Sulindaco
Sulindaco Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sulindaco is a brand name. Its generic name is Sulindac.
Sulindaco
Sulindaco is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is used to reduce inflammation and pain associated with rheumatoid arthritis, ankylosing spondylitis, bursitis, and gout. Sulindaco may also be used to relieve pain caused by tension headaches and mild to moderate pain following surgical procedures.
Uses For Sulindaco
Sulindaco is indicated for the relief of the signs and symptoms of rheumatoid arthritis, ankylosing spondylitis, bursitis, and gout. It can also be used to reduce pain still associated with tension headaches and mild to moderate pain following surgical procedures.
Mechanism Of Action
Sulindaco works by blocking the action of cyclooxygenase enzymes, which in turn reduces the production of the prostaglandins that cause inflammation and pain. Sulindaco is a prodrug which is converted to sulindac sulfide in the liver by phase I metabolic pathways.
How Long Does It Take To Work?
It may take several days or weeks of taking Sulindaco for it to reach its maximum effectiveness. Generally, Sulindaco starts to work within a few days and its full effects may be seen within two to four weeks.
Absorption
Sulindaco is rapidly and nearly completely absorbed from the gastrointestinal tract.
Route Of Elimination
Sulindaco is eliminated mainly via the kidneys, with only a small amount being eliminated in the feces.
Dosage
The recommended adult dosage of Sulindaco is 150 mg to 300 mg taken orally twice per day. Dosage should be adjusted as needed depending on the individual's needs. However, the maximum recommended dose is 600 mg per day.
Administration
Sulindaco should be taken with food or milk to reduce stomach irritation. It should be taken with a full glass of water and may be taken with or without food. Do not break, crush, or chew the tablet. Do not take more than the recommended dose.
Side Effects
The most common side effects of Sulindaco include stomach upset, heartburn, nausea, diarrhea, constipation, headache, mild skin rash, and dizziness.
Toxicity
Sulindaco can be toxic when taken in large doses or for a long period of time. Signs of toxicity include dizziness, confusion, nausea, vomiting, abdominal pain, and loss of appetite.
Precaution
Patients with a history of allergies, asthma, kidney, or liver disease should inform their doctor prior to taking Sulindaco as it can worsen the symptoms of those conditions. Sulindaco should also be avoided in individuals with a history of bleeding disorders as it can increase the risk of bleeding. It is also important to inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
Interaction
It is important to inform your doctor and pharmacist of all medications that are being taken in order to avoid potential drug interactions with Sulindaco. Sulindaco may interact with other NSAIDs, corticosteroids, diuretics, SSRIs, and vasodilators.
Disease Interaction
Sulindaco may worsen the symptoms of certain diseases such as asthma, allergies, kidney disease, and liver disease. It is important to inform your doctor of any medical conditions you may have prior to taking Sulindaco.
Drug Interaction
Drug interactions may occur when Sulindaco is taken with other medications such as anticoagulants, SSRIs, aspirin, and corticosteroids. It is important to inform your doctor and pharmacist of all medications that are being taken in order to avoid potential drug interactions.
Food Interactions
Foods containing high amounts of salicylates such as raisins, apples, wine, and beer should be avoided while taking Sulindaco as these foods may increase the risk of stomach irritation.
Pregnancy Use
Sulindaco should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is important to inform your doctor if you are pregnant or planning to become pregnant.
Lactation Use
Sulindaco should not be used while breastfeeding as it may pass through breast milk and cause harm to the infant.
Acute Overdose
If an overdose of Sulindaco is suspected, it is important to seek medical attention immediately. Signs of a Sulindaco overdose can include dizziness, nausea, vomiting, and abdominal pain.
Contraindication
Sulindaco is contraindicated in patients with a history of allergy, asthma, kidney or liver disease, bleeding disorders, or uncontrolled hypertension.
Use Direction
Sulindaco should be taken orally, usually twice a day with food or milk. The dosage should be adjusted according to the individual's needs, but the maximum recommended daily dose is 600 mg.
Storage Condition
Sulindaco should be stored at room temperature, away from light and moisture. It should also be kept out of reach of children.
Volume of Distribution
The volume of distribution of Sulindaco is approximately 5.2 L/kg.
Half Life
The elimination half-life of Sulindaco is between 3 and 4 hours.
Clearance
The clearance of Sulindaco is approximately 3.2 L/h/kg.
Here you find in details version of Sulindaco
Some Frequently Asked Questions About Sulindaco
What is Sulindaco?
Sulindaco is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for treating rheumatoid arthritis, osteoarthritis, acute painful shoulder or other painful conditions.
What Does Sulindaco Do?
Sulindaco relieves pain and reduces inflammation, which helps decrease stiffness and joint swelling. It is typically used in long-term treatment.
How Should I Take Sulindaco?
Sulindaco is typically taken twice daily with food, as directed by your doctor. Take the medication exactly as prescribed in order to reduce the risk of stomach upset.
What Are The Possible Side Effects of Sulindaco?
Common side effects may include stomach upset, nausea, diarrhea, and heartburn. More serious side effects can include kidney and liver damage, allergies, and blood disorders. Make sure to inform your doctor of any side effects you experience.
What Should I Do If I Miss a Dose of Sulindaco?
If you miss a dose of Sulindaco, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
Can I Drink Alcohol While Taking Sulindaco?
Alcohol will increase the risk of stomach upset when taking Sulindaco. People taking Sulindaco should limit their alcoholic beverages or avoid them altogether.
Can I Take Sulindaco With Other Medications?
Before taking Sulindaco, tell your doctor about any other medicines, supplements, or vitamins you are taking. Taking Sulindaco with certain other medications can increase your risk of side effects.
