Keflex

Keflex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Keflex is a brand name. Its generic name is Cephalexin.

Introduction

Keflex is an antibiotic drug belonging to the cephalosporin class. It is used to treat bacterial infections caused by susceptible Gram-positive bacteria, including skin, respiratory, urinary tract, and bone infections. It is also often prescribed as an off-label remedy for UTI infections, acne, impetigo, and gum diseases.

Uses for

Keflex is primarily used in the treatment of infections caused by Gram-positive bacteria, such as streptococci and staphylococci. Some off-label uses for cephalexin include treatment of impetigo, gum diseases, and urinary tract infections.

Mechanism of Action

Keflex works by inhibiting the synthesis of peptidoglycan, which is an essential component of the bacterial cell wall. This action makes the cell wall weak and susceptible to destruction, leading to death of the bacterial cells.

How Long Does It Take To Work?

Keflex starts to work within 1 to 2 hours of taking the medicine. Symptoms of an infection should start to improve within a few days of taking the medication.

Absorption

Keflex is rapidly and completely absorbed following oral administration.

Route of Elimination

Keflex is eliminated through the kidneys by glomerular filtration and tubular secretion.

Dosage Information

Keflex is available in oral tablets and capsules in dosages of 250, 500, and 750 mg. For skin, bone, and urinary tract infections, the usual dose is 250-500mg twice daily or 500-750mg once daily. For respiratory infections, the usual dose is 250-500mg every 6-8 hours or 500-750mg every 12 hours.

Administration

Keflex should be taken with food and plenty of fluids to help prevent irritation of the stomach and intestines. If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.

Side Effects

Common side effects of Keflex include nausea, vomiting, and diarrhea. Other side effects include rash, dizziness, headache, and abdominal pain. In rare cases, Keflex may also cause allergic reactions or liver damage. Call your doctor right away if you experience any unusual or severe symptoms.

Toxicity

Keflex is considered to be safe and well-tolerated. However, an overdose may lead to nausea, vomiting, and diarrhea. Severe overdose may result in liver damage, kidney damage, and coma.

Precaution

Patients with kidney and/or liver disease, asthma, and pregnant or breastfeeding women should take Keflex with caution, as they are more susceptible to its side effects. As the drug may interact with other medications, it is important to inform your physician if you are on any other medication, including over the counter drugs.

Interaction

Keflex may interact with other drugs and should not be administered with drugs that reduce the activity of bacteria, such as tetracyclines and macrolide antibiotics.

Disease Interaction

Keflex may interact with certain chronic diseases, such as kidney and liver disease. Patients with kidney or liver disease should take the medication with caution and under medical supervision.

Drug Interaction

Keflex may interact with other drugs, such as penicillin, tetracyclines, and macrolide antibiotics. It may also interact with drugs that reduce the activity of bacteria, such as chloramphenicol, probenecid, and allopurinol. It is important to inform your physician if you are taking any other medication before taking cephalexin.

Food Interactions

Keflex may interact with food and beverages. Taking it with food may decrease its effectiveness. It should not be taken with alcohol.

Pregnancy Use

Pregnant women should take cephalexin with caution and only after consulting their physician. This drug can be used during pregnancy if deemed necessary by the physician.

Lactation Use

Keflex should be used with caution in lactating women. It should not be used during the first trimester of pregnancy.

Acute Overdose

An overdose of cephalexin may lead to nausea, vomiting, and diarrhea. Severe overdoses may cause liver damage, kidney damage, and even coma in rare cases. Seek medical attention right away if you suspect an overdose.

Contraindication

Keflex should not be used in patients with known hypersensitivity or allergy to cephalosporins. It should also not be used in patients with kidney and liver disease.

Use Direction

Keflex should be used as directed by a physician. Take it with food and plenty of fluids to help prevent stomach irritation. Do not skip doses or stop taking the drug even if symptoms improve.

Storage Condition

Keflex should be stored at room temperature, away from heat and moisture. Keep all medicines out of reach of children.

Volume of Distribution

Keflex has a volume of distribution of 0.14-0.25 L/kg.

Half Life

The half life of cephalexin is 0.9-1.2 hours.

Clearance

The clearance of cephalexin is 0.07-0.55 L/h/kg.

Here you find in details version of Keflex

Some Frequently Asked Questions About Keflex

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What is Keflex?

Keflex is a type of medication known as a cephalosporin antibiotic. It is used to treat certain types of bacteria infections.

What are the uses of Keflex?

Keflex is used to treat a wide range of bacterial infections in the body. These include infections of the skin, respiratory tract, urinary tract, ears, and bones. It can also be used to prevent or treat certain bacterial infections in the lungs.

What is the usual dosage of Keflex?

The usual dosage of Keflex is 250 mg every 6-8 hours for adults. The dosage may vary based on age, weight, and condition of the patient.

What are the side effects of Keflex?

The most common side effects of Keflex include nausea, vomiting, diarrhea, headache, and rash. More serious side effects include abdominal pain, difficulty breathing, dizziness, and seizures.

Is Keflex safe for pregnant women?

Keflex is safe for pregnant women when taken as directed by your doctor. It is important to tell your doctor if you are pregnant before taking this medication.

Can Keflex be used to treat a sinus infection?

Yes, Keflex can be used to treat a sinus infection. It works by killing the bacteria that cause the infection.

What should I do if I miss a dose of Keflex?

If you miss a dose of Keflex, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

Is Keflex effective against strep throat?

Yes, Keflex is effective against strep throat. It can be used to treat strep throat, as well as other bacterial infections.

