Spartic

Spartic Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Spartic is a brand name. Its generic name is Sparfloxacin.

Spartic Introduction

Spartic is a synthetic quinolone fluoropyrimidine antibiotic drug used to treat infections caused by bacteria. It is used to treat respiratory and urinary tract infections, skin and soft tissue infections, sexually transmitted diseases and ear infections. It is also used to prevent infection prior to surgery.

Spartic Uses and Mechanism of Action

Spartic works by inhibiting the bacterial enzyme DNA gyrase, which is responsible for the synthesis and repair of bacterial DNA and important to the growth of bacteria. DNA gyrase is an integral part of the DNA replication process and is also responsible for its supercoiling. Inhibition of this enzyme leads to an inhibition of bacterial growth and proliferation of bacterial cells.

How Long Does it Take to Work?

The effects of Spartic can be seen within a day of starting the treatment. Most bacterial infections will start to show signs of improvement within 24 to 48 hours of starting the medication although in some cases, it may take up to one week for the infection to clear completely.

Spartic Absorption, Route of Elimination, and Volume of Distribution

Spartic is rapidly and completely absorbed after oral administration, and its bioavailability is almost 100%. It is rapidly metabolized and eliminated in the urine where more than 90% of a given dose is excreted within 24 hours.

The apparent volume of distribution of Spartic is 7.8–14.0 liters and the plasma clearance is 8–13 liters/hr.

Spartic Dosage and Administration

The usual dosage for adults is 200 milligrams (mg) once daily. For children aged between 1 and 12, the dose is 10–20 mg/kg daily, given in two divided doses. For children aged over 12 and adults, the daily dose is 200–400 mg, given in two divided doses.

Spartic should be taken with a full glass of water. It should be taken either 1 hour before or after meals.

Spartic Side Effects, Toxicity, and Precautions

The most common side effects of Spartic include vomiting, nausea, stomach pain, headache, dizziness and rash. Rare but serious side effects include allergic reactions and tendon problems.

Spartic is generally safe when taken as directed. However, it should be used with caution in pregnant or nursing women, as it can harm a fetus or infant.

Spartic is toxic to the kidneys and should be used with caution in patients with kidney damage.

Spartic Interactions

People taking Spartic should avoid taking antacids, anticonvulsants, iron supplements, and mao inhibitors as these medications may interact adversely with Spartic.

Spartic can also interact with other medications, including certain antibiotics, antifungals, diuretics, and cholesterol-lowering drugs.

Spartic Disease Interactions, Drug Interactions, and Food Interactions

People with pre-existing liver or kidney disease should not take Spartic. The amount of Spartic in the body may increase if it is taken with certain other medications that can decrease the amount of potassium or magnesium in the body.

Spartic should not be taken with dairy products or foods fortified with calcium as it can reduce the absorption of the drug. Spartic may also interact with grapefruit juice, alcohol, and caffeine.

Spartic Pregnancy and Lactation Use

Spartic should not be used during pregnancy. It should also not be used while breastfeeding, as it may pass into breast milk and harm a nursing baby.

Spartic Acute Overdose

A single overdose of Spartic is not likely to cause serious harm. However, if multiple doses are taken in one day, it may cause vomiting, dizziness, seizures, confusion, abdominal pain, and a drop in blood pressure.

Spartic Contraindications and Use Direction

Spartic should not be used in patients with a known hypersensitivity to the medication. It should also not be taken in patients with severe kidney impairment.

Spartic may be taken with or without food, but it should not be taken with antacids, anticonvulsants, iron supplements, or mao inhibitors.

Spartic Storage Condition, Half Life, and Clearance

Spartic should be stored at room temperature, away from light and moisture. It has a plasma half-life of 7 to 10 hours and is completely metabolized by the liver and excreted in the urine.

Here you find in details version of Spartic

Some Frequently Asked Questions About Spartic

What is Spartic?

Spartic is a synthetic fluoroquinolone antibiotic used to treat bacterial infections.

