Sebivo
Sebivo Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sebivo is a brand name. Its generic name is Telbivudine.
etcIntroduction
Sebivo is an antiretroviral medication used to treat HIV infection and to reduce the risk of acquiring HIV. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by blocking the activity of one of the enzymes needed for HIV replication.Uses For
Sebivo is used to treat HIV infection in adults and children over 3 years of age. It is used to reduce the risk of acquiring HIV in people who have had contact with an infected person. It works by blocking the activity of one of the enzymes needed for HIV replication.Mechanism of Action
Sebivo works by blocking the activity of reverse transcriptase, an enzyme that HIV needs to replicate. By blocking this enzyme, telbivudine prevents HIV from replicating and spreading in the body.How Long Does It Take to Work?
Sebivo works quickly, with HIV levels dropping within weeks of starting treatment. It may take several months for levels to reach an undetectable level. To maintain an undetectable viral load, telbivudine must be taken regularly as prescribed.Absorption
Sebivo is rapidly and completely absorbed from the gastrointestinal tract after oral administration.Route of Elimination
Sebivo is eliminated primarily by the kidneys in the form of metabolites.Dosage
The recommended dosage of telbivudine for adults and children over 3 years of age is 600 mg taken orally once daily. For children under 3 years of age, the recommended dosage is 10 mg/kg per day, up to a maximum of 600 mg/day.Administration
Sebivo should be taken orally once daily with or without food. It is important to take telbivudine exactly as prescribed. Taking too much or too little of the medication can reduce its effectiveness.Side Effects
Common side effects of telbivudine include headache, nausea, fever, vomiting, and rash. Contact your doctor if you have any of these symptoms.Toxicity
Sebivo is generally well tolerated, with few reported cases of serious toxicity. Rare cases of nephrotoxicity (a type of kidney damage) have been reported.Precautions
Sebivo should be used with caution in people with kidney or liver dysfunction. It should also be used with caution in pregnant or breastfeeding women.Interaction
Sebivo may interact with other medications, including other antiretroviral medications and certain antibiotics. Talk to your doctor before starting any new medications.Disease Interaction
Sebivo may interact with other diseases or conditions, including hepatitis B infection and kidney or liver dysfunction. It should be used with caution in people with these conditions.Drug Interaction
Sebivo may interact with other medications, including antiretroviral medications and antibiotics. Talk to your doctor before starting any new medications.Food Interactions
Sebivo should be taken with or without food. Taking it with food may reduce the chance of stomach upset.Pregnancy Use
It is not recommended to use telbivudine during pregnancy as it may cause harm to the unborn baby.Lactation Use
Sebivo should not be used during breastfeeding as the active ingredient can pass into breast milk and cause harm to the baby.Acute Overdose
If you think you or someone else has overdosed on telbivudine, contact a poison control center immediately.Contraindication
Sebivo is contraindicated in people with known hypersensitivity to the medication.Use Directions
Sebivo should be taken exactly as prescribed by your doctor. The recommended dose is 600 mg once daily, taken orally with or without food. Do not change your dose without talking to your doctor first.Storage Condition
Sebivo should be stored at room temperature in a moisture-proof container. Keep out of reach of children and pets.Volume of Distribution
The volume of distribution of telbivudine is 28.4 L.Half life
The half-life of telbivudine is 4 hours.Clearance
The clearance of telbivudine is 0.925 L/h per hour.Here you find in details version of Sebivo
Some Frequently Asked Questions About Sebivo
https://www.medicinesfaq.com/brand/sebivo,
,
,
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:63624,
http://www.hmdb.ca/metabolites/HMDB0015394,
http://www.genome.jp/dbget-bin/www_bget?drug:D06675,
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=159269,
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508706,
https://www.chemspider.com/Chemical-Structure.140081.html,
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088372,
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=474128,
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=63624,
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL374731,
https://zinc.docking.org/substances/ZINC000000002159,
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000698,
http://www.pharmgkb.org/drug/PA164760861,
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/LLT,
http://www.rxlist.com/cgi/generic/tyzeka.htm,
https://www.drugs.com/cdi/telbivudine.html,
https://en.wikipedia.org/wiki/Telbivudine,