Roxithromycin
Roxithromycin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Roxithromycin is a brand name. Its generic name is Roxithromycin.
Roxithromycin Introduction
Roxithromycin is a semi-synthetic macrolide antibiotic used to treat bacterial infections. This drug belongs to a class of drugs known as macrolide antibiotics, which work by inhibiting the growth of bacteria. It is used to treat a wide range of bacterial infections, including respiratory infections, skin and ear infections, pneumonia, sexually transmitted infections (STIs), and other infections.
Uses for Roxithromycin
Roxithromycin is used to treat a wide range of bacterial infections, such as: respiratory infections, skin and ear infections, pneumonia, sexually transmitted infections (STIs), and other infections.
Mechanism of Action
Roxithromycin works by targeting the 50S ribosomal subunit of bacterial cell walls and inhibiting their growth, thereby preventing the spread of bacteria in the body.
How Long Does It Take to Work?
Roxithromycin starts working within a few days of taking the medication. It may take several weeks for the full effects of the drug to be felt.
Absorption
Roxithromycin is well absorbed from the gastrointestinal tract, with peak concentrations of the drug occurring 1 to 2 hours after ingestion. It is also absorbed via rectal administration, with peak concentrations of the drug being achieved 30 minutes after administration.
Route of Elimination
Roxithromycin is mainly eliminated via the kidneys and excreted in the urine. Some of the drug is eliminated via the bile and feces as well.
Dosage
The recommended adult dosage of Roxithromycin is 150 mg twice daily, taken on an empty stomach. The dosage for children aged 6 to 12 is 7.5 mg/kg twice daily and 3.5 mg/kg once daily for children aged 2 to 6. The dose for both adults and children may be adjusted depending on individual factors.
Administration
Roxithromycin is usually taken orally, either with water or on an empty stomach. It can also be administered rectally, with the dose being adjusted accordingly.
Side-Effect
Common side-effects of Roxithromycin include nausea, diarrhea, headache, dizziness, and abdominal pain. Other possible side-effects include, but are not limited to, rash, itching, hives, anemia, and liver problems.
Toxicity
Roxithromycin is generally well tolerated when used as prescribed. However, there is a risk of serious toxicity, including liver failure and renal failure, if the drug is taken in large doses or for prolonged periods of time. If any signs of toxicity occur, it is important to stop taking the drug immediately and contact your doctor.
Precautions
Before taking Roxithromycin, it is important to tell your doctor about any other drugs or supplements you are taking, as well as any allergies you may have. This drug should also not be taken if you have a history of liver or kidney disease, as it can make these conditions worse. Additionally, it is important to drink plenty of fluids while taking this medication.
Interactions
Roxithromycin is known to interact with certain drugs, such as antacids, anticoagulants, and certain antibiotics. It is important to tell your doctor about all the drugs and supplements you are taking in order to reduce the risk of interactions. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxithromycin.
Disease Interaction
Roxithromycin can interact with certain diseases, such as liver and kidney disease. It is important to tell your doctor about any chronic medical conditions you have before taking this medication.
Drug Interaction
Roxithromycin can interact with certain drugs, such as antacids, anticoagulants, and certain antibiotics. It is important to tell your doctor about all the drugs and supplements you are taking in order to reduce the risk of interactions. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxithromycin.
Food Interactions
Roxithromycin can interact with certain foods, such as dairy and other dairy products. It is important to ask your doctor about any dietary restrictions before taking this drug. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxithromycin.
Pregnancy Use
Roxithromycin is generally not recommended for use during pregnancy. It is important to tell your doctor if you are pregnant or planning to become pregnant before taking this medication.
Lactation Use
It is not known whether Roxithromycin is safe for use during lactation. It is important to tell your doctor if you are breastfeeding or planning to breastfeed before taking this medication.
Acute Overdose
An overdose of Roxithromycin can lead to serious side-effects, such as liver and kidney toxicity, and should only be taken as prescribed. If an overdose is suspected, it is important to seek medical attention immediately.
Contraindication
Roxithromycin should not be used by individuals with a known hypersensitivity to the drug or any of its components. Additionally, it is contraindicated in patients with a history of liver or kidney disease. It is also contraindicated in pregnant and breastfeeding women.
Use Direction
Roxithromycin should be taken as prescribed by your doctor and should not be taken in large doses or for prolonged periods of time. Additionally, it is important to take the medication with plenty of water.
Storage Conditions
Roxithromycin should be stored at a temperature between 15-30°C, away from heat and light. Additionally, it is important to keep the medication away from children and pets.
