Tanin

Tanin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tanin is a brand name. Its generic name is Tizanidine.

Tanin Introduction

Tanin is a short-acting muscle relaxant used to treat spasticity, including muscle spasms, pain, and stiffness caused by neurological disorders such as cerebral palsy, multiple sclerosis, and spinal cord injuries. It is usually taken orally, but can also be injected into a muscle.

Uses For

Tanin is used to treat spasticity resulting from diseases such as multiple sclerosis, spinal cord injuries, cerebral palsy, and stroke. It can also be used to relieve muscle spasms and pain.

Mechanism of Action

Tanin works by blocking nerve signals from reaching the brain, thereby reducing the intensity of muscle spasms. It also relaxes muscles which can reduce pain and stiffness.

How Long Does it Take to Work?

Tanin typically takes effect within 30 to 60 minutes after it is consumed. It is a short-acting medication, so the effects will usually last 8-9 hours.

Absorption

Tanin is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached in 1-2 hours.

Route of Elimination

Tanin is mainly eliminated by the kidneys. Approximately 20% is excreted unchanged in the urine.

Dosage

The recommended adult dose of tizanidine is 2-4 mg orally every 6-8 hours, not to exceed 36 mg in a 24 hour period. Maximum benefits may not be seen for up to 2-3 weeks. The maximum recommended daily dose is 36 mg.

Administration

Tanin should be taken with food or immediately after eating. Do not take tizanidine with other drugs that cause drowsiness or decrease alertness. Examples of these drugs include tricyclic antidepressants, other muscle relaxants, pain relievers, sleeping pills, and tranquilizers.

Side Effects

Common side effects of tizanidine include dry mouth, drowsiness, dizziness, lightheadedness, headache, constipation, nausea, and weakness. More serious side effects may include low blood pressure, slowed breathing, and changes in mental status.

Toxicity

Tanin may cause significant toxicity and death in overdose. Symptoms may include confusion, hallucinations, coma, seizures, and respiratory arrest. Treatment may include gastric lavage, activated charcoal, and supportive measures to control symptoms.

Precaution

Tanin may cause drowsiness, dizziness, or blurred vision, and may impair physical or mental abilities required for the performance of potentially hazardous activities such as driving or operating machinery. Avoid these activities until you know how the drug affects you.

Interaction

Tanin may interact with other drugs, such as anticholinergics, cimetidine, fluvoxamine, fluoxetine, nefazodone, and MAO inhibitors. Tell your doctor all medications and supplements you are taking before taking tizanidine.

Disease Interaction

Tanin may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants.

Drug Interaction

Tanin can interact with other drugs, including Nefazodone, Cimetidine, Fluoxetine, Fluvoxamine, and Monoamine Oxidase inhibitors (MAOI). Tell your doctor all medications and supplements you are taking before taking tizanidine.

Food Interactions

Tanin may interact with food, beverages, or alcohol, causing side effects such as drowsiness, lightheadedness, dizziness, and blurred vision. Avoid these interactions by consuming tizanidine with food or at least 8 ounces of water.

Pregnancy Use

Tanin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Women who are pregnant or planning to become pregnant should inform their healthcare provider of this before taking tizanidine.

Lactation Use

Tanin should not be used by breastfeeding women due to the potential for serious adverse reactions in nursing babies. Talk to your healthcare provider if you are breastfeeding before taking tizanidine.

Acute Overdose

Acute overdose symptoms may include drowsiness, confusion, impaired coordination, low blood pressure, and slow heartbeat. Treatment may include gastric lavage, activated charcoal, and supportive measures. Seek emergency medical help if an overdose is suspected.

Contraindication

Tanin is contraindicated in patients with known hypersensitivity reactions to it, as well as those taking fluvoxamine, MAO inhibitors, or cimetidine.

Use Direction

Tanin should be taken orally, with food or immediately after a meal. For maximum benefit, the medication should be taken at regular intervals. Do not take more than directed or change the dose without consulting a doctor.

Storage Condition

Tanin should be stored at room temperature, away from direct light and moisture. Keep all medications away from children and pets.

Volume of Distribution

Tanin has a volume of distribution of 0.9 L/kg.

Half Life

The half-life of tizanidine is 2.5-4.6 hours.

Clearance

The clearance of tizanidine is 1.2-3.2 mL/min/kg.

Here you find in details version of Tanin

Some Frequently Asked Questions About Tanin

What is Tanin?

Tanin is a centrally acting alpha-2 agonist used to treat spasticity, a condition caused by an injury or illness that results in muscle stiffness, tightness, and spasms.

What is the most common use of Tanin?

The most common use of Tanin is to treat spasticity associated with neurological conditions such as multiple sclerosis, spinal cord injury, and cerebral palsy.

How long does it take for Tanin to start working?

Tanin usually starts to work within 30 minutes to an hour after taking it.

How should I take Tanin?

Take Tanin exactly as prescribed by your doctor. Do not take more or less than prescribed. Do not take more than 3 tablets per day.

How long does Tanin stay in your system?

Tanin has a half-life of approximately 1 to 2 hours, meaning it will typically stay in your system for up to 8 hours.

Can I take Tanin with other medications?

