Sulindacum
Sulindacum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sulindacum is a brand name. Its generic name is Sulindac.
Sulindacum
Sulindacum is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is used to reduce inflammation and pain associated with rheumatoid arthritis, ankylosing spondylitis, bursitis, and gout. Sulindacum may also be used to relieve pain caused by tension headaches and mild to moderate pain following surgical procedures.
Uses For Sulindacum
Sulindacum is indicated for the relief of the signs and symptoms of rheumatoid arthritis, ankylosing spondylitis, bursitis, and gout. It can also be used to reduce pain still associated with tension headaches and mild to moderate pain following surgical procedures.
Mechanism Of Action
Sulindacum works by blocking the action of cyclooxygenase enzymes, which in turn reduces the production of the prostaglandins that cause inflammation and pain. Sulindacum is a prodrug which is converted to sulindac sulfide in the liver by phase I metabolic pathways.
How Long Does It Take To Work?
It may take several days or weeks of taking Sulindacum for it to reach its maximum effectiveness. Generally, Sulindacum starts to work within a few days and its full effects may be seen within two to four weeks.
Absorption
Sulindacum is rapidly and nearly completely absorbed from the gastrointestinal tract.
Route Of Elimination
Sulindacum is eliminated mainly via the kidneys, with only a small amount being eliminated in the feces.
Dosage
The recommended adult dosage of Sulindacum is 150 mg to 300 mg taken orally twice per day. Dosage should be adjusted as needed depending on the individual's needs. However, the maximum recommended dose is 600 mg per day.
Administration
Sulindacum should be taken with food or milk to reduce stomach irritation. It should be taken with a full glass of water and may be taken with or without food. Do not break, crush, or chew the tablet. Do not take more than the recommended dose.
Side Effects
The most common side effects of Sulindacum include stomach upset, heartburn, nausea, diarrhea, constipation, headache, mild skin rash, and dizziness.
Toxicity
Sulindacum can be toxic when taken in large doses or for a long period of time. Signs of toxicity include dizziness, confusion, nausea, vomiting, abdominal pain, and loss of appetite.
Precaution
Patients with a history of allergies, asthma, kidney, or liver disease should inform their doctor prior to taking Sulindacum as it can worsen the symptoms of those conditions. Sulindacum should also be avoided in individuals with a history of bleeding disorders as it can increase the risk of bleeding. It is also important to inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
Interaction
It is important to inform your doctor and pharmacist of all medications that are being taken in order to avoid potential drug interactions with Sulindacum. Sulindacum may interact with other NSAIDs, corticosteroids, diuretics, SSRIs, and vasodilators.
Disease Interaction
Sulindacum may worsen the symptoms of certain diseases such as asthma, allergies, kidney disease, and liver disease. It is important to inform your doctor of any medical conditions you may have prior to taking Sulindacum.
Drug Interaction
Drug interactions may occur when Sulindacum is taken with other medications such as anticoagulants, SSRIs, aspirin, and corticosteroids. It is important to inform your doctor and pharmacist of all medications that are being taken in order to avoid potential drug interactions.
Food Interactions
Foods containing high amounts of salicylates such as raisins, apples, wine, and beer should be avoided while taking Sulindacum as these foods may increase the risk of stomach irritation.
Pregnancy Use
Sulindacum should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is important to inform your doctor if you are pregnant or planning to become pregnant.
Lactation Use
Sulindacum should not be used while breastfeeding as it may pass through breast milk and cause harm to the infant.
Acute Overdose
If an overdose of Sulindacum is suspected, it is important to seek medical attention immediately. Signs of a Sulindacum overdose can include dizziness, nausea, vomiting, and abdominal pain.
Contraindication
Sulindacum is contraindicated in patients with a history of allergy, asthma, kidney or liver disease, bleeding disorders, or uncontrolled hypertension.
Use Direction
Sulindacum should be taken orally, usually twice a day with food or milk. The dosage should be adjusted according to the individual's needs, but the maximum recommended daily dose is 600 mg.
Storage Condition
Sulindacum should be stored at room temperature, away from light and moisture. It should also be kept out of reach of children.
Volume of Distribution
The volume of distribution of Sulindacum is approximately 5.2 L/kg.
Half Life
The elimination half-life of Sulindacum is between 3 and 4 hours.
Clearance
The clearance of Sulindacum is approximately 3.2 L/h/kg.
Here you find in details version of Sulindacum
Some Frequently Asked Questions About Sulindacum
What is Sulindacum?
Sulindacum is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for treating rheumatoid arthritis, osteoarthritis, acute painful shoulder or other painful conditions.
What Does Sulindacum Do?
Sulindacum relieves pain and reduces inflammation, which helps decrease stiffness and joint swelling. It is typically used in long-term treatment.
How Should I Take Sulindacum?
Sulindacum is typically taken twice daily with food, as directed by your doctor. Take the medication exactly as prescribed in order to reduce the risk of stomach upset.
What Are The Possible Side Effects of Sulindacum?
Common side effects may include stomach upset, nausea, diarrhea, and heartburn. More serious side effects can include kidney and liver damage, allergies, and blood disorders. Make sure to inform your doctor of any side effects you experience.
What Should I Do If I Miss a Dose of Sulindacum?
If you miss a dose of Sulindacum, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
Can I Drink Alcohol While Taking Sulindacum?
Alcohol will increase the risk of stomach upset when taking Sulindacum. People taking Sulindacum should limit their alcoholic beverages or avoid them altogether.
Can I Take Sulindacum With Other Medications?
Before taking Sulindacum, tell your doctor about any other medicines, supplements, or vitamins you are taking. Taking Sulindacum with certain other medications can increase your risk of side effects.