Volume of Distribution
The volume of distribution of Roxithromycin is approximately 0.77L/kg.
Half Life
The half-life of Roxithromycin is approximately 19 hours.
Clearance
Roxithromycin has a total clearance of approximately 0.3 mL/min/kg.
Here you find in details version of Roxithromycin
Some Frequently Asked Questions About Roxithromycin
What is Roxithromycin?
Roxithromycin is an antibiotic medicine used to treat a wide variety of bacterial infections. It belongs to the macrolide class of antibiotics which work by preventing bacteria from multiplying and spreading.
How does Roxithromycin work?
Roxithromycin works by stopping the growth of certain bacteria that cause infections. It does this by interfering with the production of proteins that are needed for bacterial growth and multiplication. By doing this, Roxithromycin stops the bacteria from spreading and causes the infection to resolve.
Can Roxithromycin be taken with other medications?
Yes, Roxithromycin can be taken with other medications. However, it is important to tell your doctor or pharmacist about any other medications you are taking and discuss any possible interactions. Certain other medications may increase or decrease the effectiveness of Roxithromycin.
What are some common side effects of Roxithromycin?
Some common side effects of Roxithromycin include nausea, vomiting, stomach pain, diarrhea, and headache. If any of these side effects become severe or if you experience any other side effects, contact your doctor or pharmacist immediately.
What should I do if I miss a dose of Roxithromycin?
If you miss a dose of Roxithromycin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for a missed one.
How long does it take for Roxithromycin to work?
It usually takes about 1 to 2 days for Roxithromycin to start working. However, the amount of time it takes for the medication to work depends on the type and severity of the infection being treated.
What should I do if I overdose on Roxithromycin?
If you or someone else has overdosed on Roxithromycin, seek emergency medical attention immediately. Symptoms of an overdose may include nausea, vomiting, and stomach pain.
Is Roxithromycin safe for pregnant women?
Yes, Roxithromycin is generally considered safe for pregnant women. However, it is important to speak to your doctor about any potential risks before starting this medication. Your doctor will be able to decide if Roxithromycin is the right medication for you.
Can Roxithromycin be used to treat bacterial infections in children?
Yes, Roxithromycin can be used to treat bacterial infections in children. However, it is important to consult a doctor before giving this medication to a child. The doctor will be able to assess the risks and determine the correct dosage.
Can Roxithromycin be used to treat urinary tract infections?
Yes, Roxithromycin can be used to treat certain types of urinary tract infections. However, it is important to speak to your doctor before starting this medication to make sure that it is the right treatment for you.
What should I do if I experience any allergic reactions to Roxithromycin?
If you experience any signs of an allergic reaction to Roxithromycin, such as a rash, hives, swelling of the face, lips, tongue, or throat, or difficulty breathing, stop taking the medication immediately and speak to your doctor. You may need to be hospitalized if the reaction is severe.
Does Roxithromycin interact with any other medications?
Yes, Roxithromycin may interact with other medications. It is important to tell your doctor or pharmacist about all medications you are taking, including over-the-counter drugs and herbal supplements, as some medications may increase or decrease the effectiveness of Roxithromycin. Your doctor may also recommend a different medication.
What should I do if experience diarrhea while taking Roxithromycin?
If you experience diarrhea while taking Roxithromycin, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help stop the diarrhea. However, if your diarrhea persists or if it is accompanied by fever or blood, contact your doctor immediately.
Can Roxithromycin be used to treat sinus infections?
Yes, Roxithromycin can be used to treat certain types of sinus infections. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to assess the appropriateness of Roxithromycin as a treatment option.
Can Roxithromycin be taken with alcohol?
No, it is not recommended to take Roxithromycin with alcohol. Drinking alcohol while taking Roxithromycin may increase the risk of certain side effects, including nausea, vomiting, and headaches.
Can Roxithromycin be used to treat skin infections?
Yes, Roxithromycin can be used to treat certain types of skin infections. However, it is important to speak to your doctor before starting this medication as there may be other options for treatment. Your doctor will be able to assess your infection and decide if Roxithromycin is the right medication for you.
What should I do if I experience joint pain while taking Roxithromycin?
If you experience joint pain while taking Roxithromycin, contact your doctor. Your doctor can assess the cause of your joint pain and suggest other medications or treatments if necessary.
Can Roxithromycin be used to treat sexually transmitted infections (STIs)?
Yes, Roxithromycin can be used to treat certain types of sexually transmitted infections. However, it is important to speak to your doctor before starting this medication. Not all STIs can be treated with Roxithromycin, and your doctor may recommend different treatment options depending on your particular situation.
