Targit

Targit Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Targit is a brand name. Its generic name is Telmisartan.

Introduction

Targit is a medication that belongs to the angiotensin-II receptor blocker (ARB) class. It is used to treat high blood pressure (hypertension), heart failure, and other related disorders.

Uses

Targit is used to treat hypertension and heart failure. It is also indicated for the prevention of cardiovascular morbidity in high-risk patients, and for reducing the risk of stroke and other major cardiovascular events. It can also be used to prevent kidney damage in diabetic patients.

Mechanism of Action

Targit works by blocking the actions of angiotensin-II (a protein that causes blood vessels to constrict) and thereby widening the blood vessels so that the pressure of the blood is reduced.

How Long Does it Take to Work?

Generally, the effects of telmisartan can be seen within 2 weeks of starting the medication. However, it may take up to 4 weeks of regular use for the effects of the medication to become fully evident.

Absorption

Targit is well absorbed from the gastrointestinal tract with peak plasma concentrations being achieved in 3-4 hours after an oral dose.

Route of Elimination

The majority of the telmisartan is eliminated unchanged in the urine, via active tubular secretion.

Dosage

The recommended dose of telmisartan is 20-80 mg orally once per day. The dose should be adjusted based on the patient's response and should not exceed 80 mg once daily.

Administration

Targit should be taken orally with food or a glass of water, once daily. It is not recommended to crush, chew or split the tablets.

Side Effects

Common side effects of telmisartan include dizziness, headache, fatigue, diarrhea, stomach pain, and increased urination. Less common but serious side effects include liver damage, fainting, and elevated blood sugar levels.

Toxicity

Targit is relatively safe and well-tolerated. Overdose of telmisartan may cause hypotension (low blood pressure), hyperkalemia (high potassium levels in the blood), and bradycardia (slow heart rate).

Precaution

Patients should inform their doctor about any medical history, the use of any other prescription or over-the-counter medications, as well as supplements and vitamins prior to taking telmisartan. Targit should be used with caution in pregnant or breastfeeding women.

Interaction

Targit may interact with other medications such as potassium-sparing diuretics, potassium supplements, angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interaction

Patients with diabetes, hypertension, congestive heart failure, liver disease, or kidney disease should use telmisartan with caution and be monitored more closely by a doctor.

Drug Interaction

Use of telmisartan with certain drugs, including angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and potassium-sparing agents may increase the risk of adverse effects.

Food Interactions

Targit should be taken with food for optimal absorption.

Pregnancy Use

Targit should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation Use

Targit is not recommended for use in breastfeeding mothers as it is excreted in breast milk and may cause adverse reactions in the infant.

Acute Overdose

If an overdose of telmisartan is suspected, the patient should be monitored for symptoms of hypotension and hypovolemia (low blood volume). Treatment of overdose involves supportive care, which may include intravenous fluids, sympatomimetic agents (such as epinephrine), and diuretics.

Contraindication

Targit is contraindicated in patients with hypersensitivity to any of the ingredients of the medication, severe hepatic impairment, and in patients with biliary cirrhosis.

Use Direction

Targit should be used as directed by the doctor. It is generally recommended to take the dose in the morning to avoid it interfering with sleep.

Storage Condition

Targit should be stored at room temperature, between 15°C and 30°C. Keep medication away from light, moisture, and heat. Store out of reach of children and pets.

Volume of Distribution

Targit has a volume of distribution of 11L/kg.

Half Life

The elimination half-life of telmisartan is 24 hours.

Clearance

The oral clearance of telmisartan is 1.3 L/hour/kg.

Here you find in details version of Targit

Some Frequently Asked Questions About Targit

What is Targit?

Targit is a type of medication used to treat high blood pressure (hypertension) and heart failure. It is known as an angiotensin II receptor blocker, which works by blocking the hormone angiotensin so as to widen blood vessels, helping to reduce blood pressure and improve the flow of blood around the body.

What are the benefits of Targit?

Targit is used to treat high blood pressure (hypertension) and heart failure. It can also help reduce the risk of stroke, heart attack, and cardiac death in patients who have already had cardiovascular events. It is also used to decrease the risk of kidney failure due to diabetes, as well as to reduce stress and fatigue.

How does Targit work?

Targit works by blocking the action of the hormone angiotensin II, which is involved in narrowing of blood vessels. This helps to widen blood vessels, reducing blood pressure and improving the flow of blood around the body.

How long does it take for Targit to work?

It usually takes 4-6 weeks for Targit to start working. The full effect on blood pressure may not be seen for up to 8 weeks after starting treatment.

Is Targit safe?

Targit is generally well tolerated and considered safe for use by most patients, however it should not be taken if you are pregnant, have an allergy to angiotensin II receptor blockers, or have persistent liver problems. Always speak to your doctor before taking any medication.

Who should not take Targit?

Targit should not be taken by pregnant women, those with an allergy to angiotensin II receptor blockers, and those with persistent liver problems. It should also not be taken during breastfeeding.

What are the side effects of Targit?

The most common side effects of Targit are headache, dizziness, and fatigue. Other side effects include nausea, diarrhea, and rash. If any of these side effects become severe, contact your doctor.

