Sanctura XR

Sanctura XR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sanctura XR is a brand name. Its generic name is Trospium.

Introduction

Sanctura XR is a muscarinic receptor antagonist medicine typically used to treat bladder symptoms of an overactive bladder, including frequent urination and urinary incontinence. It helps the bladder to store more urine without involuntary contractions, and makes it easier to control urine release. It is sold under the brand name Sanctura.

Uses For

Sanctura XR is used to treat an overactive bladder with symptoms of urinary urgency, frequency, and urge incontinence. It is also used to reduce muscle spasms in the urinary tract that can cause frequent nighttime urination in adults.

Mechanism of Action

Sanctura XR works by blocks contractions of muscles in the bladder and helps the bladder to store more urine. This helps control urinary release, making it easier to hold urine during the day and night, and relieves urinary urgency and frequency.

How Long Does It Take to Work?

Sanctura XR usually begins to work within two hours after taking the medication, but the full effects can take up to a week to be seen.

Absorption

Sanctura XR is absorbed from the gastrointestinal tract, with about 76% absorption from the stomach and small intestine.

Route of Elimination

Most of the trospium is eliminated via the kidneys while the rest is excreted in the feces.

Dosage

The recommended dose of Sanctura XR is 20 mg twice daily. This dose should be taken with a full glass of water, one hour before meals. The dose should not be increased without consulting a doctor.

Administration

Sanctura XR can be taken with or without food. It should not be crushed, chewed or broken before taking it.

Side Effects

The most common side effects of taking Sanctura XR are dry mouth, constipation, headache, dizziness, blurred vision, nausea, swelling or pain in the arms or legs, and urinary retention.

Toxicity

The toxicity of Sanctura XR is very low. Cases of overdose with this medication have not been reported.

Precaution

Before taking Sanctura XR, it is important to tell the doctor about any medications or supplements that the patient is already taking, as well as any pre-existing conditions.

Interactions

Sanctura XR may interact with other medications that are known to have an effect on the bladder or urinary tract. These include antidepressants, other bladder or urinary medications, other antimuscarinic agents, antidepressants, and other medications that affect the central nervous system.

Disease Interactions

Sanctura XR may interact with certain diseases, including glaucoma, bladder obstruction, myasthenia gravis, an enlarged prostate, and uncontrolled high blood pressure.

Drug Interactions

Sanctura XR may interact with certain drugs, including anticholinergics, MAO inhibitors, central nervous system stimulants, narcotics, antidepressants, and diuretics.

Food Interactions

Foods that may interact with Sanctura XR include alcohol, spicy or acidic foods, sugar, or caffeine, as these can irritate the bladder.

Pregnancy Use

Sanctura XR is not recommended for use in pregnant women unless absolutely necessary. It is important to talk to your doctor before taking this medication if pregnant.

Lactation Use

Sanctura XR is not recommended for use by nursing mothers. It is important to talk to your doctor before taking this medication if breastfeeding.

Acute Overdose

An overdose of Sanctura XR may cause symptoms such as dry mouth, constipation, dizziness, drowsiness, and/or confusion. If you or someone you know has taken an overdose of this medication, it is important to seek emergency medical attention.

Contraindication

Sanctura XR is contraindicated in people with urinary or intestinal obstruction, megacolon, gastric retention, narrow-angle glaucoma, or hypersensitivity to any of its components.

Use Directions

Take Sanctura XR exactly as directed by your doctor or the directions on the medication label. Do not take more or less of it than prescribed and do not stop taking it without consulting a doctor.

Storage Condition

Store Sanctura XR at room temperature, away from light and moisture, and keep out of reach of children.

Volume of Distribution

The volume of distribution of Sanctura XR is 7.8 L/kg.

Half Life

The half-life of Sanctura XR is 14 hours.

Clearance

The clearance of Sanctura XR is 5.6 L/h/kg.

Here you find in details version of Sanctura XR

Some Frequently Asked Questions About Sanctura XR