Velofix Capsule 200 mg

Velofix Capsule 200 mg Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Velofix Capsule 200 mg is a brand name. Its generic name is Cefixime Trihydrate.

Introduction

Velofix Capsule 200 mg is an orally administered third-generation cephalosporin antibiotic. It is used to treat infections caused by certain bacteria. Velofix Capsule 200 mg is a semisynthetic cephalosporin and is chemically designated as (6R,7R)-7-[2-([(2-Amino-4-thiazolyl)thio]methyl)[1,3]-thiazol-4-yl]-3-[(2,3,4-trihydroxy-1-methylbutyl)thio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate.

Uses For

Velofix Capsule 200 mg is indicated for the treatment of adults and pediatric patients six months and older with the following infections caused by susceptible isolates of the designated microorganisms:

Un Complicated Urinary Tract Infections caused by Escherichia coli and Proteus mirabilis
Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
Un Complicated gonorrhea caused by Neisseria gonorrhoeae

Mechanism of Action

Velofix Capsule 200 mg as with other cephalosporins, cefixime exerts antibacterial activity by inhibiting bacterial cell wall synthesis. Cefixime binds to and inactivates penicillin-binding proteins (PBPs) which are located inside bacterial cell walls. This ultimately results in the weakening of the bacterial cell wall, leading to bacterial cell death.

How Long Does It Take To Work

The time for cefixime to take effect can depend on the infection being treated and the individual being treated. Cefixime typically begins to work within 24 to 48 hours of beginning treatment. Your symptoms should begin to improve shortly after starting cefixime, however you should continue taking the drug until you finish your prescribed course.

Absorption

Following oral administration, cefixime is rapidly and extensively absorbed, with peak concentrations occurring 2 to 4 hours after administration. Bioavailability in normal adults is approximately 50%. Cefixime is rapidly distributed throughout the body; approximately 40% is bound to plasma proteins.

Route of Elimination

Cefixime is excreted primarily by the renal route with only 20–30% of the unchanged drug appearing in the urine. The remainder of the drug is excreted as inactive metabolites and in the feces.

Dosage

The recommended adult oral dose of cefixime is 400mg as a single dose. For urinary tract infections, gonorrhea, and otitis media the recommended dosage is 8mg/kg in two divided doses daily. The recommended pediatric oral dose of cefixime is 8mg/kg given as a single dose. For chronic bronchitis the recommended dosage is 400mg twice daily for 5 to 10days.

Administration

Cefixime is available as a tablet, dispersible tablet, suspension, and chewable tablet. It should be taken with food to reduce the magnitude of gastrointestinal upset. Depending on which form you have, cefixime may be taken with a full glass of water or taken with food.

Side Effect

Common side effects of cefixime include nausea, stomach pain, diarrhea, headache, or dizziness. These symptoms should improve as your body adjusts to the medication, although if they are severe they may require medical attention.

Toxicity

The toxic dose of cefixime is not well established in humans, however in animal studies high doses of cefixime were found to be tolerated without any significant signs of toxicity. Serious adverse effects from large doses of cefixime are unlikely.

Precaution

Patients taking cefixime should avoid taking large amounts of dairy products (including milk, yogurt, and cheese) as there is a potential for significant drug-food interaction. Additionally, patients taking cefixime should speak to their healthcare provider prior to using other medications (including antibiotics, antacids, sucralfate, iron, and calcium supplements), as there may be an increased risk for adverse reactions.

Interaction

Cefixime may interact with probenecid, certain antibiotics, anticoagulants, other drugs that weaken the immune system, and drugs used to treat gout. Additionally, cefixime can interact with other drugs in your system, such as certain antibiotics, anticoagulants, and other drugs that weaken the immune system. Therefore, it is important to tell your healthcare provider about any other medications you are taking prior to starting cefixime.

Disease Interaction

Patients with kidney impairment, or those with a history of allergic reactions to penicillins or cephalosporins, should not take cefixime. Patients with a previous history of seizures may require special precautions, as cefixime has been associated with seizures in some cases. Women who are pregnant or nursing should speak to their healthcare provider before taking cefixime.

Drug Interaction

Food Interactions

Patients taking cefixime should avoid taking large amounts of dairy products (including milk, yogurt, and cheese) as there is a potential for significant drug-food interaction.

Pregnancy Use

Cefixime is classified as a pregnancy Category B drug, which means that it is not expected to cause harm to a fetus unless the mother is taking a large dose close to the time of delivery. However, women who are pregnant or nursing should speak to their healthcare provider before taking cefixime.

Lactation Use

It is not known whether cefixime is secreted in breast milk. Therefore, women who are breastfeeding should speak to their healthcare provider before taking cefixime.

Acute Overdose

If an overdose of cefixime is suspected, contact your local poison control center or emergency room immediately. Symptoms of an overdose may include nausea, vomiting, stomach pain, and drowsiness.

