Urivel

Urivel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Urivel is a brand name. Its generic name is Flavoxate.

Urivel

Urivel is a synthetic compound used to relax the smooth muscle of the urinary bladder, enabling it to hold more urine and thus aiding relief of urinary frequency and urgency caused by bladder inflammation (cystitis). It also helps to reduce the sense of urgency and the amount of urine leakage.

Uses for Urivel

Urivel is primarily indicated for the treatment of bladder spasms, irritative bladder symptoms such as urinary frequency and discomfort, urgency, and nocturia, as well as for the treatment or prevention of dysuria following cystoscopy or radiation cystitis.

Mechanism of Action

Urivel causes relaxation of smooth muscle and exhibits anticholinergic activity by blocking the muscarinic action of acetylcholine, mainly on the bladder musculature. This reduces frequency of contracting detrusor and reduces smooth muscle spasms in overactive bladder (OAB).

How Long Does it Take to Work?

Urivel takes effect within one hour of ingestion, with the greatest improvement in symptoms at four hours, and symptom relief is usually maintained up to 24 to 48 hours.

Absorption

Urivel is rapidly absorbed from the gastrointestinal tract with an onset of action at 1 hour after oral administration. Peak plasma levels occur within 2 – 3 hours with a bioavailability of 73%. It is well distributed in the body, with an apparent volume of distribution of 0.46 L/kg.

Route of Elimination

Urivel is metabolized by the liver and mostly eliminated in the urine as inactive metabolites. The elimination half-life is 4 – 6 hours.

Dosage

The recommended starting dose of flavoxate is 100 mg three times a day, administered orally. Depending on individual response and symptom control, the dose can be increased to 200 mg three times a day. The maximum recommended daily dose is 600mg.

Administration

Urivel should be taken orally with a glass of water. It can be taken with or without food, but taking with food may help to reduce digestive side effects.

Side Effects

The most commonly reported side effects of flavoxate include dry mouth, nausea, constipation, dizziness, and drowsiness. Discontinue use and seek medical attention if any serious side effects occur, such as difficulty breathing or a rash.

Toxicity

In a study conducted in rats, the oral LD50 of flavoxate was >5000 mg/kg. No clinical cases of toxicity were reported.

Precautions

• Urivel should be used with caution in patients with impaired renal, cardiovascular, or hepatic function, or in those with urinary obstruction.
• It should not be used in combination with other drugs that impair urination.
• It should not be used in patients with hypersensitivity to flavoxate.

Interactions

Urivel may interact with other drugs, including antibiotics, antispasmodics, antihypertensives, diuretics, and other medications used to treat overactive bladder. It is important to check with your doctor before starting any new medications.

Disease Interactions

• Urivel should not be used in patients with glaucoma, ulcerative colitis, myasthenia gravis, bladder outflow obstruction, or intestinal obstruction.
• It may worsen symptoms if taken in patients with prostatic hyperplasia or bladder neck obstruction.

Drug Interactions

• Urivel may increase the absorption and effects of other drugs, such as carbamazepine, warfarin, and digitalis glycosides.
• It may decrease the effects of anticholinergic drugs, such as oxybutynin and tolterodine.
• It may also interact with other drugs used to treat symptoms of overactive bladder, such as darifenacin, solifenacin, and fesoterodine.

Food Interactions

No food-related interactions are known to occur with flavoxate.

Pregnancy Use

Urivel is listed as a Pregnancy Category B medication, which means animal studies have revealed no evidence of harmful effects to the fetus, but there are no controlled studies available in pregnant women. Urivel should only be used if the potential benefit outweighs the potential risks.

Lactation Use

It is unknown if flavoxate is secreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, women should not use flavoxate while nursing.

Acute Overdose

In the event of an acute overdose of flavoxate, symptomatic and supportive measures should be provided. Gastric lavage or emesis may be beneficial if performed within 1 hour of ingestion.

Contraindication

Urivel is contraindi

Here you find in details version of Urivel

Some Frequently Asked Questions About Urivel

What is Urivel?

Urivel is a prescription medication used to reduce muscle spasms caused by medical problems such as bladder or intestinal disorders or neurological disorders.

How does Urivel work?

Urivel works by inhibiting acetylcholine receptors, which help regulate involuntary muscle movement. This prevents spasms in the affected area and relieves symptoms.

What are the side effects of Urivel?

The most common side effects of Urivel are dry mouth, dizziness, headache, nausea, and constipation. Talk to your doctor if you experience any side effects while taking Urivel.

Who should not take Urivel?

You should not take Urivel if you are allergic to flavoxate or any other components of the medication. You should also not take Urivel if you have a history of urinary retention, obstructive or paralytic urological conditions, or myasthenia gravis.

Can Urivel be used in elderly patients?

Yes, Urivel can be used in elderly patients. However, elderly patients are generally more sensitive to its side effects than younger patients, so they should be monitored closely for any adverse effects.

Is Urivel a habit forming drug?

No, Urivel is not a habit forming drug. It does not produce the same euphoria associated with habit-forming drugs, so it is not addictive.

What is the usual dosage of Urivel?

The usual starting dosage for flavoxate is one 200-mg tablet two to three times a day. Your doctor may adjust your dosage based on your response to the medication and your medical condition.

Should Urivel be taken on an empty stomach?

No, Urivel should not be taken on an empty stomach. It is best taken with food or a full glass of water at least 30 minutes before or 2 hours after a meal.

Can Urivel be taken with other medications?

Yes, Urivel can be taken with other medications. However, you should always talk to your doctor before taking any other medications alongside Urivel, as certain drugs may interact with it in a negative way.

Is Urivel available over the counter?

No, Urivel is not available over the counter. It is a prescription medication and must be obtained from a doctor.