Is Sulindaco Safe During Pregnancy?
Sulindaco should be avoided during pregnancy, as it can have serious adverse effects on the fetus. Talk to your doctor if you are taking Sulindaco and become pregnant.
What Should I Do If I Experience An Allergic Reaction To Sulindaco?
Stop taking Sulindaco immediately and seek medical attention if you experience any symptoms of an allergic reaction, such as hives, facial swelling, or breathing difficulties.
Should I Avoid Sun Exposure While Taking Sulindaco?
Yes. Sulindaco can make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing when outdoors to protect your skin.
What Is The Most Common Reason For Taking Sulindaco?
The most common reason for taking Sulindaco is to relieve pain and inflammation from various kinds of arthritis, including rheumatoid arthritis, osteoarthritis, and acute painful shoulder.
Is Sulindaco Addictive?
No. Sulindaco is not habit-forming and is not known to be addictive.
Can I Buy Sulindaco Over-the-Counter?
No. Sulindaco is a prescription-only medication, and should always be taken under the guidance of a doctor.
What Kind Of Tests Are Required Before Taking Sulindaco?
Your doctor may order blood tests or other tests before beginning Sulindaco to check for preexisting kidney, liver, or heart problems. Your doctor may also recommend regular blood tests to monitor your condition while taking Sulindaco.
What Are The Precautions To Observe While Taking Sulindaco?
The most important precaution is to take Sulindaco exactly as prescribed. Do not take higher doses or take them more often than recommended. Avoid drinking alcohol while taking Sulindaco. Make sure to inform your doctor of any medical conditions, including stomach ulcers, before taking Sulindaco.
Does Sulindaco Have An Expiration Date?
Yes. Sulindaco will expire after the date printed on the package. Make sure to check the expiration date and discard any medication that has expired.
What Happens If I Overdose On Sulindaco?
Overdosing on Sulindaco can be fatal. If you think you or someone else may have taken an overdose of Sulindaco, seek immediate medical attention.
Is Sulindaco Affected By Food And Drinks?
Sulindaco should be taken with food to reduce its potential for causing stomach upset. Grapefruit and grapefruit juice can interfere with Sulindaco so it should be avoided.
Is Sulindaco Safe For Children?
No. Sulindaco is not approved for use in children and should not be given to a child without the advice of a doctor.
Are There Any Long-Term Effects Of Taking Sulindaco?
Long-term use of Sulindaco has been linked to gastrointestinal bleeding, ulcers, and kidney or liver damage. Consult with your doctor if you have any concerns about long-term use.
Should I Take Sulindaco With Milk?
No. Milk should be avoided when taking Sulindaco as it may interfere with the absorption of the medication.
Should I Take Sulindaco With Antacids?
No. Antacids should not be taken at the same time as Sulindaco as they can interfere with the absorption of the medication.
Can I Take Other Pain Relief Drugs Along With Sulindaco?
No. Taking two different types of NSAIDs, including Sulindaco, can cause serious side effects. Talk to your doctor before combining Sulindaco with other medications.
Is Sulindaco Available In Liquid Form?
No. Sulindaco is only available in tablet form.
Can I Take Sulindaco With Aspirin?
No. Taking Sulindaco with aspirin can increase your risk of stomach irritation and gastrointestinal bleeding. Avoid taking other non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, at the same time as Sulindaco.
How Long Does Sulindaco Take To Work?
Sulindaco can start to work within an hour and can continue to work for up to 24 hours. Most people begin to experience relief within the first few days of taking Sulindaco, but it may take several weeks for the full effects to be seen.
Can Sulindaco Help Reduce Fever?
No. Sulindaco does not reduce fever and is not indicated for treating fever. Acetaminophen or ibuprofen may be used to reduce fever.
Will Sulindaco Help With Chronic Pain?
Yes. Sulindaco can be used to reduce chronic pain associated with arthritis and other conditions.
Is Sulindaco A Steroid?
No. Sulindaco is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).
Do I Need To Wear Sunscreen While Taking Sulindaco?
Yes. Sulindaco can make your skin more sensitive to sunlight. Use sunscreen or wear protective clothing when outdoors to protect your skin.
Is It Safe To Take Sulindaco For A Long Period Of Time?
Yes. While it is safe to take Sulindaco for a long period of time, it is important to speak to your doctor regularly about any side effects you may be experiencing.
Can Sulindaco Help With Acute Pain?
Yes. Sulindaco is commonly used to relieve acute pain, such as in the shoulder, knee, hip, or other joints.
Should I Take Sulindaco With Water?
Yes. Sulindaco should be taken with water to reduce its potential for causing stomach upset.
Can I Take Sulindaco With Vitamin Supplements?
Yes, however you should speak to your doctor before taking any vitamin supplements, especially if you have any health conditions.
What Are The Possible Interactions With Sulindaco?
Sulindaco may interact with other drugs or dietary supplements. Make sure to tell your doctor about any drugs or supplements you are taking before taking Sulindaco.
What Are The Common Uses Of Sulindaco?
Sulindaco is used to treat rheumatoid arthritis, osteoarthritis, and acute painful shoulder or other painful conditions, reduce pain and inflammation, and decrease stiffness and joint swelling.
How Long Until Sulindaco Reaches Its Full Effectiveness?
Most people begin to feel the effects of Sulindaco within the first few days of taking it, although it may take several weeks for the full effects to be seen.
Are There Any Alternatives To Taking Sulindaco?
Alternatives to taking Sulindaco include other non-steroidal anti-inflammatory drugs (NSAIDs), steroids, and over-the-counter pain relief medications such as acetaminophen or ibuprofen.