roxonin
roxonin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? roxonin is a brand name. Its generic name is Loxoprofen.
Introduction
roxonin is an anti-inflammatory drug which belongs to a group of medications called Non-Steroidal Anti-Inflammatory Drugs (medically known as NSAIDs). It works by reducing hormones that cause inflammation and pain in the body. roxonin is used to treat various types of pain such as musculoskeletal pain (joints, joints and tendons), migraine headache, toothache, menstrual cramps, and rheumatoid arthritis.
Uses_For
roxonin is used to treat various types of inflammation and pain, such as: musculoskeletal pain (of the joints, tendons, and muscles), migraine headache, toothache, menstrual cramps, and rheumatoid arthritis.
Mechanism of Action
roxonin works by blocking the enzyme cyclooxygenase, which is involved in the production of hormones that cause inflammation and pain in the body. This helps to reduce the signs and symptoms of inflammation and pain.
How Long Does it Take to Work?
roxonin starts to work as soon as it is taken and the effects may last up to 8 hours.
Absorption
roxonin is rapidly absorbed when taken orally. The maximum concentration in the blood (Cmax) occurs approximately 1 hour after ingestion.
Route of Elimination
roxonin is mostly eliminated through the kidneys. Approximately 95% of the drug is found in the urine, while the rest is found in the feces.
Dosage
The recommended dose for adults is 50 to 60 mg of loxoprofen taken orally up to three times daily. The maximum dose should not exceed 240 mg per day. Children should not take loxoprofen and pregnant or nursing women should only take loxoprofen with doctor’s approval.
Administration
roxonin can be taken orally with or without food. Swallow the tablet whole with a glass of water. Do not break, crush, or chew the tablet.
Side Effects
Common side effects of loxoprofen include headache, dizziness, nausea, vomiting, diarrhea, constipation, stomach pain, skin rash, and itching. If you experience any of these side effects, contact your health care provider.
Toxicity
roxonin is generally well tolerated but if taken in high doses, it can cause serious side effects such as liver damage, kidney failure, or gastrointestinal bleeding.
Precaution
Before taking loxoprofen, inform your doctor if you have any of the following medical conditions: kidney or liver disease, high blood pressure, asthma, heart or blood vessel disease, or if you are pregnant or nursing.
Interactions
roxonin may interact with other medications such as anticoagulants, nonsteroidal anti-inflammatory drugs, corticosteroids, lithium, antiviral medications, and medications used to treat high blood pressure. Tell your doctor about all medications and supplements you are taking.
Disease Interaction
roxonin should be used with caution in people with kidney or liver disease, hypertension, heart or blood vessel disease, asthma, or history of stomach ulcer. It should also be used with caution in the elderly as they have an increased risk of adverse effects.
Drug Interaction
roxonin may interact with other medications such as anticoagulants, nonsteroidal anti-inflammatory drugs, corticosteroids, lithium, antiviral medications, and medications used to treat high blood pressure. Tell your doctor about all medications and supplements you are taking.
Food Interactions
No food interaction studies have been done with loxoprofen. However, avoid taking loxoprofen with alcohol as it may increase the risk of stomach problems.
Pregnancy Use
roxonin should not be used during pregnancy as it may harm the unborn baby. If you are pregnant or planning to become pregnant, talk to your doctor before taking loxoprofen.
Lactationuse
roxonin should not be used while breastfeeding as it may pass into breast milk and may harm the nursing baby. Talk to your doctor before taking loxoprofen if you are breastfeeding.
Acute Overdose
If you overdose on loxoprofen, contact your doctor or poison control center right away. The most common symptoms of an overdose are nausea, vomiting, and abdominal pain.
Contraindication
roxonin is contraindicated in people with known hypersensitivity to any of the components of the drug or to other nonsteroidal anti-inflammatory drugs. Also, it should not be used in people with active peptic ulcer, gastrointestinal bleeding, kidney or liver problems, and uncontrolled hypertension.
Use Direction
Take loxoprofen exactly as prescribed by your doctor. Do not exceed the recommended dose. Do not take loxoprofen with alcohol or other medications that contain aspirin or ibuprofen.
Storage Condition
roxonin should be stored in a cool, dark place and away from direct sunlight. The drug should also be kept away from children and pets.
Volume of Distribution
roxonin has a volume of distribution of approximately 5.57 L/kg.
Half Life
The elimination half-life of loxoprofen is approximately 2 to 3 hours.
Clearance
The clearance rate of loxoprofen is approximately 0.59 mL/min/kg.
Here you find in details version of roxonin