Can Urivel be used to treat urinary incontinence?

No, Urivel is not indicated to treat urinary incontinence and should not be used for that purpose.

Can Urivel be taken with alcohol?

No, it is not recommended that Urivel be taken with alcohol as it may increase the risk of certain side effects.

Can Urivel cause drowsiness?

Yes, Urivel can cause drowsiness or dizziness in some people. You should not drive or operate heavy machinery until you know how Urivel affects you.

Are there any long term side effects of taking Urivel?

No, there are no known long term side effects associated with taking Urivel. However, as with any medication, you should talk to your doctor if any side effects persist or worsen.

Can Urivel be used to treat bladder spasms?

Yes, Urivel has been approved for the treatment of bladder spasms. It works by inhibiting acetylcholine receptors, which help regulate involuntary muscle movement and can help relieve symptoms associated with bladder spasms.

Can Urivel be used to treat overactive bladder?

While Urivel is not specifically approved to treat overactive bladder, it may be prescribed off-label by your doctor if they believe it would help manage your symptoms. Talk to your doctor about the best course of treatment for you.

What happens if I miss a dose of Urivel?

If you miss a dose of Urivel, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next one as scheduled. Do not take an extra dose to make up for the missed dose.

Can Urivel be used in children?

Urivel has not been approved for use in children, so it is not recommended. If your child is experiencing bladder or intestinal disorders or neurological disorders, talk to your doctor about the best course of treatment.

Is Urivel safe for pregnant women?

No, Urivel is not recommended for use in pregnant women. Talk to your doctor about the best course of treatment for you if you are pregnant.

What should I do if I experience an allergic reaction to Urivel?

If you experience an allergic reaction such as hives, swelling of the face, lips, or tongue, difficulty breathing, or itching, stop taking Urivel immediately and seek medical attention.

Can Urivel cause weight gain?

No, Urivel has not been known to cause weight gain in people taking it as prescribed. However, if you experience any unusual changes in weight while taking Urivel, it is important to speak to your doctor.

What should I do if I experience dry mouth while taking Urivel?

If you experience dry mouth while taking Urivel, you can chew sugar-free gum or suck on sugar-free hard candy to help stimulate saliva production. You should also drink plenty of water throughout the day.

What are the most common side effects of Urivel?

The most common side effects of Urivel are dry mouth, dizziness, headache, nausea, and constipation. If any of these side effects become severe or do not go away, talk to your doctor.

Can Urivel interact with other medications?

Yes, Urivel can interact with certain medications, such as antacids, certain antibiotics, and certain antifungals. It is important to tell your doctor about any other medications you may be taking before starting Urivel.

Should Urivel be taken at the same time each day?

It is not necessary to take Urivel at the same time each day, but it is important to take it regularly in order to maintain an effective level in your blood. Talk to your doctor about the best way to take your medication.

Can Urivel be split in half?

Yes, Urivel tablets can be cut or split in half. However, you should always take the entire dose as prescribed by your doctor to ensure the medication is working correctly.

Can Urivel be taken with other OTC medications?

Yes, Urivel can be taken with other OTC medications as long as they do not interact with each other. It is important to talk to your doctor or pharmacist before taking any other medications, including OTC medications, while taking Urivel.

Can Urivel be taken with other supplements?

Yes, Urivel can be taken with other dietary supplements as long as they do not interact with each other. Always talk to your doctor or pharmacist before taking any other supplements while taking Urivel.

What are the long-term effects of taking Urivel?

There are no known long-term side effects associated with taking Urivel. However, as with any medication, you should talk to your doctor if any side effects persist or worsen.

Can Urivel cause muscle spasms?

No, Urivel does not cause muscle spasms. In fact, it works by inhibiting acetylcholine receptors, which can help reduce muscle spasms.

Can Urivel be taken with food?

Yes, Urivel can be taken with food or a full glass of water at least 30 minutes before or 2 hours after a meal. However, you should always talk to your doctor about the best way to take your medication.

Can Urivel be taken if I have glaucoma?

Yes, it is generally safe to take Urivel if you have glaucoma. However, you should always talk to your doctor before starting any medication, including Urivel, to make sure it is safe for you.

Can Urivel be used to treat pain?

No, Urivel is not indicated for the treatment of pain and should not be used for that purpose.

Can Urivel be taken for more than 3 days?

Yes, Urivel can be taken for more than 3 days if it is prescribed by your doctor. However, the length of treatment should be determined by your doctor based on the severity of your condition and your response to treatment.

Can Urivel cause liver damage?

No, it is not known to cause liver damage. However, you should always talk to your doctor if you have any concerns about your liver while taking Urivel.

Will Urivel affect my ability to drive or operate heavy machinery?

Yes, Urivel can cause drowsiness or dizziness in some people. You should not drive or operate heavy machinery until you know how Urivel affects you.

Can Urivel cause kidney problems?

No, Urivel has not been known to cause kidney problems. However, if you have existing kidney problems, talk to your doctor before taking Urivel.

What should I do if I experience stomach upset while taking Urivel?

If you experience stomach upset while taking Urivel, try taking it with food or a full glass of water. You should also speak to your doctor if the stomach upset persists or worsens.

Will Urivel interact with other OTC medications or supplements?

Yes, Urivel may interact with certain OTC medications or supplements. Always talk to your doctor or pharmacist before taking any other medications, including OTC medications, while taking Urivel.

Can Urivel cause anxiety?

No, Urivel has not been known to cause anxiety in people taking it as prescribed. However, if you experience any signs of anxiety while taking Urivel, it is important to speak to your doctor.

What If I take too much Urivel?

If you accidentally take too much Urivel, you should seek medical help immediately. Overdose symptoms may include nausea, vomiting, stomach pain, or difficulty breathing.