Tanin may interact with certain other medications so make sure to tell your doctor about all the other medications you are taking.

What are the possible side effects of taking Tanin?

Common side effects of taking Tanin include dry mouth, drowsiness, dizziness, weakness, and fatigue. More severe side effects including low blood pressure, slow heart rate, and liver damage may also occur.

Is Tanin addictive?

Tanin is not known to be habit-forming or addictive, but it is important to take it as directed by your doctor.

Can I drink alcohol while taking Tanin?

It is not recommended to drink alcohol while taking Tanin, as it can increase the risk of side effects.

Does Tanin treat muscle spasms?

Yes, Tanin can be used to treat muscle spasms caused by spasticity.

Can Tanin be used to relieve pain?

Tanin is mainly used to treat spasticity, but it can also be used to relieve pain associated with muscle spasms.

Who should not take Tanin?

Tanin should not be taken by pregnant women, children, or those with liver or kidney disease. Additionally, those taking certain other medications should not take Tanin.

Is Tanin safe for long-term use?

Tanin is generally safe for long-term use, but talk to your doctor if you have any concerns about taking this medication for an extended period of time.

Does Tanin cause weight gain?

In some cases, Tanin may cause weight gain. This is more likely to occur in elderly patients and those with kidney or liver disease.

Can I take Tanin while breastfeeding?

It is not recommended to take Tanin while breastfeeding, as it could pass into breast milk and affect the baby.

Can Tanin be used to treat headaches?

No, Tanin is not used to treat headaches. It is intended to treat spasticity caused by neurological conditions.

Does Tanin cause depression or anxiety?

In some cases, Tanin can cause depression or anxiety. If these side effects occur, speak with your doctor right away.

Is Tanin available in generic form?

Yes, Tanin is available in generic form.

How is Tanin metabolized in the body?

Tanin is metabolized in the liver by cytochrome P450 3A4.

Can Tanin cause stomach upset?

Yes, Tanin can cause stomach upset including nausea, vomiting, and diarrhea.

Can I take other medications with Tanin?

Certain medications should not be taken with Tanin, including medications used to treat epilepsy, depression and anxiety, and those containing cimetidine. Be sure to tell your doctor about all medications you are currently taking before starting Tanin.

Does Tanin interact with grapefruit juice?

Yes, Tanin can interact with grapefruit juice and increase the risk of side effects.

What happens if I miss a dose of Tanin?

If you miss a dose of Tanin, take it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular schedule.

Can Tanin be used to treat fibromyalgia?

Tanin is not traditionally used to treat fibromyalgia, but it may be recommended by your doctor in certain cases.

Can Tanin cause blurred vision?

Blurred vision is a possible side effect of taking Tanin.

What should I do if I experience an allergic reaction to Tanin?

If you experience any signs of an allergic reaction to Tanin such as itching, swelling, or difficulty breathing, seek medical attention immediately.

What should I do if I experience drowsiness while taking Tanin?

If you experience drowsiness while taking Tanin, it is recommended to avoid activities that require alertness such as driving or operating heavy machinery.

Is Tanin safe for children to take?

Tanin is not recommended for use in children. Speak with your doctor if you are considering giving this medication to a child.

What else should I know about taking Tanin?

Take Tanin exactly as directed by your doctor. Do not take more or less than prescribed. Do not take more than 3 tablets per day. Do not stop taking Tanin without first talking to your doctor. Be sure to tell your doctor about all medications you are currently taking.

Does Tanin cause cognitive impairment?

In some cases, Tanin may cause cognitive impairment such as confusion, memory problems, and difficulty concentrating.

Can Tanin be used to treat insomnia?

Tanin is not typically used to treat insomnia, but it can cause drowsiness in some cases which may help in falling and staying asleep.

Can I take Tanin if I have high blood pressure?

It is not recommended to take Tanin if you have high blood pressure, as it can cause further decreases in your blood pressure.

Can I take Tanin while pregnant?

It is not recommended to take Tanin while pregnant, as it may cause harm to the fetus.

Does Tanin contain sulfa?

No, Tanin does not contain sulfa.

Does Tanin cause memory loss?

In some cases, Tanin may cause memory loss and other cognitive impairments.

Does Tanin interact with other medications?

Yes, Tanin may interact with certain medications. Be sure to tell your doctor about all medications you are taking before starting Tanin.

Should Tanin be taken with food?

Tanin may be taken with or without food.

What are the most common side effects of taking Tanin?

The most common side effects of taking Tanin include dry mouth, drowsiness, dizziness, weakness, and fatigue.

What should I avoid while taking Tanin?

Avoid activities that require alertness such as driving or operating heavy machinery while taking Tanin due to its drowsiness-causing side effects.

What is the recommended dosage of Tanin for spasticity?

The recommended dosage of Tanin for spasticity is 2-4 mg per day, taken either 2 or 3 times a day depending on the doctor's recommendation.

Does Tanin cause difficulty urinating?

In some cases, Tanin may cause difficulty urinating due to its effects on sphincter muscles in the bladder.

Can I take Tanin with other muscle relaxants?

It is not recommended to take Tanin with other muscle relaxants, as this may increase the risk of side effects.