Terramycin
Terramycin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Terramycin is a brand name. Its generic name is Oxytetracycline.
Terramycin
Terramycin is an antibiotic used to treat a wide variety of bacterial infections, including respiratory infections, skin infections, chlamydia, and Lyme disease. It belongs to a class of drugs known as tetracyclines. Terramycin works by inhibiting protein synthesis, thereby preventing bacteria from producing the proteins they need to grow and proliferate.
Uses for
Terramycin is primarily used to treat bacterial infections, such as: respiratory infections, including bronchitis, tonsillitis, and pneumonia; skin infections, including acne, impetigo, and rosacea; gastrointestinal infections, including traveler’s diarrhea; and sexually-transmitted infections, including chlamydia and Lyme disease.
Mechanism of Action
Terramycin works by binding to the bacterial ribosome, preventing bacterial protein synthesis and thereby inhibiting bacterial growth. This stops the bacteria from multiplying and strengthens the body's natural defense mechanisms to fight infection.
How Long Does It Take to Work?
When taken as directed, oxytetracycline can take effect in as little as one hour. Depending on the severity of the infection and other factors, some people may experience relief of symptoms in as little as one day. However, for the most effective results, it is important to complete the full course of treatment as directed by your doctor.
Absorption
Terramycin is rapidly absorbed when taken orally, with peak concentrations occurring in about two hours. It is also available in intravenous form.
Route of Elimination
Terramycin is excreted in urine and feces.
Dosage
Terramycin dosage will vary depending on the type of infection being treated. For most infections, the typical adult dose is between 250 to 500 mg taken every twelve hours. Terramycin may also be prescribed as an intravenous infusion, usually at a rate of 200 mg/day for up to 10 days.
Administration
Terramycin can be taken orally in capsule or tablet form, or it can be injected intravenously. It should be taken with plenty of fluids to help ensure that it can be absorbed properly.
Side Effects
The most common side effects of oxytetracycline include nausea, vomiting, diarrhea, and abdominal pain. Other side effects may include headache, dizziness, skin rash, itching, hives, difficulty breathing or swallowing, and joint pain. In some cases, oxytetracycline may cause the bacteria it is intended to treat to become resistant to treatment. If you experience any of these side effects, contact your doctor immediately.
Toxicity
Overdose of oxytetracycline may cause irreversible damage to the kidneys and other organs. In cases of suspected overdose, immediate medical attention should be sought.
Precautions
Terramycin should be used with caution in people with kidney or liver disease, and in those taking anticoagulants or certain antibiotics. It should also be used with caution in pregnant and nursing women, as it can have adverse effects on developing fetus or newborn child.
Interaction
Terramycin may interact with other medications, including anticoagulants, other antibiotics, nonsteroidal anti-inflammatory drugs, and antacids. It is important to tell your doctor about all medications you are taking when being prescribed oxytetracycline.
Disease Interaction
Terramycin may interact with certain infectious diseases. For example, patients with tuberculosis may be more susceptible to side effects. In addition, patients with AIDS may have an increased risk of an allergic reaction.
Drug Interaction
Terramycin may interact with other drugs, including anticoagulants, nonsteroidal anti-inflammatory drugs, and certain antibiotics. It is important to tell your doctor about all drugs, supplements, and herbal products you are taking when being prescribed oxytetracycline.
Food Interactions
Certain foods can interfere with the absorption of oxytetracycline. They include milk, dairy products, and antacids. It is important to tell your doctor if you are taking any food or supplement that could interact with metronidazole.
Pregnancy Use
Terramycin should be used with caution during pregnancy. While it is generally considered safe to use in the first trimester, it has been associated with birth defects in the second and third trimesters. Discuss all risks with your doctor.
Lactation Use
Terramycin is excreted in breast milk and may cause side effects in the baby, such as diarrhea and irritation. It should be used with caution during lactation, and only when specifically recommended by your doctor.
Acute Overdose
Acute, large-scale overdoses of oxytetracycline can cause symptoms such as nausea, vomiting, diarrhea, abdominal pain, dizziness, and confusion. Hyperactivity, muscle weakness, and convulsions may also occur. It is important to seek medical attention immediately if you suspect an overdose.
Contraindication
Terramycin is contraindicated in patients with known hypersensitivity (allergy) to tetracycline antibiotics. It is also contraindicated in patients who are pregnant or lactating.
Use Direction
Terramycin should be taken as directed by your doctor. Depending on the severity of the infection, it is typically prescribed as 250-500 mg every 12 hours. It should be taken with plenty of fluids and not taken on an empty stomach.
Storage Condition
Terramycin should be stored at room temperature in a dry place. It should be kept away from light, heat, and moisture.
Volume of Distribution
Terramycin has a volume of distribution of 1.38 L/kg.
Half Life
Terramycin has an elimination half-life of two to three hours.
Clearance
Terramycin has an apparent clearance of 0.24 L/h/kg.
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Some Frequently Asked Questions About Terramycin
What is Terramycin?
Terramycin is an antibiotic that is used to treat a variety of bacterial infections. It is an effective drug against a wide range of bacteria, including those that cause acne, gonorrhea, and chlamydia.
What is the dosage of Terramycin?
The dosage of Terramycin depends on the type and severity of the infection being treated. Generally, it is recommended that adults take 250-500mg four times daily and children take 25-50mg/kg of body weight in four divided doses every six hours.