Contraindication

Cefixime is contraindicated in patients with known hypersensitivity to cefixime or other cephalosporins. Additionally, cefixime is contraindicated in patients with a history of serious allergy or reaction to penicillin or cephalosporin antibiotics.

Use Direction

The dose of cefixime will be different for different patients. Follow the instructions given by your doctor. Cefixime is typically taken twice a day, 12 hours apart. Take your doses at least two hours before or after taking antacids, other antibiotics, iron, calcium, or zinc.Take the drug with a full glass of water or with food to reduce your risk of GI upset. Take the entire course of cefixime, even if your symptoms improve.

Storage Condition

Velofix Capsule 200 mg should be stored at room temperature in a tight, light-resistant container. Keep the container tightly closed when not in use. Store away from moisture, heat, and direct light.

Volume Of Distribution

Cefixime has an average volume of distribution of 0.47 L/kg. The volume of distribution is a measure of the amount of drug in the body. It is calculated by dividing the total amount of drug in the body by the amount of drug in the plasma.

Half Life

The average half-life of cefixime is 1 to 2 hours in adults and 2 to 4 hours in children. Half-life is the time it takes for the concentration or amount of drug in the body to be reduced by half. This will vary by patient and may differ slightly depending on age, gender, and other factors.

Clearance

The average clearance of cefixime is 0.46 L/h/kg. Clearance is the rate at which drug is cleared from the blood and is calculated by dividing the rate of drug elimination by the concentration of drug in the plasma.

Here you find in details version of Velofix Capsule 200 mg

Some Frequently Asked Questions About Velofix Capsule 200 mg

What is Velofix Capsule 200 mg?

Velofix Capsule 200 mg is an antibiotic medication which is used to treat infections caused by certain types of bacteria.

What can Velofix Capsule 200 mg be used to treat?

Velofix Capsule 200 mg can be used to treat a variety of bacterial infections including infections of the respiratory tract, urinary tract, skin, and some sexually transmitted diseases such as gonorrhea.

Who should not use Velofix Capsule 200 mg?

Velofix Capsule 200 mg should not be used by patients who are allergic to cephalosporin antibiotics or any of the ingredients in the medication. Patients with kidney or liver diseases should be monitored closely when taking this medication.

Is Velofix Capsule 200 mg safe for children?

Velofix Capsule 200 mg is generally considered safe for use in children, however it is important to discuss all the possible risks and benefits with your doctor before starting any medication.

What are the side effects of Velofix Capsule 200 mg?

The most common side effects of Velofix Capsule 200 mg are nausea, vomiting, stomach pain or discomfort, and diarrhea. Other side effects may include a headache, dizziness, and itching.

Are there any drug interactions with Velofix Capsule 200 mg?

Yes, Velofix Capsule 200 mg may interact with other medications, such as birth control pills, antacids, or probenecid. It is important to tell your doctor about any other medications that you are taking before starting Velofix Capsule 200 mg.

Is Velofix Capsule 200 mg available over the counter?

No, Velofix Capsule 200 mg is a prescription medication, and it is not available over the counter.

How often should I take Velofix Capsule 200 mg?

It is important to follow your doctor's instructions on how often to take Velofix Capsule 200 mg. Typically, this medication is taken once or twice daily for up to 10 days.

What should I do if I miss a dose of Velofix Capsule 200 mg?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the regular time.

What happens if I overdose on Velofix Capsule 200 mg?

If you think you have overdosed on Velofix Capsule 200 mg, it is important to seek medical attention immediately. Overdose symptoms may include nausea, vomiting, stomach pain, diarrhea, and fever.

Can I take Velofix Capsule 200 mg with food or milk?

Yes, it is generally recommended to take Velofix Capsule 200 mg with food or milk to reduce stomach upset.

Can I use Velofix Capsule 200 mg while pregnant?

The use of this medication during pregnancy should be discussed with your doctor. There is a potential risk of birth defects if Velofix Capsule 200 mg is used during the fetal stage of development.

Can I drink alcohol while taking Velofix Capsule 200 mg?

It is not recommended to drink alcohol while taking Velofix Capsule 200 mg as it can increase the risk of side effects.

Can Velofix Capsule 200 mg be used to treat a sinus infection?

Yes, Velofix Capsule 200 mg can be used to treat sinus infections, however this medication should only be used to treat bacterial infections, and it should not be used to treat viral infections.

Does Velofix Capsule 200 mg affect birth control?

Yes, Velofix Capsule 200 mg may affect the effectiveness of birth control pills, so it is important to use an alternate method of contraception, such as a condom, while taking this medication.

What forms does Velofix Capsule 200 mg come in?

Velofix Capsule 200 mg is available as tablets, capsules, and as a suspension.

Does Velofix Capsule 200 mg interact with any other medications?

