Suvorest
Suvorest Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Suvorest is a brand name. Its generic name is Suvorexant.
Suvorest
Suvorest is a medication that is used to treat insomnia. It is a type of sedative-hypnotic medication that acts on certain chemicals in the brain that are involved in sleep and wakefulness. It works by blocking certain receptors in the brain to help the patient stay asleep for a longer period of time.
Uses for Suvorest
Suvorest is used for the treatment of insomnia. It is commonly prescribed to people who have difficulty falling or staying asleep, or who wake up too early in the morning. This medication may be recommended for people with conditions such as jet lag, shift work-related insomnia, or trouble sleeping due to anxiety.
Mechanism of Action
Suvorest works by blocking certain receptors in the brain, specifically orexin receptors. Orexin receptors help regulate wakefulness and when they are blocked, the patient is less likely to stay awake. By blocking the orexin receptors with Suvorest, the patient is less likely to wake during the night and can sleep for a more restful and satisfying night’s sleep.
How Long Does it Take to Work
Suvorest usually starts to work within 30 minutes of taking it. It is important to take the medication at bedtime and to avoid taking it later in the night since that can make it harder to wake up in the morning.
Absorption
Suvorest is rapidly and completely absorbed after oral ingestion. Maximum concentrations are reached in about 3 hours.
Route of Elimination
Suvorest is eliminated primarily by the liver, with a half-life of approximately 12 hours.
Dosage
The recommended adult starting dose of Suvorest is 15 mg once daily at bedtime. The dose may be increased to 30 mg, if needed. You should not take more than 30 mg in a 24 hour period. It is important to take Suvorest exactly as prescribed. If you are unsure about your dose, contact your physician or pharmacist.
Administration
Suvorest should be taken at bedtime every day. It can be taken with or without food. Swallow the tablet whole with a full glass of water.
Side Effect
Common side effects of Suvorest include: fatigue, dizziness, nausea, dry mouth, headache, and constipation. Other side effects may include: confusion, loss of coordination, agitation, suicidal thoughts, hallucinations, and depression. Contact your physician if any side effects worsen or persist.
Toxicity
In studies, Suvorest has not been found to have any toxic effects when taken at the recommended doses. Overdose of Suvorest can be serious and it is important to seek medical attention right away if you believe you have taken too much of the medication.
Precaution
Before taking Suvorest, tell your physician if you have ever abused or been dependent on alcohol or other sedatives, have kidney or liver disease, have a history of depression or have thoughts of suicide or suicidal behavior.
Interaction
Suvorest may interact with other medications, including narcotics, alcohol, anti-anxiety medications, and muscle relaxants. It is important to tell your doctor about all medications you are taking.
Disease Interaction
Suvorest can interact with certain conditions, such as depression, anxiety, kidney or liver disease, or a history of drug or alcohol abuse. Talk to your doctor about any existing health conditions you may have before taking this medication.
Drug Interaction
Tell your healthcare provider if you are taking any other medications, including prescription and non-prescription medicines, vitamins, and herbal supplements. Certain medicines can interact with Suvorest and increase your risk of side effects.
Food Interactions
Suvorest can be taken with or without food. However, drinking alcohol or taking other medications that may make you sleepy, can increase the risk of side effects. Talk to your doctor before taking Suvorest with alcohol or other medications.
Pregnancy Use
Suvorest has not been studied in pregnant women so it is not recommended during this time. Talk to your doctor if you are pregnant or planning to become pregnant before taking this medication.
Lactation Use
Suvorest should not be taken by breastfeeding women, as it may pass into breast milk. Talk to your doctor about the risks and benefits of taking Suvorest during breastfeeding.
Acute Overdose
If you think you may have taken too much Suvorest, contact your healthcare provider or seek medical attention right away. Symptoms of an overdose may include extreme drowsiness, confusion, trouble breathing, coma, or seizures.
Contraindication
Suvorest should not be taken with other sleeping medications, alcohol, other sedatives, or narcotics. It should also not be taken if you have kidney or liver disease, or are pregnant or breastfeeding.
Use Direction
Suvorest should be taken as prescribed by your doctor. Take it at bedtime on an empty stomach, with a full glass of water. Do not take it more than once a day and do not take more than your prescribed dose. Do not take it if you are also taking any other medications or alcohol.
Storage Condition
Store Suvorest at room temperature in a dry place away from direct sunlight or heat. Keep it out of reach of children and away from pets.
Volume of Distribution
Suvorest is widely distributed throughout the body, with a median volume of distribution of 114 L/kg.
Half Life
The elimination half-life of Suvorest is approximately 12 hours.
Clearance
The clearance of Suvorest is very rapid and is primarily mediated through hepatic metabolism.
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