Zaluk
Zaluk Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Zaluk is a brand name. Its generic name is Zafirlukast.
etcIntroduction
Zaluk is an orally administered leukotriene receptor antagonist used to treat asthma. It blocks leukotrienes, naturally occurring substances in your body, lungs and airways. This prevents bronchoconstriction, inflammation and increased mucus in your airways caused by leukotrienes.Uses For
Zaluk is used to prevent asthma attacks in adults and children ages 5 and over. It helps reduce symptoms, such as wheezing, shortness of breath, and chest tightness. Zaluk is not a rescue medication and should not be taken during an acute asthma episode.Mechanism of Action
Zaluk works by inhibiting leukotriene receptor binding. It blocks the binding of leukotriene C4, D4, and E4 (LTC4, LTD4, and LTE4) to the cysteinyl leukotriene receptors on cells in the body. By blocking these receptors, Zaluk prevents leukotrienes from activating the cells and causing inflammation.How Long Does it Take to Work?
Zaluk usually takes 2 to 4 days to reduce symptoms of asthma. Ten percent of patients may require up to two weeks before they show any symptom improvement.Absorption
Zaluk is rapidly absorbed after oral administration, with peak plasma concentrations occurring three hours after administration.Route of Elimination
Zaluk is eliminated primarily by the kidneys. Ninety-one percent of administered oral doses are excreted in the urine within five days.Dosage
Zaluk is supplied as 10 mg tablets and should be taken twice daily, with or without food. The usual dose for adults and children over 12 years of age is 20 mg twice daily. For children 5-11 years of age, the usual dose is 10 mg twice daily.Administration
Zaluk should be administered orally, with or without food. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablets.Side Effect
The most common side effects of Zaluk include upper respiratory tract infection, nausea, sore throat, dizziness, abdominal pain, headache, and diarrhea.Toxicity
Zaluk has no specific antidote and is not expected to cause serious toxicity. Overdose of Zaluk may cause nausea, vomiting, and abdominal pain.Precautions
Zaluk should be used with caution in patients with liver impairment, as it may increase the risk of liver damage. The safety and effectiveness of Zaluk have not been established in patients younger than 5 years of age.Interactions
Zaluk may interact with certain medications such as theophylline, warfarin, cyclosporine, and oral contraceptives.Disease Interactions
Zaluk may not be suitable for patients with certain conditions, such as liver or kidney disease.Drug Interactions
Zaluk may interact with other drugs, such as warfarin, cyclosporine, and oral contraceptives. Patients should consult their healthcare provider before taking any new medications while taking Zaluk.Food Interactions
There are no known food interactions with Zaluk. It is best to take it with food, but it may be taken with or without food.Pregnancy Use
Women who are pregnant should not use Zaluk. It is not known if this medication passes into breast milk.Lactation Use
Zaluk should be avoided in nursing mothers as it is not known if this medication passes into breast milk.Acute Overdose
There is no known antidote for Zaluk and acute overdoes is not expected to cause serious toxicity. Symptoms of overdose may include nausea, vomiting, and abdominal pain.Contraindication
Zaluk should not be used in patients who are hypersensitive to the drug or its components.Use Direction
Zaluk should be taken exactly as prescribed. Follow the instructions on the prescription label. Do not take it in larger amounts or for longer than recommended.Storage Condition
Store Zaluk at room temperature away from heat and light. Keep the container tightly closed when not in use.Volume of Distribution
The volume of distribution for Zaluk is not known.Half Life
The half-life of Zaluk is approximately 5 hours.Clearance
The clearance of Zaluk from the body is not known.Here you find in details version of Zaluk
Some Frequently Asked Questions About Zaluk
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