Senacept
Senacept Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Senacept is a brand name. Its generic name is Cinacalcet.
Introduction
Senacept is a prescription drug currently approved by the Food and Drug Administration (FDA) for treating problems associated with hyperparathyroidism. It is a member of the group of drugs known as calcimimetics and its generic name is cinacalcet hydrochloride. This drug blocks certain receptors on parathyroid cells to help prevent the overproduction of parathyroid hormones. Senacept has also been used off-label for treatment of secondary hyperparathyroidism in patients receiving dialysis treatment.Uses for
Senacept is used to lower high blood calcium levels caused by overactive parathyroid glands in people with certain kidney diseases. It is generally used in conjunction with other medications and can help reduce the need for surgery to remove the overactive parathyroid gland. Senacept may be used to control hyperparathyroidism, secondary hyperparathyroidism due to kidney disease, and hypercalcemia in people with cancer.Mechanism of Action
Senacept works by binding to calcium-sensing receptors in the parathyroid gland and blocking their ability to detect calcium. This prevents the parathyroid gland from producing excessive amounts of parathyroid hormone (PTH). By blocking the receptors, Senacept reduces the level of calcium in the blood, which helps to control the symptoms associated with hyperparathyroidism.How long does it take to work?
It can take several weeks for Senacept to start working. It is important to take the medication as prescribed by your healthcare provider, and it may take some time for your PTH level to reach a normal range.Absorption, Route of Elimination, Dosage
Senacept is available as an oral tablet and is rapidly absorbed from the small intestine. The elimination half-life ranges from 3 to 6 hours. The recommended dosage range is 30 to 120 mg once daily.Administration
Senacept should be taken by mouth as directed by your healthcare provider. It is important to take the medication as prescribed by your healthcare provider and to follow the directions on the prescription label.Side Effect
Common side effects associated with Senacept include nausea, headache, diarrhea, vomiting, constipation, and muscle weakness. More serious side effects may include hypocalcemia, bone fractures, and kidney problems.Toxicity
If too much of the drug is taken, the effects can become toxic. The most serious concern is that Senacept may cause kidney failure or bone fractures. It is important to follow the dosage prescribed by your healthcare provider and keep regular appointments to monitor your condition.Precaution, Interaction, Disease Interaction, Drug Interaction, Food Interactions, Pregnancy Use, Lactationuse, Acute Overdose, Contraindication, Use Direction, Storage Condition, Volume Of Distribution, Half Life, Clearance
Precaution: Before taking Senacept, tell your doctor or pharmacist if you are allergic to it; or to other calcimimetics; or if you have any other allergies. Interaction: Senacept has been known to interact with certain medications such as diuretics, antacids, vitamin D supplements, and certain antibiotics. Disease Interaction: Senacept should be used cautiously in people with kidney disease, lupus, diabetes, or congestive heart failure. Drug Interaction: Senacept should be administered cautiously with other drugs that can raise or lower potassium levels or act on the parathyroid glands. Food Interactions: Senacept may interact with certain foods that contain high levels of calcium or Vitamin D, so it is important to consult with your healthcare provider before taking this medication. Pregnancy Use: Senacept should be used with caution during pregnancy because of the potential risks to the unborn infant. Lactation Use: Senacept should not be used during nursing mothers due to the lack of available data on its safety in breastfeeding infants. Acute Overdose: If an overdose of Senacept is suspected, seek medical attention immediately. Contraindication: Senacept is contraindicated in patients with known hypersensitivity to cinacalcet or other drugs of the same class. Use Direction: Senacept should be taken orally once daily as directed by your healthcare provider. The recommended dosage range is 30 to 120 mg once daily. Storage Conditions: Store at room temperature away from moisture and heat. Volume of Distribution: Senacept has a volume of distribution of about 45 L/kg. Half Life: Senacept has a half-life of about 3 to 6 hours. Clearance: Senacept has an estimated clearance of about 54 mL/min/kg.Here you find in details version of Senacept
Some Frequently Asked Questions About Senacept
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