What happens if I miss a dose of Targit?

If you miss a dose of Targit, take it as soon as you remember. However, if it is close to the time for your next dose, then skip it and take the next dose as normal. Do not take a double dose to make up for a missed one.

What should I avoid while taking Targit?

Avoid drinking alcohol while taking Targit, as it can increase the risk of side effects. Also, avoid taking other medications or supplements which might interact with Targit. Ask your doctor for a list of medications or supplements to avoid, as some can increase the risk of side effects.

Can I drive or operate heavy machinery while taking Targit?

It is generally safe to drive or operate heavy machinery while taking Targit. However, always speak to your doctor if you experience any dizziness or fatigue while taking this medication, as it could affect your ability to concentrate or react quickly.

What happens if I overdose on Targit?

If you overdose on Targit, seek emergency medical attention. Overdose symptoms may include a rapid heartbeat, difficulty breathing, muscle weakness, light-headedness, and dizziness.

Does Targit interact with any other medications?

Yes, Targit may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics, and certain heart medications. Always tell your doctor about any medications you are taking before starting Targit.

What should I tell my doctor before taking Targit?

Before taking Targit, you should tell your doctor about any existing medical conditions or allergies you have, as well as any medications you are currently taking. This will help to avoid any potential side effects or interactions.

Is there a generic version of Targit available?

Yes, some generic versions of Targit are available. Make sure to speak to your doctor or pharmacist to see if this would be a suitable option for you.

Is Targit available over-the-counter?

No, Targit is only available with a prescription. You will need to talk to your doctor about whether Targit is the right choice for you.

How long do I need to take Targit?

The duration of Targit treatment will depend on why you are taking it, as well as your individual circumstances. Your doctor will be able to advise you on an appropriate course of treatment.

Is Targit safe for long-term use?

Yes, Targit is generally safe for long-term use, but always speak to your doctor about any potential risks. It is also important to be regularly monitored while taking this medication.

Can Targit be taken with other medications?

Yes, Targit can be taken with other medications. However, it is important to talk to your doctor before taking any additional medications, as some may interact with Targit in a harmful way.

Is Targit safe during pregnancy?

No, Targit is not safe during pregnancy and should not be taken by pregnant women. Talk to your doctor about other treatments which may be suitable.

Can I take nonsteroidal anti-inflammatory drugs (NSAIDs) while taking Targit?

No, NSAIDs should not be taken while taking Targit, as they can interact in a harmful way and increase the risk of side effects. Talk to your doctor or pharmacist about other medications which may be suitable.

Can I take Targit if I have kidney problems?

Yes, it is generally safe to take Targit if you have kidney problems. However, always speak to your doctor about potential risks before taking this medication.

Can Targit cause erectile dysfunction?

Targit could potentially cause erectile dysfunction. Contact your doctor if you experience any issues related to your sexual health while taking this medication.

Can Targit cause weight gain?

Targit could potentially cause weight gain in some cases. Consult your doctor if you are concerned about weight gain while taking this medication.

Could Targit cause hair loss?

It is unlikely that Targit would cause hair loss. However, if you notice any changes in your hair while taking Targit, consult your doctor.

Does Targit affect potassium levels?

Targit has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.

Can Targit make me sleepy?

Yes, Targit can cause fatigue and dizziness. If this occurs, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.

Can I take ibuprofen while taking Targit?

No, ibuprofen should not be taken while taking Targit, as it can interact in a harmful way and increase your risk of side effects. Talk to your doctor about other pain relief options.

Is Targit a diuretic?

No, Targit is not a diuretic. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.

Does Targit cause coughing?

Targit could potentially cause coughing in some cases. If you experience coughing while taking this medication, contact your doctor.

Can Targit cause dizziness?

Yes, Targit can cause dizziness in some cases. If you experience dizziness, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.

Can Targit cause muscle pain?

Yes, Targit could potentially cause muscle pain in some cases. If you experience muscle pain or any other side effects while taking this medication, contact your doctor.

Is Targit a Beta-blocker?

No, Targit is not a Beta-blocker. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.

Can Targit cause high potassium levels?

Yes, Targit has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.

Does Targit need to be taken with food?

No, Targit does not need to be taken with food. However, it is important to take it at the same time each day to maintain a consistent level in your bloodstream.

Can Targit cause bloating?

Yes, Targit could potentially cause bloating in some cases. If you experience bloating while taking this medication, contact your doctor.

Should I take Targit if I have diabetes?

Yes, Targit can be taken if you have diabetes. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.

Can I take Targit if I have asthma?

Yes, Targit can be taken if you have asthma. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.

Can Targit cause a sore throat?

Targit could potentially cause a sore throat in some cases. If you experience a sore throat while taking this medication, contact your doctor.

Can Targit cause dehydration?

Yes, Targit could potentially cause dehydration in some cases. If you experience any symptoms of dehydration while taking this medication, contact your doctor.

Is Targit generic or brand name?

Targit is the brand name for the medication. Some generic versions of Targit are available, however always speak to your doctor or pharmacist before taking any generic medications.

Is Targit water soluble?

Yes, Targit is water soluble. This means that it can be absorbed into the bloodstream quickly.