Is Sulindacum Safe During Pregnancy?
Sulindacum should be avoided during pregnancy, as it can have serious adverse effects on the fetus. Talk to your doctor if you are taking Sulindacum and become pregnant.
What Should I Do If I Experience An Allergic Reaction To Sulindacum?
Stop taking Sulindacum immediately and seek medical attention if you experience any symptoms of an allergic reaction, such as hives, facial swelling, or breathing difficulties.
Should I Avoid Sun Exposure While Taking Sulindacum?
Yes. Sulindacum can make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing when outdoors to protect your skin.
What Is The Most Common Reason For Taking Sulindacum?
The most common reason for taking Sulindacum is to relieve pain and inflammation from various kinds of arthritis, including rheumatoid arthritis, osteoarthritis, and acute painful shoulder.
Is Sulindacum Addictive?
No. Sulindacum is not habit-forming and is not known to be addictive.
Can I Buy Sulindacum Over-the-Counter?
No. Sulindacum is a prescription-only medication, and should always be taken under the guidance of a doctor.
What Kind Of Tests Are Required Before Taking Sulindacum?
Your doctor may order blood tests or other tests before beginning Sulindacum to check for preexisting kidney, liver, or heart problems. Your doctor may also recommend regular blood tests to monitor your condition while taking Sulindacum.
What Are The Precautions To Observe While Taking Sulindacum?
The most important precaution is to take Sulindacum exactly as prescribed. Do not take higher doses or take them more often than recommended. Avoid drinking alcohol while taking Sulindacum. Make sure to inform your doctor of any medical conditions, including stomach ulcers, before taking Sulindacum.
Does Sulindacum Have An Expiration Date?
Yes. Sulindacum will expire after the date printed on the package. Make sure to check the expiration date and discard any medication that has expired.
What Happens If I Overdose On Sulindacum?
Overdosing on Sulindacum can be fatal. If you think you or someone else may have taken an overdose of Sulindacum, seek immediate medical attention.
Is Sulindacum Affected By Food And Drinks?
Sulindacum should be taken with food to reduce its potential for causing stomach upset. Grapefruit and grapefruit juice can interfere with Sulindacum so it should be avoided.
Is Sulindacum Safe For Children?
No. Sulindacum is not approved for use in children and should not be given to a child without the advice of a doctor.
Are There Any Long-Term Effects Of Taking Sulindacum?
Long-term use of Sulindacum has been linked to gastrointestinal bleeding, ulcers, and kidney or liver damage. Consult with your doctor if you have any concerns about long-term use.
Should I Take Sulindacum With Milk?
No. Milk should be avoided when taking Sulindacum as it may interfere with the absorption of the medication.
Should I Take Sulindacum With Antacids?
No. Antacids should not be taken at the same time as Sulindacum as they can interfere with the absorption of the medication.
Can I Take Other Pain Relief Drugs Along With Sulindacum?
No. Taking two different types of NSAIDs, including Sulindacum, can cause serious side effects. Talk to your doctor before combining Sulindacum with other medications.
Is Sulindacum Available In Liquid Form?
No. Sulindacum is only available in tablet form.
Can I Take Sulindacum With Aspirin?
No. Taking Sulindacum with aspirin can increase your risk of stomach irritation and gastrointestinal bleeding. Avoid taking other non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, at the same time as Sulindacum.
How Long Does Sulindacum Take To Work?
Sulindacum can start to work within an hour and can continue to work for up to 24 hours. Most people begin to experience relief within the first few days of taking Sulindacum, but it may take several weeks for the full effects to be seen.
Can Sulindacum Help Reduce Fever?
No. Sulindacum does not reduce fever and is not indicated for treating fever. Acetaminophen or ibuprofen may be used to reduce fever.
Will Sulindacum Help With Chronic Pain?
Yes. Sulindacum can be used to reduce chronic pain associated with arthritis and other conditions.
Is Sulindacum A Steroid?
No. Sulindacum is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).
Do I Need To Wear Sunscreen While Taking Sulindacum?
Yes. Sulindacum can make your skin more sensitive to sunlight. Use sunscreen or wear protective clothing when outdoors to protect your skin.
Is It Safe To Take Sulindacum For A Long Period Of Time?
Yes. While it is safe to take Sulindacum for a long period of time, it is important to speak to your doctor regularly about any side effects you may be experiencing.
Can Sulindacum Help With Acute Pain?
Yes. Sulindacum is commonly used to relieve acute pain, such as in the shoulder, knee, hip, or other joints.
Should I Take Sulindacum With Water?
Yes. Sulindacum should be taken with water to reduce its potential for causing stomach upset.
Can I Take Sulindacum With Vitamin Supplements?
Yes, however you should speak to your doctor before taking any vitamin supplements, especially if you have any health conditions.
What Are The Possible Interactions With Sulindacum?
Sulindacum may interact with other drugs or dietary supplements. Make sure to tell your doctor about any drugs or supplements you are taking before taking Sulindacum.
What Are The Common Uses Of Sulindacum?
Sulindacum is used to treat rheumatoid arthritis, osteoarthritis, and acute painful shoulder or other painful conditions, reduce pain and inflammation, and decrease stiffness and joint swelling.
How Long Until Sulindacum Reaches Its Full Effectiveness?
Most people begin to feel the effects of Sulindacum within the first few days of taking it, although it may take several weeks for the full effects to be seen.
Are There Any Alternatives To Taking Sulindacum?
Alternatives to taking Sulindacum include other non-steroidal anti-inflammatory drugs (NSAIDs), steroids, and over-the-counter pain relief medications such as acetaminophen or ibuprofen.