Valto P

Valto P Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Valto P is a brand name. Its generic name is Parecoxib.

Introduction

Valto P is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with osteoarthritis and rheumatoid arthritis. It is typically prescribed in combination with other medications for treating osteoarthritis and rheumatoid arthritis.

Uses

Valto P is used to treat pain and inflammation associated with osteoarthritis and rheumatoid arthritis. It is typically prescribed in combination with other medications for treating osteoarthritis and rheumatoid arthritis.

Mechanism of Action

Valto P works by blocking the enzyme cyclooxygenase-2 (COX2), which is responsible for producing prostaglandins (chemicals that cause pain and inflammation). This explains its anti-inflammatory effects.

How Long Does it Take to Work

Valto P typically takes 1 to 2 hours to start working and its effects can last up to 8 hours.

Absorption

Valto P is rapidly and completely absorbed after oral administration.

Route of Elimination

Valto P is eliminated primarily in the urine, with renal clearance accounting for about 70% of the dose. The remainder is metabolized in the liver.

Dosage

The usual dose of Valto P for adults is 40 mg, taken twice a day. Your doctor may prescribe you a lower dose if you have kidney or heart-related conditions.

Administration

Valto P should be taken orally with a full glass of water.

Side Effects

Common side effects of Valto P include nausea, diarrhea, headaches, dizziness, rash, gas, and upset stomach.

Toxicity

Valto P is generally safe and well tolerated when used at recommended doses. However, taking higher doses or long-term use of Valto P increases the risk of serious side effects such as heart attack, stroke, and intestinal bleeding.

Precautions

Patients taking Valto P should avoid alcohol consumption and smoking. You should also inform your doctor if you have any heart, liver, or kidney problems before taking Valto P.

Interactions

Valto P can interact with other drugs, such as warfarin, ACE inhibitors, methotrexate, and diuretics. You should always inform your doctor about any medications you are taking before starting Valto P.

Disease Interactions

Valto P should be used with caution in patients with a history of heart disease, stroke, or bleeding disorders. Valto P may also increase the risk of fluid retention or edema in patients with kidney or liver diseases.

Drug Interactions

Valto P may interact with other drugs such as warfarin, ACE inhibitors, methotrexate, and diuretics. You should always inform your doctor about any medications you are taking before starting Valto P.

Food Interactions

Taking Valto P with certain foods may decrease its absorption. It is important to take Valto P on an empty stomach or at least two hours after a meal.

Pregnancy Use

Valto P is not recommended for use in pregnant women. It may cause harm to the unborn baby.

Lactation Use

It is not known whether Valto P is excreted in human milk. Therefore, it is not recommended for use in breastfeeding women.

Acute Overdose

An overdose of Valto P can cause symptoms such as nausea, vomiting, stomach pain, and diarrhea. If an overdose is suspected, seek immediate medical attention.

Contraindication

Valto P is contraindicated in patients with a known allergy to this medication, as well as in patients with severe bleeding disorders, severe liver or kidney impairment, or recent history of stroke or heart attack.

Use Direction

Valto P should be used as directed by your physician. Your doctor may adjust the dosage as needed based on your weight, severity of your condition, and other medical conditions you may have.

Storage Condition

Valto P should be stored at room temperature, protected from light and moisture.

Volume of Distribution

The volume of distribution of Valto P is 84 L, meaning that the drug distributes well throughout the body's tissues.

Half Life

Valto P has a half-life of approximately 7 hours.

Clearance

The clearance of Valto P is mainly by the kidney, with renal clearance accounting for about 70% of the dose. The remainder is metabolized in the liver.

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