What should be avoided while taking Keflex?

You should avoid alcohol while taking Keflex as it can increase the risk of side effects. You should also avoid taking other medications that can interact with Keflex such as antacids or probenecid.

Should I take Keflex with food?

You may take Keflex with food or on an empty stomach. However, taking it with food may help to reduce the risk of side effects.

Does Keflex interact with any other medications?

Yes, Keflex can interact with other medications, including some antibiotics. It is important to tell your doctor about any other medications you are taking before taking Keflex.

What other forms does Keflex come in?

Keflex is available as tablets, capsules, suspension, and as an injection. It is important to follow your doctor's instructions for taking the medication.

Is Keflex safe for children?

Yes, Keflex is safe for children when taken as directed. Your doctor will adjust the dosage depending on your child's age, weight, and medical condition.

What is the shelf life of Keflex?

The shelf life of Keflex depends on the specific formulation and dosage form. Generally, tablets, capsules, and suspension have a shelf life of 3-5 years.

Is Keflex a penicillin?

No, Keflex is not a penicillin. It belongs to a group of medications called cephalosporin antibiotics.

Is Keflex safe for people with kidney problems?

Yes, Keflex is safe for people with kidney problems when taken as prescribed by your doctor. Your doctor may adjust the dosage depending on your condition.

Is Keflex an over-the-counter medication?

No, Keflex is not an over-the-counter medication and must be prescribed by your doctor.

Can Keflex be used to treat urinary tract infections?

Yes, Keflex can be used to treat urinary tract infections. It works by killing the bacteria that cause the infection.

Can Keflex treat a tooth infection?

Yes, Keflex can be used to treat a tooth infection. However, it is important to consult your doctor or dentist for the correct diagnosis and treatment.

Do I need to finish the full course of Keflex?

Yes, it is important to finish the full course of Keflex as prescribed by your doctor. This will help to ensure that your infection is fully treated and will help to prevent any resistance to the medication.

Can I take Keflex while I am breastfeeding?

Yes, Keflex is safe to take while breastfeeding. However, you should tell your doctor if you are breastfeeding before taking this medication.

Is Keflex effective against viral infections?

No, Keflex is not effective against viral infections as it is an antibiotic, which only works on bacterial infections.

Can Keflex treat a strep throat?

Yes, Keflex can be used to treat strep throat and other bacterial infections.

Should I avoid any food while taking Keflex?

You should avoid eating dairy products such as milk, cheese, or yogurt while taking Keflex as they can reduce the effectiveness of the medication.

Can Keflex be used to treat a bacterial sinus infection?

Yes, Keflex can be used to treat a bacterial sinus infection. It works by killing the bacteria that cause the infection.

Can Keflex treat a chest infection?

Yes, Keflex can be used to treat a chest infection. You should see your doctor if the infection persists for more than five days or if it worsens.

Can Keflex cause an allergic reaction?

Yes, Keflex can cause an allergic reaction in some people. Symptoms of an allergic reaction include itching, rash, difficulty breathing, and swelling of the face, lips, or tongue.

Can Keflex be taken on an empty stomach?

Yes, Keflex can be taken on an empty stomach. However, taking it with food may help to reduce the risk of side effects.

Can Keflex cause diarrhea?

Yes, Keflex can cause diarrhea in some people. It is important to drink plenty of fluids while taking this medication to help prevent dehydration.

What is the recommended dose of Keflex for adults?

The recommended dose of Keflex for adults is 250 mg every 6-8 hours. Your doctor may adjust the dose depending on your age, weight, and medical condition.

Can Keflex cause yeast infections?

Yes, Keflex can cause yeast infections in some people. It is important to tell your doctor if you experience any signs of a yeast infection such as itching, burning, or white patches.

How long does it take for Keflex to work?

Keflex usually starts to work within one to two hours of taking the medication. Results can vary based on the type of infection and person's individual response to the medication.

How long should I take Keflex for?

You should take Keflex for as long as your doctor recommends. This may be different for each person and will depend on the type of infection being treated.

Is Keflex available in generic form?

Yes, Keflex is available in generic form. Generic medications have the same active ingredient as the brand name and are usually more affordable.

What are the most common side effects of Keflex?

The most common side effects of Keflex include nausea, vomiting, diarrhea, headache, and rash. More serious side effects include abdominal pain, difficulty breathing, dizziness, and seizures.

Can Keflex be used to treat a urinary tract infection?

Yes, Keflex can be used to treat a urinary tract infection. It works by killing the bacteria that cause the infection.

Are there any foods I should avoid while taking Keflex?

You should avoid eating dairy products such as milk, cheese, or yogurt while taking Keflex as they can reduce the effectiveness of the medication.

What are the signs of an allergic reaction to Keflex?

The signs of an allergic reaction to Keflex include itching, rash, difficulty breathing, and swelling of the face, lips, or tongue.

Can Keflex be used to treat a bladder infection?

Yes, Keflex can be used to treat a bladder infection. It works by killing the bacteria that cause the infection.

Can Keflex cause nausea?

Yes, Keflex can cause nausea in some people. It is important to drink plenty of fluids while taking this medication to help prevent dehydration.

Is Keflex safe for elderly patients?

Yes, Keflex is safe for elderly patients when taken as prescribed by your doctor. Your doctor may adjust the dosage depending on your age and medical condition.

Can Keflex be used to treat strep throat?

Yes, Keflex can be used to treat strep throat and other bacterial infections.

Can Keflex be used to treat a skin infection?

Yes, Keflex can be used to treat a skin infection. It works by killing the bacteria that cause the infection.