be stored at room temperature in a dry and dark place. Do not keep the medication in direct sunlight or in a humid environment such as the bathroom.

Can I take Doxofylline+Montelukast if I have elevated liver enzymes?

It is not recommended to take Doxofylline+Montelukast if you have elevated liver enzymes. Please consult your healthcare provider about other treatment options if you have elevated liver enzymes.

Can I take an over-the-counter medication while taking Doxofylline+Montelukast?

Yes, it is generally safe to take over-the-counter medications while taking Doxofylline+Montelukast. However, it is important to consult your healthcare provider before taking any new medications or supplements.

Can I take Doxofylline+Montelukast if I am breastfeeding?

It is not recommended to take Doxofylline+Montelukast while breastfeeding, as it is not known if the medication passes into breast milk. Please consult your healthcare provider about other treatment options if you are breastfeeding.

Can Doxofylline+Montelukast be used to treat COPD?

Yes, Doxofylline+Montelukast can be used to treat COPD. Studies have shown that the two active ingredients in Doxofylline+Montelukast can reduce inflammation and improve breathing in people with COPD.

What is the maximum dose of Doxofylline+Montelukast?

The maximum recommended daily dose of Doxofylline+Montelukast is 600 mg. It is important to take the medication as prescribed by your healthcare provider and not to exceed the recommended daily dose.

Can I take Doxofylline+Montelukast with certain food?

It is generally safe to take Doxofylline+Montelukast with food. Taking the medication with food may reduce the chance of stomach upset. However, it is important to speak to your healthcare provider if you have any questions about taking Doxofylline+Montelukast with certain foods.

Should I take Doxofylline+Montelukast with other medications?

It is generally safe to take Doxofylline+Montelukast with other medications. However, it is important to discuss any other medications and supplements you are taking with your healthcare provider before taking Doxofylline+Montelukast.

Does Doxofylline+Montelukast interact with certain foods?

No, there are no known interactions between Doxofylline+Montelukast and certain foods. However, it is important to speak to your healthcare provider if you have any questions about taking Doxofylline+Montelukast with certain foods.

Can Doxofylline+Montelukast cause diarrhea?

Yes, diarrhea is a known side effect of Doxofylline+Montelukast. If you experience diarrhea while taking the medication, please contact your healthcare provider.

Can I take Doxofylline+Montelukast if I have a heart condition?

It is not recommended to take Doxofylline+Montelukast if you have a heart condition, as the medication can worsen your condition. Please consult your healthcare provider about other treatment options if you have a heart condition.

Can Doxofylline+Montelukast cause insomnia?

Yes, insomnia is a known side effect of Doxofylline+Montelukast. If you experience insomnia while taking the medication, please contact your healthcare provider.

Can Doxofylline+Montelukast cause allergies?

Allergic reactions to Doxofylline+Montelukast are rare, but they can occur. If you experience any allergic reactions after taking the medication, please contact your healthcare provider.

Can I take Doxofylline+Montelukast if I have diabetes?

Yes, Doxofylline+Montelukast can be taken even if you have diabetes. However, it is important to closely monitor your blood sugar while taking this medication. Please consult your healthcare provider regularly to ensure proper management of your diabetes.

Can I take Doxofylline+Montelukast if I am a smoker?

Yes, Doxofylline+Montelukast can be taken even if you are a smoker. However, it is important to discuss any changes in your smoking habits with your healthcare provider before taking Doxofylline+Montelukast.

Can Doxofylline+Montelukast cause dizziness?

Dizziness is not a common side effect of Doxofylline+Montelukast. However, if you experience dizziness after taking the medication, please contact your healthcare provider.

Can I take Doxofylline+Montelukast with oral contraceptives?

Yes, it is generally safe to take Doxofylline+Montelukast with oral contraceptives. However, it is important to discuss any changes in your oral contraceptive use with your healthcare provider before taking Doxofylline+Montelukast.

Can I take Doxofylline+Montelukast with antacids?

Yes, it is generally safe to take Doxofylline+Montelukast with antacids. However, it is important to discuss any changes in your antacid use with your healthcare provider before taking Doxofylline+Montelukast.

Does Doxofylline+Montelukast cause a dry mouth?

Dry mouth is not a common side effect of Doxofylline+Montelukast. However, if you experience a dry mouth after taking the medication, please contact your healthcare provider.

Will Doxofylline+Montelukast cause blurred vision?

Blurred vision is not a known side effect of Doxofylline+Montelukast. However, if you experience blurred vision after taking