How does Spartic work?

Spartic works by interfering with the ability of bacteria to reproduce. It does this by targeting an enzyme called topoisomerase which helps the bacteria replicate DNA.

What kinds of bacterial infections can Spartic treat?

Spartic is used to treat a number of different bacterial infections, including airway infections, skin and soft tissue infections, pneumonia, otitis media, and urinary tract infections.

Is Spartic a safe drug?

Spartic is generally safe when taken as directed. However, due to a risk of serious adverse effects, it should not be used in pregnant or nursing women, or children less than 18 years of age.

What are the side effects of Spartic?

Common side effects of Spartic include nausea, headache, dizziness, lightheadedness, abdominal pain, diarrhea, and rash. In rare cases, more serious side effects such as liver toxicity, tendon rupture, or arrhythmias may occur.

Is Spartic a generic drug?

Spartic is the brand name of a fluoroquinolone antibiotic manufactured by Zydus Cadila. It is not available in generic form.

Is Spartic a prescription drug?

Yes, Spartic is a prescription drug and must be prescribed by a doctor.

Does Spartic need to be taken with food?

No, Spartic does not need to be taken with food. It can be taken with or without food, but should be taken with a full glass of water.

What is the recommended dosage of Spartic?

The recommended dose of Spartic for adults is 200 mg once daily for 7-10 days, depending on the type of infection being treated. Your doctor may adjust the dose depending on your response to treatment.

What if I miss a dose of Spartic?

If you miss a dose of Spartic, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can I take Spartic with other medications?

It is important to tell your doctor about any other medications, supplements, or herbal remedies you are taking, as they may interact with Spartic. Certain medications may increase your risk of side effects or reduce the effectiveness of Spartic.

What should I do if I experience side effects from Spartic?

If you experience any side effects while taking Spartic, contact your doctor immediately. In the event of an allergic reaction, seek emergency medical help.

What should I do if I overdose on Spartic?

If you or someone else has taken an overdose of Spartic, seek emergency medical help immediately. Overdose symptoms may include nausea, vomiting, seizure, confusion, and difficulty breathing.

Should I avoid certain foods or activities while taking Spartic?

You should avoid activities that might put you at risk of a sunburn while taking Spartic, as it can make your skin more sensitive to sunlight. You should also avoid consuming dairy products or calcium supplements within 2 hours of taking Spartic.

Can I drink alcohol while taking Spartic?

It is not recommended to drink alcohol while taking Spartic due to an increased risk of side effects. If you must drink alcohol, it should be done in moderation.

How long does it take for Spartic to work?

It may take up to 48 hours for Spartic to start working, but it should improve your symptoms within several days of starting the medication. Follow your doctor's instructions for taking Spartic.

How should Spartic be stored?

Spartic should be stored at room temperature away from light and moisture. Keep it in the original container it came in and out of reach of children.

Is it safe to use Spartic during pregnancy?

No, it is not recommended to use Spartic during pregnancy due to the risk of serious adverse effects. If you are pregnant or planning to become pregnant, tell your doctor before taking Spartic.

What should I do if I develop allergic symptoms while taking Spartic?

If you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, contact your doctor immediately. Your doctor may advise you to stop taking Spartic and switch to a different antibiotic.

Does Spartic interact with any other drugs?

Yes, Spartic can interact with other drugs, including antacids, nonsteroidal anti-inflammatory drugs, and drugs that contain magnesium, aluminum, or calcium. Your doctor should be aware of all drugs you are taking before prescribing Spartic.

Should I take probiotics while taking Spartic?

It is generally recommended to take probiotics while taking Spartic as it can help restore the balance of bacteria in the gut. Before taking probiotics, it is important to consult your doctor.

Can I take Spartic for travelers' diarrhea?

Yes, Spartic may be used to treat travelers' diarrhea if caused by bacteria. It is important to check with your doctor before taking any medication for travelers' diarrhea.