Yes, Velofix Capsule 200 mg may interact with other medications such as antacids, probenecid, and birth control pills. It is important to tell your doctor about any other medications you are taking before starting Velofix Capsule 200 mg.

How quickly does Velofix Capsule 200 mg work?

Velofix Capsule 200 mg will usually start to work within 24 hours, however it may take several days for the full effects to be seen.

What should I do if I develop an allergic reaction to Velofix Capsule 200 mg?

If you develop any signs of an allergic reaction to Velofix Capsule 200 mg, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek medical attention immediately.

Can I take ibuprofen with Velofix Capsule 200 mg?

It is generally not recommended to take ibuprofen with Velofix Capsule 200 mg, as this combination may increase the risk of side effects. If you need to take ibuprofen, it is important to discuss this with your doctor before starting Velofix Capsule 200 mg.

Can I take Velofix Capsule 200 mg while breastfeeding?

Yes, Velofix Capsule 200 mg is generally considered safe for use while breastfeeding. However, it is important to discuss the possible risks and benefits with your doctor before starting this medication.

Is Velofix Capsule 200 mg safe for dogs?

Yes, Velofix Capsule 200 mg can be used in dogs to treat bacterial infections. It is important to follow your veterinarian’s instructions for dosage and treatment duration.

What should I avoid while taking Velofix Capsule 200 mg?

It is important to avoid drinking alcohol while taking Velofix Capsule 200 mg, as this can increase the risk of side effects. Also, this medication can make you more sensitive to the sun, so it is important to wear sunscreen and protective clothing when exposed to sunlight.

How long do I need to take Velofix Capsule 200 mg?

It is important to follow your doctor's instructions on how long to take Velofix Capsule 200 mg. Typically, this medication is taken for up to 10 days to treat bacterial infections.

Can I take Velofix Capsule 200 mg if I have a cold?

No, Velofix Capsule 200 mg is an antibiotic medication and should not be used to treat viral infections, including the common cold.

Are there any natural alternatives to Velofix Capsule 200 mg?

There are many natural alternatives to Velofix Capsule 200 mg that may be beneficial for the treatment of bacterial infections. These include garlic, honey, and probiotics, however it is important to discuss any natural alternatives with your doctor before starting any new treatment.

Will Velofix Capsule 200 mg cause diarrhea?

Yes, Velofix Capsule 200 mg may cause diarrhea, which is a common side effect of this medication.

Is Velofix Capsule 200 mg better than other antibiotics?

Velofix Capsule 200 mg may be better than other antibiotics for certain types of infections, however it is important to discuss the risks and benefits of different antibiotics with your doctor before starting any medication.

Can Velofix Capsule 200 mg be used to treat a bladder infection?

Yes, Velofix Capsule 200 mg can be used to treat bladder infections caused by certain types of bacteria.

Can I take Velofix Capsule 200 mg if I am allergic to penicillin?

Yes, Velofix Capsule 200 mg can be taken by patients who are allergic to penicillin, as it is in a different class of medications than penicillin.

Is Velofix Capsule 200 mg safe for seniors?

Yes, Velofix Capsule 200 mg is generally safe for seniors, however it is important to discuss any potential risks with your doctor before starting this medication.

Can Velofix Capsule 200 mg cause a yeast infection?

Yes, Velofix Capsule 200 mg can cause a yeast infection in some patients, due to an imbalance of bacteria in the body. This can usually be prevented by taking probiotics while taking Velofix Capsule 200 mg.

What is the generic name for Velofix Capsule 200 mg?

The generic name for Velofix Capsule 200 mg is cefixime.

Does Velofix Capsule 200 mg cause drowsiness?

Yes, Velofix Capsule 200 mg may cause drowsiness in some patients. It is important to use caution when driving or operating machinery while taking this medication.

Is Velofix Capsule 200 mg a type of penicillin?

No, Velofix Capsule 200 mg is not a type of penicillin. It is a cephalosporin antibiotic which belongs to a different class of medications than penicillin.

Can Velofix Capsule 200 mg be used to treat sinusitis?

Yes, Velofix Capsule 200 mg can be used to treat sinusitis caused by certain types of bacteria.

How is Velofix Capsule 200 mg taken?

Velofix Capsule 200 mg is taken by mouth in the form of tablets, capsules, or a suspension. It is important to follow your doctor's instructions on how to take this medication.

How long does it take for Velofix Capsule 200 mg to start working?

Velofix Capsule 200 mg will usually start to work within 24 hours, however it may take several days for the full effects to be seen.

Does Velofix Capsule 200 mg treat bacterial infections?

Yes, Velofix Capsule 200 mg is an antibiotic medication which is used to treat infections caused by certain types of bacteria.

Does Velofix Capsule 200 mg interact with warfarin?

Yes, Velofix Capsule 200 mg may interact with warfarin and increase the risk of bleeding. It is important to discuss possible drug interactions with your doctor before taking this medication.

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