What should I do if I experience nausea and vomiting while taking Roxithromycin?
If you experience nausea and vomiting while taking Roxithromycin, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help relieve your symptoms. However, if your symptoms persist or worsen, contact your doctor.
Can Roxithromycin be used to treat strep throat?
Yes, Roxithromycin can be used to treat strep throat. However, it is important to speak to your doctor before starting this medication. Your doctor will be able to assess the severity of your infection and be able to determine the most appropriate treatment.
Does Roxithromycin interact with birth control pills?
Yes, Roxithromycin can interact with some birth control pills. It is important to discuss any medications you are taking with your doctor and pharmacist. If you are taking birth control pills, your doctor may recommend an alternative medication or a different type of birth control.
What should I do if I experience dizziness while taking Roxithromycin?
If you experience dizziness while taking Roxithromycin, it is important to speak to your doctor. Your doctor may adjust your dosage or suggest another medication. Do not drive or operate heavy machinery if you are feeling dizzy.
Should I take Roxithromycin with food?
Yes, it is usually recommended to take Roxithromycin with food. Taking this medication with food may help to reduce the risk of stomach upset. It is also important to drink plenty of fluids while taking this medication.
Can Roxithromycin be used to treat bronchitis?
Yes, Roxithromycin can be used to treat certain types of bronchitis. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to determine the most appropriate treatment.
Can Roxithromycin be used to treat strep throat in children?
Yes, Roxithromycin can be used to treat certain types of strep throat in children. However, it is important to speak to your doctor before giving this medication to a child. Your doctor will assess the severity of the infection and determine the most appropriate treatment.
What should I do if I experience headaches while taking Roxithromycin?
Headaches are a common side effect of taking Roxithromycin. If you experience headaches while taking this medication, it is important to speak to your doctor. Your doctor may recommend medications or treatments to help alleviate your symptoms.
Can Roxithromycin be used to treat gonorrhea?
Yes, Roxithromycin can be used to treat certain types of gonorrhea. However, it is important to speak to your doctor before starting this medication. Not all cases of gonorrhea can be treated with Roxithromycin, and your doctor may recommend other treatment options.
Does Roxithromycin have any interactions with other medications?
Yes, Roxithromycin may interact with other medications. It is important to tell your doctor or pharmacist about all medications you are taking, including over-the-counter drugs and herbal supplements, as some medications may increase or decrease the effectiveness of Roxithromycin. Your doctor may also recommend a different medication.
Can Roxithromycin be used to treat a uti?
Yes, Roxithromycin can be used to treat certain types of urinary tract infections. However, it is important to speak to your doctor before starting this medication to make sure that it is the right treatment for you.
What is the recommended dosage of Roxithromycin?
The recommended dosage of Roxithromycin varies depending on the type and severity of the infection being treated. It is important to speak to your doctor about the correct dosage for your particular situation.
What should I do if I experience an upset stomach while taking Roxithromycin?
If you experience an upset stomach while taking Roxithromycin, it is important to drink plenty of fluids and eat bland, easily digestible foods. You may also take an over-the-counter medication to help reduce stomach upset, such as an antacid. However, if your symptoms persist or worsen, contact your doctor.
Can Roxithromycin be used to treat ear infections?
Yes, Roxithromycin can be used to treat certain types of ear infections. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to recommend the most appropriate treatment.
Is there anything I should avoid while taking Roxithromycin?
Yes, there are a few things you should avoid while taking Roxithromycin. Firstly, you should avoid taking other medications without first speaking to your doctor or pharmacist. You should also avoid drinking alcohol and avoid activities that require you to be alert, such as driving, if you experience any side effects.
Can Roxithromycin be used to treat bacterial infections in pets?
Yes, Roxithromycin can be used to treat certain types of bacterial infections in pets. However, it is important to speak to your veterinarian before giving this medication to your pet. Your veterinarian will assess the severity of the infection and be able to determine the most appropriate treatment for your pet.
Do I need to take Roxithromycin with food?
Yes, it is usually recommended to take Roxithromycin with food. Taking this medication with food may help to reduce the risk of stomach upset. It is also important to drink plenty of fluids while taking this medication.
What should I do if I experience nausea or vomiting while taking Roxithromycin?
If you experience nausea or vomiting while taking Roxithromycin, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help relieve your symptoms. However, if your symptoms persist or worsen, contact your doctor.
Can I take other medications while taking Roxithromycin?
Yes, other medications can be taken while taking Roxithromycin. However, it is important to tell your doctor or pharmacist about any other medications you are taking. Certain medications may interact with Roxithromycin and increase or decrease its effectiveness.