Does Spartic affect birth control?

Yes, Spartic may reduce the effectiveness of certain types of birth control, including the birth control pill and contraceptive injections. It is important to use a backup form of birth control while taking Spartic.

Does Spartic cause photosensitivity?

Yes, Spartic may increase your sensitivity to sunlight, which can lead to skin reactions. To minimize this risk, it is important to wear protective clothing, use sunscreen, and avoid artificial sources of light such as tanning beds while taking Spartic.

Does Spartic have any drug interactions with antacids?

Yes, Spartic may interact with certain antacids, such as famotidine and cimetidine, which can reduce the absorption and effectiveness of Spartic. It is important to talk to your doctor about any antacids you are taking before starting Spartic.

Is it safe to take Spartic if I have a history of kidney disease?

It is generally not recommended to take Spartic if you have a history of kidney disease. If your doctor prescribes Spartic, your kidney function will need to be monitored closely.

Does Spartic interact with other fluoroquinolones?

Yes, Spartic may interact with other fluoroquinolones, such as ciprofloxacin. It is important to tell your doctor if you are taking any other fluoroquinolones before taking Spartic.

Should I take Spartic if I am breastfeeding?

No, Spartic is not recommended for use in breastfeeding women due to a risk of harm to the baby. If you are a nursing mother, talk to your doctor about alternative treatments.

How long will Spartic stay in my system?

The half-life of Spartic is 6-8 hours, which means it generally takes about 36-48 hours for Spartic to be completely eliminated from the body. However, the actual time can vary depending on individual factors.

Is Spartic safe for use in children?

No, Spartic is not recommended for use in children under 18 years of age due to a risk of serious side effects. Alternative antibiotic treatments should be considered for use in children.

Does Spartic cause gastrointestinal disturbances?

Yes, Spartic may cause gastrointestinal disturbances, such as nausea, vomiting, diarrhea, and abdominal pain. If you experience such symptoms, talk to your doctor about ways to manage them.

Can I take Spartic while taking blood thinners?

No, it is not recommended to take Spartic while taking blood thinners, such as warfarin or coumarin, as there is a risk of increasing the risk of bleeding or bruising. If your doctor prescribes Spartic, your blood clotting should be monitored closely.

Does Spartic cause changes in your sense of taste?

Yes, Spartic may cause changes in your sense of taste. If you experience an altered taste, talk to your doctor about ways to manage it, such as taking a multivitamin or avoiding certain foods.

Can I take Spartic while taking steroids?

No, it is not recommended to take Spartic while taking steroids, as they may interact and increase the risk of side effects. Your doctor can advise you on an alternative treatment plan if necessary.

Can I take Spartic while taking a sulfonamide?

No, it is not recommended to take Spartic while taking a sulfonamide, as they may interact and increase the risk of side effects. Your doctor can advise you on an alternative treatment plan if necessary.

Can I take Spartic while taking probenecid?

No, it is not recommended to take Spartic while taking probenecid, as they may interact and increase the risk of side effects. Your doctor can advise you on an alternative treatment plan if necessary.

Does Spartic interact with any herbal supplements?

Yes, Spartic may interact with some herbal supplements, such as ginseng, St. John’s wort, and kava kava, which can reduce the effectiveness of Spartic. Before taking any herbal supplements, it is important to talk to your doctor.

Is Spartic a good choice for treating infections that are resistant to other antibiotics?

Yes, Spartic is effective in treating infections that are resistant to other antibiotics. However, it is important to discuss any existing resistance to antibiotics with your doctor before taking Spartic.

Does Spartic cause bone or joint pain?

Yes, Spartic may cause joint or bone pain in some patients. If you experience joint or bone pain, talk to your doctor about ways to manage it, such as taking an over-the-counter pain reliever.

Can I take Spartic if I have a history of heart disease?

Yes, Spartic can be taken if you have a history of heart disease. However, your doctor should monitor your heart function closely while taking Spartic.