What are the possible side-effects of Terramycin?
The common side effects of Terramycin include nausea, vomiting, and abdominal pain. In rare cases, more serious side effects such as lupus, pancreatitis, and allergic reactions may occur. Contact your doctor immediately if you experience any of these side effects.
How long does it take for Terramycin to work?
The exact time for Terramycin to take effect varies depending on the type and severity of the infection. Generally, it takes 1-2 days to show some improvement in the symptoms, and it may take longer to completely cure the infection.
Is Terramycin safe to use during pregnancy?
Terramycin should be used with caution during pregnancy. The possible risks associated with the use of this antibiotic should be discussed with your doctor before considering its use during pregnancy.
Can I drink alcohol while taking Terramycin?
It is not recommended to consume alcohol while taking Terramycin, as it can reduce the effectiveness of the antibiotic and increase the risk of side effects.
What should I do if I miss a dose of Terramycin?
If you miss a dose of Terramycin, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take the next one as scheduled.
Is Terramycin effective against Staphylococcus aureus infections?
Terramycin is an effective antibiotic for treating Staphylococcus aureus infections.
Is Terramycin safe for children?
Terramycin is generally safe for children provided that the correct dosage is administered. Discuss the use of Terramycin with your doctor before giving it to a child.
Can I take Terramycin with other medications?
Yes, you can take Terramycin with other medications. However, it is important to check with your doctor or pharmacist to determine if there are any interactions between medications.
Can I buy Terramycin over-the-counter?
No, Terramycin is prescription-only medication, meaning it cannot be purchased without a prescription.
What should I do if I overdose on Terramycin?
If you or someone else has taken an overdose of Terramycin, seek medical attention immediately. The effects of an overdose can be severe and even life-threatening.
Can Terramycin cause thrush?
Yes, Terramycin can cause thrush, a fungal infection of the mouth. If you experience white patches in your mouth or throat, contact your doctor as soon as possible.
What other infections does Terramycin treat?
Terramycin is effective in treating a wide variety of bacterial infections, including urinary tract infections, skin infections, and anaerobic bacterial infections.
What is the usual duration of treatment with Terramycin?
The usual duration of treatment with Terramycin is 10 days to 4 weeks, depending on the severity of the infection being treated.
Is it safe to use Terramycin for long periods?
Using Terramycin for long periods can be dangerous and can increase the risk of side effects. Consult your doctor if you need to use Terramycin for a prolonged period of time.
Can I take paracetamol with Terramycin?
Yes, paracetamol can be taken with Terramycin. However, it is important to check with your doctor or pharmacist regarding any potential drug interactions.
Can Terramycin be used to treat urinary tract infections?
Yes, Terramycin can be used to treat urinary tract infections.
How do I store Terramycin?
Store Terramycin at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets.
Can Terramycin cause dizziness?
Yes, Terramycin can cause dizziness or lightheadedness as a side effect. If you experience dizziness, contact your doctor immediately.
What if I accidentally take an extra dose of Terramycin?
If you accidentally take an extra dose of Terramycin, contact your doctor or pharmacist for advice.
Can Terramycin be used to treat strep throat?
Yes, Terramycin can be used to treat strep throat.
Do I need to take Terramycin with food?
Yes, Terramycin should be taken with food or a glass of milk to reduce the risk of stomach upset.
What precautions should I take when taking Terramycin?
Take all of your medication as prescribed, and don't stop taking it without consulting your doctor. Drink plenty of fluids while taking this medication, and don't consume alcohol. Wear protective clothing, such as long-sleeved shirts and hats, when outdoors, as this medication can make your skin become more sensitive to the sun.
What is the difference between Terramycin and tetracycline?
Terramycin is an extended-release form of tetracycline, meaning that it is released slowly into the body over a longer period of time. The extended-release form of Terramycin requires fewer daily doses than the standard tetracycline.
Can I take antihistamines while taking Terramycin?
Yes, it is generally safe to take antihistamines while taking Terramycin. However, some antihistamines may interact with Terramycin, so it is important to check with your doctor or pharmacist before taking both medications together.
Is Terramycin a penicillin?
No, Terramycin is not a penicillin. Terramycin is a tetracycline antibiotic.
Can I take other medications at the same time as Terramycin?
It is possible to take other medications at the same time as Terramycin, however, it is important to check with your doctor or pharmacist before doing so, as some medications may interact with Terramycin.
What are the signs of an allergic reaction to Terramycin?
Signs of an allergic reaction to Terramycin may include wheezing, rash, hives, itching, swelling of the face, lips, tongue, or throat, dizziness, or difficulty breathing.
Can I take other antibiotics with Terramycin?
No, it is not recommended to take other antibiotics at the same time as Terramycin, as this may reduce the effectiveness of the antibiotic and increase the risk of side effects.
Should Terramycin be taken with or without food?
Terramycin should generally be taken with food or a glass of milk to reduce the risk of stomach upset.
Can Terramycin be taken long-term?
Using Terramycin long-term is not recommended as it can be dangerous and can increase the risk of side effects. Consult your doctor if you need to use Terramycin for a prolonged period of time.
Can I take ibuprofen while taking Terramycin?
Yes, ibuprofen can usually be taken while taking Terramycin. However, it is important to check with your doctor or pharmacist regarding any potential drug interactions.